Evaluation of Cold Chain Management Performance for Temperature-Sensitive Pharmaceuticals at Public Health Facilities Supplied by the Jimma Pharmaceuticals Supply Agency Hub, South... by Diriba Feyisa, Awol Jemal, Temesgen Aferu, Fikadu Ejeta, Alem Endeshaw

“…Forty-seven (47) public health facilities in Southwest Ethiopia were evaluated using checklists adopted from the Logistic Indicators Assessment Tool, Vaccine Management Assessment Tool, and Logistic System Assessment Tool. …”
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Archival and Newly Isolated Historical <i>Bacillus anthracis</i> Strains Populate the Deeper Phylogeny of the A.Br.075(Sterne) Clade by Markus Antwerpen, Peter Braun, Wolfgang Beyer, Dirk Aldenkortt, Michael Seidel, Gregor Grass

“…Finally, some of the terminal clusters of the clade named A.Br.Eu-Sterne appear to be replete with (near) identical isolates, possibly a result of widespread use of the Sterne vaccine and of its re-isolation from vaccination-related animal anthrax outbreaks. …”
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Prevalence, Infectivity, and Associated Risk Factors of Hepatitis B Virus among Pregnant Women in Yirgalem Hospital, Ethiopia: Implication of Screening to Control Mother-to-Child T... by Anteneh Amsalu, Getachew Ferede, Setegn Eshetie, Agete Tadewos, Demissie Assegu

“…Among the study participants, 35.4% were aware of MTCT of HBV and only 12 (2.5%) have taken HBV vaccine. Conclusions. High prevalence of HBsAg and HBeAg as well as low awareness and practices of HBV prevention methods suggests that perinatal transmission of HBV might be the prevailing mode of HBV transmission in the study area. …”
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Exploring factors influencing childhood immunization status in East Africa using multilevel ordinal logistic regression analysis by Aster Addisu Dires, Demeke Lakew Workie, Abay Kassa Teklie

“…IntroductionChildhood vaccinations are crucial in safeguarding children from infectious diseases and are recognized as one of the most cost-effective public health interventions. …”
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Retrospective study on the cumulative incidence of milk fever in parturient cows: a case study in the United Arab Emirates by Shaikha Ahmed Alshehhi, Temesgen Mohammed, Aboma Zewude, Berecha Bayissa, Asha Antony, Berhanu Adnew Degafa, Gobena Ameni

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Challenges faced by community health volunteers in offering sexual and reproductive health care services to young women during the COVID-19 pandemic in Khwisero and Nairobi in Keny... by Mariam F. Yusuf, Mariam F. Yusuf, Mariam F. Yusuf, Washington Onyango-Ouma, Jacinta Victoria S. Muinde, Cynthia Khamala Wangamati

“…The challenges included distrust by the community as a result of the interaction between anti-COVID-19 measures and other past and present health interventions such as vaccines for other diseases, insufficient personal protective gear and equipment (PPEs), limited human and financial resources to address community needs, limited and poor training on response to misinformation that led to vaccine hesitancy, and mental strain from stigma and burnout.ConclusionDuring pandemics, governments should provide adequate personal protective gear and financial and human resources for CHVs' work as they deliver SRH services to the community under risky conditions. …”
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Serological Survey of Foot-and-Mouth Disease Virus in Buffaloes (Syncerus caffer) in Zambia by T. K. W. Sikombe, A. S. Mweene, John Muma, C. Kasanga, Y. Sinkala, F. Banda, M. Mulumba, E. M. Fana, C. Mundia, M. Simuunza

“…Therefore livestock reared at interface with the game parks should be included in all routine FMDV vaccination programmes.…”
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An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice. by Paromita Bag, Durbadal Ojha, Hemanta Mukherjee, Umesh Chandra Halder, Supriya Mondal, Nidhi S Chandra, Suman Nandi, Ashoke Sharon, Mamta Chawla Sarkar, Sekhar Chakrabarti, Debprasad Chattopadhyay

“…Till date no effective vaccine is available, while the existing therapy frequently yielded drug resistance, toxicity and treatment failure. …”
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Microbial metabolites and immune modulation by Hassan Ghasemi

“…SCFAs, along with PSA, have shown promise as vaccine adjuvants by boosting antigen-specific immune responses and enhancing both the magnitude and quality of protective immunity. …”
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First Report of SNPs Detection in TMEM154 Gene in Sheep from Poland and Their Association with SRLV Infection Status by Magdalena Materniak-Kornas, Katarzyna Piórkowska, Katarzyna Ropka-Molik, Adrianna Dominika Musiał, Joanna Kowalik, Anna Kycko, Jacek Kuźmak

“…Since the infection is incurable and no vaccine is available, another approach is necessary to control SRLV infections. …”
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A worldwide look into long COVID-19 management: an END-COVID survey by Mattia Nigro, Claudia Valenzuela, Francisco Arancibia, Mark Cohen, David C.L. Lam, Ryan C. Maves, Barbara Rath, Steven Q. Simpson, Yuanlin Song, Sotirios Tsiodras, James D. Chalmers, Stefano Aliberti

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Antiviral Activity of the Marine Haptophyta <i>Diacronema lutheri</i> by Eleonora Montuori, Annalisa Ambrosino, Gerardo Della Sala, Costanza Ragozzino, Gianluigi Franci, Carla Zannella, Anna De Filippis, Donatella de Pascale, Massimiliano Galdiero, Chiara Lauritano

