A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi. by Bum Ju Park, Sang Taek Heo, Misun Kim, Jeong Rae Yoo, Eun Jin Bae, Su Yeon Kang, Sunghoon Park, Kyeo Re Han, Keun Hwa Lee, Jae Myun Lee, Hyeyoung Lee, Yoon-Jae Song

“…Currently, there is no vaccine for O. tsutsugamushi, and its infection is treated with antibiotics such as doxycycline. …”
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Growth Phase-Dependent Proteomes of the Malaysian Isolated Lactococcus lactis Dairy Strain M4 Using Label-Free Qualitative Shotgun Proteomics Analysis by Theresa Wan Chen Yap, Amir Rabu, Farah Diba Abu Bakar, Raha Abdul Rahim, Nor Muhammad Mahadi, Rosli Md. Illias, Abdul Munir Abdul Murad

“…It is used extensively in the food industry and plays a pivotal role as a cell factory and also as vaccine delivery platforms. The proteome of the Malaysian isolated L. lactis M4 dairy strain, obtained from the milk of locally bred cows, was studied to elucidate the physiological changes occurring between the growth phases of this bacterium. …”
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THE INFLUENCE OF MOTHER'S KNOWLEDGE AND ATTITUDE ON BASIC IMMUNIZATION COVERAGE by Nina Herlina, erik ekowati, Alfida Faqih Dhea firanti, Elsya Hildatrian, Fairy Prudencia, Wanelis Wanelis, Nabilla Ramadhani

“…Background: Basic Immunization is the administration of vaccines to infants aged 0-18 months. The success of the basic immunization program in infants is supported by the important role of parents who are responsible for their babies Objective: To determine the influence of mothers' knowledge and attitudes on basic immunization coverage. …”
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Bacteria as Precision Tools for Cancer Therapy by Carmen Michán, José Prados, Juan‐Luis Ramos

“…Engineered S. typhimurium strains can generate adjuvant flagellin‐antigen complexes that function as in situ vaccines, hence increasing the immunogenic responses within tumour environment. …”
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Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity? by Sin-Yeang Teow, Alif Che Nordin, Syed A. Ali, Alan Soo-Beng Khoo

“…Deeper understanding on how exosomes promote or abate HIV infection can significantly contribute to the development of new and potent antiviral therapeutic strategy and vaccine designs.…”
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A Comprehensive Review of the Development and Therapeutic Use of Antivirals in Flavivirus Infection by Aarti Tripathi, Shailendra Chauhan, Renu Khasa

“…Millions of infections every year pose a serious threat to worldwide public health, encouraging scientists to develop a better understanding of the pathophysiology and immune evasion mechanisms of these viruses for vaccine development and antiviral therapy. Extensive research has been conducted in developing effective antivirals for flavivirus. …”
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STUDY OF DNA TRANSFORMATION DYNAMICS IN ВНК-21/2-17 CELL CULTURE USING FLOW CYTOMETRY DURING FMD VIRUS REPRODUCTION by M. N. Guseva, M. A. Shevchenko, D. V. Mikhalishin, V. V. Mikhalishin, B. L. Manin

“…The study of FMDV cytopathic effect in ВНК-21/2-17 cells demonstrated that one of the optimization trends in culture vaccine production include proliferation inhibitory factor use at a certain cell cycle phase.…”
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Immunocompatibility of Bacteriophages as Nanomedicines by Tranum Kaur, Nafiseh Nafissi, Olla Wasfi, Katlyn Sheldon, Shawn Wettig, Roderick Slavcev

“…Recently, phages have been employed as gene-delivery vectors (phage nanomedicine), for nearly half a century as tools in genetic research, for about two decades as tools for the discovery of specific target-binding proteins and peptides, and for almost a decade as tools for vaccine development. As phage applications to human therapeutic development grow at an exponential rate, it will become essential to evaluate host immune responses to initial and repetitive challenges by therapeutic phage in order to develop phage therapies that offer suitable utility. …”
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Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals by Ghyda Murad Hashim, Mehdi Shahgolzari, Kathleen Hefferon, Afagh Yavari, Srividhya Venkataraman

“…Also addressed are plant-derived anti-cancer vaccines, nanoparticles, monoclonal antibodies, and immunotherapies. …”
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From the Role of Microbiota in Gut-Lung Axis to SARS-CoV-2 Pathogenesis by Sara Ahmadi Badi, Samira Tarashi, Abolfazl Fateh, Pejman Rohani, Andrea Masotti, Seyed Davar Siadat

