Cost-Benefit Analysis of Genetic Testing as a Prenatal Diagnostic Tool for Thalassemia: A Single-Center Study From Central Thailand by Malasai K, Jittikoon J, Udomsinprasert W, Talungchit P, Youngkong S, Sangroongruangsri S, Mahasirimongkol S, Chaikledkaew U

“…Both one-way and probabilistic sensitivity analyses were conducted to account for uncertainties in the parameters used.Results: The results revealed that adhering to the standard screening program with genetic testing resulted in a cost-savings of approximately 490 USD per prevented thalassemia case. …”
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Evaluation of Delay Characteristics at A 4- Legged Signalised Intersection for Improvement in The Level of Service. A Case Study of Jinja Road Intersection. by Babirye, Joanitor

“…Hence a micro- simulation model such as VISSIM was used to assess the performance, level of service of Jinja road intersection in order to minimize the uncertainties of increased; control delays, queue lengths experienced during peak hours. …”
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The MBH–M∗ Relation up to z ∼ 2 through Decomposition of COSMOS-Web NIRCam Images by Takumi S. Tanaka, John D. Silverman, Xuheng Ding, Knud Jahnke, Benny Trakhtenbrot, Erini Lambrides, Masafusa Onoue, Irham Taufik Andika, Angela Bongiorno, Andreas L. Faisst, Steven Gillman, Christopher C. Hayward, Michaela Hirschmann, Anton Koekemoer, Vasily Kokorev, Zhaoxuan Liu, Georgios E. Magdis, Alvio Renzini, Caitlin Casey, Nicole E. Drakos, Maximilien Franco, Ghassem Gozaliasl, Jeyhan Kartaltepe, Daizhong Liu, Henry Joy McCracken, Jason Rhodes, Brant Robertson, Sune Toft

“…Considering selection biases and measurement uncertainties, we find that the M _BH / M _* ratio evolves as ${\left(1+z\right)}^{0.4{8}_{-0.62}^{+0.31}}$ thus remains essentially constant or exhibits mild evolution up to z  ∼ 2.5. …”
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Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: pro... by Suzana Shahar, Kalavathy Ramasamy, Norhayati Ibrahim, Nur Nadia Mohamad Habibullah, Munirah Ismail, Mohd Zul Amin Kamaruddin, Shirley Gee Hoon Tang, Mohd Faisal Abdul Hamid

“…However, little is known regarding the efficacy of YBG at lower dosages in relation to URTI, fatigue, immune response and uncertainties of how they affect the gut microbiota composition.Methods and analysis This 12-week randomised, double-blinded, placebo control, parallel-group clinical trial aims to evaluate the efficacy of YBG 1,3/1,6 on respiratory tract infection, fatigue, immune markers and gut health among adults with moderate stress. …”
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Using satellite-based Sun-induced chlorophyll fluorescence and spectral reflectance for improving terrestrial CO2 flux estimates of India by Aparnna Ravi, Dhanyalekshmi Pillai, Christoph Gerbig, Stephen Sitch, Sönke Zaehle, Vishnu Thilakan, Chandra Sekhar Jha, Thara Anna Mathew

“…Significant uncertainties in terrestrial carbon fluxes exist in regions with limited ground-based observations, impacting our understanding of ecosystem carbon dynamics and emission reduction needs. …”
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Considerations for determining warm-water coral reef tipping points by P. Pearce-Kelly, A. H. Altieri, J. F. Bruno, C. E. Cornwall, M. McField, A. I. Muñiz-Castillo, J. Rocha, R. O. Setter, C. Sheppard, R. M. Roman-Cuesta, C. Yesson

“…A fuller assessment of interacting stressors is likely to further lower the tipping point thresholds in most cases. Uncertainties around tipping points for such crucially important ecosystems underline the imperative of robust assessment and, in the case of knowledge gaps, employing a precautionary principle favouring lower-range tipping point values.…”
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Evaluation of Elexacafor/Tezacaftor/Ivacaftor therapy after lung transplantation in Cystic Fibrosis: The Dutch National KOALA study by Johanna P. van Gemert, Bart Luijk, Merel E. Hellemons, Klara A. Visser, Carina.M.E. Hansen, Renske van der Meer, C. Tji Gan, Hester van der Vaart, Onno W. Akkerman, Willie N. Steenhuis, Marieke Verkleij, Harry G.M. Heijerman, Erik A.M. Verschuuren

