Comparative analysis of phytonutrients of Moringa oleifera leaves from South Africa and Nigeria, and their antimicrobial and antioxidant potentials by UPLC-ESI-QToF-MS and OPLS-DA... by Jonathan Kayembe, Cosa Sekelwa, Kokoette Bassey

“…This study aimed to conduct a comparative analysis of the phytonutrients (nutrients protectors) or supplements, antioxidant, and antimicrobial potentials of M. oleifera leaves from Nigeria and South Africa to benchmark quality control protocols for commercial beverages such as Moringa porridge.MethodsStandard techniques, including high-performance liquid chromatography-photodiode array and ultra-high-performance liquid chromatography electrospray ionization quadruple time-of-flight mass spectrometry (UPLC-ESI-QToF-MS) and chemometrics orthogonal partial least square discriminant analysis (OPLS-DA) were employed for phytoconstituents fingerprinting. …”
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The effect of trace minerals on the stability of retinol acetate, cholecalciferol and selenomethionine stability within premixes by M. Concarr, I. Sinkunaite, R. Murphy

“…The vitamin content of the four vitamin-trace mineral premixes was analysed after 14 and 84 days in storage by ultra-high performance liquid chromatography and the amount present within each of the premixes was compared to the quantity determined prior to storage. …”
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Quality of Life Philosophy IV. The Brain and Consciousness by Søren Ventegodt, Niels Jørgen Andersen, Joav Merrick

“…Although the brain at micro-level, with its trillions of ultra-thin nerve fibers, is one of the most complicated structures in the known universe, you can still grasp its composition if you go up to the level of the cell. …”
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Energy-dependent machining mechanism and process in water-jet guided laser processing single crystal diamond by Shilong Chen, Tianye Jin, Zihao Lin, Mingtao Wu, Junquan Huang, Junyun Chen, Anmin Nie

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The fastest nonprofessional age group IRONMAN triathletes in the world originate from Europe by Beat Knechtle, Elias Villiger, Katja Weiss, David Valero, Thomas Rosemann, Pantelis T. Nikolaidis, Rodrigo Luiz Vancini, Marilia Santos Andrade, Mabliny Thuany

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Characterization and Removal of Condensable Particulate Matter in Flue Gas Studied with Cold Electrode Electrostatic Precipitator by Wenting Liu, Bowen Zhao, Xin Wang, Jianyi Lu

“…According to the study, CPM was emitted at the stack inlet with an average concentration of 30.2 mg Nm−3, which far exceeds the concentration of FPM (3.7 mg Nm−3) and the Chinese ultra-low emission (ULE) standard for particulate matter. …”
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Evaluation of the effect of Irritrol as final irrigant against Staphylococcus epidermidis: an in Vitro Study. by Hezha Saadi Hassan, Diyar Khalid Bakr

“…All samples were prepared and instrumented by using ProTaper NEXT rotary system till X3. 5.25% NaOCl was applied with a 27‐G double side‐vented syringe needle as an initial irrigant then followed by the final irrigants. Ultra X ultrasonic device was used for the activation of irrigation with a high degree of 45,000 kHz and using tip size 20# with taper of 2%. …”
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Bit selection method based on the rock drillability characteristics and principal component analysis of rock-breaking indicators by Yang Hu, Xian Xinlong, Zhou Penggao, Li Zhen, Wei Ruihua, Liang Junqiao, Xiong Shilong

“…Ultra-deep oil and gas structure is the key field of exploration and development in the southern margin of Junggar Basin. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India by Karthika Maniyara, Prakash Babu Kodali

“…Educational programs on diet and physical activity, creation of public spaces conducive to physical activity, promotion of fruit and vegetable intake, and discouragement of processed and ultra-processed diets can directly address inadequate physical activity and obesity, the two primary modifiable risk factors for type-2 diabetes. …”
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Relationship Between the Salivary Microbiome and Oral Malodor Metabolites in Older Thai Individuals with Periodontitis and the Cytotoxic Effects of Malodor Compounds on Human Oral... by Witsanu Srila, Kritsana Sripilai, Thunwa Binlateh, Peungchaleoy Thammanichanon, Watcharaphol Tiskratok, Parinya Noisa, Paiboon Jitprasertwong

“…<b>Methods</b>: Saliva samples were collected and analyzed using Ultra-High Performance Liquid Chromatography–Mass Spectrometry (UHPLC-MS) to identify metabolites. …”
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Analysis of Radio Science Data from the KaT Instrument of the 3GM Experiment During JUICE’s Early Cruise Phase by Paolo Cappuccio, Andrea Sesta, Mauro Di Benedetto, Daniele Durante, Umberto De Filippis, Ivan di Stefano, Luciano Iess, Ruaraidh Mackenzie, Bernard Godard

