Heat stable and intrinsically sterile liquid protein formulations by Atip Lawanprasert, Harminder Singh, Sopida Pimcharoen, Mariangely González Vargas, Arshiya Dewan, Girish S. Kirimanjeswara, Scott H. Medina

“…Abstract Over 80% of biologic drugs, and 90% of vaccines, require temperature-controlled conditions throughout the supply chain to minimize thermal inactivation and contamination. …”
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NOVEL MUTATIONS IN THE NON-STRUCTURE PROTEIN 2 OF SARS-CoV-2 by Mohsen Nakhaei, Zohreh-Al-Sadat Ghoreshi, Mohammad Rezaei Zadeh Rukerd, Hedyeh Askarpour, Nasir

“…Conclusion: Our study suggested that the mutations as K337D and G392D modulate the stability of nsp2 and tracking viral evolution should be implemented and vaccine development updated. …”
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Serological cross-reactivity between Crimean-Congo haemorrhagic fever virus and Nairobi sheep disease virus glycoprotein C by Emmanuel A. Maze, George Booth, Georgina Limon, Sandra Belij-Rammerstorfer, Simona R. Tchakarova, Tsviatko Alexandrov, Clare Browning, Ginette Wilsden, Anna B. Ludi, Bryan Charleston, Teresa Lambe, Teresa Lambe

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Development of ¹¹¹In-Labeled Monoclonal Antibodies Targeting SFTSV Structural Proteins for Molecular Imaging of SFTS Infectious Diseases by SPECT by Takeshi Fuchigami, Mya Myat Ngwe Tun, Yusuke Tanahara, Kodai Nishi, Sakura Yoshida, Kazuma Ogawa, Morio Nakayama, Daisuke Hayasaka

“…No effective vaccines or treatments are currently available for severe fever with thrombocytopenia syndrome (SFTS), a fatal tick-borne infectious disease caused by the SFTS virus (SFTSV). …”
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A phase I, randomized, placebo‐controlled trial to evaluate the pharmacokinetics, safety, and tolerability of nirsevimab in healthy Chinese adults by Xiaomeng Mao, Xiaohan Hua, Chengyi Wu, Xiaoyun Ge, Jie Zhang, Xiaojie Wu, Robert J. Kubiak, Ulrika Wählby Hamrén, Tonya Villafana, Georgios Christou, Jannine Green, Therese Takas, Yuwen Jin

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Assessing the long-term economic impact of wheezing episodes after severe RSV disease in children from Argentina: a cost of illness analysis by Ranju Baral, Clint Pecenka, Elisabeth Vodicka, Andrea Rodríguez, Romina Libster, Julia Dvorkin, Emiliano M Sosa, Andrea Sancilio, Karina Dueñas, Carlos Rojas-Roque, Patricia B Carruitero, Fernando P Polack, Mauricio T Caballero

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Determinants maintaining healthcare personnel’s motivation during COVID-19 pandemic in Uganda by Makiko Komasawa, Myo Nyein Aung, Christopher Nsereko, Kiyoko Saito, Robert Ssekitoleko, Mitsuo Isono, Motoyuki Yuasa

“…COVID-19 knowledge was high, with over 70% answering questions correctly, although vaccine effectiveness had a slightly lower accuracy rate. …”
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Inequalities in health behaviours during the COVID-19 pandemic – a commentary by Aleksandra Herbeć

“…The focus of the pandemic response has been on health protective behaviours (e.g. update of vaccinations, isolation, and use of face covering). Health behaviours and health behaviour change (such as changes in physical activity, diet and alcohol consumption) have been socio-demographically- patterned already before the COVID-19 pandemic. …”
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The power of health economics and outcomes research (HEOR) in making decisions that matter by Oscar Herrera Restrepo

“… Deciding on approving and granting market access to new medical technologies such as pharmaceutical products, vaccines, or medical devices is a multifactorial research problem. …”
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The power of health economics and outcomes research (HEOR) in making decisions that matter by Oscar Herrera Restrepo

“… Deciding on approving and granting market access to new medical technologies such as pharmaceutical products, vaccines, or medical devices is a multifactorial research problem. …”
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Toll-Like Receptor 4 Activation in Cancer Progression and Therapy by Alja Oblak, Roman Jerala

