Rapid quantitative analysis of double-stranded plasmid DNA with capillary gel electrophoresis for applications in quality control and radiation research by Marc Benjamin Hahn

“…Abstract The quantification of different structures, isoforms and types of damage in plasmid DNA is of importance for applications in radiation research, DNA based bio-dosimetry, and pharmaceutical applications such as vaccine development. The standard method for quantitative analysis of plasmid DNA damage such as single-strand breaks (SSB), double-strand breaks (DSB) or various types of base-damage is Agarose gel electrophoresis (AGE). …”
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Trafficked Proteins—Druggable in Plasmodium falciparum? by Jasmin Lindner, Kamila Anna Meissner, Isolmar Schettert, Carsten Wrenger

“…Annually this parasitic disease leads to more than half a million deaths; most of these are children in Africa. An effective vaccine is not available, and the treatment of the disease is solely dependent on chemotherapy. …”
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Circulating Dynamics of SARS-CoV-2 Variants between April 2021 and February 2022 in Turkey by Murat Sayan, Ayse Arikan, Murat Isbilen

“…The diagnosis of new variants and monitoring their potential effects on diagnosis, therapeutics, and vaccines by genomic sequencing is essential to manage global public crises. …”
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Applied Comparison of Meta-analysis Techniques by Li Wang, Colin Lewis-Beck, Elyse Fritschel, Erdem Baser, Onur Baser

“…**Results:** All three techniques showed a statistically significant effects from the vaccination. However, once covariates were added, efficacy diminished. …”
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COVID-19 Pandemic in Brunei Darussalam by Wei Shan Ang, Jodi Woan-Fei Law, Vengadesh Letchumanan, Yong Sze Ong, Yatinesh Kumari, Long Chiau Ming, Loh Teng-Hern Tan

“…The key success factors are effective pandemic containment measures, public communication strategy, and enhanced surveillance mechanisms supported by the mass testing program and contact tracing. A national vaccination strategy ensuring adequate vaccine distribution and effective administration has been rolled out to render lasting protection against the infection. …”
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Virulence and pathogenicity of group B Streptococcus: Virulence factors and their roles in perinatal infection by Christina J. Megli, Sophia M. Carlin, Elizabeth J. Giacobe, Gideon H. Hillebrand, Thomas A. Hooven

“…We conclude by addressing current efforts in vaccine development, underscoring the need for effective prevention strategies against this pervasive pathogen.…”
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B-Lymphocytes from a Population of Children with Autism Spectrum Disorder and Their Unaffected Siblings Exhibit Hypersensitivity to Thimerosal by Martyn A. Sharpe, Taylor L. Gist, David S. Baskin

“…The role of thimerosal containing vaccines in the development of autism spectrum disorder (ASD) has been an area of intense debate, as has the presence of mercury dental amalgams and fish ingestion by pregnant mothers. …”
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Hamster and Murine Models of Severe Destructive Lyme Arthritis by Erik Munson, Dean T. Nardelli, Brian K. Du Chateau, Steven M. Callister, Ronald F. Schell

“…However, severe destructive Lyme arthritis can be induced by infecting irradiated hamsters or mice and immunocompetent Borrelia-vaccinated hamsters, mice, and interferon-gamma- (IFN-γ-) deficient mice with viable B. burgdorferi. …”
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Computer-Aided Analysis of Multiple SARS-CoV-2 Therapeutic Targets: Identification of Potent Molecules from African Medicinal Plants by Franklyn Nonso Iheagwam, Solomon Oladapo Rotimi

“…The COVID-19 pandemic, which started in Wuhan, China, has spread rapidly over the world with no known antiviral therapy or vaccine. Interestingly, traditional Chinese medicine helped in flattening the pandemic curve in China. …”
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Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal by Kamal Ranabhat, Bhuvan Saud, Saroj Adhikari, Suraj Bhattarai, Rojan Adhikari, Bhoj Raj Luitel, Mahesh Raj Sigdel

“…In this case report, we present the level of anti-SARS-CoV-2 antibody of three kidney transplant recipients after vaccination against COVID-19 virus. All three cases had received two doses of Oxford-AstraZeneca COVID-19 vaccine AZD1222 (ChAdOx1). …”
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Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model by Elena Ufimtseva

