Recurrent Herpetic Stromal Keratitis in Mice: A Model for Studying Human HSK by Patrick M. Stuart, Tammie L. Keadle

“…We will document both differences and similarities that derive from this fundamental difference in these models with an eye towards possible vaccines and therapies that demonstrate promise in treating HSK.…”
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The power of health economics and outcomes research (HEOR) in making decisions that matter by Oscar Herrera Restrepo

“… Deciding on approving and granting market access to new medical technologies such as pharmaceutical products, vaccines, or medical devices is a multifactorial research problem. …”
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Beyond Bell's Palsy: Cephalic Tetanus Unveiled by Lubna Khan, Samra Mansoori, Raeda Khan, Mohammad Iqbal

“… Tetanus, although rare in vaccinated regions, remains common in developing countries. …”
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Immune aging and infectious diseases by Ruochan Chen, Ju Zou, Jiawang Chen, Ling Wang, Rui Kang, Daolin Tang, Sihan Zhou, Xiuyuan Hao

“…These changes would impair defense mechanisms, increase susceptibility to infections and reduce vaccine efficacy in older adults. Cellular senescence exacerbates these issues by releasing pro-inflammatory factors, further perpetuating chronic inflammation. …”
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The Immune Response to Tumors as a Tool toward Immunotherapy by F. Pandolfi, R. Cianci, D. Pagliari, F. Casciano, C. Bagalà, A. Astone, R. Landolfi, C. Barone

“…Immunotherapy of tumors has developed several techniques: immune cell transfer, vaccines, immunobiological molecules such as monoclonal antibodies that improve the immune responses to tumors. …”
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Immunogenetic Factors Associated with Severe Respiratory Illness Caused by Zoonotic H1N1 and H5N1 Influenza Viruses by Jennifer Juno, Keith R. Fowke, Yoav Keynan

“…By better defining the role of genetic variability in influenza infection and identifying key polymorphisms that impair the host immune response or correlate with protection, we will be able to better identify at-risk populations and new targets for therapeutic interventions and vaccines. This paper will summarize known immunogenetic factors associated with susceptibility or severity of both pH1N1 and H5N1 infections and will also identify genetic pathways and polymorphisms of high relevance for future study.…”
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Imaging Early Steps of Sindbis Virus Infection by Total Internal Reflection Fluorescence Microscopy by Youling Gu, Yuanzheng Yang, Yuechueng Liu

“…Sindbis virus (SINV) is an alphavirus that has a broad host range and has been widely used as a vector for recombinant gene transduction, DNA-based vaccine production, and oncolytic cancer therapy. …”
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Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery by Wei Wang, Kepan Chen, Ting Jiang, Yiyang Wu, Zheng Wu, Hang Ying, Hang Yu, Jing Lu, Jinzhong Lin, Defang Ouyang

“…Abstract Lipid nanoparticles (LNPs) have proven effective in mRNA delivery, as evidenced by COVID-19 vaccines. Its key ingredient, ionizable lipids, is traditionally optimized by inefficient and costly experimental screening. …”
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Molecular characteristics and pathogenicity analysis of infectious laryngotracheitis virus isolated in China from 2015 to 2019 by Xuehui Zhang, Lihua Tang, Linqing Duan, Ruihua Yang, Kangchengyin Liu, Jing Zhao, Ye Zhao, Guozhong Zhang

“…Phylogenetic analysis showed that six isolates (SD2015, GD2017, SYB2018, HB201812, HB201806, and TJ2019) were classified together with CEO vaccine strains, while only one isolates LN2018 belonged to the wild-type cluster. …”
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Protein-Protein Interactions Inferred from Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences by Chuan-Ching Huang, Chuan Yi Tang

“…However, no efficient vaccine for NoVs exists because of their variable genome sequences. …”
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Canine circovirus: an emerging virus of dogs and wild canids by Farzad Beikpour, Arash Letafati, Zahra Ahmadi Fakhr, Nicoal Decaro, Sayed-Hamidreza Mozhgani

