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2801
Evolutionary Traits and Genomic Surveillance of SARS-CoV-2 in South America
Published 2022-01-01“…The modeling of the molecular events and microevolution of the virus will contribute to making better decisions on public health management of the pandemic and developing accurate treatments and more efficient vaccines.…”
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2802
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2803
Global distribution of sporadic sapovirus infections: A systematic review and meta-analysis.
Published 2021-01-01“…Since the reduction of rotavirus in countries that have included rotavirus vaccines in their national immunization programs, other viruses such as norovirus and sapovirus have emerged as more common causes of AGE. …”
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2804
Mutation analysis of SHP2, SOS1, and SOS2 related to dysregulation of Ras/MAPK pathway in Noonan syndrome
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2805
Rapid quantitative analysis of double-stranded plasmid DNA with capillary gel electrophoresis for applications in quality control and radiation research
Published 2025-01-01“…Abstract The quantification of different structures, isoforms and types of damage in plasmid DNA is of importance for applications in radiation research, DNA based bio-dosimetry, and pharmaceutical applications such as vaccine development. The standard method for quantitative analysis of plasmid DNA damage such as single-strand breaks (SSB), double-strand breaks (DSB) or various types of base-damage is Agarose gel electrophoresis (AGE). …”
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2806
Chagas Disease Cardiomyopathy: Immunopathology and Genetics
Published 2014-01-01“…Chagas disease thus remains a neglected disease, with no vaccines or antiparasitic drugs proven efficient in chronically infected adults, when most patients are diagnosed. …”
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2807
Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model
Published 2013-01-01“…Monolayer cultures of cells that migrated from individual granulomas were established in the proposed culture settings for mouse spleen and lung granulomas induced by in vivo exposure to BCG vaccine. The cellular composition of individual granulomas was analyzed. …”
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2808
Polyarticular Septic Arthritis Caused by Haemophilus influenzae Serotype f in an 8-Month-Old Immunocompetent Infant: A Case Report and Review of the Literature
Published 2015-01-01“…The standard use of vaccinations against pathogens has resulted in a decreased incidence of musculoskeletal infections caused by these previously common bacterial pathogens. …”
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2809
Antiviral Activity of the Marine Haptophyta <i>Diacronema lutheri</i>
Published 2024-12-01“…There are no drugs available for most viral infections and for many not even a vaccine. The marine kingdom is characterized by a huge chemical diversity; however, there is currently on the market only one drug derived from the sea with antiviral properties, called Ara-A. …”
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2810
Chloroquine Inhibits Dengue Virus Type 2 Replication in Vero Cells but Not in C6/36 Cells
Published 2013-01-01“…Since there is no dengue vaccine available for human use, we have set out to investigate the use of chloroquine as an antiviral drug against dengue. …”
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2811
Alternative treatment methods for bovine mastitis: prospects and limitations (review)
Published 2024-09-01“…This review describes the following alternative remedies: probiotics, bacteriocins, bacteriophages, phage enzymes (endolysins), nanoparticles, plant extracts, essential oils and immunobiological agents (vaccines). Understanding the mechanisms of their action will allow recommending the best treatment option for mastitis in each specific case. …”
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2812
A Case of Mild Encephalopathy with a Reversible Splenial Lesion Associated with G5P[6]Rotavirus Infection
Published 2013-01-01“…This extremely rare genotype was detected first in Japan and is not covered by existing vaccines; this is the first sample isolated from encephalopathy patients. …”
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2813
Duke Research at Pickett: The evolution of a free-standing research site partnering with communities toward health equity advancement
Published 2025-01-01“…Catalyzed by the COVID-19 pandemic, Duke Research at Pickett, a 22 000-square-foot building with a laboratory, 30 exam rooms, and on-site parking, opened in October 2020 to support vaccine and treatment trials. Upon the lifting of many COVID-19 restrictions, and in partnership with the Research Equity and Diversity Initiative (READI) Community Advisory Council, the building was transformed to encourage community gatherings, education, and training programs. …”
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2814
Computational structure-based design of antiviral peptides as potential protein–protein interaction inhibitors of rabies virus phosphoprotein and human LC8
Published 2025-01-01“…Despite the successful development of vaccines and efforts made in drug discovery, rabies is incurable. …”
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2815
Control of Intracellular Francisella tularensis by Different Cell Types and the Role of Nitric Oxide
Published 2014-01-01“…Cells were infected with the highly virulent Schu S4 strain or with the avirulent live vaccine strain (LVS) with and without stimuli. Compared to MH-S cells, J774A.1 cells were unresponsive to stimulation and were able to control the intracellular replication of LVS bacteria, but not of Schu S4. …”
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2816
Targeting T-Cell Activation for Malaria Immunotherapy: Scoping Review
Published 2025-01-01“…The findings underscore the potential of T cells, particularly CD8+ T cells, in liver-stage defense and advocate for the exploration of advanced vaccine platforms and novel therapies, such as mRNA-based vectors and monoclonal antibodies.…”
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2817
State of the Art, Unresolved Issues, and Future Research Directions in the Fight against Hepatitis C Virus: Perspectives for Screening, Diagnostics of Resistances, and Immunization
Published 2016-01-01“…For all these reasons, even though new drugs may contribute to impacting HCV spread worldwide a preventive HCV vaccine remains a cornerstone in the road to significantly reduce the HCV spread globally, with the ultimate goal of its eradication. …”
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2818
Effects of health education using mobile technologies on caregivers’ knowledge of routine growth monitoring for children aged 9 to 24 months in Kenya
Published 2024-12-01“…Unfortunately, many caregivers cease active RGM activities once they exhaust the government-recommended vaccines. The study aimed to find out the effects of health education using mobile technologies on caregivers’ knowledge of RGM. …”
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2819
Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1
Published 2025-02-01“…However, unlike EBOV, there are no approved vaccines or treatments for SUDV, and its structural interaction with the endosomal receptor NPC1 remains unclear. …”
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2820
Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer
Published 2023-01-01“…Adaptive cell therapy, cancer vaccines, gene therapy, and monoclonal antibody therapy have all been used in gastric cancer with some initial success. …”
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