“…Further research of the role and mechanisms of TLR4 activation in cancer may provide novel antitumor vaccine adjuvants as well as TLR4 inhibitors that could prevent inflammation-induced carcinogenesis.…”
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Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53 by Iulianna C. Taritsa, Eric T. Fossel

“…These agents can broadly be classified into six categories: the viral approach, direct modifiers of the p53 pathway, epigenetic modifiers of the p53 pathway, synthetic lethal agents, structural reactivators, and immune activating vaccines. Even these strategies have been met with limited success. …”
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Design and Optimization of E-Commerce Logistics Distribution System Based on Multiobjective Function by Hui Wen

“…The algorithm utilizes a new immune vaccine selection strategy and immune operation method, the optimization process is adaptively changed with the evolutionary algebra, combined with the parallel selection method to optimize the multiobjective logistics distribution path, and the specific steps to solve the multiobjective logistics distribution path problem are given. …”
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Some statements on medical care in the "new normal" post-covid-19 by Alfredo Darío Espinosa Brito

“…This has been possible thanks to the joint efforts of the whole of society, with its highest authorities ahead, the capacity and dedication of health professionals organized in a vigorous national health system, obtaining and applying effective native drugs and the massive immunization against SARS-COV-2, with our Cuban Abdala and Soberanas vaccines. Comments are made on a group of lessons learned during the pandemic, on the existence of many doubts and questions still unanswered, on the new risks -especially for the most vulnerable- including the so-called post-COVID syndrome, when events are held more massive outbreaks of different kinds, as well as alerting to the frequent appearance of new coronavirus’ variants and recent "waves" of patients in different countries. …”
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Sickness, Hygienic Education and Village Practice: Tuberculosis in the Life of a Cobbler by Tuija Saarinen

“…The first concord of antibiotics was received in 1947. Vaccinations against tuberculosis started on a mass scale in the following year. …”
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First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India by Aniruddha Jakharia, Biswajyoti Borkakoty, Sumi Pait, Gautam Baruah, Rahul Hazarika, Dipankar Biswas

“…Virus isolation is of paramount importance for development of vaccines, in-vitro screening of antiviral compounds, pathogenesis studies, etc., Many cell lines were studied for amplification and replication of SARS-CoV-2 and Vero cells were found to be ideal cell lines for isolation. …”
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Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications by Lifeng Li, Xinxiu Xu, Ping Cheng, Zengyuan Yu, Mingchao Li, Zhidan Yu, Weyland Cheng, Wancun Zhang, Huiqing Sun, Xiaorui Song

“…We also deliberated on the potential of K. pneumoniae OMVs in vaccine development, as diagnostic biomarkers, and as drug nanocarriers. …”
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Integrating engineered nanomaterials with extracellular vesicles: advancing targeted drug delivery and biomedical applications by Hai Jiang, Ranil Vikraman Kumarasamy, JinJin Pei, Kamaraj Raju, Gopalakrishnan Velliyur Kanniappan, Chella Perumal Palanisamy, Ion Dan Mironescu

“…Highlighting various applications, including targeted drug delivery, cancer therapy, and vaccine development, the review underscores the potential of EV-nanomaterial hybrids to leverage EVs’ innate targeting capabilities and the versatility of nanomaterials. …”
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Enhanced Immunogenicity and Affinity with A35R-Fc-Based Chimeric Protein Compared to MPXV A35R Protein by Shimeng Bai, Yanxin Cui, Qibin Liao, Hongyang Yi, Zhonghui Liao, Gengwei Zhang, Fenfang Wu, Hongzhou Lu

“…These results support the potential of Fc domain chimeric antigens as a strategy to enhance the efficacy of subunit vaccines targeting the MPXV.…”
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Continuous detection of Chikungunya Virus in a passive surveillance system in southern Thailand, 2012-2019. by Aaron Farmer, Kathryn B Anderson, Darunee Buddhari, Thanaporn Hortiwakul, Boonsri Charernmak, Butsaya Thaisomboonsuk, Tippa Wongstitwilairoong, Taweewun Hunsawong, Chonticha Klungthong, Piyawan Chinnawirotpisan, Sarunyou Chusri, Stefan Fernandez

“…Chikungunya virus (CHIKV) infections are distributed across the globe, causing significant and, often, lasting morbidity. CHIKV vaccines are in development, but their evaluation is limited by the unpredictability of CHIKV transmission, which classically manifests as explosive epidemics separated by variable interepidemic periods. …”
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