Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran by Jafar Sadegh Tabrizi, Mondher Letaief, Hossein Mashhadi Abdolahi, Ramin Rezapour, Ahmed Alboksmaty, Mostafa Farahbakhsh

“…Most of HWs had completed the full vaccination schedule for Hepatitis B and COVID-19. Personal Protective Equipment (PPE) safety protocols were adhered by most of HWs within a healthcare facility. …”
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Development and Validation of a Bordetella pertussis Whole-Genome Screening Strategy by Ricardo da Silva Antunes, Lorenzo G. Quiambao, Aaron Sutherland, Ferran Soldevila, Sandeep Kumar Dhanda, Sandra K. Armstrong, Timothy J. Brickman, Tod Merkel, Bjoern Peters, Alessandro Sette

“…The immune response elicited by the protective whole-cell pertussis (wP) versus the less-protective acellular pertussis (aP) vaccine has been well characterized; however, important clinical problems remain unsolved, as the inability of the currently administered aP vaccine is resulting in the reemergence of clinical disease (i.e., whooping cough). …”
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Development of a diagnostic multivariable prediction model of a positive SARS-CoV-2 RT-PCR result in healthcare workers with suspected SARS-CoV-2 infection in hospital settings. by Sandra Liliana Valderrama-Beltrán, Juliana Cuervo-Rojas, Martín Rondón, Juan Sebastián Montealegre-Diaz, Juan David Vera, Samuel Martinez-Vernaza, Alejandra Bonilla, Camilo Molineros, Viviana Fierro, Atilio Moreno, Leidy Villalobos, Beatriz Ariza, Carlos Álvarez-Moreno

“…The selected variables were age, socioeconomic status, occupation, service, symptoms (fever, cough, fatigue/weakness, diarrhea, anosmia or dysgeusia), asthma, history of SARS-CoV-2, vaccination status, and population-level RT-PCR positivity. …”
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Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera by Najat Bdeir, Tatjana Lüddecke, Henrike Maaß, Stefan Schmelz, Ulfert Rand, Henning Jacobsen, Kristin Metzdorf, Upasana Kulkarni, Anne Cossmann, Metodi V. Stankov, Markus Hoffmann, Stefan Pöhlmann, Wulf Blankenfeldt, Alexandra Dopfer-Jablonka, Georg M. N. Behrens, Luka Čičin-Šain

“…BA.2.86 and its JN.1 derivative evade neutralization by serum antibodies of fully vaccinated individuals. In this study, we elucidate epitopes driving the immune escape of BA.2.86 and JN.1 via pseudovirus neutralization. …”
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Multiple gene-deletion vaccinia virus Tiantan strain against mpox by Yilong Zhu, Dapeng Li, Renshuang Zhao, Minghua Chen, Yue Li, Xia Yang, Hongyue Mao, Xiao Li, Yiquan Li, Chao Shang, Xianzhu Xia

“…Because of the safety risks and side effects of vaccination with live vaccinia virus (VACV) strain Tian Tan (VTT), we constructed two gene-deleted VTT recombinants (TTVAC7 and TTVC5). …”
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Association between male involvement during antenatal care and use of maternal health services in Mwanza City, Northwestern Tanzania: a cross-sectional study by Clara C Natai, Neema Gervas, Frybert M Sikira, Beatrice J Leyaro, Juma Mfanga, Mashavu H. Yussuf, Sia E Msuya

“…In Tanzania information is limited regarding influence of male involvement during ANC on utilisation of maternal health services.Objectives To determine the effect of male involvement during ANC on use of maternal health services in Mwanza, Tanzania.Design A cross-sectional study conducted from June to July 2019.Setting This study was conducted at seven randomly selected health facilities providing reproductive, maternal and child health (RCH) services in Mwanza City.Participants Included 430 postpartum women who delivered 1 year prior to the study and attending for RCH services (growth monitoring, vaccination, postpartum care).Outcome measures 4 or more ANC visits, skilled birth attendant (SBA) use during childbirth and postnatal care (PNC) utilisation 48 hours after delivery.Methods Interviews and observation of the women’s ANC card were used to collect data. …”
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Population Health Management to identify and characterise ongoing health need for high-risk individuals shielded from COVID-19: a cross-sectional cohort study by Adrian Pratt, Richard Wood, Charlie Kenward, Sam Creavin, Jennifer A Cooper

“…The study was performed at a time considered to be relatively early in the COVID-19 pandemic in the UK.Participants 1 013 940 individuals from 78 contributing general practices.Results Compared with the groups considered at ‘low’ and ‘moderate’ risk (ie, eligible for the annual influenza vaccination), individuals at high risk were older (median age: 68 years (IQR: 55–77 years), cf 30 years (18–44 years) and 63 years (38–73 years), respectively), with more primary care/community contacts in the previous year (median contacts: 5 (2–10), cf 0 (0–2) and 2 (0–5)) and had a higher burden of comorbidity (median Charlson Score: 4 (3–6), cf 0 (0–0) and 2 (1–4)). …”
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Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study by Abdurrazzaq Alege, Olayinka Rasheed Ibrahim, Rasheedat Mobolaji Ibraheem, Olajide Aladesua, Abubakar Sani Lugga, Yunusa Yusuf Yahaya, Abdallah Sanda, Bello Muhammed Suleiman

