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341
Ocular changes after simultaneous kidney-pancreas transplant
Published 2022-05-01“…</i> </p> <p> <i><b>Keywords</b>: type 1 diabetes, kidney transplant, pancreas transplant, simultaneous kidney-pancreas transplant, diabetic retinopathy, diabetic macular edema.…”
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342
Association of Cardiovascular Autonomic Neuropathy and Distal Symmetric Polyneuropathy with All-Cause Mortality: A Retrospective Cohort Study
Published 2021-01-01“…In fully adjusted models, participants with type 1 diabetes patients with versus without DSPN had an increased mortality (HR 2.99, 95% CI 1.4-8.63), while no association with CAN was observed. …”
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343
Glutamine Supplementation in Sick Children: Is It Beneficial?
Published 2011-01-01“…This includes premature infants, infants with gastrointestinal disease, children with Crohn's disease, short bowel syndrome, malnutrition/diarrhea, cancer, severe burns/trauma, Duchenne muscular dystrophy, sickle cell anemia, cystic fibrosis, and type 1 diabetes. Moreover, methodological issues have been noted in some studies. …”
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344
Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets
Published 2025-01-01“…We highlight the application of immunopeptidomics in Type 1 Diabetes (T1D), Systemic Lupus Erythematosus (SLE), and Rheumatoid Arthritis (RA). …”
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345
Role of Genetic Alterations in the NLRP3 and CARD8 Genes in Health and Disease
Published 2015-01-01“…Several studies have been performed on the association of the genetic alterations in genes encoding NLRP3 and CARD8 with the complex diseases with inflammatory background, like inflammatory bowel disease, cardiovascular diseases, rheumatoid arthritis, and type 1 diabetes. The aim of the present review is therefore to summarize the literature regarding genetic alterations in these genes and their association with health and disease.…”
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346
The Histone Modification Code in the Pathogenesis of Autoimmune Diseases
Published 2017-01-01“…In this paper, we discuss the significant roles of histone modifications involved in the pathogenesis of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, primary biliary cirrhosis, and type 1 diabetes.…”
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347
The Fate of Allogeneic Pancreatic Islets following Intraportal Transplantation: Challenges and Solutions
Published 2018-01-01“…Pancreatic islet transplantation as a therapeutic option for type 1 diabetes mellitus is gaining widespread attention because this approach can restore physiological insulin secretion, minimize the risk of hypoglycemic unawareness, and reduce the risk of death due to severe hypoglycemia. …”
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348
Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols
Published 2017-01-01“…Here, we reviewed the current reprogramming of somatic cells using specific factors to induced pluripotent stem (iPS) cells capable of repairing islet β cell damage in diabetes patients to treat patients with type 1 diabetes mellitus. We also discuss the shortcomings associated with clinical use of iPS cells. …”
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349
Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics
Published 2024-01-01“…Specific genetic variants in genes that are responsible for maintaining the composition of the gut commensal, such as genes of the immune system, are described to result in gut dysbiosis that can lead to the development of several autoimmune diseases such as inflammatory bowel disease and type-1 diabetes. Similarly, the diet of an individual shapes the gut microbiota by allowing the predominance of microbes that metabolize an abundant macromolecule in the diet. …”
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350
Evolution of 𝜷-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell Transplantation
Published 2011-01-01“…Of these individuals, 5 to 10% have been diagnosed with Type 1 diabetes mellitus (T1DM), an autoimmune disease. …”
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351
A safe-enhanced fully closed-loop artificial pancreas controller based on deep reinforcement learning.
Published 2025-01-01“…Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. …”
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352
The Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy
Published 2009-01-01“…The Diabetes Control and Complications Trial (DCCT) involved intensive diabetes therapy of subjects with type 1 diabetes mellitus (T1DM) for an average period of 6.5 years. …”
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353
DKA with Severe Hypertriglyceridemia and Cerebral Edema in an Adolescent Boy: A Case Study and Review of the Literature
Published 2016-01-01“…A 13-year-old adolescent boy with type 1 diabetes mellitus (1b) presented with diabetic ketoacidosis (DKA) and cerebral edema. …”
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354
Urinary Angiotensinogen as a Biomarker of Nephropathy in Childhood
Published 2011-01-01“…Using newly developed human AGT ELISA, we measured urinary AGT levels in chronic glomerulonephritis (GN) patients and patients with type 1 diabetes in childhood. Urinary AGT level was positively correlated with diastolic blood pressure, urinary albumin, urinary protein levels, and urinary occult blood in chronic GN patients. …”
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355
Boerhaave syndrome in a paediatric patient with diabetic ketoacidosis: A case report
Published 2024-01-01“…Diabetic ketoacidosis is a serious and potentially life-threatening complication of type 1 diabetes mellitus (T1DM), which often results from poor glycaemic control. …”
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356
Genetically Engineered Islets and Alternative Sources of Insulin-Producing Cells for Treating Autoimmune Diabetes: Quo Vadis?
Published 2012-01-01“…Islet transplantation is a promising therapy for patients with type 1 diabetes that can provide moment-to-moment metabolic control of glucose and allow them to achieve insulin independence. …”
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357
Oxygenation of the Intraportally Transplanted Pancreatic Islet
Published 2016-01-01“…Intraportal islet transplantation (IT) is not widely utilized as a treatment for type 1 diabetes. Oxygenation of the intraportally transplanted islet has not been studied extensively. …”
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358
Diabetic Mastopathy: An Uncommon Complication of Diabetes Mellitus
Published 2013-01-01“…A 33-year-old woman with type 1 diabetes had excision biopsy of a 2 cm breast lump. …”
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359
JAK inhibitors: a new choice for diabetes mellitus?
Published 2025-01-01“…Recently, several clinical cases involving the reversal of type 1 diabetes mellitus (T1DM) during treatment with JAK inhibitors have been reported, and clinical studies have described the improvement of type 2 diabetes mellitus (T2DM) during treatment with JAK inhibitors. …”
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360
Long-Term Provision of Acidified Drinking Water Fails to Influence Autoimmune Diabetes and Encephalomyelitis
Published 2018-01-01“…The frequency of spontaneously occurring type 1 diabetes in female NOD mice that were maintained on acidified drinking water by the vendor did not alter after switching to neutral water in our facility. …”
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