Exercise as a Mean to Control Low-Grade Systemic Inflammation by Neha Mathur, Bente Klarlund Pedersen

“…Chronic noncommunicable diseases (CNCDs), which include cardiovascular disease, some cancers, for example, colon cancer, breast cancer, and type 2 diabetes, are reaching epidemic proportions worldwide. …”
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The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP by Mimi Gao, Roland Winter

“…Type 2 diabetes mellitus (T2DM) is an age-related and metabolic disease. …”
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The Beneficial Effects of GLP-1 Receptor Agonists Other than Their Anti-Diabetic and Anti-Obesity Properties by Chenqi Lu, Cong Xu, Jun Yang

“…GLP-1 receptor (GLP-1R) agonists are synthetic products that have similar effects to GLP-1 but are less prone to degradation, and they are widely used in the treatment of type 2 diabetes and obesity. In recent years, different beneficial effects of GLP-1R agonists were discovered, such as reducing ischemia-reperfusion injury, improving the function of various organs, alleviating substance use disorder, affecting tumorigenesis, regulating bone metabolism, changing gut microbiota composition, and prolonging graft survival. …”
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Intrauterine Growth Retardation and Nonalcoholic Fatty Liver Disease in Children by Anna Alisi, Nadia Panera, Carlo Agostoni, Valerio Nobili

“…This study suggested that, in children, adolescents, and adults born SGA, insulin resistance could lead to other metabolic disorders: type 2 diabetes (DM2), dyslipidemia, and nonalcoholic fatty liver disease (NAFLD). …”
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Lipid Chaperones and Metabolic Inflammation by Masato Furuhashi, Shutaro Ishimura, Hideki Ota, Tetsuji Miura

“…It is now clear that obesity and associated disorders such as insulin resistance and type 2 diabetes are associated with a metabolically driven, low-grade, chronic inflammatory state, referred to as “metaflammation.” …”
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Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus? by Joshua Juwono, Ryan D. Martinus

“…The focus of this review is to summarise the known relationships between the expression of heat shock protein 60 (Hsp60) and its association with the pathogenesis of Type 1 and Type 2 diabetes mellitus. Hsp60 is a mitochondrial stress protein that is induced by mitochondrial impairment. …”
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Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection by Srinivasan Lekha, Suchetha Manikandan

“…This study studies these characteristics and evaluates the behaviour of the sensor in the presence of various acetone concentrations in breath sample for healthy, type 1 and type 2 diabetic subjects.…”
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Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome by P. Stiefel, A. J. Vallejo-Vaz, S. García Morillo, J. Villar

“…Finally, overweight and obesity promote the adrenal secretion of aldosterone, increasing the predisposition to type 2 diabetes mellitus. Further studies are needed to better establish therapeutic strategies that act on the blockade of mineralocorticoid receptor in the treatment and prevention of cardiovascular diseases related to the excess of aldosterone and the metabolic syndrome.…”
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Cytokines in the Progression of Pancreatic β-Cell Dysfunction by Chunjiong Wang, Youfei Guan, Jichun Yang

“…The dysfunction of pancreatic β-cell and the reduction in β-cell mass are the decisive events in the progression of type 2 diabetes. There is increasing evidence that cytokines play important roles in the procedure of β-cell failure. …”
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The Role of SGLT2 Inhibitor on the Treatment of Diabetic Retinopathy by Wenjun Sha, Song Wen, Lin Chen, Bilin Xu, Tao Lei, Ligang Zhou

“…Sodium-dependent glucose transporter 2 inhibitor (SGLT2i) is a new antidiabetic drug which is mainly used in clinical practice to control blood glucose of patients with type 2 diabetes prone to develop chronic heart failure. …”
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Multifactorial Induction of a “Scleroderma‐Like Pattern” Without Underlying Connective Tissue Disease: Diagnostic and Therapeutic Implications by Angelo Nigro