“…Monolayer cultures of cells that migrated from individual granulomas were established in the proposed culture settings for mouse spleen and lung granulomas induced by in vivo exposure to BCG vaccine. The cellular composition of individual granulomas was analyzed. …”
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A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective against HSV-2 intravaginal challenge in mice. by Elisa Rossetti, Marija Vujadinovic, Ella van Huizen, Jeroen Tolboom, Hanneke Schuitemaker, Feng Yao, Roland Zahn, Eirikur Saeland

“…We have designed an adenoviral vector type 35 (Ad35)-based vaccine encoding the HSV-2 major surface antigen gD2 (Ad35.HSV.gD2). …”
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Phylodynamic reconstruction of major chicken infectious anemia virus clades epidemiology, dispersal, and evolution by Giovanni Franzo, Matteo Legnardi, Francesca Poletto, Riccardo Baston, Giulia Faustini, Mattia Cecchinato, Claudia Maria Tucciarone

“…Both clades exhibited no significant competition and similar global patterns, characterized by a progressive increase until about 2000, when a transient decline was observed for some years, potentially reflecting the increasing use of vaccines. Accordingly, although significant selective pressures were shaping viral evolution, comparable strengths were estimated in the two viral populations. …”
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Antivirals for the treatment of mild and moderate COVID-19 in South Africa by R Perumal, V Naidoo, S Govender, T N Gengiah

“… While the majority of COVID‐19 cases in South Africa (SA) are mild, patients with severe COVID‐19 requiring hospitalisation present with significant morbidity and mortality and place a substantial burden on healthcare services. Given the low vaccine uptake in SA and other low‐ and middle‐income countries in sub‐Saharan Africa, the high prevalence of comorbidities and limited healthcare system capacity, evidence‐based interventions that reduce the risk of severe disease and death should be considered for implementation. …”
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The Simultaneous Effects of Spatial and Social Networks on Cholera Transmission by Sophia Giebultowicz, Mohammad Ali, Mohammad Yunus, Michael Emch

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Sikap Ibu Terhadap Pemberian Imunisasi Measles Rubella Secara Tepat Waktu Selama Pandemi Covid-19 by Dianti Oktadevi, Ayun Sriatmi, Wulan Kusumastuti

“…Conclusion: The mother's attitude was not optimal because there were various problems with the mother's attitude, so it is hoped that the mother will increase knowledge, share experiences with peer groups, and if unable to attend, ask for family assistance, while health center is expected to carry out promotions, education about measles-rubella immunization and also coordinate with health office regarding vaccine stock Keywords:  immunization, measles-rubella, timeliness…”
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Importance of Lipopolysaccharide and Cyclic β-1,2-Glucans in Brucella-Mammalian Infections by Andreas F. Haag, Kamila K. Myka, Markus F. F. Arnold, Paola Caro-Hernández, Gail P. Ferguson

“…This paper will focus on the role of LPS and cyclic β-1,2-glucans in Brucella-mammalian infections and discuss the use of mutants, within the biosynthesis pathway of these cell envelope structures, in vaccine development.…”
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Pandemic mitigation: Bringing it home by Tom Reichert

“…In the US, national, regional and even institutional plans for ameliorating the effects of pandemic influenza focus on stockpiling antiviral medications, early production and distribution of vaccine, mass and personal social distancing, and a number of personal hygiene activities. …”
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Convalescent plasma therapy in severe coronavirus disease-2019: A narrative review by Rasmi Ranjan Sahoo, Kasturi Hazarika, Prashant Bafna, Manesh Manoj, Anupam Wakhlu

“…Until, a specific antiviral therapy or an effective vaccine is made available, the consideration for use of convalescent blood products, especially plasma, is warranted. …”
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Experimental Investigation on an Absorption Refrigerator Driven by Solar Cells by Zi-Jie Chien, Hung-Pin Cho, Ching-Song Jwo, Chao-Chun Chien, Sih-Li Chen, Yen-Lin Chen

“…Therefore, this system can be expected to be used in remote areas for refrigeration of food and beverages in outdoor activities in remote and desert areas or long-distance road transportation of food or low temperature refrigeration of vaccine to avoid the deterioration of the food or the vaccines.…”
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