Puerarin Ameliorates the Ferroptosis in Diabetic Liver Injure Through the JAK2/STAT3 Pathway Inhibition Based on Network Pharmacology and Experimental Validation by Fan X, Liu S, Yu J, Hua J, Feng Y, Wang Z, Shen Y, Lan W, Wang J

“…Xiaoxu Fan,1 Shuangqiao Liu,1 Jing Yu,2 Jian Hua,1 Yingtong Feng,1 Zhen Wang,1 Yiwei Shen,1 Wei Lan,2 Jingxia Wang1 1School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2School of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi, People’s Republic of ChinaCorrespondence: Jingxia Wang, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, People’s Republic of China, Email 601435@bucm.edu.cn Wei Lan, School of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi, People’s Republic of China, Email lanwei516@sina.comBackground: Diabetic liver injury (DLI) is a common complication of diabetes mellitus (DM), which seriously endangers the health of diabetic patients. …”
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Remote Continuous Microinjury-Triggered Cytokines Facilitate Severe Diabetic Foot Ulcer Healing via the Ras/Raf/MEK/ERK Pathway by Huang X, Liu J, Wu X, Mo Y, Luo X, Yang Y, Yang C, Liang X, Liang R, Chen Y, Fan Z, Lu W, Chen Y, Hua Q

“…Xiajie Huang,1,2,* Jie Liu,1,* Xiaomei Wu,1 Yangzhou Mo,1 Xiping Luo,1 Yongge Yang,1 Chaoquan Yang,1 Xinyun Liang,1 Rongyuan Liang,1 Yeping Chen,1 Zezhen Fan,1 William Lu,3 Yan Chen,1 Qikai Hua1 1Department of Bone and Joint Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China; 2Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-Constructed by the Province and Ministry, Guangxi Medical University, Nanning, People’s Republic of China; 3Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan Chen; Qikai Hua, Department of Bone and Joint Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China, Email cy003@connect.hku.hk; hqk100@yeah.netPurpose: Microinjury can trigger in situ tissue repair. …”
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Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology by Zhang KX, Zhang JW, Jiang YH, Wang YR, Liu ZL, Ding PL, Wang XY, Cui WQ, Xu XQ, Wang YH

“…Kai-Xin Zhang,1 Ji-Wei Zhang,2 Yan-Hong Jiang,1 Yi-Ran Wang,1 Zhen-Ling Liu,1 Peng-Li Ding,1 Xiang-Ying Wang,1 Wen-Qiang Cui,3 Xiang-Qing Xu,3,* Ya-Han Wang3,* 1First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2College of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 3Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiang-Qing Xu, Ya-Han Wang; Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China, Email happyxiangqing@163.com; sdwangyahan@sina.comBackground: Danggui-Shaoyao-San (DSS) is a traditional Chinese medicine prescription with a history of nearly 2000 years, originally widely used for gynecological diseases, and in recent years research has found that DSS also has a good therapeutic effect on Alzheimer’s disease (AD).Purpose: The objective is to investigate the metabolic components of the DSS in the blood and the potential mechanisms for AD.Materials and Methods: Liquid chromatography‒mass spectrometry (LC-MS) combined with gas chromatography‒mass spectrometry (GC-MS) based non-targeted metabolomics were used to conduct in-depth research. …”
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Highly Stable Antitumor Silver-Lipid Nanoparticles Optimized for Targeted Therapy by Darwish A, Sándor N, Szenti I, Marosvölgyi T, Juhász K, Rónavári A, Kachal E, Kutus B, Kónya Z, Balogi Z