“…A 60‐year‐old man with a significant 20‐year history of smoking, averaging approximately 20 cigarettes per day, presented with type 2 diabetes mellitus, hypercholesterolemia, and hypertension. …”
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Otyłość - ważny problem zdrowotny by Grażyna Nowicka

“…Managing of obesity and overweight is of paramount importance because of well established relations between excess body mass and different diseases such as coronary heart disease, type 2 diabetes, hypertension, and some types of cancer. …”
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An Overview of the Impact of Statin Therapy on Cardiac Incident Risk by Urszula Świrk, Aleksandra Paprocka, Karolina Kalinowska, Paulina Fijałek, Jan Karczmarz, Marika Gutowska, Agnieszka Kosińska, Wiktoria Belcarz, Joanna Orzechowska, Michał Orzechowski

“…Although generally well-tolerated, statins may cause side effects, including muscle-related symptoms and a modest increase in the risk of type 2 diabetes. Patient adherence remains a critical factor in maximizing the therapeutic benefits of statin therapy.   …”
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Enhancing Exercise Responsiveness across Prediabetes Phenotypes by Targeting Insulin Sensitivity with Nutrition by Julian M. Gaitan, Arthur Weltman, Steven K. Malin

“…Herein, we propose the novel hypothesis that the combination of individualized nutrition therapy and exercise should be based on the clinical pathology of prediabetes to overcome exercise resistance and improve responsiveness in people at risk for type 2 diabetes and cardiovascular disease.…”
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The therapeutic agents that target ATP-sensitive potassium channels by Rubaiy Hussein N.

“…ATP-sensitive potassium (KATP) channels are a major drug target for the treatment of type-2 diabetes. KATP channels are ubiquitously expressed and link the metabolic state to electrical excitability. …”
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Persistent depressive symptom trajectory is associated with cognitive impairment: a population-based longitudinal study of aging in Taiwan by Hsiao-Chen Lin, Wai-Lam Lao, Te-Chia Tseng, Chih-Jung Yeh

“…We also investigated moderating effects of sex, age, type 2 diabetes mellitus, hypertension, and coronary heart disease. …”
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Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives by Giuseppe Lopalco, Luca Cantarini, Antonio Vitale, Florenzo Iannone, Maria Grazia Anelli, Laura Andreozzi, Giovanni Lapadula, Mauro Galeazzi, Donato Rigante

“…An overview of monogenic autoinflammatory disorders, PFAPA syndrome, rheumatoid arthritis, type 2 diabetes mellitus, uveitis, pericarditis, Behçet’s disease, gout, Sjögren’s syndrome, interstitial lung diseases, and Still’s disease is presented to highlight the fundamental points that interleukin-1 displays in the cryptic interplay between innate and adaptive immune systems.…”
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Impact of Diabetes on Cardiovascular Disease: An Update by Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Roberta Arnoldi Cobas, Catia C. Sousa Palma, Carlos Antonio Negrato, Marilia de Brito Gomes

“…Cardiovascular diseases are the most prevalent cause of morbidity and mortality among patients with type 1 or type 2 diabetes. The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this population are poorly understood. …”
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Alström’s Syndrome, Leber’s Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis by Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos

“…AS affects metabolism, and symptomatology includes type 2 diabetes mellitus (T2DM), obesity, hypogonadism and gynecomastia in males, progressive bilateral sensorineural hearing loss, cardiomyopathy, nonalcoholic fatty liver disease (NAFLD), cirrhosis, and chronic progressive kidney disease. …”
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Antenatal Corticosteroids: A Risk Factor for the Development of Chronic Disease by Elizabeth Asztalos

“…However, exogenous ACS reduces birth weight which, in turn, is associated with adverse adult outcomes such as coronary heart disease, stroke, hypertension, and type 2 diabetes. The long-term effects of ACS exposure on HPA axis activity and neurological function are well documented in animal studies, and it appears that ACS, regardless of dose exposure, is capable of affecting fetal HPA axis development causing permanent changes in the HPA axis that persists through life and is manifested by chronic illness and behavioral changes. …”
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