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1661
Effect of metformin on the level of aqueous humor inflammatory cytokines in patients with cataract
Published 2025-01-01“…Abstract This study investigated the content of inflammatory cytokines in the aqueous humor (AH) of cataract patients with type 2 diabetes (T2DM) and explored the effect of metformin on the level of cytokines. …”
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1662
Long-term Follow-up of Patients Undergoing Nephrectomy for Urolithiasis
Published 2025-01-01“…Results: Among 107 patients followed for an average of 83.5 months, type 2 diabetes mellitus (T2DM) significantly increased the risk of progression to stage 3 CKD by 34.79-fold (p=0.004). …”
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1663
Association between Intrapancreatic Fat Deposition and Lower High-Density Lipoprotein Cholesterol in Individuals with Newly Diagnosed T2DM
Published 2023-01-01“…Intrapancreatic fat deposition (IPFD) usually occurs in individuals with type 2 diabetes mellitus (T2DM), but its physiopathological influence remains controversial. …”
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1664
Hubungan antara Kadar HbA1c dan Derajat Retinopati Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Mata Cicendo Bandung
Published 2023-07-01“…Conclusion: HbA1c levels in Type 2 Diabetes Mellitus patients have a significant association with the severity of diabetic retinopathy, which can be used as a parameter for controlling diabetes complications, particularly retinopathy. …”
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1665
The Reach of Depression Screening Preceding Treatment: Are There Patterns of Patients' Self-Selection?
Published 2012-01-01“…A two-item Patient Health Questionnaire-Depression was sent to 4196 type 2 diabetic patients. Positively screened patients were interviewed to assess the severity of depression, and those with subclinical symptoms were invited to treatment groups. …”
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1666
Coats-Like reaction post-vitreoretinal surgery for PDR managed with laser photocoagulation and adjunctive intravitreal steroids– a case report
Published 2025-01-01“…Case description A 52-year-old woman with a five-year history of type 2 diabetes mellitus and hypertension presented with decreased vision in the left eye (counting fingers at 1 m). …”
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1667
The Effect of Tianmai Xiaoke Pian on Insulin Resistance through PI3-K/AKT Signal Pathway
Published 2016-01-01“…In the clinical setting, given the potential adverse effects of thiazolidinediones and biguanides, we often have difficulty in treatment that no other insulin sensitizers are available for use in type 2 diabetic mellitus (T2DM) patients. Tianmai Xiaoke Pian (TMXKP) is a traditional Chinese medicine tablet, which is comprised of chromium picolinate, Tianhuafen, Maidong, and Wuweizi. …”
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1668
Electrodiagnostic assessment of autonomic nervous system in diabetic autonomic neuropathy: Case series in 72 diabetes patients
Published 2025-01-01“…Seventy-two diagnosed Type-2 Diabetes mellitus patients were examined using POWER LAB AND LAB CHART 8 BY AD INSTRUMENT: For recording heart rate variability (HRV) and Ewing’s battery of tests: For Autonomic function testing. …”
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1669
Asymptomatic Urinary Abnormalities Among Unselected Adults in a Rural Community in Bauchi, Northeast Nigeria
Published 2024-07-01“…Hyperglycemia was seen in 2.5% of the subjects, including two subjects who were known to have type 2 diabetes mellitus on oral hypoglycemic agents. …”
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1670
Poor control of oxidative stress index is associated with increased DNA methylation in retinopathy patients of a sample from babylonian population
Published 2024-01-01“…Materials and Methods: The study included 120 participants, of whom 40 were healthy, 40 patients with retinopathy, and 40 non-retinopathy diabetes patients (type 2 diabetes mellitus (T2DM)). The total antioxidant, capacity (TAC) evaluated using Cupric ion reducing antioxidant capacity method. …”
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1671
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro
Published 2021-01-01“…Background: Metabolic associated fatty liver disease (MAFLD), characterized by hepatic lipid accumulation and fatty degeneration, is intertwined with obesity and type 2 diabetes mellitus (T2DM). Empagliflozin is a sodium-glucose cotransporter-2 inhibitor that effectively lowers blood glucose, but its effect on MAFLD and associated mechanisms are not fully understood.Methods: Eight-week-old db/db mice, an in vivo model, were administered empagliflozin or saline intragastrically. …”
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1672
The Food Resources and Kitchen Skills intervention: Protocol of a randomized controlled trial.
