Metformin-Associated Acute Kidney Injury and Lactic Acidosis by David Arroyo, Rosa Melero, Nayara Panizo, Marian Goicoechea, Patrocinio Rodríguez-Benítez, Soledad García Vinuesa, Eduardo Verde, Alberto Tejedor, José Luño

“…Metformin is the preferred oral antidiabetic agent for type 2 diabetes. Lactic acidosis is described as a rare complication, usually during an acute kidney injury (AKI). …”
Get full text

Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives by Giuseppe Lopalco, Luca Cantarini, Antonio Vitale, Florenzo Iannone, Maria Grazia Anelli, Laura Andreozzi, Giovanni Lapadula, Mauro Galeazzi, Donato Rigante

“…An overview of monogenic autoinflammatory disorders, PFAPA syndrome, rheumatoid arthritis, type 2 diabetes mellitus, uveitis, pericarditis, Behçet’s disease, gout, Sjögren’s syndrome, interstitial lung diseases, and Still’s disease is presented to highlight the fundamental points that interleukin-1 displays in the cryptic interplay between innate and adaptive immune systems.…”
Get full text

Impact of Diabetes on Cardiovascular Disease: An Update by Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Roberta Arnoldi Cobas, Catia C. Sousa Palma, Carlos Antonio Negrato, Marilia de Brito Gomes

“…Cardiovascular diseases are the most prevalent cause of morbidity and mortality among patients with type 1 or type 2 diabetes. The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this population are poorly understood. …”
Get full text

Identification of Novel GCK and HNF4α Gene Variants in Japanese Pediatric Patients with Onset of Diabetes before 17 Years of Age by Rumi Katashima, Mari Matsumoto, Yuka Watanabe, Maki Moritani, Ichiro Yokota

“…Maturity-onset diabetes of the young (MODY) is commonly misdiagnosed as type 1 or type 2 diabetes. Common reasons for misdiagnosis are related to limitations in genetic testing. …”
Get full text

The Prevalence and Distribution of Vitreoretinal Interface Abnormalities among Urban Community Population in China by Lei Liu, Song Yue, Jingyang Wu, Jiahua Zhang, Jie Lian, Desheng Huang, Weiping Teng, Lei Chen

“…According to the WHO criteria, a cross-sectional study was carried out among 304 Type 2 diabetes (T2D) patients and 304 people without diabetes as control over 45 years old. …”
Get full text

Dulaglutide Protects Mice against Diabetic Sarcopenia-Mediated Muscle Injury by Inhibiting Inflammation and Regulating the Differentiation of Myoblasts by Fengyi Deng, Wenyan Wu, Xingyu Fan, Xing Zhong, Nuojin Wang, Yue Wang, Tianrong Pan, Yijun Du

“…Background. Type 2 diabetes mellitus increases the risk of sarcopenia, which is characterized by decreased muscle mass, strength, and function. …”
Get full text

Alcohol Consumption Is a Risk Factor for Lower Extremity Arterial Disease in Chinese Patients with T2DM by Shanshan Yang, Shuang Wang, Bo Yang, Jinliang Zheng, Yuping Cai, Zhengguo Yang

“…To investigate the relationship between alcohol consumption and diabetic lower extremity arterial disease (LEAD) in hospitalized patients with type 2 diabetes mellitus (T2DM). Methods. We evaluated 138 hospitalized patients with T2DM who consumed alcohol and 833 who did not. …”
Get full text

The Association between Diabetic Retinopathy and Levels of Ischemia-Modified Albumin, Total Thiol, Total Antioxidant Capacity, and Total Oxidative Stress in Serum and Aqueous Humor by Kadir Kirboga, Ayse V. Ozec, Mustafa Kosker, Ayhan Dursun, Mustafa I. Toker, Huseyin Aydin, Haydar Erdogan, Aysen Topalkara, Mustafa K. Arici

“…To investigate the oxidant and antioxidant status of patients with type 2 diabetes mellitus and nonproliferative diabetic retinopathy (DRP). …”
Get full text

Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice by Xiao Meng Zhang, Hao Deng, Jin Dong Tong, Yi Zhen Wang, Xu Chao Ning, Xiu Hong Yang, Fang Qiang Zhou, Hui Min Jin

“…We concluded that oral pyruvate delayed DN progression in db/db mice and the modified Pyr-ORS formula might be an ideal novel therapeutic drink in clinical prevention and treatment of type 2 diabetes and DN.…”
Get full text

Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications by Bou-Yue Peng, Navneet Kumar Dubey, Viraj Krishna Mishra, Feng-Chou Tsai, Rajni Dubey, Win-Ping Deng, Hong-Jian Wei

“…Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are most prevalent forms. …”
Get full text

Perceptions on Diet and Dietary Modifications during Postpartum Period Aiming at Attenuating Progression of GDM to DM: A Qualitative Study of Mothers and Health Care Workers by Thamudi D. Sundarapperuma, Champa J. Wijesinghe, Priyadarshika Hettiarachchi, Sudharshani Wasalathanthri

