Modelling and Analyzing the Potential Controls for Neospora caninum Infection in Dairy Cattle Using an Epidemic Approach by Yue Liu, Ioannis Magouras, Wing-Cheong Lo

“…Potential controls including medication, test-and-cull, and vaccination are proposed and analyzed, and the corresponding reproduction numbers are derived. …”
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The voice of people’s perspective on the future of health resilience post pandemic hits: A numerically scaled survey in 19 provinces in Indonesia by Nurlaila Ika, Amalya Dewi Meta

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An HPLC-based Assay to Study the Activity of Cyclic Diadenosine Monophosphate (C-di-AMP) Synthase DisA from Mycobacterium smegmatis by Avisek Mahapa, Sudhanshu Gautam, Arti Rathore, Dipankar Chatterji

“…Additionally, c-di-AMP demonstrates potent adjuvant properties, particularly when administered alongside the Bacillus Calmette–Guérin (BCG) vaccine through mucosal routes. Because of its pivotal role in bacterial signaling and host immune response, this molecule has garnered significant interest from the pharmaceutical industry. …”
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STUDY OF DNA TRANSFORMATION DYNAMICS IN ВНК-21/2-17 CELL CULTURE USING FLOW CYTOMETRY DURING FMD VIRUS REPRODUCTION by M. N. Guseva, M. A. Shevchenko, D. V. Mikhalishin, V. V. Mikhalishin, B. L. Manin

“…The study of FMDV cytopathic effect in ВНК-21/2-17 cells demonstrated that one of the optimization trends in culture vaccine production include proliferation inhibitory factor use at a certain cell cycle phase.…”
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Mathematical Analysis of Malaria Epidemic: Asymptotic Stability With Cost-Effectiveness Study by Sacrifice Nana-Kyere, Baba Seidu, Kwara Nantomah

“…Mathematical models of infectious diseases have been the steering wheel, driving scientists towards elucidation of the dynamic behaviour of epidemics and providing tailored strategic management of diseases. With the ongoing vaccination programs for vector-borne diseases, the research proposes a nonlinear differential equation model for the malaria disease that provides public health with a shift from the classical understanding of nonpharmaceutical preventive malaria control to pharmaceutical measures of vaccines. …”
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Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency by Sílvia Bacalhau, Cristina Freitas, Rosalina Valente, Deolinda Barata, Conceição Neves, Katrin Schäfer, Annelie Lubatschofski, Ansgar Schulz, João Farela Neves

“…In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. …”
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Family Practitioners and Sexually Transmitted Diseases by Marc Steben

“…Counselling about hepatitis B virus infection involves risk evaluation, patient education, evaluation of immune status to hepatitis B virus and discussions about vaccine needs and availability.…”
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3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists by Ji Hwan Kim, Seunghyun Ahn, Dongsoo Koh, Young Han Lee, Yoongho Lim, Soon Young Shin

“…Therefore, compound 6 can be used as an innate immune modulator to develop antiviral agents and vaccine adjuvants.…”
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Measuring influencing factors affecting mortality rates during the COVID-19 pandemic by Jih-Shong Wu, Kuo-Kuang Huang

“…Results This study yielded several key findings: (1) There remains a 33% margin for improvement in the global mortality rate concerning the COVID-19 pandemic; (2) During the initial stage of the pandemic, when an effective vaccine was not yet available, implementing public health control policies could reduce both the infection and mortality rates; (3) Areas characterised by higher population densities, a greater proportion of individuals aged 65 and over, and elevated prevalence rates of diabetes demonstrated higher mortality rates; and (4) Increasing vaccination coverage emerged as an effective strategy for reducing mortality rates. …”
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Profile and complexity of travel medicine consultations in Chile: unicentric cross-sectional study by Thomas Weitzel

“…Objective To analyse the spectrum, vaccination needs and pretravel advice complexity of travellers presenting at a travel medicine clinic in Santiago, Chile.Design Cross-sectional study.Setting Pretravel consultations in a private healthcare centre in Chile, an ‘emerging market’ country in South America.Participants Travellers (n=1341) seeking pretravel advice at the Travel Medicine Program of Clínica Alemana, Santiago, from April 2016 to March 2018.Primary and secondary outcome measures Demographical and travel characteristics, indications for travel vaccines and malaria prophylaxis, and complexity of travel consultations.Results Of 1341 travellers, 51% were female; the median age was 33 years. …”
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ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics by Lennox Chitsike, John Krstenansky, Penelope J. Duerksen-Hughes

“…The COVID-19 pandemic that began in late 2019 continues with new challenges arising due to antigenic drift as well as individuals who cannot or choose not to take the vaccine. There is therefore an urgent need for additional therapies that complement vaccines and approved therapies such as antibodies in the fight to end or slow down the pandemic. …”
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Gene Carriers and Transfection Systems Used in the Recombination of Dendritic Cells for Effective Cancer Immunotherapy by Yu-Zhe Chen, Xing-Lei Yao, Yasuhiko Tabata, Shinsaku Nakagawa, Jian-Qing Gao

