Microbiota for production of wine with enhanced functional components by Armachius James, Ting Yao, Hengming Ke, Yousheng Wang

“…Moderate wine consumption, particularly red wine has been associated with functional benefits to human health, which includes anti-inflammation, promoting healthy aging, prevention of cardiovascular diseases, cancers, type 2 diabetes and metabolic syndrome. Indeed, the management of microbiota allows the production of wine with distinct features and functional components that benefits human health. …”
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Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols by Qi Ge, Liang Chen, Keping Chen

“…Additionally, certain polyphenols found in spices might improve glucose homeostasis and insulin resistance in diabetes patients, thereby constituting promising options for the treatment of type 2 diabetes.…”
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The Growing Obesity Epidemic: Integrating Lifestyle, Pharmacological, and Surgical Interventions for Effective Management by Jan Siwiec, Olga Śpiołek, Agnieszka Wąsowicz, Marcelina Sztyler-Krąkowska, Mateusz Teofilak, Natalia Smyl, Aleksandra Słowikowska, Julia Szatkowska, Franciszek Kędziora, Dariusz Fabian

“… Introduction: Obesity is a multifactorial disease with a growing global prevalence, significantly increasing the risk of numerous health conditions, including type 2 diabetes and cardiovascular diseases. Its management requires a multifaceted approach that includes lifestyle modifications, pharmacologic interventions and, in severe cases, surgical treatments. …”
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Pharma TARP: A Troubled Asset Relief Program for Novel, Abandoned Projects in the Pharmaceutical Industry by Tamas Bartfai, Graham Vaughan Lees

“…Society has a real need for the drugs that are no longer going to be developed for, among others, drug-resistant epilepsy, neuropathic and cancer pain, type-2 diabetes, obesity, and schizophrenia. The authors propose a radical response by the U.S. government and the National Institutes of Health to rescue these abandoned projects, and to continue selected programs for drug approval by the U.S. …”
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A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications by Francesca Conserva, Loreto Gesualdo, Massimo Papale

“…Diabetic nephropathy (DN), a microvascular complication occurring in approximately 20–40% of patients with type 2 diabetes mellitus (T2DM), is characterized by the progressive impairment of glomerular filtration and the development of Kimmelstiel-Wilson lesions leading to end-stage renal failure (ESRD). …”
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Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism by Tsuyoshi Goto, Nobuyuki Takahashi, Shizuka Hirai, Teruo Kawada

“…Because PPARs are dietary lipid sensors that control energy homeostasis, daily eating of these terpenoids might be useful for the management for obesity-induced metabolic disorders, such as type 2 diabetes, hyperlipidemia, insulin resistance, and cardiovascular diseases.…”
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Renal and Vascular Mechanisms of Thiazolidinedione-Induced Fluid Retention by Tianxin Yang, Sunhapas Soodvilai

“…Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor subtype γ (PPARγ) activators that are clinically used as an insulin sensitizer for glycemic control in patients with type 2 diabetes. Additionally, TZDs exhibit novel anti-inflammatory, antioxidant, and antiproliferative properties, indicating therapeutic potential for a wide variety of diseases associated with diabetes and other conditions. …”
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Insulin Resistance: A Proinflammatory State Mediated by Lipid-Induced Signaling Dysfunction and Involved in Atherosclerotic Plaque Instability by Fabrizio Montecucco, Sabine Steffens, François Mach

“…This condition characterizes several diseases, such as type 2 diabetes, impaired glucose tolerance (IGT), impaired fasting glucose (IFG), obesity, hypertension, dyslipidemia, and other endocrinopathies, but also cancer. …”
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Rehabilitative Treatment as an Alternative in Amputee Patients. Case Report and Literature Review by Ismaray Sacerio González, Elohilda de la Caridad Cruz Jiménez, Silvia Georgina de la Torre Castellanos