“…Furthermore, it has been shown that vaccine efficacy against viral respiratory infection is influenced by probiotics pretreatment. …”
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Development of a Portable Rapid Detection Method for Porcine Epidemic Diarrhea Virus Using Reverse Transcription-Recombinase-Aided Amplification Technology by Yiran Zhao, Weijie Yi, Qicheng Yang, Jiahao Li, Yanke Shan, Fei Liu

“…The continuous genetic mutations of PEDV have compromised the effectiveness of classical strain vaccines. Early detection and accurate diagnosis are therefore crucial for controlling its further spread. …”
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Validation of a Real Time PCR for Classical Swine Fever Diagnosis by Natanael Lamas Dias, Antônio Augusto Fonseca Júnior, Anapolino Macedo Oliveira, Érica Bravo Sales, Bruna Rios Coelho Alves, Fernanda Alves Dorella, Marcelo Fernandes Camargos

“…The parameters for the validation followed the specifications of the Manual of Diagnostic Tests and Vaccines for Terrestrial Animals of the World Organization for Animal Health (OIE) and the guide ABNT NBR ISO/IEC 17025:2005. …”
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Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis by Maria Eduarda Souza Guerra, Giulia Destro, Brenda Vieira, Alice S. Lima, Lucio Fabio Caldas Ferraz, Anders P. Hakansson, Michelle Darrieux, Thiago Rojas Converso

“…Some of these molecules could be used in future vaccines against this bacterium. However, there is still a lack of in vivo models to evaluate the contribution of biofilm development to disease pathogenesis. …”
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Investigation of the Proportion of Brucella abortus and Brucella melitensis in Sheep and Goat Milk by Saeid Rostami, Ehsan Rashidian, Amin Jaydari, Heidar Rahimi

“…The information provided in the present study is important for the surveillance program, as eradication programs and strategies to prevent the spread of B. abortus among small ruminants that have not been vaccinated against this microorganism may be adapted accordingly.…”
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Antivaccine, denialist, and conspiracy theorist content on Facebook. An analysis of the No to the New World Order page by Julio C. Aguila Sanchez, Carmen Castillo Rocha, Ángel R. Vargas Valencia

“…The most liked posts included two videos: one about a strike by health workers in France and another criticising vaccines. Conclusions. Based on the published content, it can be observed that 'No to the New World Order' serves as a platform for criticizing pandemic management across all fronts. …”
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COVID-19 Diagnosis from Blood Gas Using Multivariate Linear Regression by Faruk Ayata, Ebubekir Seyyarer

“…Issues such as methods developed to understand the spread mechanisms of the disease, prevention measures, vaccine and drug research are among the top priorities of the world agenda. …”
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Antibody dynamics in dogs submitted to different canine visceral leishmaniasis treatment protocols by Eliesse Pereira Costa, Gisele Vaz Aguirre Samoel, Gilneia da Rosa, Vanessa Osmari, Michelli Lopes de Souza, Luís Felipe Dias Lopes, Fernanda Silveira Flôres Vogel, Sônia de Avila Botton, Luís Antônio Sangioni

“…Twenty-one dogs naturally infected by Leishmania spp. were grouped based on the treatment protocol: G1 (n=4) received allopurinol; G2 (n=10) allopurinol with miltefosine; and G3 (n=7) allopurinol, miltefosine and Leish-Tec® vaccine. The dogs were monitored monthly for a period of one year. …”
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Knowledge and risk behaviors related with HIV infect in Communitarian General Medicine students. by Luis Manuel Padrón Velázquez, Clara Hilda Vega Blanco

“…<strong>Background: </strong>The worldwide epidemic outburst cause by the HIV and lack of effective vaccines against it make of human sexual behavior the most important element to fight this disease. …”
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Clinical Relevance of HLA Gene Variants in HBV Infection by Li Wang, Zhi-Qiang Zou, Kai Wang

“…These variations also influence the efficacy of interferon (IFN) and nucleot(s)ide analogue (NA) treatment and response to HBV vaccines. Meanwhile, discrepant conclusions were reached with different patient cohorts. …”
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Potential of Black Phosphorus in Immune-Based Therapeutic Strategies by Wenjuan Dong, Hu Wang, Hailin Liu, Chunqiao Zhou, Xuelin Zhang, Song Wang, Lin He

“…Based on the prospective phototherapy, BP with irradiation can cause a “double-kill” to tumor cells, involving tumor-structure damage induced by heat, ROS, and shockwaves and a subsequent anticancer immune response induced by in situ vaccines construction in tumor site, which is referred to as photoimmunotherapy (PIT). …”
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