Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross-stage recognition of glutamate-rich repeats by Axelle Amen, Randy Yoo, Amanda Fabra-García, Judith Bolscher, William JR Stone, Isabelle Bally, Sebastián Dergan-Dylon, Iga Kucharska, Roos M de Jong, Marloes de Bruijni, Teun Bousema, C Richter King, Randall S MacGill, Robert W Sauerwein, Jean-Philippe Julien, Pascal Poignard, Matthijs M Jore

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Seroconversion and dynamics of IgG anti-SARS-CoV-2 antibodies during the pandemic: A two-month observation cohort study on the population of Sleman in Indonesia. by Jajah Fachiroh, Septi Kurnia Lestari, Dewi Kartikawati Paramita, Bagas Suryo Bintoro, Fatwa Sari Tetra Dewi, Lutfan Lazuardi, Cici Permata Rusadi, Erti Nur Sagenah, Eggi Arguni

“…Group 1 (seronegative-unvaccinated individuals; 50 subjects); Group 2 (seronegative-vaccinated individuals; 27 subjects); Group 3 (seropositive-unvaccinated individuals; 25 subjects); and Group 4 (seropositive-vaccinated individuals; 282 subjects). …”
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Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders by Jianqiu Pan, Xu Shen, Hongjia Ouyang, Junfeng Sun, Sui Liufu, Danli Jiang, Wenjun Chen, Siyue Peng, Danning Xu, Yunbo Tian, Yunmao Huang, Jianhua He

“…On days 0, 15 and 30, ganders in the immunized group were immunized with OPN5-KLH protein vaccine, and ganders in the control were immunized with the same amount of blank emulsified vaccine. …”
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Specific immune response to M. tuberculosis and ability to in vitro control mycobacterial replication are not impaired in subjects with immune-mediated inflammatory disease and tub... by Chiara Farroni, Anna Maria Gerarda Altera, Andrea Salmi, Valentina Vanini, Valentina Vanini, Gilda Cuzzi, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Giovanni Delogu, Giovanni Delogu, Ivana Palucci, Settimia Sbarra, Alessandra Aiello, Andrea Picchianti-Diamanti, Gina Gualano, Fabrizio Palmieri, Delia Goletti, Elisa Petruccioli

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Immunisation schedule of the Pediatric Spanish Association: 2024 recommendations by Francisco José Álvarez García, Antonio Iofrío de Arce, Javier Álvarez Aldeán, Elisa Garrote Llanos, Lucía López Granados, María Luisa Navarro Gómez, Valentín Pineda Solas, Irene Rivero Calle, Jesús Ruiz-Contreras, Ignacio Salamanca de la Cueva, Pepe Serrano Marchuet, Francisco José Álvarez García, Antonio Iofrío de Arce, Javier Álvarez Aldeán, María Garcés-Sánchez, Elisa Garrote Llanos, Abián Montesdeoca Melián, María Luisa Navarro Gómez, Valentín Pineda Solas, Irene Rivero Calle, Jesús Ruiz-Contreras, Pepe Serrano Marchuet

“…The AEP 2025 Vaccination and Immunization Schedule recommended for children, adolescents and pregnant women residing in Spain features the following novelties:Due to the increase in measles cases and outbreaks in recent years, we recommend advancing the second dose of measles, mumps and rubella (MMR) vaccine to 2 years of age.As a consequence of the above, since many autonomous communities (ACs) use the quadrivalent vaccine for the second dose of MMR and varicella vaccines, we recommend, for all ACs, advancing the second dose of varicella vaccine to 2 years of age.Due to the very significant increase in cases of pertussis since late 2023 and especially in 2024, we recommend advancing the dose of Tdap given in adolescence to 10–12 years of age.To complete protection against meningococcal disease in adolescence, we recommend vaccination against MenB at age 12 years.We believe that vaccination against seasonal influenza should be routine up to age 18 years, but given the disappointing coverage in children aged 6–59 months, we currently consider that improving this coverage should be prioritised, extending vaccination to children and adolescents aged 5–18 years once this objective has been achieved.Among other aspects, the routine immunization tables for healthy individuals and risk groups, the use of the new extended-valence conjugate vaccines against pneumococcal disease, routine vaccination at 4 months of age with MenACWY and vaccination against SARS-CoV-2 for individuals aged more than 6 months with risk factors remain unchanged with respect to the 2024 schedule. …”
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Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities. by Kristina N Delgado, Melissa J Caimano, Isabel C Orbe, Crystal F Vicente, Carson J La Vake, André A Grassmann, M Anthony Moody, Justin D Radolf, Kelly L Hawley

“…The results support the use of ECL-based vaccines and suggest that loop-specific antibodies promote spirochete clearance via Fc receptor-independent as well as Fc receptor-dependent mechanisms.…”
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Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…They have also contributed to groundbreaking discoveries, including the introduction of the first mRNA vaccine (against COVID-19), and have improved certain imaging and diagnostic techniques, too. …”
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A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi. by Bum Ju Park, Sang Taek Heo, Misun Kim, Jeong Rae Yoo, Eun Jin Bae, Su Yeon Kang, Sunghoon Park, Kyeo Re Han, Keun Hwa Lee, Jae Myun Lee, Hyeyoung Lee, Yoon-Jae Song