“…Ammar Darwish,1 Nikolett Sándor,1 Imre Szenti,2 Tamás Marosvölgyi,3 Kata Juhász,1 Andrea Rónavári,2 Edi Kachal,2 Bence Kutus,4 Zoltán Kónya,2 Zsolt Balogi1 1Institute of Biochemistry and Medical Chemistry, Medical School, University of Pécs, Pécs, H-7624, Hungary; 2Department of Applied and Environmental Chemistry, University of Szeged, Szeged, H-6720, Hungary; 3Institute of Bioanalysis, Medical School, University of Pécs, Pécs, H-7624, Hungary; 4Department of Molecular and Analytical Chemistry, University of Szeged, Szeged, H-6720, HungaryCorrespondence: Zsolt Balogi, Email zsolt.balogi@aok.pte.huBackground: Silver nanoparticles (AgNPs) have a broad spectrum of biocidal effects, allowing also their antitumor application. …”
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Evaluation of the Effectiveness of Standard Precaution Training on Disposition of Occupational Blood Exposure Among Healthcare Trainees: A Pre-Post Intervention Study by Zhang X, Li H, Li N, Li Y, Kong L, Zhang M, Wang P, Ma Y, Ni L, Liu L, Meng X

“…Xing Zhang,1 Hongwei Li,2 Ning Li,1 Yusen Li,1 Li Kong,1 Min Zhang,1 Peng Wang,1 Yonghui Ma,1 Leiping Ni,2 Lili Liu,1 Xiujuan Meng1 1Healthcare-Associated Infection Control Department, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of China; 2Medical Education Center, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of ChinaCorrespondence: Xiujuan Meng, Healthcare-associated infection control department, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of China, Tel +86 537 2903180, Fax +86 537 2213030, Email mxj0324@163.comIntroduction: Blood-borne occupational exposure (OBE) is one of the major public health problem for healthcare workers globally. …”
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Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…Leran Wang,1 Lei Liu,2 Huilan Luo,3– 5 Yiling Wu,3– 5 Lingyan Zhu3– 5 1Queen Mary School, Jiangxi Medical College, Nanchang University, Nanchang City, People’s Republic of China; 2Department of Endocrinology, Lu’an Hospital of Anhui Medical University, Lu’an City, Anhui Province, People’s Republic of China; 3Department of Endocrinology and Metabolism, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang City, People’s Republic of China; 4Jiangxi Clinical Research Center for Endocrine and Metabolic Disease, the First Affiliated Hospital of Nanchang University, Nanchang City, People’s Republic of China; 5Jiangxi Branch of National Clinical Research Center for Metabolic Disease, Nanchang City, People’s Republic of ChinaCorrespondence: Lingyan Zhu, Jiangxi Branch of National Clinical Research Center for Metabolic Disease, No. 17, Yongwaizheng Street, Nanchang City, Jiangxi Province, People’s Republic of China, Tel +86-13870690788, Email zly982387@126.comBackground/Objective: Considering the uncertain relationship between high-density lipoprotein cholesterol (HDL-C) and uric acid (UA) with diabetic retinopathy (DR),this study investigates the link between Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and DR in T2DM patients, evaluating its potential for DR diagnosis and early prediction.Study Design and Data Collection: This retrospective study analyzed 1450 type 2 diabetes patients, divided into NDR and DR groups by retinal exams. …”
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The Effective Compound Combination of Bufei Yishen Formula III Improves the Mitochondrial Dysfunction via Inhibiting JNK/Sab Pathway in COPD Mice by Song M, Han M, Zhang H, Yang Y, Tian Y, Li J, Zhao J

“…China, Henan University of Chinese Medicine, Zhengzhou, 450046, People’s Republic of China; 3Department of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Zhao, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengdong, Zhengzhou, Henan, 450046, People’s Republic of China, Tel +86-15100165967, Email Jiezhao1702@163.comPurpose: The effective compound combination of Bufei Yishen formula III (ECC-BYF III) has shown protective effects against chronic obstructive pulmonary disease (COPD). …”
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N-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan-Aluminum Nano-Adjuvant Elicit Strong Immune Responses in Porcine Epidemic Diarrhea Inactivated Vaccine by Jin Z, Liu J, Guo S, Xu S, Gong X, Zhang C, Zhao K