“…There are no drugs available for most viral infections and for many not even a vaccine. The marine kingdom is characterized by a huge chemical diversity; however, there is currently on the market only one drug derived from the sea with antiviral properties, called Ara-A. …”
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Ethical issues raised in the care of the elderly during the SARS-CoV-2 pandemic and possible solutions for the future: a systematic review of qualitative scientific literature by Mohamed Amine Bouchlaghem, Zoé Estey-Amyot, Erika Ethier, Miruna Anohim, Marie-Laurence Ouellet-Pelletier, Lyse Langlois, Félix Pageau

“…The analysis of the data of 17 studies has allowed the emergence of 2 main themes of ethical dilemmas: 1) access to care (3 subthemes: A) triage decisions for admission, B) access to the intensive care unit and C) vaccine allocation) and 2) infection control decisions (2 subthemes: (D) isolation and E) autonomy). …”
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Systematic assessment of COVID-19 host genetics using whole genome sequencing data. by Axel Schmidt, Nicolas Casadei, Fabian Brand, German Demidov, Elaheh Vojgani, Ayda Abolhassani, Rana Aldisi, Guillaume Butler-Laporte, DeCOI host genetics group, T Madhusankha Alawathurage, Max Augustin, Robert Bals, Carla Bellinghausen, Marc Moritz Berger, Michael Bitzer, Christian Bode, Jannik Boos, Thorsten Brenner, Oliver A Cornely, Thomas Eggermann, Johanna Erber, Torsten Feldt, Christian Fuchsberger, Julien Gagneur, Siri Göpel, Tobias Haack, Helene Häberle, Frank Hanses, Julia Heggemann, Ute Hehr, Johannes C Hellmuth, Christian Herr, Anke Hinney, Per Hoffmann, Thomas Illig, Björn-Erik Ole Jensen, Verena Keitel, Sarah Kim-Hellmuth, Philipp Koehler, Ingo Kurth, Anna-Lisa Lanz, Eicke Latz, Clara Lehmann, Tom Luedde, Carlo Maj, Michael Mian, Abigail Miller, Maximilian Muenchhoff, Isabell Pink, Ulrike Protzer, Hana Rohn, Jan Rybniker, Federica Scaggiante, Anna Schaffeldt, Clemens Scherer, Maximilian Schieck, Susanne V Schmidt, Philipp Schommers, Christoph D Spinner, Maria J G T Vehreschild, Thirumalaisamy P Velavan, Sonja Volland, Sibylle Wilfling, Christof Winter, J Brent Richards, DeCOI, André Heimbach, Kerstin Becker, Stephan Ossowski, Joachim L Schultze, Peter Nürnberg, Markus M Nöthen, Susanne Motameny, Michael Nothnagel, Olaf Riess, Eva C Schulte, Kerstin U Ludwig

“…Here, we present the results of whole genome sequencing in 1,220 mainly vaccine-naïve individuals with confirmed SARS-CoV-2 infection, including 827 hospitalized COVID-19 cases. …”
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Unbiased identification of cell identity in dense mixed neural cultures by Sarah De Beuckeleer, Tim Van De Looverbosch, Johanna Van Den Daele, Peter Ponsaerts, Winnok H De Vos

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Malaria exposure remodels the plasma proteome of Ghanaian children by Aisha M. Mohammed, Charles Ochieng’ Olwal, Andrea Fossati, Nancy K. Nyakoe, Jacqueline M. Fabius, Martin Gordon, Benjamin J. Polacco, Danielle L. Swaney, Gordon A. Awandare, Nevan J. Krogan, Mehdi Bouhaddou, Yaw Bediako

“…Although the lack of an effective vaccine has hindered malaria elimination, studies have reported on individuals acquiring natural immunity to malaria in the context of high malaria exposure. …”
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Measles and Pregnancy: Immunity and Immunization—What Can Be Learned from Observing Complications during an Epidemic Year by Rosalia Ragusa, Armando Platania, Mario Cuccia, Gaetano Zappalà, Gabriele Giorgianni, Placido D’Agati, Maria Alessandra Bellia, Marina Marranzano

“…During a measles outbreak, gynaecologists and midwives should be active proponents of vaccination administration and counteract any vaccine hesitancy not only in patients but also among health care workers.…”
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Mutations in the <i>A34R</i> gene increase the immunogenicity of vaccinia virus by S. N. Shchelkunov, T. V. Bauer, S. N. Yakubitskiy, A. A. Sergeev, A. S. Kabanov, S. A. Pyankov

“…Vaccination is the most simple and reliable approach of protection to virus infections. …”
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Single-cell transcriptomics of bronchoalveolar lavage during PRRSV infection with different virulence by Byeonghwi Lim, Seung-Chai Kim, Hwan-Ju Kim, Jae-Hwan Kim, Young-Jun Seo, Chiwoong Lim, Yejee Park, Sunirmal Sheet, Dahye Kim, Do-Hwan Lim, Kyeongsoon Park, Kyung-Tai Lee, Won-Il Kim, Jun-Mo Kim

“…Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant economic losses in the global swine industry due to its high genetic diversity and different virulence levels, which complicate disease management and vaccine development. This study evaluated longitudinal changes in the immune cell composition of bronchoalveolar lavage fluid and the clinical outcomes across PRRSV strains with varying virulence, using techniques including single-cell transcriptomics. …”
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Multiple gene-deletion vaccinia virus Tiantan strain against mpox by Yilong Zhu, Dapeng Li, Renshuang Zhao, Minghua Chen, Yue Li, Xia Yang, Hongyue Mao, Xiao Li, Yiquan Li, Chao Shang, Xianzhu Xia

“…Because of the safety risks and side effects of vaccination with live vaccinia virus (VACV) strain Tian Tan (VTT), we constructed two gene-deleted VTT recombinants (TTVAC7 and TTVC5). …”
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