Uninephrectomy and sodium‐glucose cotransporter 2 inhibitor administration delay the onset of hyperglycemia by Yuri Sakai Ishizaki, Masao Kikuchi, Koichi Kaikita, Shouichi Fujimoto

“…Therefore, this study aimed to evaluate how each uninephrectomy (UNx) and SGLT2 inhibitor affects blood glucose concentrations and SGLTs dynamics in rats with type 2 diabetes mellitus. Male rats were divided into four treatment groups: sham + placebo, sham + dapagliflozin, UNx + placebo, and UNx + dapagliflozin. …”
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Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus by Yang Xin Zi Xu, Shengyan Xi, Xiaoyan Qian

“…We further reviewed them and their relatives in relation to type 2 diabetes mellitus and found more evidence of metabolic benefits. …”
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On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides by Marianna Flora Tomasello, Alessandro Sinopoli, Giuseppe Pappalardo

“…Pancreatic islets in type 2 diabetes mellitus (T2DM) patients are characterized by reduced β-cells mass and diffuse extracellular amyloidosis. …”
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Association of the Cardioankle Vascular Index and Ankle-Brachial Index with Carotid Artery Intima Media Thickness in Hemodialysis Patients by Tomohito Gohda, Hiromichi Gotoh, Yoshikazu Gotoh, Saori Yamaguchi, Yasuhiko Tomino

“…The objectives of the present study are (1) to compare the cardioankle vascular index (CAVI), ankle-brachial index (ABI), and carotid artery intima-media thickness (CA-IMT) between HD patients with and without type 2 diabetes (T2D) or prevalence of cardiovascular (CV) disease and (2) also to evaluate the relationship of these indices with CA-IMT in these patients according to ABI levels. …”
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The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders by Elisa Benetti, Fausto Chiazza, Nimesh S. A. Patel, Massimo Collino

“…The combination of obesity and type 2 diabetes is a serious health problem, which is projected to afflict 300 million people worldwide by 2020. …”
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Cholecystoduodenal Stenting: An Option in Complicated Acute Calculous Cholecystitis in the Elderly Comorbid Patient by Brady Bonner, Nicholas I. Brown, Varghese Pynadath Joseph, Manju Dashini Chandrasegaram

“…She was unable to have a cholecystectomy due to multiple comorbidities including morbid obesity, type 2 diabetes, Guillain–Barrè syndrome, chronic sacral pressure ulcer, and severe cardiac disease. …”
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A successful remote patient monitoring program for diabetes by Katlyn Sawyer, David Saxon, David Saxon, Richard Zane, Hemali Patel, Michael McDermott, Vatsala Singh, Helen M. Lawler

“…We enrolled 211 patients with primarily uncontrolled type 2 diabetes into the Diabetes Home and Remote Care Program (DHRCP). …”
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PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways by Yves Lecarpentier, Victor Claes, Jean-Louis Hébert

“…Dysfunction of clock genes and PPARγ may lead to hyperphagia, obesity, metabolic syndrome, myocardial infarction and sudden cardiac death, In pathological conditions, regulatory processes of the cardiovascular system may bifurcate towards new states, such as those encountered in hypertension, type 2 diabetes, and heart failure. Numerous of these oscillatory mechanisms, organized in time and space, behave far from equilibrium and are “dissipative structures”.…”
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Crescentic Glomerulonephritis and Membranous Nephropathy: A Rare Overlap by Mohamedanwar Ghandour, Heba Osman, Samer Alkassis, Alix Charles, Kristina Zalewski, Jarrett Weinberger, Yahya Malik-Osman, Zeenat Y. Bhat

“…Our patient is a 53-year-old Hispanic male with a medical history of tobacco use, type 2 diabetes mellitus, and hypertension who presented with hematuria and was found to have nephrotic range proteinuria and renal impairment. …”
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Purification, characterization and hypoglycemic activity of glycoproteins obtained from pea (Pisum sativum L.) by Gaoyixin Qin, Wu Xu, Junping Liu, Liyan Zhao, Guitang Chen

“…These results indicated that PGP2 has the potential to be developed into a functional food or natural medicine for the treatment of type 2 diabetes mellitus.…”
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Transcriptomic signatures of subcutaneous adipose tissue in patients with diabetes and coronary artery disease: a pilot study by Ilias P. Doulamis, Bernard Pan, Aspasia Tzani, Jorge Plutzky, G. William Wong, Ahmet Kilic, Risa M. Wolf

“…The exact role of subcutaneous adipose tissue in the interplay between type 2 diabetes (T2D) and coronary artery disease (CAD) is yet to be determined. …”
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Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in db/db Mice Using Cytokine Antibody Array by Xue Mei Fan, Chun Lian Huang, Yi Ming Wang, Ning Li, Qiong Lin Liang, Guo An Luo