“…The case of a 52-year-old male patient is presented, with a history of type 2 diabetes mellitus and arterial hypertension controlled by treatment, in addition to suffering from hereditary thrombopathy treated with anticoagulants, which is why he underwent surgical treatment. …”
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An Immunomodulatory Device Improves Insulin Resistance in Obese Porcine Model of Metabolic Syndrome by Angela J. Westover, Kimberly A. Johnston, Deborah A. Buffington, H. David Humes

“…These results allow for the planning of first-in-man studies in obese type 2 diabetic patients.…”
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Virtual Screening as a Technique for PPAR Modulator Discovery by Stephanie N. Lewis, Josep Bassaganya-Riera, David R. Bevan

“…It is well recognized that PPARγ agonists have therapeutic applications as insulin sensitizers in type 2 diabetes or as anti-inflammatories. VS is a cost- and time-effective means for identifying small molecules that have therapeutic potential. …”
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Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids by Ekta Lachmandas, Corina N. A. M. van den Heuvel, Michelle S. M. A. Damen, Maartje C. P. Cleophas, Mihai G. Netea, Reinout van Crevel

“…Type 2 diabetes mellitus confers a threefold increased risk for tuberculosis, but the underlying immunological mechanisms are still largely unknown. …”
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Metformin in the treatment of colorectal cancer and neuroendocrine tumours by Karolina Daniłowska, Natalia Picheta, Barbara I. Krupska, Anna Rudzińska, Oliwia Burdan, Katarzyna Szklener

“…Metformin, a drug commonly used in the treatment of type 2 diabetes, has demonstrated its ability to reduce the incidence and increase the efficacy of chemotherapy in colorectal cancer and neuroendocrine tumors. …”
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Ozone therapy as support in the treatment of diabetic foot ulcer. A case report by Isidro Matos Lamote, Jorge Enrique Rodríguez León, Carlos García Arencibia, Maydelin Pérez Reina

“…The case of a 43-years-old patient with a diagnosis of type 2 diabetes mellitus, of seven years of evolution, referred from the Emergency Department of the Dr. …”
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Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease by Tsuneo Takenaka, Takahiko Sato, Hitoshi Hoshi, Nobutaka Kato, Keita Sueyoshi, Masahiro Tsuda, Yusuke Watanabe, Hiroshi Takane, Yoichi Ohno, Hiromichi Suzuki

“…Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. …”
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Advances in Murine Models of Diabetic Nephropathy by Li-li Kong, Hao Wu, Wen-peng Cui, Wen-hua Zhou, Ping Luo, Jing Sun, Hang Yuan, Li-ning Miao

“…Diabetic nephropathy (DN) is one of the microvascular complications of both type 1 and type 2 diabetes, which is also associated with a poor life expectancy of diabetic patients. …”
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The hypoglycemic potential of phenolics from functional foods and their mechanisms by Oksana Golovinskaia, Chin-Kun Wang

“…Long-term postprandial hyperglycemia is a primary risk factor for developing chronic metabolic diseases such as obesity, type 2 diabetes, and cardiovascular disease. Chronic hyperglycemia induces the glycation of proteins, oxidative stress, inflammation and increases plasma insulin and lipid concentrations. …”
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The Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy by Samir S. Deeb, John D. Brunzell

“…Subjects with a family history of type 2 diabetes mellitus (T2DM) were more common among those who gained excessive weight. …”
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Acorn Oil: Chemistry and Functionality by Mehdi Taib, Lahboub Bouyazza, Badiaa Lyoussi

“…Diets enriched with acorn oil can be beneficial in preventing cardiovascular disease (CVD), cancer, and type 2 diabetes as well as offer antioxidant activity. …”
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Implementation of medication management services at the primary healthcare level – a pilot study by Brajković Andrea, Mucalo Iva, Vidović Toni, Gonzaga Mariana Martins, Nascimento Do, Balenović Antonija, Protrka Ino, De Oliveira Djenane Ramalho

“…Multiple regression analysis showed that type 2 diabetic patients (p = 0.025) and patients using five or more medications (p = 0.011) should be prioritized to receive CMM services as potentially they have a higher number of DTPs, and could, therefore, obtain a greater benefit from the service.…”
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