Effect of COVID-19 Lockdown on Alcohol Consumption Among the Youths in Kampala, Uganda. A Cross-Sectional Study by Namiiro AM, Audo R, Nannungi CD, Pitua I, Kiberu D, Talemwa P, Mujuni E, Lwesabula A, Ageimo P, Khaukha AZ, Kuol MJ, Egaru L, Koire M, Ssewante N

“…Amelia Margaret Namiiro,1 Ritah Audo,1 Charity Doreen Nannungi,1 Ivaan Pitua,1 Denis Kiberu,1 Peter Talemwa,1 Emanuel Mujuni,1 Alex Lwesabula,1 Paul Ageimo,1 Arnold Zephania Khaukha,1 Moses Jok Kuol,1 Lazarous Egaru,1 Malik Koire,1,2 Nelson Ssewante3 1School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda; 2Baylor College of Medicine Children’s Foundation, Kampala, Uganda; 3Child Health and Development Centre, College of Health Sciences, Makerere University, Kampala, UgandaCorrespondence: Amelia Margaret Namiiro, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda, Email amiemaggie99@gmail.comBackground: The COVID-19 pandemic led to increased loneliness, emotional stress, and idleness due to job losses and school closures which can drive substance use among vulnerable populations like youths. …”
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The Upregulation of IL-1β Induced by Cisplatin Triggers PI3K/AKT/MMP9 Pathway in Pericytes Mediating the Leakage of the Blood Labyrinth Barrier by Yu M, Jiang WJ, Yu M, Zhou Z, Wang M, Li L

“…Miao Yu,1,2,* Wen-Jun Jiang,3,4,* Meng Yu,1 Zan Zhou,1,2 Min Wang,1 Li Li1 1Department of Physiology, Medical College of Jiaxing University, Jiaxing, Zhejiang, 314000, People’s Republic of China; 2Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang, 832000, People’s Republic of China; 3The Second People’s Hospital of Li Shui, Li Shui, Zhejiang, 323000, People’s Republic of China; 4Department of Physiology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310051, People’s Republic of China*These authors contributed equally to this workCorrespondence: Min Wang, Email wangmin3826@zjxu.edu.cn Li Li, Email lily7588@163.comBackground: Blood–labyrinth barrier (BLB) damage has been recognized as a key mechanism underlying cisplatin (CDDP)-induced hearing loss. …”
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Solid Self-Microemulsifying Drug Delivery System for Improved Oral Bioavailability of Relugolix: Preparation and Evaluation by Li ZL, Deng GX, Fang CZ, Zhao YQ, Yuan J, Chen L, Zhong HJ, Guo F

“…Zi-Lin Li,1,* Guo-Xing Deng,1,* Chuan-Zhou Fang,1,* Yue-Qi Zhao,1 Jing Yuan,2 Liang Chen,3 Hai-Jun Zhong,1 Feng Guo1 1School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, 471000, People’s Republic of China; 3Jiangxi Prozin Pharmaceutical Co., LTD, Jian, 343100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Guo; Hai-JunZhong, School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China, Tel +86 0791 86361839, Email fengguo@ncu.edu.cn; zhonghj@ncu.edu.cnPurpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility and being a substrate of P-glycoprotein (P-gp). …”
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Dynamic Complement Protein Changes in Aqueous Humor and Plasma of Patients With Retinal Vein Occlusion During Ranibizumab Treatment by Guo T, Zhao Y, Liang S, Wang J, Liu H, Zhou Y, Xu H, Chen Z

“…Tingting Guo,1,2,* Yanying Zhao,2,3,* Shengnan Liang,2,3 Jie Wang,2 Hengwei Liu,2 Yufan Zhou,2 Heping Xu,3– 5 Zhongping Chen1– 3,6 1Aier Eye Hospital, Jinan University, Guangzhou, People’s Republic of China; 2Changsha Aier Eye Hospital, Changsha, People’s Republic of China; 3Aier Academy of Ophthalmology, Central South University, Changsha, People’s Republic of China; 4Aier Institute of Optometry and Vision Science, Aier Eye Hospital Group, Changsha, People’s Republic of China; 5The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK; 6School of Stomatology and Ophthalmology, Xianning Medical College, Xianning, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhongping Chen; Heping Xu, Email chenzhongping@csu.edu.cn; heping.xu@qub.ac.ukPurpose: To assess dynamic changes of complement protein in aqueous humor (AH) and plasma of retinal vein occlusion (RVO) patients during ranibizumab treatment, and to explore the differential expression of complement proteins in branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO).Patients and Methods: This prospective, consecutive case series study collected AH and plasma samples from 27 RVO patients at baseline, 1 and 2 months after ranibizumab treatment, including 19 BRVO and 8 CRVO patients. …”
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A New Nanocomposite for Inducing Demineralized Dentin Remineralization by Ban G, Long J, Yan K, Li Q, Huang X, Wei X, Xie F

