Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy by Fermín E. González, Alexey Chernobrovkin, Cristián Pereda, Tamara García-Salum, Andrés Tittarelli, Mercedes N. López, Flavio Salazar-Onfray, Roman A. Zubarev

“…During the last decade, we demonstrated that vaccination of advanced melanoma patients with autologous tumor antigen presenting cells (TAPCells) loaded with an allogeneic heat shock- (HS-) conditioned melanoma cell-derived lysate (called TRIMEL) is able to induce an antitumor immune response associated with a prolonged patient survival. …”
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Heterogeneity of avian infectious bronchitis virus population by Ye. V. Ovchinnikova, L. O. Scherbakova, S. N. Kolosov, A. N. Andriyasova, N. G. Zinyakov, Z. B. Nikonova, A. A. Kozlov, P. B. Akshalova, D. A. Altunin, D. B. Andreychuk

“…This is facilitated by widespread use of live vaccines, simultaneous circulation of field viruses belonging to different serotypes in one flock and rapid spread of the virus. …”
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Qualitative evaluation of the implementation and national roll-out of the NHS App in England by Claire Reidy, Chrysanthi Papoutsi, Sukriti KC, Bernard Gudgin, Anthony A. Laverty, Felix Greaves, John Powell

“…Abstract Background The NHS App launched in 2019 as the ‘digital front door’ to the National Health Service in England with core features including General Practitioner (GP) appointment booking, repeat prescriptions, patient access to records and, later on, COVID-19 vaccination certification. Similar patient portals have been adopted in different formats and with variable levels of success. …”
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TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets by Trudy Straetemans, Mandy van Brakel, Sabine van Steenbergen, Marieke Broertjes, Joost Drexhage, Joost Hegmans, Bart N. Lambrecht, Cor Lamers, Pierre van Der Bruggen, Pierre G. Coulie, Reno Debets

“…We molecularly characterized TCRαβ genes of an MC2/A2-specific CD8 and MA3/DP4-specific CD4 T-cell clone derived from melanoma patients who responded clinically to MAGE vaccination. We identified MC2/A2 and MA3/DP4-specific TCR-Vα3/Vβ28 and TCR-Vα38/Vβ2 chains and validated these TCRs in vitro upon gene transfer into primary human T cells. …”
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12 Weeks of Combined Endurance and Resistance Training Reduces Innate Markers of Inflammation in a Randomized Controlled Clinical Trial in Patients with Multiple Sclerosis by Nathalie Deckx, Inez Wens, Amber H. Nuyts, Niel Hens, Benedicte Y. De Winter, Gudrun Koppen, Herman Goossens, Pierre Van Damme, Zwi N. Berneman, Bert O. Eijnde, Nathalie Cools

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Community case study: an academia-industry-government partnership that monitors and predicts outbreaks in Tri-County Detroit area since 2017 by Irene Xagoraraki, Liang Zhao, Yabing Li, Brijen Miyani, John Norton, James Broz, Andrew Kaye, Anna Mehrotra, Anil Gosine, Scott Withington, Stacey McFarlane, Russell A. Faust

“…The results of our surveillance efforts are used to assist local health departments in their understanding and response efforts for health issues in the TCDA, facilitating public health messaging for local awareness, targeted clinical testing, and increased vaccination efforts. Our data are available to the local health departments, and our methodological advancements are published and have been used by other communities nationwide and beyond. …”
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Risk factors associated with human Mpox infection: a systematic review and meta-analysis by Nicola Luigi Bragazzi, Jianhong Wu, Jude Dzevela Kong, James Orbinski, Chigozie Louisa Jane Ugwu, Ali Asgary, Woldegebriel Assefa Woldegerima

“…Conversely, smallpox vaccination was associated with a significantly reduced risk of Mpox infection (OR=0.24, 95% CI 0.11, 0.55).Conclusion Identification of risk factors associated with Mpox provides insights for strategic public health planning, enabling targeted interventions for high-risk groups and optimising resource allocation to strengthen Mpox control efforts.…”
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Camel milk is a neglected source of brucellosis among rural Arab communities by Peter Holloway, Matthew Gibson, Tanja Holloway, Iain Pickett, Brittany Crook, Jacqueline M. Cardwell, Stephen Nash, Imadidden Musallam, Bilal Al-Omari, Ahmad Al-Majali, Wail Hayajneh, Ehab Abu-Basha, Punam Mangtani, Javier Guitian

“…Control is largely via vaccination of small ruminant and cattle populations. …”
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Epidemiology and response to the COVID-19 pandemic in the Dadaab Refugee Camp Complex, Kenya, March 2020–December 2022 by Maurice Ope, Raymond Musyoka, Abdihakim Kosar, Mohammed Osman, Abdijamal Hassan, Hussein Mohammed, Penina Munyua, Bonventure Juma, Elizabeth Hunsperger, Sofia Mohammed, John Burton, Rachel B. Eidex

“…Testing capacity was bolstered, quarantine and isolation facilities established, and vaccination initiated. Conclusions: Despite a low AR and UNHCR's swift and comprehensive response, refugees' CFR was high, underscoring their vulnerability and need for targeted interventions during epidemic responses.…”
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GK-1 Improves the Immune Response Induced by Bone Marrow Dendritic Cells Loaded with MAGE-AX in Mice with Melanoma by Gabriela Piñón-Zárate, Miguel Ángel Herrera-Enríquez, Beatriz Hernández-Téllez, Katia Jarquín-Yáñez, Andrés Eliú Castell-Rodríguez

