Short-Term Exercise Training Improves Insulin Sensitivity but Does Not Inhibit Inflammatory Pathways in Immune Cells from Insulin-Resistant Subjects by Sara M. Reyna, Puntip Tantiwong, Eugenio Cersosimo, Ralph A. DeFronzo, Apiradee Sriwijitkamol, Nicolas Musi

“…TLR4 content and ERK phosphorylation are increased in PMNC of type 2 diabetic individuals. While exercise improves insulin sensitivity, this effect is not related to changes in TLR2/TLR4 content or ERK phosphorylation in PMNC of type 2 diabetic individuals.…”
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The Carnivore Connection Hypothesis: Revisited by Jennie C. Brand-Miller, Hayley J. Griffin, Stephen Colagiuri

“…Increasing obesity and habitual consumption of high-glycemic-load diets worsens insulin resistance and increases the risk of type 2 diabetes in all populations.…”
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Finerenone in the management of diabetes kidney disease by Parijat De, May T Khine, Andrew Frankel, Gabrielle Goldet, Debasish Banerjee, Rosa M Montero, Tahseen A Chowdhury, Damien Fogarty, Janaka Karalliedde, Ritwika Mallik, Dipesh C Patel, Mona Wahba, Peter Winocour, Sagen Zac-Varghese, Stephen Bain, Adnan Sharif, Srikanth Bellary, Indranil Dasgupta

“…Abstract People with type 2 diabetes are at risk of developing progressive diabetic kidney disease (DKD) and end stage kidney failure. …”
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Administration of RAS Inhibitor before the Onset of Diabetic Nephropathy Counteracts the Adverse Effect of Chronic Hyperglycemia and Reduces the Augmentation of Urinary Albumin Exc... by Hidenori Hirukawa, Shinji Kamei, Tomohiko Kimura, Atsushi Obata, Kenji Kohara, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto

“…We enrolled 100 subjects with type 2 diabetes who did not take any renin-angiotensin system (RAS) inhibitor. …”
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The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population by Li Jin, Tao Wang, Song Jiang, Miao Chen, Rong Zhang, Cheng Hu, Weiping Jia, Zhihong Liu

“…We aimed to investigate the association between the variant rs955333 in SCAF8-CNKSR3 and DKD susceptibility in Chinese type 2 diabetes patients. Methods. The variant rs955333 was genotyped in 1884 Chinese type 2 diabetes patients. …”
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Effects of Flash Glucose Monitoring on Dietary Variety, Physical Activity, and Self-Care Behaviors in Patients with Diabetes by Satoshi Ida, Ryutaro Kaneko, Kanako Imataka, Kaoru Okubo, Yoshitaka Shirakura, Kentaro Azuma, Ryoko Hujiwara, Hiroka Takahashi, Kazuya Murata

“…Flash glucose monitoring is a useful tool to improve physical activity in patients with type 2 diabetes.…”
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Hubungan Albuminuria dan Laju Filtrasi Glomerulus pada Pasien Diabetes Melitus Tipe 2 yang Tidak Terkontrol by Vinny Vania Parinding, Muhammad In'am Ilmiawan, Iit Fitrianingrum, Heru Fajar Trianto, Mardhia Mardhia

“…Keywords:  albuminuria, poorly controlled type 2 diabetes mellitus, glomerular filtration rate…”
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Euglycemic Ketoacidosis in a Patient with Metastatic Non-Small-Cell Lung Adenocarcinoma and Concomitant Pulmonary Embolism by Robert Sean O’Neill, Lauren Tyack, Mary Freeman, Hussein Soudy Hussein

“…We describe a case of euglycemic ketoacidosis in a patient with type 2 diabetes mellitus in the context of empagliflozin use after a recent diagnosis of metastatic lung adenocarcinoma. …”
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Prevalence of Diabetes and Prediabetes among Children Aged 11-14 Years Old in Vietnam by Duong H. Phan, Vuong V. Do, Long Q. Khuong, Hung T. Nguyen, Hoang V. Minh

“…This study is aimed at estimating the prevalence of type 1 and type 2 diabetes and prediabetes among children in Vietnam and examining factors associated with the conditions. …”
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Diabetes, TZDs, and Bone: A Review of the Clinical Evidence by Ann V. Schwartz

“…This review summarizes current findings regarding type 2 diabetes and increased fracture risk and then considers the available evidence regarding TZD use and bone metabolism in humans.…”
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Effect of Pesticides on Peroxisome Proliferator-Activated Receptors (PPARs) and Their Association with Obesity and Diabetes by J. Hernández-Valdez, A. Velázquez-Zepeda, J. C. Sánchez-Meza

“…The present review aims to show the effect of pesticides on PPARs and their contribution to the changes in energy metabolism that enable the development of obesity and type 2 diabetes mellitus.…”
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Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome by Tiziana Di Chiara, Christiano Argano, Salvatore Corrao, Rosario Scaglione, Giuseppe Licata

“…Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. …”
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Diabetes in HFE Hemochromatosis by James C. Barton, Ronald T. Acton

“…The prevalence of type 2 diabetes diagnosed today in whites of European descent with and without HFE hemochromatosis is similar. …”
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Potent Oral Hypoglycemic Agents for Microvascular Complication: Sodium-Glucose Cotransporter 2 Inhibitors for Diabetic Retinopathy by Eun Hyung Cho, Se-Jun Park, Seongwook Han, Ji Hun Song, Kihwang Lee, Yoo-Ri Chung

“…The purpose of this study was to investigate the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on the progression of diabetic retinopathy (DR) in patients with type 2 diabetes. The medical records of 21 type 2 diabetic patients who used a SGLT2i and 71 patients with sulfonylurea (control) were reviewed retrospectively. …”
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Adipokines and Hepatic Insulin Resistance by Yu Li, Lin Ding, Waseem Hassan, Daoud Abdelkader, Jing Shang

“…Obesity is a major risk factor for insulin resistance and type 2 diabetes. Adipose tissue is now considered to be an active endocrine organ that secretes various adipokines such as adiponectin, leptin, resistin, tumour necrosis factor-α, and interleukin-6. …”
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Proinflammatory Effects of C-Peptide in Different Tissues by Dusica Vasic, Daniel Walcher

“…C-peptide as a cleavage product of proinsulin is in the last few decades known as an active peptide with a number of different effects on microvascular and macrovascular complications in type 2 diabetic patients. Patients with insulin resistance and early type 2 diabetes show elevated levels of C-peptide in blood. …”
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Symptoms of Diabetes by Linda B. Bobroff

“… Type 2 diabetes is a growing health concern for children as well as adults in the United States. …”
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The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency by Ryan C. Tsou, Kendra K. Bence

“…Due to its prominent role in regulating metabolism, PTP1B is a promising therapeutic target for the treatment of human obesity and type 2 diabetes. The PTP1B protein is encoded by the PTPN1 gene on human chromosome 20q13, a region that shows linkage with insulin resistance, type 2 diabetes, and obesity in human populations. …”
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Symptoms of Diabetes by Linda B. Bobroff

“… Type 2 diabetes is a growing health concern for children as well as adults in the United States. …”
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Impaired Muscle Regeneration in Ob/ob and Db/db Mice by Mai-Huong Nguyen, Ming Cheng, Timothy J. Koh

“…In obesity and type 2 diabetes, efficient skeletal muscle repair following injury may be required, not only for restoring muscle structure and function, but also for maintaining exercise capacity and insulin sensitivity. …”
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