Research note: Establishment of a multiplex PCR detection system for different infectious bronchitis virus strain genotypes in laying hens by Changjing Zhao, Cheng Yuan, Qingsen Zhao, Aihong Xia, Yaqing Dong, Shuying Xu, Shihan Chen, Yue Yuan, Yongjuan Wang

“…This study produced a method for the fast detection and identification of five strains of infectious bronchitis virus (IBV), including the currently prevalent wild-type QX and G Ⅵ-1 strains, in addition to the Mass, 4/91, and LDT3 strains that are used as vaccines. Based on the spike 1 (S1) glycoprotein gene sequences of the IBV Mass, QX, G Ⅵ-1, 4/91, and LDT3 strains, five sets of customized primers, showing excellent specificity, were designed and synthesized to target the appropriate conserved sequences. …”
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Prevalence and factors associated with uptake of pre-exposure prophylaxis amongst women vulnerable to HIV who received HIV antibodies in Antibody Mediated Prevention HVTN703/HPTN08... by Bernard Ngara, Bekezela Siziba, Nyaradzo Mavis Mgodi, Tariro Dianah Chawana, Miria Chitukuta, Pamela Grace Mukwekwerere, Muchaneta Bhondai-Mhuri, Zvavahera Mike Chirenje, Felix Godwin Sivukile Mhlanga

“…The AMP study evaluated the safety and efficacy of Vaccine Research Center 01 broadly neutralising monoclonal antibody in reducing acquisition of HIV-1 infection in women in sub-Saharan Africa. …”
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Mixed-methods reproductive health knowledge, attitudes and practices survey of IDPs, returnees and host communities in Jonglei State, South Sudan by William Clemmer, Mounir Lado, Lynn Lieberman Lawry, Rachel Gabor, Jacques Katele, Lazarus Baak Madut, Katina Sommers, David Manuel, Claire Nadolski, Tracey Koehlmoos

“…For respondents with children<2 years of age, 68·9% (95% CI 64·7 to 72·7) had received three doses of Penta valent vaccine. Females and males reported similar lifetime GBV rates.Conclusion Conflict and flooding in the remote survey areas are significant barriers to MNCH. …”
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Development of the cultural tailoring score (CTS): a scoring instrument to assess cultural tailoring of health messaging by Claudia Parvanta, Kayleigh Murray, Samantha Boddupalli, Natalie Erasme, Rheese McNab, Vijay Prajapati, Arabel Severe, Aura Reyes, Richard Harner, Rhonda Holliday

“…It is based on research demonstrating the importance of: (1) Levels of engagement of the intended audience in the production, (2) use of understandable and culturally meaningful language, incorporation of (3) surface cultural cues and (4) deeper cultural constructs, (5) presence of a narrative to bind the information and cultural elements into a relatable story, and (6) factors associated with concrete psychological construal level (“now,” “here,” “you”).Methods We document a trial of the cultural tailoring score conducted by graduate students identifying as Filipino, Haitian, or Hispanic/Latinx reviewing 17 ads promoting COVID-19 vaccine that had been pretested during the pandemic for perceived effectiveness with convenience samples of these same ethnic groups.Results We achieved a combined Spearman’s Rank Correlation rho of 0.45 between the cultural tailoring score and perceived effectiveness ranking of all 17 ads (individual cultural groupings range from Spearman’s rho 0.45 to 0.90), suggesting that cultural components were moderately to strongly associated with perceived effectiveness. …”
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Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…Summary: Background: Aging increases disease susceptibility and reduces vaccine responsiveness, highlighting the need to better understand the aging immune system and its clinical associations. …”
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Gardnerella vaginalis-binding IgA in the urethra of sexually experienced males by Rachel Liu, R. M. Galiwango, Daniel Park, Sanja Huibner, Maliha Aziz, Aggrey Anok, James Nnamutete, Yahaya Isbirye, John Bosco Wasswa, Deo Male, Godfrey Kigozi, Aaron A. R. Tobian, Jessica L. Prodger, Cindy Liu, Bryan Coburn, Rupert Kaul

