-
1361
Latent Inflammation and Insulin Resistance in Adipose Tissue
Published 2017-01-01“…It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. …”
Get full text
Article -
1362
Persistent Hiccups as the Only Presenting Symptom of ST Elevation Myocardial Infarction
Published 2018-01-01“…Our patient was a 74-year-old male with a past medical history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and COPD due to chronic tobacco use, who presented with persistent hiccups for 4 days and no other complaints. …”
Get full text
Article -
1363
Comorbidities and Ethnocultural Factors Limit the Physical Activity of Rural Sri Lankan Patients with Diabetes Mellitus
Published 2018-01-01“…Four hundred patients with type 2 diabetes, comprising 113 (28.2%) males and 287 (71.7%) females, were enrolled. …”
Get full text
Article -
1364
Multifunctional health-promoting effects of oolong tea and its products
Published 2022-05-01“…The potential efficacy of bioactives derived from oolong tea and their roles as promising anticancer agents, their cardio-protective benefits during hypoxic conditions, effects in treating allergic disorders, potential prebiotic activities, improvement of blood lipid status in human beings, effectivity as oral hypoglycemic agent in the treatment of type 2 diabetes, and their potentials to reduce the risk of obesity have been discussed in this review. …”
Get full text
Article -
1365
A Patient with Chronic Lymphocytic Leukemia with Pancreatic Involvement
Published 2019-01-01“…A 78-year-old female with a past medical history of hypertension, type 2 diabetes mellitus, and chronic lymphocytic leukemia was hospitalized for poor appetite, weight loss, and night sweats. …”
Get full text
Article -
1366
Computational antidiabetic assessment of Salvia splendens L. polyphenols: SMOTE, ADME, ProTox, docking, and molecular dynamic studies
Published 2025-03-01“…Overall, the findings highlight the potential of phenolic compounds from S. splendens as candidates for Type 2 diabetes management.…”
Get full text
Article -
1367
Hubungan Jumlah Komplikasi Kronik Dengan Derajat Gejala Depresi Pada Pasien Diabetes Melitus Tipe 2 Di Poliklinik Rsup Dr. M. Djamil Padang
Published 2016-09-01“…</em></p><strong><em>Keywords: </em></strong><em>:</em><em>type 2 diabetes mellitus, depression symptoms, chronic complications</em>…”
Get full text
Article -
1368
Transcultural Diabetes Nutrition Algorithm: A Malaysian Application
Published 2013-01-01“…Glycemic control among patients with prediabetes and type 2 diabetes mellitus (T2D) in Malaysia is suboptimal, especially after the continuous worsening over the past decade. …”
Get full text
Article -
1369
Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse
Published 2016-01-01“…Type 2 diabetes (T2D) is characterized by β-cell dedifferentiation, but underlying mechanisms remain unclear. …”
Get full text
Article -
1370
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice
Published 2020-01-01“…We concluded that oral pyruvate delayed DN progression in db/db mice and the modified Pyr-ORS formula might be an ideal novel therapeutic drink in clinical prevention and treatment of type 2 diabetes and DN.…”
Get full text
Article -
1371
Gender Differences in Metabolic Disorders and Related Diseases in Spontaneously Diabetic Torii-Leprfa Rats
Published 2014-01-01“…The Spontaneously Diabetic Torii Leprfa (SDT fatty) rat is a novel type 2 diabetic model wherein both male and female rats develop glucose and lipid abnormalities from a young age. …”
Get full text
Article -
1372
Open challenges for the automatic synthesis of clinical trials
Published 2025-02-01“…To address this challenge, we utilized our annotated dataset, which includes 211 abstracts of clinical trials related to glaucoma and type 2 diabetes mellitus. We then developed a tool that provides an overview of the annotated clinical trial information and enables users to group them by outcomes. …”
Get full text
Article -
1373
Tribbles 3 Regulates the Fibrosis Cytokine TGF-β1 through ERK1/2-MAPK Signaling Pathway in Diabetic Nephropathy
Published 2014-01-01“…To reveal the expression and possible role of tribbles homolog 3 (TRB3) in the incidence of type 2 diabetic nephropathy, we used immunohistochemistry, real-time quantitative PCR, western blot analysis, and enzyme-linked immunosorbent assay (ELISA) to study the expression of TRB3, extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase (ERK1/2 MAPK), transforming growth factor β1 (TGF-β1), and collagen type IV in kidneys of db/db diabetic mice and in murine renal mesangial cells stimulated with high glucose. …”
Get full text
Article -
1374
Novel Genes Potentially Involved in Fibroblasts of Diabetic Wound
Published 2021-01-01“…Furthermore, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways involved in type 2 diabetes were retrieved from miRWalk. Consequently, the integrated bioinformatic analyses revealed the shared KEGG pathways between DEG-identified and diabetes-related pathways were functionally enriched in the MAPK signaling pathway, and the MAPKAPK3, HSPA2, TGFBR1, and p53 signaling pathways were involved. …”
Get full text
Article -
1375
Bcl-2 and Bcl-xL in Diabetes: Contributions to Endocrine Pancreas Viability and Function
Published 2025-01-01“…Type 1 (T1D) and type 2 diabetes (T2D), the most common forms of diabetes, are characterized by the loss of functional pancreatic β-cells, mostly due to apoptosis. …”
Get full text
Article -
1376
Effect of Social Factors and the Natural Environment on the Etiology and Pathogenesis of Diabetes Mellitus
Published 2019-01-01“…Type 2 diabetes mellitus (T2DM) is currently a public health problem worldwide and a threat to human health and social development. …”
Get full text
Article -
1377
JAK inhibitors: a new choice for diabetes mellitus?
Published 2025-01-01“…Recently, several clinical cases involving the reversal of type 1 diabetes mellitus (T1DM) during treatment with JAK inhibitors have been reported, and clinical studies have described the improvement of type 2 diabetes mellitus (T2DM) during treatment with JAK inhibitors. …”
Get full text
Article -
1378
Metformin: A Possible Option in Cancer Chemotherapy
Published 2020-01-01“…Metformin has been used for a long time as an antidiabetic medication for type 2 diabetes. It is used either as a monotherapy or in combination with other antidiabetic medications. …”
Get full text
Article -
1379
Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology
Published 2025-01-01“…Growing evidence indicates that type 2 diabetes (T2D) is associated with an increased risk of developing Parkinson’s disease (PD) through shared disease mechanisms. …”
Get full text
Article -
1380
Recent advances in pancreatic α-cell transdifferentiation for diabetes therapy
Published 2025-01-01“…The potential clinical applications, especially in type 1 and type 2 diabetes characterized by significant β-cell dysfunction, are addressed. …”
Get full text
Article