“…Guifei Ban,1,2,* Jindong Long,1,2,* Kaiqi Yan,1,2,* Qiurong Li,1,2 Xiaoman Huang,1,2 Xiaolang Wei,1,2 Fangfang Xie1,2 1College & Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China; 2Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, College of Stomatology, Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, China; Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, College of Stomatology, Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fangfang Xie, Email xiedualfang@163.comObjective: This study aimed to investigate a method for promoting the remineralization of demineralized dentin collagen fibers, with the objective of enhancing the bonding strength and durability of dentin resin while reducing the incidence of secondary caries.Methods: A mineralized solution, PAMAM-COOH/ACMP-MDP ethanol solution, was prepared, consisting of the dendritic organic macromolecule PAMAM-COOH, magnesium ions, and methacryloyloxydecyl dihydrogen phosphate (MDP). …”
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Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study by Zucca G, Vigani B, Valentino C, Ruggeri M, Marchesi N, Pascale A, Giovilli G, Malavasi L, Sandri G, Rossi S

“…Gaia Zucca,1 Barbara Vigani,1 Caterina Valentino,1 Marco Ruggeri,1 Nicoletta Marchesi,1 Alessia Pascale,1 Giulia Giovilli,2 Lorenzo Malavasi,2 Giuseppina Sandri,1 Silvia Rossi1 1Department of Drug Sciences, University of Pavia, Pavia, 27100, Italy; 2Department of Chemistry and INSTM, University of Pavia, Pavia, 27100, ItalyCorrespondence: Silvia Rossi; Barbara Vigani, Department of Drug Sciences, University of Pavia, Via Taramelli 12, Pavia, 27100, Italy, Email silvia.rossi@unipv.it; barbara.vigani@unipv.itPurpose: The main purpose of the study was the formulation development of nanogels (NHs) composed of chondroitin sulfate (CS) and low molecular weight chitosan (lCH), loaded with a naringenin-β-cyclodextrin complex (NAR/β-CD), as a potential treatment for early-stage diabetic retinopathy.Methods: Different formulations of NHs were prepared by varying polymer concentration, lCH ratio, and pH and, then, characterized for particle size, zeta potential, particle concentration (particles/mL) and morphology. …”
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Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis by Zheng H, Xu S, Yang R, Jiao WE, Qiao YL, Liu JY, Fan HM, Zhou YT, Ni HF, Chen J, Deng YQ, Chen SM

“…Han Zheng,1,* Shan Xu,1,* Rui Yang,1,* Wo-Er Jiao,1 Yue-Long Qiao,1,2 Jia-Yu Liu,1 Hui-Ming Fan,1 Yan-Ting Zhou,1 Hai-Feng Ni,3 Jin Chen,1 Yu-Qin Deng,1 Shi-Ming Chen1 1Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; 3Department of Otolaryngology-Head and Neck Surgery, Zhejiang Hospital, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu-Qin Deng; Shi-Ming Chen, Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, Email bamboo0723@126.com; shimingchen0468@163.comBackground: The role of memory B cells and their subgroups in allergic rhinitis (AR) and allergen immunotherapy (AIT) remains unclear. …”
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Correlation Between Inflammatory Markers and Pathogenic Bacteria in Children’s Winter Respiratory Infections in Xinjiang by Wang L, Wang W, Wang J, Zhu L, Luo J