“…Prospective studies of the host-microbe relationship in the urethra may have implications for the development of vaccines against sexually-transmitted bacteria. Video Abstract…”
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Antimicrobial susceptibility profiles of Mycoplasma hyosynoviae strains isolated from five European countries between 2018 and 2023 by Ulrich Klein, Dorottya Földi, Eszter Zsófia Nagy, Lilla Tóth, Nikolett Belecz, Karola Költő, Enikő Wehmann, Szilvia Marton, Marianna Merenda, Michele Gastaldelli, Salvatore Catania, Joachim Spergser, Ute Siesenop, Philip Vyt, Krisztián Bányai, Zsuzsa Kreizinger, Wouter Depondt, Miklós Gyuranecz

“…In the absence of a commercial vaccine improvement of housing conditions and antibiotic therapy are the only options to alleviate the clinical signs. …”
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Perceptions, Uses, and Information Sources of Medical Cannabis Among Patients With Cancer by Vera Qu, BA, Caressa Hui, MD, Jennifer Hall, BA, Kekoa Taparra, MD, PhD, Tanaya Kollipara, BA, Sandy Trieu, MD, Beth Beadle, MD, PhD, Scott Soltys, MD, Erqi L. Pollom, MD

“…This latter subcohort was significantly more likely to identify as Hispanic/Latino (38.5% vs 9.9%, P = .009) and less likely to be up to date on COVID-19 vaccinations (30.8% vs 8.5%, P = 0.044). Identifying as Hispanic/Latino remained significantly associated with strongly agreeing or agreeing that MC can cure cancer on bivariate analysis (odds ratio, 6.528; 95% CI, 1.477-28.715; P = .012). …”
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Defining indicators for disease burden, health outcomes, policies and barriers and facilitators to health services for migrant populations in the Middle East and North African regi... by Charles Agyemang, Ali Ardalan, Farah Seedat, Bouchra Assarag, Nuria Casamitjana, Kolitha Wickramage, Sally Hargreaves, Ana Requena-Mendez, Fouad M Fouad, Dominik Zenner, Anna Deal, Stella Evangelidou, Wafa Saidi, Chiaki Ito, Oumnia Bouaddi, Moudrick Abdellatifi, Alba Cuxart-Graell, Hassan Edries, Eman Elafef, Taha Maatoug, Anissa Ouahchi, Liv Mathilde Pampiri, Sara Arias, Adel Abdelkhalek, Ahmed Hamed Arisha, Ibrahim Ahmed Bani, Aasmaa Chaoui, Wafa Chemao-Elfihri, Kenza Hassouni, Mahmoud Hilali, Mohamed Khalis, Wejdene Mansour, Ali Mtiraoui, MENA Migrant Health Working Group, Asad Adam, Adnene Ben Haj Aissa, Salma Altyib, Hanen Ben Belgacem, Imane Belkhammar, Thomas Calvot, Luciana Ceretti, Nelly Chavassieux, Hassan Chrifi, Mohamed Douagi, Algdail Elnil, Gonzalo Fanjul, Ahmed Hamed, Abdedayem Khelifi, Lora Makhlouf, Maissa Mokni, Davide Olchini, Tarik Oufkir, Nasong Park, Giuseppe Raffa, Sandra Santafé, Alice Sironi, Fatma Temimi, Zeineb Turki

“…This protocol describes a suite of seven systematic reviews that aim to identify, appraise and synthesise the available evidence on the burden and health outcomes, policies and access (barriers and facilitators) related to these mobile populations in the region.Methods Seven systematic reviews will cover three questions to explore the: (1) burden and health outcomes, (2) policies and (3) healthcare barriers and facilitators for the following seven disease areas in migrants in the MENA region: tuberculosis, HIV and hepatitis B and C, malaria and neglected tropical diseases, diabetes, mental health, maternal and neonatal health, and vaccine-preventable diseases. We will search electronic databases for studies in any language (year 2000–2023), reference-check relevant publications and cross-check included studies with experts. …”
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BIOTECHNOLOGICAL SYSTEM FOR THE SEARCH OF SUBSTANCES WITH POTENTIAL ACTIVITY AGAINST CORONAVIRUS by M.P. Smetiukh, O.P. Trokhimenko, S.O. Soloviov, I.V. Dziublyk, O.A. Kamatskyi, I.V. Savchuk, N.A. Bobyr

“…Conclusions: As a result of the conducted research, the vaccine virus IBV H-120 was successfully adapted to cultivation conditions in ВНК-21 cell cultures, using primary trypsinized chicken embryo fibroblast cells as an intermediate system. …”
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Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China by Haoling Tang, Zhiwei Chen, Tianquan Huang, Pingping Yu, Qiao Tang, Yue Qiu, Yunling Xue, Jing Tang, Nan Cai, Hong Ren, Mingli Peng, Peng Hu