“…Prevention strategies are hindered by the lack of targeted vaccines and the virus's resilience in the environment. …”
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A symbiotic mosquito‐gut bacterium for flavivirus control by Jinglin Wang, Yibin Zhu, Jun Leng, Yulin Yuan, Yingyi Cao, Gong Cheng, Xueshan Xia

“…However, current measures, including vaccines and treatments, are often limited or ineffective. …”
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Strategies to Overcome Antileishmanial Drugs Unresponsiveness by Shyam Sundar, Anup Singh, Om Prakash Singh

“…In the absence of effective vector control measures and vaccines against leishmaniasis, effective chemotherapy remains the mainstay of treatment. …”
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Antivirals for the treatment of mild and moderate COVID-19 in South Africa by R Perumal, V Naidoo, S Govender, T N Gengiah

“… While the majority of COVID‐19 cases in South Africa (SA) are mild, patients with severe COVID‐19 requiring hospitalisation present with significant morbidity and mortality and place a substantial burden on healthcare services. Given the low vaccine uptake in SA and other low‐ and middle‐income countries in sub‐Saharan Africa, the high prevalence of comorbidities and limited healthcare system capacity, evidence‐based interventions that reduce the risk of severe disease and death should be considered for implementation. …”
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Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells by Yan Ding, Jialai Yan, Ling Huang, Jinhong Yu, Yandan Wu, Chuanlai Shen, Anning Fang

“…BackgroundAlthough the immune response of host T cells to human immunodeficiency virus (HIV) significantly influences the progression of the infection, the development of T-cell-based vaccines and therapies, as well as the clinical evaluation of specific T-cell functions, is currently markedly hindered by the absence of broad-spectrum, functionally validated HIV T-cell epitopes that account for the polymorphisms of the human leukocyte antigen (HLA) within an indicated geographic population. …”
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Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders by Jianqiu Pan, Xu Shen, Hongjia Ouyang, Junfeng Sun, Sui Liufu, Danli Jiang, Wenjun Chen, Siyue Peng, Danning Xu, Yunbo Tian, Yunmao Huang, Jianhua He

“…On days 0, 15 and 30, ganders in the immunized group were immunized with OPN5-KLH protein vaccine, and ganders in the control were immunized with the same amount of blank emulsified vaccine. …”
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Genetic profiling of extended-spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 from clinical samples among diarrheal patients in Shashemene, Ethiopia by Shimelis Teshome Ayalneh, Biruk Yeshitela Beshah, Yeonji Jeon, Ashenafi Alemu Wami, Seifegebriel Teshome, Solomon Gebreselassie, Se Eun Park, Mekonnen Teferi, Woldaregay Erku Abegaz

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Relationship between iron deficiency and severity of tuberculosis: Influence on T cell subsets by Zheyue Wang, Zhenpeng Guo, Qiang Zhang, Chenchen Yang, Xinling Shi, Qin Wen, Yuan Xue, Zhixin Zhang, Jianming Wang

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ONC213: a novel strategy to resensitize resistant AML cells to venetoclax through induction of mitochondrial stress by Jenna L. Carter, Yongwei Su, Eman T. Al-Antary, Jianlei Zhao, Xinan Qiao, Guan Wang, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Steven A. Buck, Maik Hüttemann, Joshua E. Allen, Varun V. Prabhu, Jay Yang, Jeffrey W. Taub, Yubin Ge

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Scoping review of infectious disease prevention, mitigation and management in passenger ships and at ports: mapping the literature to develop comprehensive and effective public hea... by Lemonia Anagnostopoulos, Sotirios Vasileiadis, Leonidas Kourentis, Zacharoula Bogogiannidou, Ioanna Voulgaridi, Gordon Nichols, Fani Kalala, Matthaios Speletas, Christos Hadjichristodoulou, Varvara A. Mouchtouri, the EU HEALTHY SAILING project

“…Future research could assess risk factors and PMM measure effectiveness considering vaccine-preventable, vector-borne and sexually transmitted diseases. …”
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