Exosomes, their sources, and possible uses in cancer therapy in the era of personalized medicine by Tomas Zemanek, Lubos Danisovic, Andreas Nicodemou

“…Their potential as anticancer vaccines arise from the capacity to carry antigens and major histocompatibility complex (MHC) molecules. …”
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Unveiling the Molecular Architecture of HBV Spherical Subviral Particles: Structure, Symmetry, and Lipid Dynamics by Sonal Garg, Alyssa Ochetto, Jianming Hu, Joseph Che-Yen Wang

“…Subviral particles (SVPs) containing HBsAg are highly immunogenic, non-infectious entities that have not only revolutionized vaccine development but also provided critical insights into HBV immune evasion and viral assembly. …”
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EVALUATION OF SUITABILITY OF METHODS FOR TESTING BLOOD PROTEIN HYDROLYSATES FOR THEIR BIOLOGICAL ACTIVITY AND TOXICITY by M. N. Guseva, M. I. Doronin, M. A. Shevchenko, D. V. Mikhalishin, A. A. Shishkova

“…We used suspended baby hamster kidney (ВНК-21) cell line as a model for testing blood protein hydrolysates in the raw materials intended for FMD vaccine production for their biological activity and toxicity. …”
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Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections by Aziz Alami Chentoufi, Lbachir BenMohamed

“…The progress and limitations in developing a safe and efficient mucosal herpes vaccine are discussed.…”
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Compartmental Models Driven by Renewal Processes: Survival Analysis and Applications to SVIS Epidemic Models by Divine Wanduku, Md Mahmud Hasan

“…Applications are provided for the SVIS (Susceptible-Vaccinated-Infected-Susceptible) disease epidemic model to investigate the impacts of hazard rate functions (HRFs) on disease control. …”
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Comparison of β-Propiolactone and Formalin Inactivation on Antigenicity and Immune Response of West Nile Virus by Pritom Chowdhury, Rashmee Topno, Siraj A. Khan, Jagadish Mahanta

“…Till now there are no approved vaccines against WNV for human use. In this study, the effect of two alkylating agents, formaldehyde and β-PL, generally used for inactivated vaccine preparation, was assessed on the basis of antigenic and immunogenic potential of the inactivated WNV. …”
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Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants by Susana Martiñón, Angel Cisneros, Sergio Villicaña, Ricardo Hernández-Miramontes, Edgar Mixcoha, Psyché Calderón-Vargas

“…Adjuvants are a diverse family of substances whose main objective is to increase the strength, quality, and duration of the immune response caused by vaccines. The most commonly used adjuvants are aluminum-based, oil-water emulsion, and bacterial-origin adjuvants. …”
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Assessment of infectious diseases in commercial frozen semen straws of water buffalo bulls. Preliminary results by Rosaura Pérez-Gil

“…The animals from farms A, B, C, E and F were vaccinated against IBR and BVDV; farms D, and G did not vaccinate against these diseases. …”
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A literature review of recent advances in gastric cancer treatment: exploring the cross-talk between targeted therapies by Reza Panahizadeh, Padideh Panahi, Vahid Asghariazar, Shima Makaremi, Ghasem Noorkhajavi, Elham Safarzadeh

“…Main body This review examines over 160 clinical studies conducted globally, focusing on the effectiveness of various immunotherapy modalities, including cancer vaccines, adoptive cell therapy, immune checkpoint inhibitors (ICIs), and monoclonal antibodies (mAbs). …”
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Development of a Highly Biocompatible Antituberculosis Nanodelivery Formulation Based on Para-Aminosalicylic Acid—Zinc Layered Hydroxide Nanocomposites by Bullo Saifullah, Palanisamy Arulselvan, Mohamed Ezzat El Zowalaty, Sharida Fakurazi, Thomas J. Webster, Benjamin Geilich, Mohd Zobir Hussein

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Excess mortality across countries in the Western World since the COVID-19 pandemic: ‘Our World in Data’ estimates of January 2020 to December 2022 by Gertjan Kaspers, Saskia Mostert, Marcel Hoogland, Minke Huibers