“…The 3GM experiment employs a Ka-band Transponder (KaT) to enable two-way coherent range and Doppler measurements used for the gravity experiment and an Ultra Stable Oscillator (USO) for one-way downlink occultation experiments. …”
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A SPectroscopic Survey of Biased Halos in the Reionization Era (ASPIRE): Spectroscopically Complete Census of Obscured Cosmic Star Formation Rate Density at z = 4–6 by Fengwu Sun, Feige Wang, Jinyi Yang, Jaclyn B. Champagne, Roberto Decarli, Xiaohui Fan, Eduardo Bañados, Zheng Cai, Luis Colina, Eiichi Egami, Joseph F. Hennawi, Xiangyu Jin, Hyunsung D. Jun, Yana Khusanova, Mingyu Li, Zihao Li, Xiaojing Lin, Weizhe Liu, Romain A. Meyer, Maria A. Pudoka, George H. Rieke, Yue Shen, Wei Leong Tee, Bram Venemans, Fabian Walter, Yunjing Wu, Huanian Zhang, Siwei Zou

“…This is significantly higher than previous determinations using ALMA data in the Hubble Ultra Deep Field, which is void of DSFGs at z = 4–6 because of strong cosmic variance (shot noise). …”
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Partially Isolated Dual Work Function Gate IGZO TFT With Obviously Reduced Leakage Current for 3D DRAMs by Yunjiao Bao, Gangping Yan, Lei Cao, Chuqiao Niu, Qingkun Li, Guanqiao Sang, Lianlian Li, Yanzhao Wei, Xuexiang Zhang, Jie Luo, Yanyu Yang, Gaobo Xu, Huaxiang Yin

“…The PIDWF gate IGZO TFT exhibits scalability and is capable of achieving an 84.6% reduction in leakage current even with ultra-short channel lengths, which offers a promising application for future 3D DRAM applications with little extra cost.…”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…IntroductionFerula communis has demonstrated an abundance of pharmacological and antioxidative qualities.MethodsThis study investigates the antioxidant activity of F. communis leaf aqueous extract, total polyphenol and flavonoid concentrations, and ultra-high-performance liquid chromatography (UHPLC) composition and then evaluates the toxicity of the plant’s leaves in vitro and in silico. …”
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Ice-nucleating particles active below −24&thinsp;°C in a Finnish boreal forest and their relationship to bioaerosols by F. Vogel, F. Vogel, M. P. Adams, L. Lacher, P. B. Foster, G. C. E. Porter, G. C. E. Porter, B. Bertozzi, B. Bertozzi, K. Höhler, J. Schneider, T. Schorr, N. S. Umo, J. Nadolny, Z. Brasseur, P. Heikkilä, E. S. Thomson, N. Büttner, M. I. Daily, R. Fösig, A. D. Harrison, J. Keskinen, U. Proske, U. Proske, U. Proske, J. Duplissy, J. Duplissy, M. Kulmala, T. Petäjä, O. Möhler, B. J. Murray

“…Using the 6 <span class="inline-formula">min</span> time resolution PINE data, we present several lines of evidence that INPs below <span class="inline-formula">−</span>24 <span class="inline-formula">°C</span> in this location are also from biological sources: (i) an INP parameterization developed for a pine forest site in Colorado, where many INPs were shown to be biological, produced a good fit to our measurements; a moderate correlation of INPs with aerosol concentration larger than 0.5 <span class="inline-formula">µm</span> and the fluorescent bioaerosol concentration; (ii) a negative correlation with relative humidity that may relate to enhanced release of bioaerosol at low humidity from local sources such as the prolific lichen population in boreal forests; and (iii) the absence of correlation with ultra-fine particles (3.5 to 50 <span class="inline-formula">nm</span>), indicating that new particle formation events are not sources of INPs. …”
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Danlian-Tongmai formula improves diabetic vascular calcification by regulating CCN3/NOTCH signal axis to inhibit inflammatory reaction by Wenting Wang, Yiwen Li, Mengmeng Zhu, Qian Xu, Jing Cui, Yanfei Liu, Yanfei Liu, Yue Liu

“…This study aims to elucidate the effects of DLTM on DVC and explore the underlying mechanisms of action.MethodsUltra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) was used to identify the metabolites of DLTM. …”
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Rapid Determination of Pemetrexed Concentration and Distribution in Human Breast Cancer Cells (McF-7) Based on UHPLC-MS/MS by Mengwei Zhang, Zhipeng Wang, Qiqiang Zhang, Qing Ye, Fengjing Xu, Lili Cui, Yanping Liu, Shouhong Gao, Wansheng Chen, Yan Liu

“…Pemetrexed is a new multitarget folate antagonist with pyrrolidine group as its core structure. An ultra high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method was developed for rapid quantification of pemetrexed concentration in human breast cancer cells (MCF-7). …”
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Aerodynamic energy consumption analysis of divided evacuated tube transportation system by Ziwei Zhang, Yingxue Wang, Guanqing Wang, Feilong Li, Dengke Wang, Jianjun Luo

“…The saving ratio of aerodynamic drag energy consumption of a 10 km tube could be 39.9% compared to traditional tunnels, which will be higher under ultra-long mileage, thus realising the overall aerodynamic energy saving effect. …”
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Study on optimization of extraction and purification processes for total flavonoids from Lycopi herba roots and their anti-proliferative effects on fibrous synoviocytes in human rh... by Jie Chen, Chunyang Jiang, Zhenyu Liu, Panpan Wang, Qiang Ma, Nong Zhou

“…By further refining the purification conditions through RSM, the purity of flavonoids was increased to 63.9 ± 1.86 %. Through ultra performance liquid chromatography tandem-quadrupole time-of-flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS) analysis, 74 flavonoid compounds across 15 categories were identified. …”
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