Metformin and Fibrosis: A Review of Existing Evidence and Mechanisms by Maoyan Wu, Huiwen Xu, Jingyu Liu, Xiaozhen Tan, Shengrong Wan, Man Guo, Yang Long, Yong Xu

“…Metformin, which is a potent AMPK activator and is the only recommended first-line drug for the treatment of type 2 diabetes, has emerged as a promising method of fibrosis reduction or reversion. …”
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Recent Advances in Potential Clinical Application of Ghrelin in Obesity by Christine Delporte

“…Ghrelin is involved in weight regulation, obesity, type 2 diabetes, and metabolic syndrome. Furthermore, a better understanding of ghrelin biology led to the identification of molecular targets modulating ghrelin levels and/or its biological effects: GOAT, ghrelin, and GHS-R1a. …”
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Hubungan Jumlah Komplikasi Kronik Dengan Derajat Gejala Depresi Pada Pasien Diabetes Melitus Tipe 2 Di Poliklinik Rsup Dr. M. Djamil Padang by Try Rahmi Lussii Karsuita, Eva Decroli, Delmi Sulastri

“…<br />Keywords: :type 2 diabetes mellitus, depression symptoms, chronic complications…”
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New Onset of Diabetes Mellitus and Associated Factors among COVID-19 Patients in COVID-19 Care Centers, Addis Ababa, Ethiopia 2022 by Asaminew Habtamu Sane, Migbar Sibhat Mekonnen, Melsew Getnet Tsegaw, Wuletaw Chane Zewde, Edmialem Getahun Mesfin, Hailu Asmare Beyene, Taye Mezgebu Ashine, Kasie Gebeyehu Tiruneh, Melkie Ambaw Mengistie

“…A significant proportion of COVID-19 patients had been diagnosed with new onset of diabetes mellitus, and new-onset type 2 diabetes mellitus is the most common diabetes mellitus type. …”
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Translation of a Diabetes Remission Service into Australian Primary Care: Findings from the Evaluation of DiRECT-Australia by Ritesh Chimoriya, Kimberly Mitlehner, Chee L. Khoo, Uchechukwu Levi Osuagwu, Russell Thomson, Lei Si, Michael Lean, David Simmons, Milan K. Piya

“…All patients enrolled in the DiRECT-Australia Type 2 Diabetes Remission Service in a region of Sydney (Macarthur region, South Western Sydney, Australia) were included. …”
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FTO rs9939609 Does Not Interact with Physical Exercise but Influences Basal Insulin Metabolism in Brazilian Overweight and Obese Adolescents by Gabrielle Araujo do Nascimento, Neiva Leite, Lupe Furtado-Alle, Mayza Dalcin Teixeira, Ricardo Lehtonen Rodrigues de Souza, Gerusa Eisfeld Milano, Larissa Rosa da Silva, Juliana Pizzi, Wendell Arthur Lopes, Maria de Fátima Aguiar Lopes, Ana Cláudia Kapp Titski, Luciane Viater Tureck

“…The rs9939609 SNP (T > A) in FTO gene is associated with obesity and type 2 diabetes. The present study aimed at verifying whether this SNP influenced biochemical outcomes of children and adolescents who are overweight/obese submitted to a program of physical exercise and also if there was influence on basal levels of these biochemical variables. …”
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Evaluation of Therapeutic Benefits of a Novel Herbal Ingredient-Based Hyaluronic Acid Gel as Monotherapy for Inflammatory Enlargement of a Patient with Diabetes Mellitus by Jaahnavi Lanka, Santhosh Kumar

“…A patient aged 64 years with type 2 diabetes mellitus reported to the Department of Periodontology. …”
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Significant Calcification of an Entire Aortic Tree with Renal Artery Subocclusion: Acute Kidney Injury, Ischemic Kidney Disease, and the Tissue Viability Question—A Case Report by Marko Baralić, Selena Gajić, Aleksandra Kezić, Ana Bontić, Jelena Pavlović, Voin Brković, Vidna Karadžić Ristanović, Danka Bjelić, Maja Životić, Sanja Radojević-Škodrić, Želimir Antonić, Nenad Ilijevski, Milan Radović

“…Conclusions: Even in patients with concomitant disorders like type-2 diabetes mellitus (T2DM), hypertension (HTN), or HF, the dilatation of significantly narrowed renal arteries due to severe calcifications can result in complete renal function recovery.…”
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The Threshold of the Severity of Diabetic Retinopathy below Which Intensive Glycemic Control Is Beneficial in Diabetic Patients: Estimation Using Data from Large Randomized Clinica... by Yuqi Liu, Juan Li, Jinfang Ma, Nanwei Tong

“…However, these are realized only if the HbA1c in type 1 or type 2 diabetic patients is reduced at least by 0.8% versus the control group or it is reduced to <7% and >3 years of intensive glucose control is required. …”
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Adropin as an indicator of T2DM and its complications by Hu Zhang, Ning Chen