“…The aim of dendritic cell (DC) vaccination in cancer is to induce tumor-specific effector T cells that may reduce and control tumor mass. …”
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Impact of biological sex and gender-related factors on public engagement in protective health behaviours during the COVID-19 pandemic: cross-sectional analyses from a global survey by Simon L Bacon, Kim L Lavoie, Valeria Raparelli, Louise Pilote, Rubee Dev, Colleen M Norris

“…These findings may inform public health and vaccination policies in current as well as future pandemics.…”
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Virus-inspired biogenic delivery system for advancing cancer therapy by Di Sun, Hao Liang, Qianwen Mu, Chengchao Chu, Gang Liu, Chao Liu

“…Virus-inspired particles have been utilized in various applications, including vaccination, gene therapy, drug therapy, and diagnostics. …”
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Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade by Junjie Li, Yuandong Luo, Quanlan Fu, Shuxian Tang, Pingping Zhang, Ian H. Frazer, Xiaosong Liu, Tianfang Wang, Guoying Ni

“…Abstract Previously, we demonstrated that natural host-defence peptide caerin 1.1/caerin 1.9 (F1/F3) increases the efficacy of anti-PD-1 and therapeutic vaccine, in a HPV16 + TC-1 tumour model, but the anti-tumor mechanism of F1/F3 is still unclear. …”
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Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors by Saima Rashid, Abdul Bariq, Ilyas Ali, Sobia Sultana, Ayesha Siddiqa, Sayed K. Elagan

“…The main challenge is accurately estimating the virus’s rate of transmission and assessing the effectiveness of vaccination campaigns. By taking into account the modified Atangana–Baleanu–Caputo (mABC) fractional difference operator, we develop an analytical framework for an outbreak caused by MPXV and broaden it to accommodate the fractional scenario. …”
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Connective tissue disease-associated interstitial lung disease – A multicenter observational study from India by Sham Santhanam, Pravin Patil, Mohit Goyal, C B Mithun, Parthajit Das, Kavitha Mohanasundaram, Neeraj Jain, Vijaya Prasanna, Keerthi Talari, Himanshu Pathak, Parshant Aggarwal, Deepika Ponnuru, Vikram Raj Jain, Sharath Kumar

“…Only 36 (5.8%) of the 620 patients were vaccinated with influenza as well as both the conjugate and the polysaccharide pneumococcal vaccines. …”
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Investigating the relationship between the immune response and the severity of COVID-19: a large-cohort retrospective study by Riccardo Giuseppe Margiotta, Emanuela Sozio, Fabio Del Ben, Fabio Del Ben, Antonio Paolo Beltrami, Antonio Paolo Beltrami, Daniela Cesselli, Daniela Cesselli, Marco Comar, Alessandra Devito, Martina Fabris, Martina Fabris, Francesco Curcio, Francesco Curcio, Carlo Tascini, Carlo Tascini, Guido Sanguinetti

“…Overall, our study sheds light on the immuno-inflammatory aspects observed in COVID-19 patients prior to vaccination, providing insights for guiding the clinical management of first-time infections by a novel virus.…”
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Sexually transmitted diseases and immunology articles pushed by WeChat official accounts are of most interest to the Chinese public: A national cross-sectional study in China by Yi Li, Yinan Zhao, Ning Yao, Shuang Zhou, Beibei Jiang, Ying Xiong, Chunbei Zhou

“…Results: A total of 720 most influential articles from 76 WOAs operated by 69 CDCs were selected for analysis. “Suzhou Vaccination”, “China CDC News” and “Guangdong CDC” were the three top WOAs pushing the most quantities of popular articles. …”
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Identification of climate-sensitive disease incidences in vietnam: A longitudinal retrospective analysis of infectious disease rates between 2014 and 2022 by Cuong Quoc Hoang, Quang Phuong Huynh Nguyen, Thao Phuong Huynh Nguyen, Hieu Trung Nguyen, Linh Thuy Hoang, Giang Huong Vu, Woong-Ki Kim, Hai Duc Nguyen

“…Conclusion: These findings underscore the importance of implementing robust surveillance, prevention, and control measures by public health authorities in Can Tho. Initiatives like vaccination campaigns, vector control programs, public education on hygiene practices, and strengthening healthcare infrastructure are crucial for mitigating the spread of infectious diseases and safeguarding public health in the region.…”
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Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria by Esther Oluwakemi Oluwole, Alero Ann Roberts, Ifeoma Peace Okafor, Victoria Oluwasola Yesufu

“…Notably, 86% attended postnatal care services primarily for child vaccination. Christian religion (adjusted odds ratio (AOR): 1.810; confidence interval (CI): 0.989–3.313), self-employment status of spouses (AOR: 2.949: CI: 1.413–6.153), and household monthly income above 60,000.00 naira (AOR: 2.015; CI: 1.002–4.005) were predictors for ANC use. …”
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SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study by Yue Jin, Fei Yang, Christopher M. Rank, Stanley Letovsky, Peter Ramge, Simon Jochum

“…Abstract Introduction The use of antibody titers against SARS-CoV-2, as a method of estimating subsequent infection following infection or vaccination, is unclear. Here, we investigate whether specific levels of antibodies, as markers of adaptive immunity, can serve to estimate the risk of symptomatic SARS-CoV-2 (re-) infection. …”
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