“…Background: Elexacaftor/Tezacaftor/Ivacaftor (ETI) for people with CF (PwCF) after lung transplantation (LTx) has been restrained due to uncertainties regarding efficacy and drug interactions. …”
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Global decadal measurements of methanol, ethene, ethyne, and HCN from the Cross-track Infrared Sounder by K. C. Wells, D. B. Millet, J. F. Brewer, V. H. Payne, K. E. Cady-Pereira, R. Pernak, S. Kulawik, S. Kulawik, C. Vigouroux, N. Jones, E. Mahieu, M. Makarova, T. Nagahama, I. Ortega, M. Palm, K. Strong, M. Schneider, D. Smale, R. Sussmann, M. Zhou

“…Initial comparisons of the CrIS observations to predicted VOC distributions from the GEOS-Chem chemical transport model point to large uncertainties in our current<span id="page696"/> understanding of the atmospheric ethene budget as well as to underestimated HCN, ethyne, and methanol sources.…”
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Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

“…However, we encountered challenges that complicated pleural infection interpretation, including: (i) uncertainties regarding microbial pathogenicity and the impact of prior antibiotic therapy on diagnostic performance; (ii) lack of a clinical diagnostic gold-standard for molecular performance comparisons; (iii) potential microbial contamination during specimen collection or processing; and (iv) difficulties distinguishing background microbial noise from true microbial signal in low-biomass specimens. …”
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After neonatal care, what next? A qualitative study of mothers’ post-discharge experiences after premature birth in Kenya by Justinah Maluni, Dorothy Oluoch, Sassy Molyneux, Mwanamvua Boga, Caroline Jones, Florence Murila, Mike English, Sue Ziebland, Lisa Hinton

“…For mothers of premature babies, the transition home from hospital is marked by challenges and uncertainties. This study explored the post-discharge experiences of mothers of premature babies with the aim of identifying their needs and suggests strategies to strengthen and support their discharge preparation to care for their premature baby at home, and to and reduce mortality and readmission rates. …”
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Evaluation of mechanical and thermal performance of jute and coconut fiber-reinforced epoxy composites with rice husk ash for wall insulation applications by Md. Ahtesham Akhter, Dipayan Mondal, Arup Kumar Debnath, Md. Ashraful Islam, Md. Sanaul Rabbi

“…However, the combined uncertainties of mechanical properties (tensile and flexural) are estimated at 4.57 % and 4.93 %, respectively, while estimated at 5.67 % for thermal conductivity measurement. …”
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Nesting population trend of the leatherback sea turtle in Bocas del Toro province and Comarca Ngäbe-Buglé, Panama for the period 2002–2022 by Sonia Gutiérrez Parejo, Susan E. Piacenza, Raúl García, Cristina Ordóñez, Roldán A. Valverde

“…However, despite progress in assessments, demographics, and ecology, key uncertainties persist in tracking leatherback population trends. …”
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A sea ice deformation and rotation rate dataset (2017–2023) from the Environment and Climate Change Canada automated sea ice tracking system (ECCC-ASITS) by M. Plante, J.-F. Lemieux, L. B. Tremblay, A. Bouchat, D. Ringeisen, D. Ringeisen, P. Blain, S. Howell, M. Brady, A. S. Komarov, B. Duval, L. Yakuden, F. Labelle

“…It covers the entire Arctic Ocean and all peripheral seas except the Okhotsk Sea. Uncertainties associated with the propagation of tracking errors on the deformation values are included. …”
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Strong-lensing Analysis of SPT-CL J2325−4111 and SPT-CL J0049−2440, Two Powerful Cosmic Telescopes (RE > 40″) from the SPT Clusters Sample by Guillaume Mahler, Keren Sharon, Matthew Bayliss, Lindsey. E. Bleem, Mark Brodwin, Benjamin Floyd, Raven Gassis, Michael D. Gladders, Gourav Khullar, Juan D. Remolina González, Arnab Sarkar