“…Cytokines are essential promoters in the pathogenesis of diabetic nephropathy (DN) in type 2 diabetes. The following study investigates the adjustment mechanism of Tangshen formula (TSF) on cytokine expressions in db/db mice (DN animal model). …”
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Evaluation of the Association Metformin: Plantago ovata Husk in Diabetic Rabbits by Raquel Díez-Láiz, Juan J. García-Vieitez, M. José Diez-Liébana, Matilde Sierra-Vega, Ana M. Sahagún-Prieto, Ángela P. Calle-Pardo, Nélida Fernández-Martínez

“…We conclude that Plantago ovata husk intake can contribute to the oral antihyperglycemic treatment of type 2 diabetes.…”
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Lay Health Trainers Supporting Self-Management amongst Those with Low Heath Literacy and Diabetes: Lessons from a Mixed Methods Pilot, Feasibility Study by Bernadette Bartlam, Trishna Rathod, Gillian Rowlands, Joanne Protheroe

“…This article reports a mixed methods process evaluation of a pilot feasibility randomised controlled trial comparing a Lay Health Trainer (LHT) intervention and usual care for those with poorly controlled Type 2 Diabetes Melitus (T2DM). Set in a deprived area in the UK, this research explores patient and health care practitioner (HCP) views on whether a structured interview between a patient and a Lay Health Trainer (LHT), for the purpose of developing a tailored self-management plan for patients, is acceptable and likely to change health behaviours. …”
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Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes by Samira Mukhtar Buzinin, Aied Mohammed Alabsi, Alexander Tong Boon Tan, Vui King Vincent-Chong, Dasan Swaminathan

“…Most of the researches linking these two very common chronic diseases were based on type 2 diabetes mellitus and chronic periodontal disease. …”
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A Liquid-Based Cytology System, without the Use of Cytocentrifugation, for Detection of Podocytes in Urine Samples of Patients with Diabetic Nephropathy by Moritsugu Kimura, Masao Toyoda, Nobumichi Saito, Noriko Kaneyama, Han Miyatake, Eitaro Tanaka, Hirotaka Komaba, Masanori Hara, Masafumi Fukagawa

“…The study subjects were patients with type 2 diabetes. Urine samples from these patients were analyzed by the conventional method (Cytospin®) and the modified method (SurePath™). …”
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The synergistic role of gut microbiota and RNA in metabolic diseases: mechanisms and therapeutic insights by Zhuo Huang, Zhuo Huang, Qinyan Yao, Qinyan Yao, Shuang Ma, Shuang Ma, Jinjie Zhou, Jinjie Zhou, Xiaoxuan Wang, Xiaoxuan Wang, Qingguo Meng, Qingguo Meng, Yaxin Liu, Yaxin Liu, Zihan Yu, Zihan Yu, Xin Chen, Xin Chen

“…Dysbiosis of the gut microbiota has been linked to metabolic disorders such as type 2 diabetes, obesity, metabolic-associated fatty liver disease (MAFLD) and metabolic heart disease. …”
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Evaluation of the EndoPAT as a Tool to Assess Endothelial Function by M. Moerland, A. J. Kales, L. Schrier, M. G. J. van Dongen, D. Bradnock, J. Burggraaf

“…Endothelial function in renally impaired and type 2 diabetic patients was not decreased compared to healthy volunteers (2.9±1.4 and 1.8±0.3, resp., versus 1.8±0.5, P>0.05). …”
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The specificity of ten non-digestible carbohydrates to enhance butyrate-producing bacteria and butyrate production in vitro fermentation by Jingjing Xu, Ruyue Wang, Weibao Liu, Zhongwei Yin, Jianrong Wu, Xun Yu, Wen Wang, Hongtao Zhang, Zhitao Li, Minjie Gao, Li Zhu, Xiaobei Zhan

“…Ten non-digestible carbohydrates (NDCs), including inulin, fructooligosaccharide (FOS), oats β-glucans (OGS), oats β-glucan oligosaccharides (OGOS), Astragalus polysaccharides (APS), Astragalus oligosaccharides (AOS), xanthan gum oligosaccharides (XGOS), gellan gum oligosaccharides (GGOS), curdlan oligosaccharides (COS), and pullulan oligosaccharides (POS) were used to investigate NDC specificity in modulating butyrate-producing bacteria and butyrate production in 48-h in vitro fermentation studies in combination with fecal inocula from 7 healthy donors and 11 patients with type 2 diabetes (T2D). We observed that the amount of these ten NDCs utilized depended on NDC structure and inter-individual gut microbial differences. …”
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Alcohol Consumption Is a Risk Factor for Lower Extremity Arterial Disease in Chinese Patients with T2DM by Shanshan Yang, Shuang Wang, Bo Yang, Jinliang Zheng, Yuping Cai, Zhengguo Yang

“…To investigate the relationship between alcohol consumption and diabetic lower extremity arterial disease (LEAD) in hospitalized patients with type 2 diabetes mellitus (T2DM). Methods. We evaluated 138 hospitalized patients with T2DM who consumed alcohol and 833 who did not. …”
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