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2541
Research Note: Establishment of vector system harboring duck RNA polymerase I promoter for avian influenza virus
Published 2025-01-01“…Reverse genetics (RG) systems are extensively utilized to investigate the characteristics of influenza viruses and develop vaccines, predominantly relying on human RNA polymerase I (pol I). …”
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2542
Risk and Prevention of Meningococcal Disease among Education Workers: A Review
Published 2004-01-01“…Immunization of education workers at the beginning of their employment, using serogroup C glycoconjugate vaccine or a combined A, C, W-135, and Y conjugate vaccine (still under development), could reduce IMD risk, but the cost effectiveness of this measure should be evaluated. …”
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2543
Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma
Published 2018-01-01“…Secondly, bone marrow-derived DCs were infected by Ad-AAH-IRES2-EGFP to yield AAH-DC vaccines. Matured DCs were demonstrated by increased expression of CD11c, CD80, and MHC-II costimulatory molecules. …”
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2544
Optimizing a low-temperature preservation technique for Bacillus anthracis strains
Published 2023-06-01“…The currently used anthrax vaccines are produced using various strains of Bacillus anthracis. …”
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2545
Challenges faced by community health volunteers in offering sexual and reproductive health care services to young women during the COVID-19 pandemic in Khwisero and Nairobi in Keny...
Published 2025-01-01“…The challenges included distrust by the community as a result of the interaction between anti-COVID-19 measures and other past and present health interventions such as vaccines for other diseases, insufficient personal protective gear and equipment (PPEs), limited human and financial resources to address community needs, limited and poor training on response to misinformation that led to vaccine hesitancy, and mental strain from stigma and burnout.ConclusionDuring pandemics, governments should provide adequate personal protective gear and financial and human resources for CHVs' work as they deliver SRH services to the community under risky conditions. …”
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2546
Immunological efficiency of Haemophilus influenzae type b polyribosyl ribitol phosphate combined with detoxified lipooligosaccharide in a rabbit model
Published 2025-02-01“… Background and Objectives: Haemophilus influenzae type b (Hib) could cause severe life-threatening infections in children. Combine vaccines have reduced invasive diseases, but disease management is still necessary. …”
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2547
Therapeutic Endoscopic Ultrasonography: Intratumoral Injection for Pancreatic Adenocarcinoma
Published 2013-01-01“…We then describe our technique in detail, including our experience injecting the AdV-tk adenoviral vector to create an in situ vaccine effect.…”
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2548
Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.
Published 2014-04-01“…Modified vaccinia virus Ankara (MVA) is an attenuated poxvirus that has been engineered as a vaccine against infectious agents and cancers. Our goal is to understand how MVA modulates innate immunity in dendritic cells (DCs), which can provide insights to vaccine design. …”
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2549
Risk and protective factors for ASF in domestic pigs and wild boar in the EU, and mitigation measures for managing the disease in wild boar
Published 2024-12-01“…However, the development of an oral GnRH vaccine for wild boar still requires substantial additional work.…”
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2550
Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023
Published 2025-02-01“…Furthermore, continued research into vaccines and therapeutic drugs remains indispensable for augmenting public health outcomes.…”
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2551
Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies.
Published 2025-01-01“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to persist, demonstrating the risks posed by emerging infectious diseases to national security, public health, and the economy. Development of new vaccines and antibodies for emerging viral threats requires substantial resources and time, and traditional development platforms for vaccines and antibodies are often too slow to combat continuously evolving immunological escape variants, reducing their efficacy over time. …”
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2552
Attitudes of Final-Year Medical Students in Jordan Towards Volunteering During a Pandemic
Published 2025-01-01“…Around 60% of students were willing to participate in future voluntary work that does not involve patients infected with COVID-19, while 29.3% of them were willing to do so depending on the type of pandemic and the availability of vaccines. There were 86.1% of students who thought that participating in voluntary work involving infected patients during pandemics, should be optional; where 10.1% suggested that it should be compulsory if vaccines were available.Conclusion: The majority of medical students did not volunteer during the COVID 19 pandemic. …”
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2553
Calreticulin as an Adjuvant In Vivo to Promote Dendritic Cell Maturation and Enhance Antigen-Specific T Lymphocyte Responses against Melanoma
Published 2022-01-01“…Our results demonstrate that CRT/39-272 can be used as a potential new adjuvant for tumor vaccines, and this finding may be useful in tumor vaccine development.…”
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2554
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2555
Dengue severity by serotype and immune status in 19 years of pediatric clinical studies in Nicaragua.
Published 2025-01-01“…<h4>Conclusions</h4>These findings demonstrate differences in dengue severity by serotype and immune status and emphasize the critical need for a dengue vaccine with balanced effectiveness against all four serotypes, particularly as existing vaccines show variable efficacy by serotype and serostatus.…”
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2556
A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim
Published 2022-01-01“…We also extend the possibility of large-vessel vasculitis development in relation to the COVID-19 vaccine due to shared ingredients found in both the vaccine and pegfilgrastim. …”
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2557
The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020
Published 2025-01-01Get full text
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2558
Association of Major Histocompatibility Complex Polymorphism With Acute Phase Response in Broiler Chicken
Published 2024-11-01“…The antibody response to the Newcastle disease vaccine (NDV) was also measured to assess humoral mediated immunity. …”
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2559
Torovirus infection in animals: a review
Published 2023-06-01“…Despite the high activity and field effectiveness of vaccines against rotavirus and coronavirus infections and viral diarrhea, massive neonatal calf diarrheas causing significant economic losses were registered in a number of large-scale livestock farms. …”
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Impact of non-pharmacological interventions on the first wave of COVID-19 in Portugal 2020
Published 2025-02-01“…Introduction: The COVID-19 pandemic caused over 7 million global deaths. Without vaccines during the first wave, governments implemented nonpharmacological interventions (NPIs) such as lockdowns, school closures, and travel restrictions. …”
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