“…Lixia Wang,1,* Wei Wang,2,* Jian Wang,1 Ling Zhu,1 Jianjiang Luo1 1Department of Respiratory and Critical Care Medical Department Infectious Diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianjiang Luo, Department of Respiratory and Critical Care Medical Department infectious diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, No. 116 Huanghe Road, Shayibake District, Urumqi, Xinjiang, People’s Republic of China, Tel +86013999946655, Email ljj.781201@163.comBackground: This study examines the distribution characteristics of pathogenic bacteria in respiratory infections and their relationship with inflammatory markers to guide clinical drug use.Methods: We selected 120 patients with lower respiratory tract infection in the electronic medical record system of Xinjiang Provincial People’s Hospital from March 2019 to March 2023 for a case-control study. …”
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Early Mobilization in Post-Orthopedic Surgery Patients: A Scoping Review by Rhamelani P, Mahdhiya NZ, Yoviana I, Jessica J, Komariah M

“…Putri Rhamelani,1 Naifa Zahra Mahdhiya,1 Istiani Yoviana,1 Jessica Jessica,1 Maria Komariah2 1Nursing Professional Study Program, Faculty of Nursing, Padjadjaran University, Sumedang, West Java, Indonesia; 2Department of Fundamental Nursing, Faculty of Nursing, Padjadjaran University, Sumedang, West Java, IndonesiaCorrespondence: Putri Rhamelani, Nursing Professional Study Program, Faculty of Nursing, Padjadjaran University, Sumedang, West Java, Indonesia, Tel +628882255466, Email putri19016@mail.unpad.ac.idAbstract: Post-orthopedic surgery patients need to undergo a recovery process with immobilization to minimize pain or swelling. …”
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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…Qiao Wang,1,* Xin Luo,1,* Yuwen Su,1 Yi Jin,1 Qiqi Kuang,1 Siying Li,1 Weiyun Shen,2 Yanshan Zhu1 1Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Anesthesiology, Second Xiangya Hospital, Anesthesiology Research Institute of Central South University, Changsha, Hunan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Luo; Yanshan Zhu, Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, 139 Renmin Middle Road, Changsha, Hunan, People’s Republic of China, Email 248201037@csu.edu.cn; 218202091@csu.edu.cnBackground: Psoriasis is an immune-related inflammatory systemic condition characterized by dysregulated keratinocyte proliferation and chronic inflammation. …”
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Association of Depression with Age at Natural Menopause: A Cross-Sectional Analysis with NHANES Data by An S, Ren S, Ma J, Zhang Y

“…Shuaiqi An,1,* Shiyan Ren,1,* Jiawen Ma,1 Yizhou Zhang1,2 1School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Zhejiang Famous Chinese Medicine Clinic, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yizhou Zhang, School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China, Email zhangyizhou2005@126.comPurpose: To evaluate the association between depression and age of natural menopause in American women.Patients and Methods: This cross-sectional study utilized eight cycles of the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2023. …”
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Osteoarthritis and Degree of Fatigue are Associated with Pain Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study of 394 Patients by Wang Z, Lan T, Zhang Y, Guo Z, Yu H, Sun G, Wang Z, Yan Z, Tao Q, Xu Y

“…Zihan Wang,1,2,* Tianyi Lan,1,2,* Yuqiao Zhang,1,2 Zijia Guo,3 Hongwei Yu,4 Guiyao Sun,5 Zhitian Wang,6 Zeran Yan,1 Qingwen Tao,1 Yuan Xu1 1Traditional Chinese Medicine Department of Rheumatism, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Graduate School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Graduate School, Inner Mongolia Medical University, Hohhot, People’s Republic of China; 4Department of Radiology, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 5Department of Orthopedics, Shuangqiao Hospital, Beijing, People’s Republic of China; 6Science Faculty, University of Auckland, Auckland, New Zealand*These authors contributed equally to this workCorrespondence: Qingwen Tao; Yuan Xu, Email taoqg1@sina.com; xuyuan2004020@163.comObjective: To observe how osteoarthritis (OA) and degree of fatigue affect are associated with pain levels in patients with fibromyalgia syndrome (FMS).Methods: A cross-sectional study was conducted involving FMS patients. …”
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Community Integration of Disability: A Bibliometric and Knowledge-Map Analysis by Wang S, Li D, Liu C, Sun X, Shi Y, Wang H, Zhang H