“…Interestingly, females experiencing menstruation or pregnancy exhibited a higher risk of infection, while inhaled vaccines and thymosin demonstrated a protective effect against SARS‐CoV‐2 infection. …”
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A worldwide look into long COVID-19 management: an END-COVID survey by Mattia Nigro, Claudia Valenzuela, Francisco Arancibia, Mark Cohen, David C.L. Lam, Ryan C. Maves, Barbara Rath, Steven Q. Simpson, Yuanlin Song, Sotirios Tsiodras, James D. Chalmers, Stefano Aliberti

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Description and characterization of pneumococcal community acquired pneumonia (CAP) among radiologically confirmed CAP in outpatients by Josselin Le Bel, Juliette Pinot, Toni Alfaiate, Marie Ecollan, Fanny Cussac, Raphaël Pecqueur, Marie-Pierre Revel, Cyrille Vartanian, Emmanuelle Varon, Christian Theilacker, Xavier Duval, Henri Partouche, Cédric Laouénan, Serge Gilberg

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Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry by Prasad T. Oommen, Tilmann Kallinich, Juergen Rech, Norbert Blank, Julia Weber-Arden, Jasmin B. Kuemmerle-Deschner

“…Patients continued to receive vaccinations during long-term treatment with canakinumab. …”
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Ethical issues raised in the care of the elderly during the SARS-CoV-2 pandemic and possible solutions for the future: a systematic review of qualitative scientific literature by Mohamed Amine Bouchlaghem, Zoé Estey-Amyot, Erika Ethier, Miruna Anohim, Marie-Laurence Ouellet-Pelletier, Lyse Langlois, Félix Pageau

“…The analysis of the data of 17 studies has allowed the emergence of 2 main themes of ethical dilemmas: 1) access to care (3 subthemes: A) triage decisions for admission, B) access to the intensive care unit and C) vaccine allocation) and 2) infection control decisions (2 subthemes: (D) isolation and E) autonomy). …”
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Unbiased identification of cell identity in dense mixed neural cultures by Sarah De Beuckeleer, Tim Van De Looverbosch, Johanna Van Den Daele, Peter Ponsaerts, Winnok H De Vos

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Clinical diagnosis of seasonal influenza by physicians: a retrospective observational study by Hiroyuki Kato, Tadashi Kobayashi, Hiroki Maita, Takashi Akimoto, Fumihiko Matsuoka, Shigeki Funakoshi, Hiroshi Osawa

“…The AUCs of patients with type A and B influenza were 0.78 (95% CI 0.72 to 0.84) and 0.76 (95% CI 0.70 to 0.82), respectively. The AUCs of vaccinated and unvaccinated patients were 0.80 (95% CI 0.72 to 0.88) and 0.76 (95% CI 0.63 to 0.89), respectively. …”
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Efficacy of hyperimmunized egg yolk antibodies (IgY) against Campylobacter jejuni: In Vitro and In Vivo evaluations by Nazanin Soltani, Shaban Rahimi, Pejvak Khaki, Mohammad Amir Karimi Torshizi, Bahareh Eskandari, Jesse Grimes

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Stunting and Associated Factors among Under-Five-Age Children in West Guji Zone, Oromia, Ethiopia by Eyob Afework, Selamawit Mengesha, Demelash Wachamo

“…The under-five children whose fathers had a polygamous marriage (AOR = 4.92, 95% CI: 3.46, 7.00), being female sex (AOR = 1.74, 95% CI: 1.23, 2.47), having below 4 meal frequencies (AOR = 2.95, 95% CI: 1.56, 5.58), not vaccinated (AOR = 1.75, 95% CI: 1.15, 2.67), and from poor households’ wealth status (AOR = 3.03, 95% CI: 1.63, 5.63) and also from severely food insecure household (AOR = 2.92, 95% CI: 1.36, 6.24) were short for their age compared with their counterparts. …”
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Deaths in children in England from SARS-CoV-2 infection during the first 2 years of the pandemic: a cohort study by Shamez N Ladhani, Peter Fleming, Tom Williams, Karen Luyt, Godwin Oligbu, David Odd, Sylvia Stoianova, Anna Thursby-Pelham

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