Published 2025-01-01“…<h4>Introduction</h4>Individuals with food insecurity are disproportionately burdened by hypertension (HTN) and type 2 diabetes and face greater barriers to self-managing these conditions.…”
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1673
The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review.
Published 2025-01-01“…In total, the urobiome of 1,571 people was sequenced, of which 662 people had diabetes, and of these 36 had confirmed diabetic kidney disease; 609 were healthy individuals, 179 had prediabetes or were at risk of type 2 diabetes mellitus and 121 did not have diabetes but had other comorbidities. …”
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1674
Integrating mandatory occupational health practice and workplace health promotion programs to reduce the high burden of work-related diseases
Published 2023-06-01“…Sedentary occupations and metabolic syndrome (MetS) are associated with an increased risk of type 2 diabetes mellitus (T2DM) and coronary heart disease, contributing to elevated mortality rates from CVDs. …”
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1675
Nonsevere Hypoglycemia Episode Clinical and Economic Outcomes: A Comparison between Sulfonylurea and Sodium-Glucose Cotransporter 2 Inhibitor as Add-On to Metformin from a Canadian...
Published 2018-01-01“…To estimate prevalence of NSHEs and associated economic outcomes attributable to sulfonylurea (SU) versus sodium-glucose cotransporter 2 inhibitor (SGLT2i) initiation after metformin over one year for Canadian patients with type 2 diabetes (T2DM). Methods. Risk difference for NSHEs was calculated for SU and SGLT2i from RCT data. …”
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1676
Genetic risk factors associated with gestational diabetes in a multi-ethnic population.
Published 2021-01-01“…<h4>Aims</h4>Genome-wide association studies have shown an increased risk of type-2-diabetes (T2DM) in patients who carry single nucleotide polymorphisms in several genes. …”
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1677
Nomogram-Based Prediction of the Risk of Diabetic Retinopathy: A Retrospective Study
Published 2020-01-01“…This study is aimed at developing a risk nomogram of diabetic retinopathy (DR) in a Chinese population with type 2 diabetes mellitus (T2DM). Methods. A questionnaire survey, biochemical indicator examination, and physical examination were performed on 4170 T2DM patients, and the collected data were used to evaluate the DR risk in T2DM patients. …”
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1678
Utility of Tetrahydrobiopterin Pathway in the Assessment of Diabetic Foot Ulcer: Significant and Complex Interrelations
Published 2019-01-01“…Tetrahydrobiopterin (BH4) pathway that included generation of neopterin (Neop), biopterin (Biop), and nitric oxide (NO) is altered in type 2 diabetes (T2D). The aim of this study was to assess the biomarkers of BH4 pathway in noninfected DFUs and to relate these levels to the variables of diabetes as well as to the hematological indices. …”
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1679
Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D
Published 2024-01-01“…This multicenter cross-sectional study was performed on two groups of adults (nondiabetes and type 2 diabetes) of various ages, sexes, and body mass index (BMI). …”
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1680
Identification of Flavonoid C-Glycosides as Promising Antidiabetics Targeting Protein Tyrosine Phosphatase 1B
Published 2022-01-01“…Protein tyrosine phosphatase 1B (PTP1B), a negative regulator of the insulin signaling pathway, has gained attention as a validated druggable target in the management of type 2 diabetes mellitus (T2DM). The lack of clinically approved PTP1B inhibitors has continued to prompt research in plant-derived therapeutics possibly due to their relatively lesser toxicity profiles. …”
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