“…Zheng Jin,1 Jiali Liu,1 Sihan Guo,2 Shangen Xu,1 Xiaochen Gong,1,3 Chunjing Zhang,3 Kai Zhao1,2 1Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, Taizhou Key Laboratory of Biomedicine and Advanced Dosage Forms, School of Life Sciences, Taizhou University, Taizhou, Zhejiang, 318000, People’s Republic of China; 2Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China; Key Laboratory of Microbiology, College of Heilongjiang Province, School of Life Sciences, Heilongjiang University, Harbin, Heilongjiang, 150080, People’s Republic of China; 3School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People’s Republic of ChinaCorrespondence: Kai Zhao; Chunjing Zhang, Email zybin395@126.com; cjzhang2005@163.comBackground: Porcine epidemic diarrhea virus (PEDV) inactivated vaccine lacks an effective vaccine adjuvant as an immune activator. …”
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IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture by Moore TC, Pinkerton TS, Petro TM

“…Tyler C Moore,1 Terrence Scott Pinkerton,1 Thomas M Petro2 1Department of Biology, College of Science and Technology, Bellevue University, Bellevue, NE, 68005, USA; 2Department of Oral Biology, University of Nebraska Medical Center, Lincoln, NE, 68583, USACorrespondence: Thomas M Petro, Department of Oral Biology, University of Nebraska Medical Center, College of Dentistry, 4000 East Campus Loop South, Lincoln, NE, 68583, USA, Email tpetro@unmc.eduIntroduction: Macrophage responses to lipopolysaccharides (LPS) drive inflammatory diseases, such as periodontitis, with production of IL-6 and Nitric Oxide (NO). …”
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Exploring the relationship between mental health issues and academic performance of undergraduate students in a Ghanaian tertiary institution: a cross-sectional study by Andrew Nketsia Arthur, Joanne Fraikue, Bijoux Adu-Amankwah, Richard Ofori, Dorcas Sekyi, Abena Afrakomah Boateng, Elsie Asamoah, Seth Christopher Yaw Appiah

“…This study investigated the relationship between mental health incidence and academic performance among university students in a public university in Ghana. …”
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Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers by Pin Deng, Hongshuo Shi, Xuyue Pan, Huan Liang, Shulong Wang, Junde Wu, Wei Zhang, Fasen Huang, Xiaojie Sun, Hanjie Zhu, Zhaojun Chen

“…The USA (n=1866), England (n=606), and China (n=599) were the three largest contributors. The University of Washington had the greatest number of publications within this time period (n=103), and it had the most cooperative units and was in the core position in all research institutions, followed by the University of Manchester (n=94) and the University of Miami (n=92). …”
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El desbanque del Usted, y el uso del Tú, al rescate de la igualdad comunicativa en un entorno universitario español by María Gemma Sánchez González

“…Generally, in the teacher-student relationship in a university environment, the use of Usted is the first sign of respect and rank in the classrooms. …”
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Self-assessment of didactic performance of psychology and education professors in Mexico and Peru by Aldo Bazán-Ramírez, Walter Capa-Luque, Roberto Chávez-Nava, Mónica C. Dávila-Navarro, Homero Ango-Aguilar, Edmundo Hervias-Guerra, Catalina Bello-Vidal

“…A total of 203 teachers participated, of whom 64 were professors from a public university in northwestern Mexico, and 139 professors from two public universities in Peru.ResultsSatisfactory evidence of content-based validity was found, Aiken’s V estimates were higher than 0.70 for all items in the criteria: clarity, pertinence and relevance. …”
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Cultural adaptation, translation and validation of the conflict in adolescence dating relationship inventory (CADRI) in the Greek language. by Esperanza Barroso-Corroto, Juan Manuel Carmona-Torres, José Alberto Laredo-Aguilera, Ángel López-Fernández-Roldan, Carlos Navarrete-Tejero, Evangelia Kartsoni, Antonios Christodoulakis, Athina Patelarou, Michail Zografakis-Sfakianakis

