Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil by Lawrence Coppey, Alexander Obrosov, Hanna Shevalye, Eric Davidson, William Paradee, Mark A. Yorek

“…Two of each of these groups were used to create a high-fat diet/streptozotocin model for type 2 diabetes. The remaining mice were control groups. …”
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Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study by Robert W Platt, Laurent Azoulay, Ying Cui, Christel Renoux, Oriana Hoi Yun Yu, Zarin Abdullah, Chenjie Xia

“…Objectives To assess the association between sodium-glucose co-transporter-2 inhibitor (SGLT-2i) use and the risk of incident dementia compared with dipeptidyl peptidase-4 inhibitors (DPP-4i) use among individuals with type 2 diabetes.Design A population-based retrospective cohort study.Setting The Clinical Practice Research Datalink (CPRD) Aurum database from the UK.Participants Individuals with type 2 diabetes, aged 40 years or older, newly prescribed SGLT-2i or DPP-4i on or after 2013–2021, registered in the CPRD Aurum database.Main outcome measure The primary outcome was incident dementia, and the secondary outcome was incident mild cognitive impairment (MCI). …”
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Habitual sleep duration, healthy eating, and digestive system cancer mortality by Diana A. Nôga, Elisa M. S. Meth, André P. Pacheco, Jonathan Cedernaes, Pei Xue, Christian Benedict

“…Adjusting for smoking, type 2 diabetes, and body mass index (BMI) status eliminated the association between sleep duration and digestive cancer mortality. …”
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The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes w... by Rehana Akter, Alexander Zhyvoloup, Bingqian Zheng, Surita R Bhatia, Daniel P Raleigh

“…The development of inhibitors of islet amyloid formation is important as pancreatic amyloid deposition contributes to type-2 diabetes and islet transplant failure. The Alzheimer's Aβ peptide and human amylin (h-amylin), the polypeptide responsible for amyloid formation in type-2 diabetes, share common physio-chemical features and some inhibitors of Aβ also inhibit amyloid formation by h-amylin and vice versa. …”
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DIABETES MELLITUS IN PATIENTS WITH LIVER CIRRHOSIS: NEW TREATMENT OPTIONS by L. Yu. Morgunov

“…Particular attention is paid to the development of hepatocellular insufficiency and portal hypertension in patients with cirrhosis and type 2 diabetes, as well as processes for their prevention and insulin alternative correction methods.…”
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Diabetic ketoacidosis and hyperglycemic hyperosmolar state are associated with higher in-hospital mortality and morbidity in diabetes patients hospitalized with ST-elevation myocar... by Turki Almutairi, Soha Dargham, Amin Jayyousi, Jassim Al Suwaidi, Charbel Abi Khalil

“…<h4>Background</h4>While the cardiovascular risk of hyperglycemia has been thoroughly elucidated in patients with type 2 diabetes (T2DM) hospitalized for myocardial infarction, the evidence surrounding acute severe hyperglycemia is less well-established. …”
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How Do Diabetes Models Measure Up? A Review of Diabetes Economic Models and ADA Guidelines by Lindsay Govan, Olivia Wu, Robert Lindsay, Andrew Briggs

“…Studies were included in the review if they estimated lifetime outcomes for patients with type 1 or type 2 diabetes. Only unique models, and only the original papers were included in the review. …”
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Digital interventions for self-management of prediabetes: A scoping review. by Melanie Stowell, Rosie Dobson, Katie Garner, Mirza Baig, Norma Nehren, Robyn Whittaker

“…<h4>Background</h4>Rates of prediabetes, which can lead to type 2 diabetes, are increasing worldwide. Interventions for prediabetes mainly focus on lifestyle changes to diet and exercise. …”
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Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk? by Ahmad Aljada, Kshitij Ashwin Shah, Shaker A. Mousa

“…Cardiovascular disease is a major cause of morbidity and mortality among people with type 2 diabetes mellitus. The peroxisome proliferator-activated receptor (PPAR) agonists have a significant role on glucose and fat metabolism. …”
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Reversal of the Symptoms of Diabetic Neuropathy through Correction of Vitamin D Deficiency in a Type 1 Diabetic Patient by David S. H. Bell