“…Although antitoxin and vaccination were related to outcomes, they did not predict hospitalization death.…”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…The clinical severity of different variants was assessed in relation to patient sex, age, clinical classification, and vaccination status.ResultsBetween Week 1 of 2023 and Week 11 of 2024, a total of 5,965 complete SARS-CoV-2 genome sequences were obtained, including 3,004 male (50.36%) and 2,961 female (49.64%) cases. …”
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Insights into Omicron: Genomic Characterization and Inpatient Risk Assessment at Single Tertiary Hospital in Indonesia by Turbawaty DK, Komala DR, Andriyoko B

“…A greater number of vaccinations significantly reduced this risk, emphasizing the protective role of vaccination.Keywords: SARS-CoV-2, Omicron variant, whole genome sequencing…”
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Prevalence, Antimicrobial Resistance, and Associated Factors of Streptococcus pneumoniae Colonization Rate among Old-Age Patients with Respiratory Tract Infection Attending Sheik H... by Surafel Mekuria, Ayichew Seyoum, Zerihun Ataro, Tigist Abebe, Kedir Urgessa

“…The provision of pneumococci conjugate vaccination and avoiding smoking are highly recommended for old aged in the community.…”
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Ten-year trends in clinical characteristics and outcome of children hospitalized with severe wasting or nutritional edema in Malawi (2011-2021): Declining admissions but worsened c... by Mphatso Nancy Chisala, Celine Bourdon, Emmanuel Chimwezi, Allison I Daniel, Chikondi Makwinja, Dominic Wang, Linnea Weise, Isabel Potani, Emmie Mbale, Robert J H Bandsma, Wieger P Voskuijl

“…Reporting of complete vaccination dropped by 49%, and no reduction in 'watch' antibiotic usage was detected. …”
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Incidence of suspected human rabies virus exposure and associated risk factors in Ethiopia: systematic review and meta-analysis by Mengistie Kassahun Tariku, Abebe Habtamu Belete, Daniel Tarekegn Worede, Sewnet Wongiel Misikir

“…Human rabies virus exposure prevention, such as dog vaccination, public awareness, and an epidemiological surveillance system, should be improved.…”
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Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen by Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

“…Our study suggests a temporal window soon after BCG vaccination, in which STAT1-dependent activation of long-lived resident cells in the tissue mediates localized protection.…”
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Difficulties faced by physicians from four European countries in rebutting antivaccination arguments: a cross-sectional study by Fernanda Rodrigues, Cornelia Betsch, Pierre Verger, Harriet Fisher, Philipp Schmid, Dawn Holford, Angelo Fasce, Amanda Garrison, Linda Karlsson, Frederike Taubert, Stephan Lewandowsky, Anna Soveri

“…Introduction Physicians play a critical role in encouraging their patients to get vaccinated, in part by responding to patients’ concerns about vaccines. …”
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The Expression of IL-6, TNF-α, and MCP-1 in Respiratory Viral Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease by Jingtong Zheng, Yue Shi, Lingxin Xiong, Weijie Zhang, Ying Li, Peter G. Gibson, Jodie L. Simpson, Chao Zhang, Junying Lu, Jingying Sai, Guoqiang Wang, Fang Wang

“…Additionally, VP patients were less likely to have received influenza vaccination. VP patients had a systemic inflammation response involving IL-6, TNF-α, and MCP-1 which may be due to virus-induced activation of macrophages. …”
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QSPR/QSAR study of antiviral drugs modeled as multigraphs by using TI’s and MLR method to treat COVID-19 disease by Ugasini Preetha P, M. Suresh, Fikadu Tesgera Tolasa, Ebenezer Bonyah

“…Abstract The ongoing COVID-19 pandemic continues to pose significant challenges worldwide, despite widespread vaccination. Researchers are actively exploring antiviral treatments to assess their efficacy against emerging virus variants. …”
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Clinical Outcomes of COVID-19 and Impact on Disease Course in Patients with Inflammatory Bowel Disease by Panu Wetwittayakhlang, Farah Albader, Petra A Golovics, Gustavo Drügg Hahn, Talat Bessissow, Alain Bitton, Waqqas Afif, Gary Wild, Peter L Lakatos

“…After initial infection, 61% of IBD patients received COVID-19 vaccinations. Conclusion. The prevalence of COVID-19 infection among patients with IBD was lower than that in the general population in Canada. …”
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Combination Antiretroviral Therapy for HIV in Rwandan Adults: Clinical Outcomes and Impact on Reproductive Health up to 24 Months by Brenda Asiimwe-Kateera, Nienke Veldhuijzen, Jean Paul Balinda, John Rusine, Sally Eagle, Joseph Vyankandondera, Julie Mugabekazi, Pascale Ondoa, Kimberly Boer, Anita Asiimwe, Joep Lange, Peter Reiss, Janneke van de Wijgert

“…We applaud the Rwandan government for having strengthened family planning and PMTCT services and for having introduced HPV vaccination in recent years, but additional work is needed to strengthen STI and HPV-related cancer screening and management in the HIV-positive population.…”
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Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment by A. G. Galeeva, A. R. Akhunova, K. V. Usoltsev, N. I. Khammadov, M. A. Efimova

“…Optimal PCVD prevention is known to be achieved through a set of veterinary and sanitary measures in combination with vaccination. High evolutionary virus variability facilitating new genotype and strain emergence requires development of new candidate recombinant vaccines against PCV-2 infection. …”
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