Engaging with patients with diabetes: the role of social media in low-income healthcare organisations by Jose Rodriguez, Shabbir Syed-Abdul, Andrea Cano, Mohy Uddin, Fernanda Caceres

“…Background Type 2 diabetes is the fastest-growing global health concern, and its global prevalence is projected to affect 643 million individuals by 2030. …”
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Dysregulation of Metabolic Peptides in the Gut–Brain Axis Promotes Hyperinsulinemia, Obesity, and Neurodegeneration by Camille Green, Vandana Zaman, Kayce Blumenstock, Narendra L. Banik, Azizul Haque

“…The role of metabolic peptides in the development and potentially reversal of diseases such as obesity, hyperinsulinemia, and type 2 diabetes will also be discussed. Furthermore, we review the potential links between these conditions and neuroinflammation and the development of neurodegenerative diseases like dementia, specifically Parkinson’s disease and Alzheimer’s disease.…”
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Diagnostic Challenge in a Patient with Severe Anion Gap Metabolic Acidosis by Eugene M. Tan, Ejaaz Kalimullah, M. Rizwan Sohail, Kannan Ramar

“…We present a 76-year-old female with type 2 diabetes mellitus, who was found at home in a confused state. …”
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Utility of Tetrahydrobiopterin Pathway in the Assessment of Diabetic Foot Ulcer: Significant and Complex Interrelations by Marwan Al-Nimer, Rawa Ratha, Taha Mahwi

“…Tetrahydrobiopterin (BH4) pathway that included generation of neopterin (Neop), biopterin (Biop), and nitric oxide (NO) is altered in type 2 diabetes (T2D). The aim of this study was to assess the biomarkers of BH4 pathway in noninfected DFUs and to relate these levels to the variables of diabetes as well as to the hematological indices. …”
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Amylase-Dependent Regulation of Glucose Metabolism and Insulin/Glucagon Secretion in the Streptozotocin-Induced Diabetic Pig Model and in a Rat Pancreatic Beta-Cell Line, BRIN-BD11 by Kateryna Pierzynowska, Stina Oredsson, Stefan Pierzynowski

“…Blood glucose, plasma insulin, and glucagon levels were measured following a duodenal glucose tolerance test (IDGTT), in four pigs with STZ-induced type 2 diabetes (T2D pigs) and in four pigs with STZ-induced type 1 diabetes (T1D pigs). …”
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Diabetes Risk Score in a Young Student Population in Jordan: A Cross-Sectional Study by Abdel-Ellah Al-Shudifat, Amjad Al-Shdaifat, Ahmad Ali Al-Abdouh, Mohammad Ibrahim Aburoman, Sara Mohammad Otoum, Amro Ghaleb Sweedan, Ibrahim Khrais, Ibrahim Hisham Abdel-Hafez, Asgeir Johannessen

“…The Middle East is the home to the most obese population in the world, and type 2 diabetes mellitus is endemic in the region. However, little is known about risk factors for diabetes in the younger age groups. …”
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The Relationship between Cardiovascular Autonomic Dysfunction and Ocular Abnormality in Chinese T2DM by Dandan Wang, Baiyu Shen, Chunrong Wu, Yanyan Xue, Yanjun Liu

“…This study aims to explore the relationship between autonomic nerve dysfunction—assessed by cardiovascular autonomic neuropathy risk score (CAN-RS)—and ocular abnormality in Chinese type 2 diabetes mellitus (T2DM). Method. This is a cross-sectional study. …”
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Preventive interventions for diabetic foot ulcer adopted in different healthcare settings: A scoping review protocol. by Açucena Leal de Araújo, Francisca Diana da Silva Negreiros, Raquel Sampaio Florêncio, Thiago Dos Santos Garces, Virna Ribeiro Feitosa Cestari, Samuel Miranda Mattos, Samara Jesus Sena Marques, Francisca Eridan Fonteles Albuquerque, Wánderson Cássio Oliveira Araújo, Vanessa de Brito Poveda, Thereza Maria Magalhães Moreira

“…Studies with participants diagnosed with type 1 and type 2 diabetes, aged 18 years or older, without an active ulcer at baseline, and studies of preventive interventions for foot ulcers in various healthcare settings will be screened. …”
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Performance Comparison of Two Gene Set Analysis Methods for Genome-wide Association Study Results: GSA-SNP vs i-GSEA4GWAS by Ji-sun Kwon, Jihye Kim, Dougu Nam, Sangsoo Kim

“…GSA runs were made with two sets of p-values from a Korean type 2 diabetes mellitus GWAS study: 259,188 and 1,152,947 SNPs of the original and imputed genotype datasets, respectively. …”
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Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D by Sameeah Abdulrahman Rashid

“…This multicenter cross-sectional study was performed on two groups of adults (nondiabetes and type 2 diabetes) of various ages, sexes, and body mass index (BMI). …”
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Rational design, synthesis, in vitro, and in-silico studies of pyrazole‑phthalazine hybrids as new α‑glucosidase inhibitors by Mehrdad Roshan, Roghieh Mirzazadeh, Azadeh Tajmir-Riahi, Mohammad Sadegh Asgari