“…We conclude that these clusters are spectacular sightlines for further observations that will reduce the systematic uncertainties due to cosmic variance. This paper provides the community with two additional well-calibrated cosmic telescopes, as strong as the Frontier Fields and suitable for studies of the highly magnified background Universe.…”
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Quantification of regional net CO₂ flux errors in the Orbiting Carbon Observatory-2 (OCO-2) v10 model intercomparison project (MIP) ensemble using airborne measurements by J. Yun, J. Liu, J. Liu, B. Byrne, B. Weir, B. Weir, L. E. Ott, K. McKain, B. C. Baier, L. V. Gatti, S. C. Biraud

“…<p>Inverse model intercomparison projects (MIPs) provide a chance to assess the uncertainties in inversion estimates arising from various sources. …”
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Molecular Data Confirm the Occurrence of the Allochthonous <i>Gambusia holbrooki</i> (Pisces: Poeciliidae) in Sicily and the Maltese Archipelago by Luca Vecchioni, Mirko Liuzzo, Arnold Sciberras, Jeffrey Sciberras, Justin Formosa, Alan Deidun, Gabriele Giacalone, Vincenzo Arizza, Marco Arculeo, Federico Marrone, Francesco Paolo Faraone

“…However, due to taxonomic uncertainties and nomenclatural instability, for years, there were doubts about which <i>Gambusia</i> species had been introduced in different regions. …”
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Identifying and Ranking the Causes of Delay Based on Production Strategies in Manufacturing Projects by Mohsen Rouzbahani, Mohammad Forozandeh

“…Purpose: Today, due to the increase in complexities and uncertainties faced by manufacturing organizations, the production of products faces planned/unplanned events that happen during the production life cycle. …”
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Peningkatan Akurasi Metode Weighted Fuzzy Time Series Forecasting Menggunakan Algoritma Evolusi Differensial dan Fuzzy C-Means by Agus Fachrur Rozy, Solimun Solimun, Ni Wayan Surya Wardhani

“…Abstract Prediction is a form of approach in anticipating future uncertainties. Conventional prediction methods encounter difficulties in adapting data with the assumptions used, necessitating the application of the Weighted Fuzzy Time Series (WFTS) method. …”
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Climate change rivals fertilizer use in driving soil nitrous oxide emissions in the northern high latitudes: Insights from terrestrial biosphere models by Naiqing Pan, Hanqin Tian, Hao Shi, Shufen Pan, Josep G. Canadell, Jinfeng Chang, Philippe Ciais, Eric A. Davidson, Gustaf Hugelius, Akihiko Ito, Robert B. Jackson, Fortunat Joos, Sebastian Lienert, Dylan B. Millet, Stefan Olin, Prabir K. Patra, Rona L. Thompson, Nicolas Vuichard, Kelley C. Wells, Chris Wilson, Yongfa You, Sönke Zaehle

“…The rigorous interplay between process modeling and field experimentation will be essential for improving model representations of the mechanisms controlling N2O fluxes in the Northern High Latitudes and for reducing associated uncertainties.…”
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Co-benefits of nature-based solutions: A health impact assessment of the Barcelona Green Corridor (Eixos Verds) plan by Tamara Iungman, Sergi Ventura Caballé, Ricard Segura-Barrero, Marta Cirach, Natalie Mueller, Carolyn Daher, Gara Villalba, Evelise Pereira Barboza, Mark Nieuwenhuijsen

“…Preventable mortality at the census tract level for adult residents was estimated, and to address uncertainties, we performed Monte Carlo iterations. We computed the percentage increase in GS (land use) and tree cover and converted them into Normalized Difference Vegetation Index (NDVI) to conduct the HIA, employing a Generalized Additive Model (GAM). …”
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