“…GDM mothers have a 7-fold relative risk of developing type 2 diabetes mellitus (T2DM) in their later life. User-friendly and culturally acceptable dietary interventions can minimize this risk. …”
Get full text

Mycobacterium neoaurum Bloodstream Infection Associated with a Totally Implanted Subclavian Port in an Adult with Diabetes and History of Colon Cancer by Jack E. Moseley Jr., Sharanjeet K. Thind

“…A 66-year-old male with schizophrenia, type 2 diabetes mellitus, and a history of excision and chemotherapy to treat adenocarcinoma of the colon 6 years prior, presented with fever and behavioral changes. …”
Get full text

Study on the Correlation of Skin Advanced Glycation End Products With Diabetic Cardiovascular Autonomic Neuropathy by Fang Y, Dai W, Cao Y

“…Factors affecting DCAN and those related to skin AGE accumulation in patients with DCAN were analyzed.Materials and Methods: A total of 192 patients with type 2 diabetes mellitus (T2DM) who were hospitalized in the Department of Endocrinology of Hefei Second People’s Hospital from November 2020 to December 2022 were included and divided into DCAN (n=121) and No_DCAN (n=71) groups based on the results of Ewing test. …”
Get full text

Bilateral Testicular Infarction from IgA Vasculitis of the Spermatic Cords by Mazen Toushan, Ashka Atodaria, Stephen D. Lynch, Hassan D. Kanaan, Limin Yu, Mitual B. Amin, Mamon Tahhan, Ping L. Zhang, Paul S. Kellerman, Abhishek Swami

“…A 51-year-old man with type 2 diabetes mellitus and chronic obstructive pulmonary disease presented to the emergency room with increasing bilateral leg pain, rash, and scrotal swelling with pain. …”
Get full text

Establishing Differences in Thermographic Patterns between the Various Complications in Diabetic Foot Disease by Alfred Gatt, Owen Falzon, Kevin Cassar, Christian Ellul, Kenneth P. Camilleri, Jean Gauci, Stephen Mizzi, Anabelle Mizzi, Cassandra Sturgeon, Liberato Camilleri, Nachiappan Chockalingam, Cynthia Formosa

“…To evaluate the potential of thermography as an assessment tool for the detection of foot complications by understanding the variations in temperature that occur in type 2 diabetes mellitus (DM). Methods. Participants were categorized according to a medical examination, ankle brachial index, doppler waveform analysis, and 10-gram monofilament testing into five groups: healthy adult, DM with no complications, DM with peripheral neuropathy, DM with neuroischaemia, and DM with peripheral arterial disease (PAD) groups. …”
Get full text

Рerioperative period of high-risk patients with coronary artery disease by O.K. Gogayeva

“…Among comorbid conditions, type 2 diabetes mellitus was diagnosed in 50 (25.7 %) patients, impaired glucose tolerance – in 82 (42.2 %) patients, obesity – in 74 (38.1 %) patients, 86 (44.3 %) patients were overweight with a body mass index 25–29.9 kg/m2, and 75 (38.6 %) patients were diagnosed with chronic kidney disease. …”
Get full text

Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet by Banumathi K. Cole, Margaret A. Morris, Wojciech J. Grzesik, Kendall A. Leone, Jerry L. Nadler

“…Type 2 diabetes is associated with obesity, insulin resistance, and inflammation in adipose tissue. 12/15-Lipoxygenase (12/15-LO) generates proinflammatory lipid mediators, which induce inflammation in adipose tissue. …”
Get full text

Diabetes beliefs, perceived risk and health behaviours: an embedded mixed-methods analysis from the Richmond Stress and Sugar Study by Briana Mezuk, Katherine Khosrovaneh, Viktoryia A Kalesnikava

“…The goal of this cross-sectional, embedded mixed-methods study was to examine the relationships between perceived risk, diabetes beliefs and prevention behaviours among adults at elevated risk of type 2 diabetes.Methods Data come from the Richmond Stress and Sugar Study (n=125). …”
Get full text

Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice by Wenbin Zheng, Jing Zhou, Shasha Song, Wen Kong, Wenfang Xia, Lulu Chen, Tianshu Zeng

“…Obesity and type 2 diabetes are the most common metabolic diseases globally. …”
Get full text

Healthy Chilean Adolescents with HOMA-IR ≥ 2.6 Have Increased Cardiometabolic Risk: Association with Genetic, Biological, and Environmental Factors by R. Burrows, P. Correa-Burrows, M. Reyes, E. Blanco, C. Albala, S. Gahagan

“…Family history of type 2 diabetes (FHDM) was reported. We determined the optimal cutoff of HOMA-IR to diagnose MetS (IDF criteria) using ROC analysis. …”
Get full text