“…Shuaiyou Wang,1 Dingding Li,1 Chenjun Liu,1 Xueting Sun,1 Yage Shi,1 Hongru Wang,2 Huimin Zhang3 1School of Nursing, Xinxiang Medical University, Xinxiang, Henan, People’s Republic of China; 2Nursing of Department, Xinxiang First People’s Hospital, Xinxiang, Henan, People’s Republic of China; 3School of Nursing, Ningxia Medical University, Yinchuan, People’s Republic of ChinaCorrespondence: Huimin Zhang, School of Nursing, Ningxia Medical University, No.1160 Shengli South Street, Xingqing District, Yinchuan, 750001, People’s Republic of China, Email 35290915@qq.comBackground: Community integration (CI) is the ultimate goal of rehabilitation for individuals with disabilities. …”
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Gambaran Golongan Sekretor dan Nonsekretor yang Diperiksa Melalui Saliva Mahasiswa Pendidikan Dokter Fakultas Kedokteran Universitas Andalas by Alqadri ., Zelly Dia Rofinda, Rika Susanti

“…The population were 54 students Medical Faculty of Andalas University which choosen by simple random sampling. …”
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Ações de conscientização sobre uso de repelentes e formas de combate ao mosquito Aedes aegypti by Denise de Abreu Garófalo, Anna Luiza Behling Pinto Chize, Luiz Eduardo Fileto Caldeira, Dalila dos Santos Cerqueira Pinto, Luciana Betzler de Oliveira de Siqueira, Ana Paula dos Santos Matos, Bárbara da Silva e Souza Lorca, Zaida Maria Faria de Freitas, Eduardo Ricci Júnior

“…The initiatives promoted interaction between pharmacists, students, and the community, reinforcing the importance of actions that bring the university and society closer together. Therefore, others shall be carried out to spread information about these diseases. …”
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A Decision-Making Approach for Ranking Tertiary Institutions’ Service Quality Using Fuzzy MCDM and Extended HiEdQUAL Model by Olufunke Oladipupo, Taiwo Amoo, Olawande Daramola

“…This study adopted a contextualized service quality model for educational domain called HiEdQUAL with some extended criteria in order to evaluate the perception of service quality by respondents from the selected higher institutions: two private universities and two public universities from the south-west region of Nigeria. …”
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Coexistence of Asymptomatic Allergic Bronchopulmonary Aspergillosis and Active Pulmonary Tuberculosis: Case Report by Jia Q, Wang L, Tong X, Sun J, Fan H

“…Qingqing Jia,1,2,* Lian Wang,1,2,* Xiang Tong,1,2 Jibo Sun,1,2 Hong Fan1,2 1Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2State Key Laboratory of Respiratory Health and Multimorbidity, Sichuan University, Chengdu, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Fan, Email fanhong@scu.edu.cnAbstract: We present a rare case of asymptomatic allergic bronchopulmonary aspergillosis (ABPA) concurrent with active pulmonary tuberculosis. …”
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Isotretinoin – Induced AGEP: A Case Report by Alotaibi HM, AlNasser S, Aldossari A, Alluhaybi A, Alsergani R, Alrajban W

“…Hend M Alotaibi,1 Sultan AlNasser,1 Abdulelah Aldossari,2 Abdulrahman Alluhaybi,1 Reem Alsergani,1 Waleed Alrajban1 1Department of Dermatology, College of Medicine, King Saud University and King Saud University Medical City (KSUMC), Riyadh, Saudi Arabia; 2Department of Dermatology, King Fahad Specialist Hospital, Buraydah, Saudi ArabiaCorrespondence: Sultan AlNasser, Email SultanAlNasser70@gmail.comAbstract: Acute Generalized Exanthematous Pustulosis (AGEP) is a relatively rare but severe dermatological adverse reaction characterized by the rapid onset of generalized erythema, coupled with numerous sterile nonfollicular pustules. …”
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Artificial intelligence as a factor revolutionizing higher education by Yu. B. Melnyk, I. S. Pypenko

“…The total number of respondents from 57 countries was 788, of whom 363 were students and 425 were university faculty. The probability sampling method was applied. …”
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Adverse Events of the BCG (Bacillus Calmette–Guérin) and Rotavirus Vaccines in a Young Infant with Inborn Error of Immunity by Suleiman Al-Hammadi, Najla S. Alkuwaiti, Ghassan A. Ghatasheh, Huda Al Dhanhani, Hiba M. Shendi, Abdulghani S. Elomami, Farida Almarzooqi, Abdul-Kader Souid

“…International registries of adverse events of universally administered vaccines are crucial.…”
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