“…Vitamin D deficiency has been associated with both type 1 and type 2 diabetes as well as both the microvascular and macrovascular complications of diabetes. …”
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Hot pants: The emerging field of exercise mimetics, from hospital beds to the international space station by Kevin John

“…A relevant and current example of this is the enormous market demand for glucagon‐like peptide‐1 drugs for the management of obesity and type‐2 diabetes. The goal of this short review is to direct attention toward non‐pharmaceutical strategies and specifically focuses on the topical application of heat stress to passively improve health. …”
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Sleeve Gastrectomy and Gastroesophageal Reflux Disease by Michael Laffin, Johnny Chau, Richdeep S. Gill, Daniel W. Birch, Shahzeer Karmali

“…Although laparoscopic sleeve gastrectomy has been shown to be effective in producing weight loss and improving type 2 diabetes mellitus, its effect on gastroesophageal reflux disease (GERD) has been inconsistent. …”
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Physical Activity and Arterial Stiffness: A Narrative Review by Jinyu Yang, Xiaoqian Chen, Xiang Chen, Lihua Li

“…These benefits are especially significant in populations with higher cardiovascular risk, such as those with type 2 diabetes mellitus and hypertension. Therefore, maintaining an active lifestyle into older age is crucial for vascular health and may contribute to healthy aging.…”
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Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials by Vittorio Unfer, John E. Nestler, Zdravko A. Kamenov, Nikos Prapas, Fabio Facchinetti

“…Indeed, PCOS is the most common cause of anovulatory infertility in industrialized nations, and it is associated with insulin resistance, type 2 diabetes mellitus, and increased cardiovascular risk. …”
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Interorgan Crosstalk Contributing to β-Cell Dysfunction by Katsuya Tanabe, Kikuko Amo-Shiinoki, Masayuki Hatanaka, Yukio Tanizawa

“…Type 2 diabetes mellitus (T2DM) results from pancreatic β-cell failure in the setting of insulin resistance. …”
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Traditional Cardiovascular Risk Factors Associated with Diagonal Earlobe Crease (Frank Sign) in Mexican Adults: Aging, Obesity, Arterial Hypertension, and Being Male Are the Most I... by Rogelio Molina-Gallardo, Nomely S. Aurelien-Cabezas, Daniel Tiburcio-Jimenez, Jorge E. Plata-Florenzano, Jose Guzman-Esquivel, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Roque Molina-Osorio, Adrian A. De-la-Madrid-Cernas, Jorge Armando Barriguete-Melendez, Ivan Delgado-Enciso

“…Cardiovascular risk factors such as obesity, type 2 diabetes, hypertension, smoking, and dyslipidemia enfold heart disease morbimortality. …”
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Decreased Levels of Insulin-Regulated Aminopeptidase (IRAP) in Gestational Diabetes Mellitus: A Prospective Cohort Study by Osman Köse, Koray Gök, Elif Köse, Sezen Irmak Gözükara, Abdullah Tüten, Mehmet Sühha Bostancı

“…Background: Insulin-regulated aminopeptidase (IRAP) is involved in insulin sensitivity and glucose metabolism and is important in the pathophysiology of type 2 diabetes. Serum IRAP levels are strongly associated with type 2 diabetes and insulin resistance. …”
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Post Varicella Necrotising Fasciitis Afflicting Upper Limb in Young Child: A Rare Case Report by Swarup Prabhu, Ayjaz Hussain, Tarun Gupta

“…Risk factors include immunosuppression, type 2 diabetes mellitus, chronic diseases like cirrhosis of liver and chronic kidney disease, malignancies, intravenous drug use, obesity, and age more than 60 years. …”
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Cross-Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity by Anna Leonardini, Luigi Laviola, Sebastio Perrini, Annalisa Natalicchio, Francesco Giorgino

“…PPARγ activation in type 2 diabetic patients results in a marked improvement in insulin and glucose parameters, resulting from an improvement of whole-body insulin sensitivity. …”
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