“…In 2022, when most containment measures were lifted and COVID-19 vaccines were continued, preliminary data present 808 392 excess deaths (P-score 8.8%).Conclusions Excess mortality has remained high in the Western World for three consecutive years, despite the implementation of containment measures and COVID-19 vaccines. …”
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Predicting the infecting dengue serotype from antibody titre data using machine learning. by Bethan Cracknell Daniels, Darunee Buddhari, Taweewun Hunsawong, Sopon Iamsirithaworn, Aaron R Farmer, Derek A T Cummings, Kathryn B Anderson, Ilaria Dorigatti

“…The development of a safe and efficacious vaccine that provides immunity against all four dengue virus serotypes is a priority, and a significant challenge for vaccine development has been defining and measuring serotype-specific outcomes and correlates of protection. …”
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A data-driven approach to study temporal characteristics of COVID-19 infection and death Time Series for twelve countries across six continents by Sabyasachi Guharay

“…This time span is partitioned into three windows: (1) pre-vaccine, (2) post-vaccine and pre-omicron (BA.1 variant), and (3) post-vaccine including post-omicron variant. …”
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ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

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Perbedaan Kadar Interferon Gamma dan Interleukin-10 pada Orang Dewasa Terinfeksi Ascaris Lumbricoides dengan Tidak Terinfeksi yang Diinduksi Vaksin Bacille Calmette-Guerin by weni Mulyani, Nuzulia Irawati, Netti Suharti

“…It can be concluded that Ascaris lumbricoides infection can pressure IFN-y production on given BCG vaccine. </p><p>Keywords: ascaris lumbricoides, BCG vaccine, interferon gamma (IFN-γ), Interleukin 10 (IL-10)<br /><br /><br /><br /></p>…”
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Cardiac Device Infection due to Streptococcus pneumoniae by Theresa T Liu, Pablo B Nery, David Birnie, Peter Jessamine, Kathryn N Suh

“…A case involving Streptococcus pneumoniae CDI, which is rare, potentially vaccine preventable and may not be associated with overt antecedent pneumococcal infection, is reported.…”
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Assessing the effect of beta-propiolactone inactivation on the antigenicity and immunogenicity of cluster 2.1 duck Tembusu virus by Kanana Rungprasert, Wikanda Tunterek, Phornphisut Areeraksakul, Duangduean Prakairungnamthip, Chalida Sri-in, Navapon Techakriengkrai, Wijit Banlunara, Christine A. Jansen, Teerawut Nedumpun, Aunyaratana Thontiravong

“…Therefore, developing vaccines based on virus clusters specific to regions is essential. …”
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3-year experience of hyperthermic intravesical chemotherapy use in patients with high risk non-muscular-invasive bladder cancer by R.S. Chystiakov, F.I. Kostyev, O.V. Bondar, V.V. Lysenko, V.O. Varbanets

“…Cur   rently, the search for additional organ-sparing methods of intravesical therapy for non-muscular-invasive bladder cancer (NMIBC) is actively continuing, which could become an effective alternative to standard treatment using the Bacillus Calmette-Guérin (BCG) vaccine. The aim of this work was to analyze the safety profile and long-term results of treatment of patients with the high-risk non-muscular-invasive bladder cancer who received adjuvant intravesical chemotherapy using the Combat BRS HIVEC® device for local hyperthermia (HIVEC® therapy group; n=53) in comparison with patients who received adjuvant therapy after transurethral resection of bladder performed with the Bacillus Calmette-Guérin vaccine (BCG therapy group; n=54). …”
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<i>In vitro</i> and <i>in vivo</i> tropism and biodistribution of recombinant simian adenovirus type 25 by Irina V. Vavilova, Tatiana A. Ozharovskaia, Olga V. Zubkova, Olga Popova, Daria V. Voronina, Polina P. Goldovskaya, Denis I. Zrelkin, Alina Sh. Dzharullaeva, Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Denis Yu. Logunov, Alexander L. Gintsburg

“…Recombinant adenoviruses are widely used in the development of vaccines for a variety of infectious diseases. Despite numerous clinical studies, only a few types of human (types 5 and 26) and simian (isolate Y25) adenoviruses are currently used to produce vaccine formulations. …”
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Modeling shrimp biomass and viral infection for production of biological countermeasures by H. Thomas Banks, V. A. Bokil, Shuhua Hu, A. K. Dhar, R. A. Bullis, C. L. Browdy, F.C.T. Allnutt

“…Wecouple equations for biomass production with those for vaccine production inshrimp that have been infected with a recombinant viral vector expressing aforeign antigen. …”
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