“…Reported research in animal studies indicated that vaccine immunity could be a promising alternative therapy for cancer patients. …”
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Predictive Biomarkers of Bacillus Calmette-Guérin Immunotherapy Response in Bladder Cancer: Where Are We Now? by Luís Lima, Mário Dinis-Ribeiro, Adhemar Longatto-Filho, Lúcio Santos

“…The most effective therapeutic option for managing nonmuscle invasive bladder cancer (NMIBC), over the last 30 years, consists of intravesical instillations with the attenuated strain Bacillus Calmette-Guérin (the BCG vaccine). This has been performed as an adjuvant therapeutic to transurethral resection of bladder tumour (TURBT) and mostly directed towards patients with high-grade tumours, T1 tumours, and in situ carcinomas. …”
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A broadly neutralizing antibody against the SARS-CoV-2 Omicron sub-variants BA.1, BA.2, BA.2.12.1, BA.4, and BA.5 by Zhe Chen, Leilei Feng, Lei Wang, Li Zhang, Binyang Zheng, Hua Fu, Fengdi Li, Ligai Liu, Qi Lv, Ran Deng, YanLi Xu, Yongfeng Hu, Jianhua Zheng, Chuan Qin, Linlin Bao, Xiangxi Wang, Qi Jin

“…With the constant evolution of the virus, Omicron and its subtypes BA.1, BA.2, BA.3, BA.4, and BA.5 have developed the capacity to evade neutralization induced by previous vaccination or infection. This evasion highlights the urgency in discovering new monoclonal antibodies (mAbs) with neutralizing activity, especially broadly neutralizing antibodies (bnAbs), to combat the virus.In the current study, we introduced a fully human neutralizing mAb, CR9, that targets Omicron variants. …”
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De novo design of protein minibinder agonists of TLR3 by Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King

“…Several nucleic acid-based TLR3 agonists have been explored clinically as vaccine adjuvants in cancer and infectious disease, but present substantial manufacturing and formulation challenges. …”
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Studying immunotherapeutic properties of the conjugate based on BCG antigens with betulonic acid in guinea pigs infected with <i>Mycobacterium scrofulaceum</i> by I. N. Koshkin, V. S. Vlasenko, N. A. Dengis

“…The experiment showed that the inoculation of Mycobacterium scrofulaceum into guinea pigs activates cationic proteins and neutrophil myeloperoxidase, and on experiment day 42 (preceded by mycobacteria withdrawal from the body) their concentration reduced to the level of the control group. The vaccine administration induced a more active intracellular phagocyte metabolism during the entire observation period, which resulted in the elimination of nontuberculosis mycobacteria in animals as early as day 7 after treatment with the conjugate. …”
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Molecular and Cellular Mechanisms of Immunosenescence: Modulation Through Interventions and Lifestyle Changes by Luca Pangrazzi, Andreas Meryk

“…This phenomenon, characterized by alterations in both innate and adaptive immunity, increases susceptibility to infections, reduces vaccine efficacy, and contributes to the development of age-related diseases. …”
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PHYLOGENETIC ANALYSIS OF FMDV ISOLATES RECOVERED IN POST-SOVIET STATES AND MONGOLIA IN 2016 by A. M. Timina, N. G. Zinyakov, A. V. Scherbakov, D. A. Lozovoy

“…The FGBI “ARRIAH's" objectives as a Regional Reference Laboratory/ Centre include continuous FMDV monitoring in post-Soviet states, detection of new genetic virus variants and matching their antigenic properties with antigenic properties of available vaccine virus strains. The paper demonstrates results of phylogenetic analysis of foot-and-mouth disease virus (FMDV) that caused the disease in Armenia, Zabaikalsky Krai (Russia), Middle Asia and Mongolia in 2016. …”
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Awareness and Health-Seeking Behaviour Regarding Japanese Encephalitis in Kurnool: A Cross-Sectional Study by Karthik S Murthy, P Sudha Kumari, K Ravi Naik, M V S Nagaraju

“…Regarding the awareness about vaccination for JE only 44 of the subjects were aware of JE vaccination for children and adults. …”
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Air Pollution Variation During COVID-19 Pandemic Using Satellite and On-site Measurement Data in Six Provinces in Iran by Maryam Zare Shahne, Amirhossein Noori, Mehdi Alizade Attar

“…Base on wavelet transform, implemented on ground-measurment of PM2.5, the PM2.5 concentration increased in early 2021 from the value in baseline period, due to eased restriction and expansion of public COVID-19 vaccine in all considered provinces.…”
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