“…Currently, there is no vaccine for O. tsutsugamushi, and its infection is treated with antibiotics such as doxycycline. …”
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Molecular pathogenesis of Cryptosporidium and advancements in therapeutic interventions by Lu Yilong, Zhang Xiaoning, Guan Zhiyu, Ji Rui, Peng Fujun, Zhao Chunzhen, Gao Wei, Gao Feng

“…The treatment of cryptosporidiosis is challenging due to the current lack of an effective treatment or vaccine. Ongoing research is focused on understanding the molecular pathogenesis of Cryptosporidium and developing pharmacological treatments. …”
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COVID-19 Diagnosis from Blood Gas Using Multivariate Linear Regression by Faruk Ayata, Ebubekir Seyyarer

“…Issues such as methods developed to understand the spread mechanisms of the disease, prevention measures, vaccine and drug research are among the top priorities of the world agenda. …”
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mosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae by Brady Dolan, Tomás Correa Gaviria, Yuemei Dong, Peter Cresswell, George Dimopoulos, Yu-Min Chuang, Erol Fikrig

“…Targeting mosGILT can therefore interfere with the Plasmodium life cycle in the mosquito and potentially serve as a transmission-blocking vaccine.…”
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Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205 by Luciana D’Apice, Valerio Costa, Rossella Sartorius, Maria Trovato, Marianna Aprile, Piergiuseppe De Berardinis

“…The filamentous bacteriophage fd, codisplaying antigenic determinants and a single chain antibody fragment directed against the dendritic cell receptor DEC-205, is a promising vaccine candidate for its safety and its ability to elicit innate and adaptive immune response in absence of adjuvants. …”
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Comparison Of Bacillus anthracis Prepared Used Antigens As ‎Diagnostic kit Of Anthrax In Laboratoy Animals.‎ by Al- Jebouri A.J. ‎, Al- Khatib G.M.‎

“…A comparison was carried out among the prepared antigens using skin test in non- vaccinated guinea pigs which showed negative results. …”
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Antibody dynamics in dogs submitted to different canine visceral leishmaniasis treatment protocols by Eliesse Pereira Costa, Gisele Vaz Aguirre Samoel, Gilneia da Rosa, Vanessa Osmari, Michelli Lopes de Souza, Luís Felipe Dias Lopes, Fernanda Silveira Flôres Vogel, Sônia de Avila Botton, Luís Antônio Sangioni

“…Twenty-one dogs naturally infected by Leishmania spp. were grouped based on the treatment protocol: G1 (n=4) received allopurinol; G2 (n=10) allopurinol with miltefosine; and G3 (n=7) allopurinol, miltefosine and Leish-Tec® vaccine. The dogs were monitored monthly for a period of one year. …”
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Nontypeable Haemophilus influenzae Otitis Media: Mastoiditis and Meningitis Complicated with Central Venous Thrombosis in an Immunocompetent Child by Erdem Gönüllü, Nesrin Özkan, Ahmet Soysal, Engin Acıoğlu, Emine Betül Tavil, Selin Nar Ötgün, Metin Karaböcüoğlu

“…Implementation of the Haemophilus influenzae type B (Hib) conjugate vaccine brought about a reduction in the number of cases and morbidity from type B but an increase in nontypeable strain infections. …”
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The modification of conventional liposomes for targeted antimicrobial delivery to treat infectious diseases by Nnamdi Ikemefuna Okafor, Omobolanle Ayoyinka Omoteso, Yahya E. Choonara

“…Abstract Some of the most crucial turning points in the treatment strategies for some major infectious diseases including AIDS, malaria, and TB, have been reached with the introduction of antimicrobials and vaccines. Drug resistance and poor effectiveness are key limitations that need to be overcome. …”
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A Comprehensive Review of the Development and Therapeutic Use of Antivirals in Flavivirus Infection by Aarti Tripathi, Shailendra Chauhan, Renu Khasa

“…Millions of infections every year pose a serious threat to worldwide public health, encouraging scientists to develop a better understanding of the pathophysiology and immune evasion mechanisms of these viruses for vaccine development and antiviral therapy. Extensive research has been conducted in developing effective antivirals for flavivirus. …”
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Passive Protection of Diabetic Rats with Antisera Specific for the Polysaccharide Portion of the Lipopolysaccharide Isolated from Pseudomonas pseudomallei by Larry E Bryan, Sallene Wong, Don E Woods, David AB Dance, W Chaowagul

“…The wide distribution of the polysaccharide antigen among isolates of P pseudomallei used in this study and the protective role of antibody to the conjugated polysaccharide antigen suggest potential as a vaccine.…”
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Optimal control of chikungunya disease: Larvae reduction, treatment and prevention by Djamila Moulay, M. A. Aziz-Alaoui, Hee-Dae Kwon

“…Three main efforts are considered in order to limit the virus transmission. Indeed, there is no vaccine nor specific treatment against chikungunya, that is why the main measures to limit the impact of such epidemic have to be considered. …”
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Mutation analysis of SHP2, SOS1, and SOS2 related to dysregulation of Ras/MAPK pathway in Noonan syndrome by Nihayatul Karimah

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