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Chiral polypeptide hydrogels regulating local immune microenvironment and anti-tumor immune response
Published 2025-01-01“…Abstract The impact of chirality on immune response has attracted great interest in cancer vaccine research recently. However, the study of chiral synthetic polypeptide hydrogels as cancer vaccines as well as of the impact of biomaterials themselves for antitumor immunotherapy has rarely been reported. …”
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2442
hpvPDB: An Online Proteome Reserve for Human Papillomavirus
Published 2013-12-01“…Affluent information in this reserve could be of help for researchers involved in structural virology, cancer research, drug discovery, and vaccine design.…”
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2443
Signature Prediction Modeling in Cytolethal Distending Toxin-Producing Strains
Published 2017-06-01“…In conclusion, conserved signature proteins in a wide range of pathogenic bacterial strains can potentially be used in modern vaccine-design strategies.…”
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2444
B-Lymphocytes from a Population of Children with Autism Spectrum Disorder and Their Unaffected Siblings Exhibit Hypersensitivity to Thimerosal
Published 2013-01-01“…The role of thimerosal containing vaccines in the development of autism spectrum disorder (ASD) has been an area of intense debate, as has the presence of mercury dental amalgams and fish ingestion by pregnant mothers. …”
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2445
Hamster and Murine Models of Severe Destructive Lyme Arthritis
Published 2012-01-01“…However, severe destructive Lyme arthritis can be induced by infecting irradiated hamsters or mice and immunocompetent Borrelia-vaccinated hamsters, mice, and interferon-gamma- (IFN-γ-) deficient mice with viable B. burgdorferi. …”
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2446
The Impact of Media Coverage and Curfew on the Outbreak of Coronavirus Disease 2019 Model: Stability and Bifurcation
Published 2021-01-01“…In fact, to stop the spread of COVID-19, the vaccine of the disease is needed. However, in the absence of the vaccine, people must have to obey curfew and social distancing and follow the media alert coverage rule. …”
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2447
Clinical and economic burden of varicella in pediatric patients hospitalized in four institutions in Guatemala.
Published 2025-01-01“…Varicella presents a public health challenge in Guatemala, with limited evidence regarding its impact; vaccine is currently absent from the national immunization program. …”
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2449
African swine fever: one hundred years later
Published 2022-06-01“…Evidently, it is hardly possible to expect development of anti-ASF vaccines and particularly the vaccines capable of preventing and effectively protecting against ASF epizooty according to the general understanding without addressing these issues.…”
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2450
What Is the Optimal Geometry of Dissolving Microneedle Arrays? A Literature Review
Published 2025-01-01“…The application of dissolving microneedle arrays (DMNAs) is an emerging trend in drug and vaccine delivery as an alternative for hypodermic needles or other less convenient drug administration methods. …”
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2454
Epidemic Zika virus strains from the Asian lineage induce an attenuated fetal brain pathogenicity
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2455
Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest.
Published 2025-01-01“…The experimental approach focused on monitoring antibodies to the major blood-stage P. vivax vaccine candidate, the Duffy binding protein region II (DBPII-Sal1), including a novel engineered DBPII-based vaccine targeting conserved epitopes (DEKnull-2). …”
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Perbedaan Kadar Interferon Gamma dan Interleukin-10 pada Orang Dewasa Terinfeksi Ascaris Lumbricoides dengan Tidak Terinfeksi yang Diinduksi Vaksin Bacille Calmette-Guerin
Published 2016-01-01“…It can be concluded that infect Ascaris lumbricoides can pressure IFN-y production on given BCG vaccine. </em></p><p><strong><em>Keywords:</em></strong><em> Ascaris lumbricoides, BCG vaccine, Interfereon gamma (IFN-γ), Interleukin 10 (IL-10)</em></p>…”
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2458
Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
Published 2024-12-01“…The results support the use of ECL-based vaccines and suggest that loop-specific antibodies promote spirochete clearance via Fc receptor-independent as well as Fc receptor-dependent mechanisms.…”
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2459
Pathogenicity and Whole Genome Sequence Analysis of a Pseudorabies Virus Strain FJ-2012 Isolated from Fujian, Southern China
Published 2017-01-01“…The genome of FJ-2012 could be used as a reference to study the evolution of pseudorabies viruses, which is critical to the vaccine development of new emerging pseudorabies viruses.…”
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2460
Interplay of swine acute diarrhoea syndrome coronavirus and the host intrinsic and innate immunity
Published 2025-01-01“…To date, there are no vaccines and drugs approved to prevent or treat SADS-CoV infection. …”
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