“…The primary aim of this study was to explore the potential of novel pyrazole-phthalazine hybrids as selective inhibitors of α-glucosidase, an enzyme involved in carbohydrate metabolism, which plays a key role in the management of type 2 diabetes. The rationale for this study stems from the need for new, more effective inhibitors of α-glucosidase with improved efficacy and safety profiles compared to currently available therapies like Acarbose. …”
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Perception of the Importance of Inherited Genetics and Lifestyle on the Development of Chronic Diseases: A UK Cross‐Sectional Survey by Aamir Hussain, Lourdes Santos‐Merx, Mariasole Da Boit

“…Moreover, the majority of the respondents chose lifestyle over inherited genes as most important factor for cancer, cardiovascular disease and Type 2 Diabetes development (50.8% vs. 29.6%, 79% vs. 11.9%, 85.7% vs. 9.6%; respectively), while 60.6% of respondents selected inherited genes for rheumatoid arthritis (p < 0.05). …”
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The Comparison of Food and Nutrient Intake among Iranian Diabetic and Non-Diabetic Adults by Najmeh Maayeshi, Hassan Mozaffari-Khosravi, Sayyed Saeid Khayyatzadeh, Hossein Fallahzadeh

“…Eating choices are considered as a main factor in type 2 diabetes (T2D) prevention and treatment. This study aimed to investigate the comparison of food and nutrient intake among diabetic and non-diabetic adults in Iran. …”
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Mild Cognitive Impairment and Depressive Symptoms in Elderly Patients with Diabetes: Prevalence, Risk Factors, and Comorbidity by Malgorzata Gorska-Ciebiada, Malgorzata Saryusz-Wolska, Maciej Ciebiada, Jerzy Loba

“…Depressive symptoms, MCI, and its comorbidity are common in elderly subjects with type 2 diabetes. Systematic screening could result in the identification of high-risk patients.…”
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Diabetic Muscle Infarction of the Tibialis Anterior and Extensor Hallucis Longus Muscles Mimicking the Malignant Soft-Tissue Tumor by Yoshikuni Mimata, Kotaro Sato, Karen Tokunaga, Itsuko Tsukimura, Hiroshi Tada, Minoru Doita

“…A 64-year-old man with type 2 diabetes mellitus presented with a 6-month history of a palpable mass in his lower left leg. …”
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Bcl-2 and Bcl-xL in Diabetes: Contributions to Endocrine Pancreas Viability and Function by Atenea A. Perez-Serna, Daniel Guzman-Llorens, Reinaldo S. Dos Santos, Laura Marroqui

“…Type 1 (T1D) and type 2 diabetes (T2D), the most common forms of diabetes, are characterized by the loss of functional pancreatic β-cells, mostly due to apoptosis. …”
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Uninephrectomy and sodium‐glucose cotransporter 2 inhibitor administration delay the onset of hyperglycemia by Yuri Sakai Ishizaki, Masao Kikuchi, Koichi Kaikita, Shouichi Fujimoto

“…Therefore, this study aimed to evaluate how each uninephrectomy (UNx) and SGLT2 inhibitor affects blood glucose concentrations and SGLTs dynamics in rats with type 2 diabetes mellitus. Male rats were divided into four treatment groups: sham + placebo, sham + dapagliflozin, UNx + placebo, and UNx + dapagliflozin. …”
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Identification of Flavonoid C-Glycosides as Promising Antidiabetics Targeting Protein Tyrosine Phosphatase 1B by Athika Rampadarath, Fatai Oladunni Balogun, Charlene Pillay, Saheed Sabiu

“…Protein tyrosine phosphatase 1B (PTP1B), a negative regulator of the insulin signaling pathway, has gained attention as a validated druggable target in the management of type 2 diabetes mellitus (T2DM). The lack of clinically approved PTP1B inhibitors has continued to prompt research in plant-derived therapeutics possibly due to their relatively lesser toxicity profiles. …”
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Metabolic Derangements Contribute to Reduced sRAGE Isoforms in Subjects with Alzheimer’s Disease by Kelly N. Z. Fuller, Edwin R. Miranda, John P. Thyfault, Jill K. Morris, Jacob M. Haus

“…Cognitively healthy elderly and AD participants with and without type 2 diabetes (n=135) were stratified according to the clinical dementia rating (CDR; 0 = normal cognition (NC); ≥0.5 = AD). …”
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Plasminogen Activator Inhibitor-1 Level Correlates with Lipoprotein Subfractions in Obese Nondiabetic Subjects by Sándor Somodi, Ildikó Seres, Hajnalka Lőrincz, Mariann Harangi, Péter Fülöp, György Paragh

“…The elevated level of plasminogen activator inhibitor-1 (PAI-1) in obese subjects with metabolic syndrome and in patients with type 2 diabetes is well established. The association of plasma PAI-1 and lipid metabolism is still unclear. …”
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