“…Furthermore, 88.7% of university students perpetrated DV in the last year on their partners, and 90.7% suffered DV, with verbal and emotional violence the most common types.…”
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PEER TUTORING IN LEARNING A FOREIGN LANGUAGE AS A NON-MAJOR by E. A. Makarova

“…As a result the peer tutoring models have been developed and implemented within the regular classroom settings while teaching reading and translation to students in non-linguistic university. The offered models of tutoring involve preparation realities of the Russian higher education institutions; meanwhile, there are no special centers of mentoring with separate teaching staff and psychologists in foreign universities. …”
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Social determinants of student mental health before and after the Beirut port explosion: two cross-sectional studies by Julia Scheuring, Tania Bosqui

“…The aim of this study was to identify key social determinants of common mental health symptoms before and after the Beirut port explosion for students at the American University of Beirut, a university based around 4 km from the port. …”
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Systematic Analysis of E3 Ligase-Related Genes Identified UBE2L3 as a Prognostic Biomarker Associated With Drug Resistance in Acute Myeloid Leukemia by Ling C, Cao N, Wang H, Wan Y, Liang X, Guo J, Xiao M, Zhang Q, Zhai Z

“…Chun Ling,1,2 Nengneng Cao,1 Huiping Wang,1 Yang Wan,1 Xue Liang,1 Jinjing Guo,1 Meng Xiao,1 Qiguo Zhang,2 Zhimin Zhai1 1Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China; 2Department of Hematology, Affiliated Chuzhou Hospital of Anhui Medical University, First People’s Hospital of Chuzhou, Chuzhou, Anhui, 239001, People’s Republic of ChinaCorrespondence: Zhimin Zhai, Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China, Email zzzm886@163.comBackground: Acute Myeloid Leukemia (AML) is a prevalent neoplastic disorder. …”
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Metabolism-Related Adipokines and Metabolic Diseases: Their Role in Osteoarthritis by Zhang Q, Zhao YX, Li LF, Fan QQ, Huang BB, Du HZ, Li C, Li W

“…Qian Zhang,1,* Yi Xuan Zhao,1,* Long Fei Li,2 Qian Qian Fan,3 Bin Bin Huang,1 Hong Zhen Du,1 Chen Li,3 Wei Li3 1School of Special Education and Rehabilitation, Binzhou Medical University, Yantai, Shandong, People’s Republic of China; 2Cerebrovascular Disease Ward, The First People’s Hospital of Ping Ding Shan, Pingdingshan, Henan, People’s Republic of China; 3Department of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Li; Chen Li, Department of Rehabilitation Medicine Binzhou Medical University Hospital, No. 661 huanghe 2nd Road, Binzhou, Shandong, People’s Republic of China, Email yishengliwei@163.com; lc_0625@163.comAbstract: Osteoarthritis (OA) affects several joints but tends to be more prevalent in those that are weight-bearing, such as the knees, which are the most heavily loaded joints in the body. …”
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Comparing Health Care Financing in Indonesia and Thailand from 1995-2010: What Lessons Could Be Learned? by Darius Erlangga, Lizheng Shi

“…**Purpose:** In 2010, the World Health Organization (WHO) released its report about health system financing and identified universal coverage as the best way to attain the right of every human being to enjoy “the highest attainable standard of health”. …”
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Effects of Teriparatide on Bone Mineral Density and Prevention of Fragility Fractures in Saudi Arabian Subjects with Osteoporosis: A Two-Year Clinical Study from a Single Center by Mir Sadat-Ali, Abdallah Al-Omran, Khalid AlTabash, Dakheel A. AlDakheel, Salma Elansassy, Tarek Hegazi, Mona Al Muhaish

“…This study took place at King Fahd Hospital of the University, Imam AbdulRahman Bin Faisal University, Dammam, Saudi Arabia. …”
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