“…Type 2 diabetes mellitus (T2DM) is one of metabolic diseases with the major inducer of obesity. …”
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Cytokines and HCV-Related Disorders by Poupak Fallahi, Clodoveo Ferri, Silvia Martina Ferrari, Alda Corrado, Domenico Sansonno, Alessandro Antonelli

“…The most important systemic HCV-related extrahepatic diseases—mixed cryoglobulinemia, lymphoproliferative disorders, thyroid autoimmune disorders, and type 2 diabetes—are associated with a complex dysregulation of the cytokine/chemokine network, involving proinflammatory and Th1 chemokines. …”
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Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy by Joselyn Rojas, Valmore Bermudez, Jim Palmar, María Sofía Martínez, Luis Carlos Olivar, Manuel Nava, Daniel Tomey, Milagros Rojas, Juan Salazar, Carlos Garicano, Manuel Velasco

“…Describing the diverse molecular mechanisms (particularly immunological) involved in the death of the pancreatic beta cell in type 1 and type 2 diabetes mellitus. Recent Findings. Beta cell death is the final event in a series of mechanisms that, up to date, have not been entirely clarified; it represents the pathophysiological mechanism in the natural history of diabetes mellitus. …”
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Genetic, Functional, and Immunological Study of ZnT8 in Diabetes by Qiong Huang, Jie Du, Chengfeng Merriman, Zhicheng Gong

“…A common ZnT8 gene (SLC30A8) polymorphism increases the risk of type 2 diabetes mellitus (T2DM), and rare mutations may present protective effects. …”
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Attitudes Regarding Participation in a Diabetes Screening Test among an Assyrian Immigrant Population in Sweden by Susanne Andersson, Veronika Karlsson, Louise Bennet, Klas Fellbrant, Margareta Hellgren

“…Immigrants from the Middle East have higher prevalence and incidence of type 2 diabetes (T2D) compared with native Swedes. The aim of the study was to describe and understand health beliefs in relation to T2D as well as attitudes regarding participation in a screening process in a local group of Assyrian immigrants living in Sweden. …”
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Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular Complications by Almudena Gómez-Hernández, Nuria Beneit, Sabela Díaz-Castroverde, Óscar Escribano

“…These new treatments may contribute not only to reduce obesity but also to prevent highly prevalent complications such as type 2 diabetes and other vascular alterations, such as hypertension or atherosclerosis.…”
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Effects of Bariatric Surgeries on Fetuin-A, Selenoprotein P, Angiopoietin-Like Protein 6, and Fibroblast Growth Factor 21 Concentration by Jakub Poloczek, Wojciech Kazura, Ewa Kwaśnicka, Janusz Gumprecht, Jerzy Jochem, Dominika Stygar

“…It is also associated with the leading causes of death, including type 2 diabetes mellitus, cardiovascular diseases, and numerous types of cancer. …”
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Diagnosis of a Morgagni-Stewart-Morel Syndrome in a Patient with Ischemic Stroke. Report of a Case by Masleidy Valladares Valle, Juan Ibrahim García Leonard, Ada Sánchez Lozano

“…The case of a 77-year-old patient with a history of type 2 diabetes mellitus, systemic arterial hypertension and psychiatric disorder, who was admitted to the Neurology Service of the Dr. …”
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Pseudomonas mendocina bacteraemia secondary to cellulitis – a report and brief series of cases by Jorge Reis, Francisca Carmo, Inês Soares, Catarina Salvado, Mariana Fidalgo

“…Case description: An 86-year-old Caucasian male, with several vascular risk factors (type 2 diabetes, hypertension, dyslipidaemia, coronary heart disease and heart failure), who presented long-standing lower limb phlyctens for which he was being treated, developed lower limb cellulitis. …”
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Emerging nanomedicine strategies for hepatocellular carcinoma therapy by Chen Guo, Jiayu Zhang, Xiaomeng Cai, Rui Dou, Jiaruo Tang, Zhengyuan Huang, Xueting Wang, Yan Guo, Hanqing Chen, Jun Chen

“…Abstract Hepatocellular carcinoma (HCC) is a prevalent malignant tumor with a range of risk factors, including viral infections, alcoholic liver disease, exposure to fungal toxins, obesity, and type 2 diabetes. Despite advancements in early detection and treatment, HCC continues to exhibit a high rate of recurrence. …”
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Current treatment landscape for obesity in Singapore by Phong Ching Lee, Chin Hong Lim, Ravishankar Asokkumar, Marvin Wei Jie Chua

“…The rising prevalence of obesity in Singapore is a harbinger for a corresponding increase in obesity-related complications such as type 2 diabetes mellitus (T2DM) and coronary heart disease. …”
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