Early Effects of Hyperbaric Oxygen on Inducible Nitric Oxide Synthase Activity/Expression in Lymphocytes of Type 1 Diabetes Patients: A Prospective Pilot Study by Ivana Resanovic, Zoran Gluvic, Bozidarka Zaric, Emina Sudar-Milovanovic, Aleksandra Jovanovic, Davorka Milacic, Radmilo Isakovic, Esma R. Isenovic

“…This study aimed at examining the early effects of hyperbaric oxygen therapy (HBOT) on inducible nitric oxide synthase (iNOS) activity/expression in lymphocytes of type 1 diabetes mellitus (T1DM) patients. A group of 19 patients (mean age: 63 ± 2.1) with T1DM and with the peripheral arterial disease were included in this study. …”
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Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas by J. Matthew Rhett, Hongjun Wang, Heather Bainbridge, Lili Song, Michael J. Yost

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Erratum to “Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes” by John E. Bylander, Faihaa Ahmed, Sabena M. Conley, Jean-Marie Mwiza, Elimelda Moige

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Association of vitamin D deficiency and insufficiency with uncontrolled type 1 diabetes Mellitus among Saudi pediatric patients; a hospital-based retrospective study by Salman Almansour, Abdullrahman Alsalamah, Mohammad Almutlaq, Ahmed Sheikh, Hamdan Z. Hamdan, Abdullah Al-Nafeesah, Ashwaq AlEed, Ishag Adam, Osama Al-Wutayd

“…BackgroundThe association between 25-hydroxy-vitamin D [25(OH)D] levels and glycemic control in pediatric patients with type 1 diabetes mellitus (T1DM) is unclear. In this study, we aimed to investigate the association between 25(OH)D levels and glycemic control in Saudi pediatric patients' with T1DM in a region that is sunny year-round.Materials and methodsA retrospective study was conducted in the Pediatric Department of King Saud Hospital in Unaizah, Saudi Arabia. …”
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Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach by Manaswini Jagadeb, V Badireenath Konkimalla, Surya Narayan Rath, Rohit Pritam Das

“…This work would be helpful for further study of the phytochemicals above for the treatment of type 1 diabetes by targeting the kir6.2 channel.…”
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Low Self-Confidence and Diabetes Mismanagement in Youth with Type 1 Diabetes Mediate the Relationship between Behavioral Problems and Elevated HbA1c by Minke M. A. Eilander, Maartje de Wit, Joost Rotteveel, Frank J. Snoek

“…Previous studies indicated an association between behavior problems (internalizing, externalizing) and glycemic control (HbA1c) in youth with type 1 diabetes (T1D). The aim of this study is to examine if this association is mediated by self-confidence and mismanagement of diabetes. …”
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LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype by Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

“…Abstract Background The complex aetiology of type 1 diabetes (T1D), characterised by a detrimental cross‐talk between the immune system and insulin‐producing beta cells, has hindered the development of effective disease‐modifying therapies. …”
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Plasma matrix metalloproteinases and tissue inhibitors of metalloproteinases explored in relation to the severity and progression of diabetic retinopathy in patients with type 1 diabetes: baseline and prospective analyses by Sven Hector, Hans Olav Thulesius, Mona Landin-Olsson, Magnus Hillman, Eva Olga Melin, Maria Thunander

“…Aims To explore whether circulating matrix metalloproteinase-2 (MMP-2), MMP-9, MMP-9/neutrophil gelatinase-associated lipocalin, MMP-9/tissue inhibitor of metalloproteinase-1 (TIMP-1), MMP-14, TIMP-2 and TIMP-3 were associated with the severity and progression of diabetic retinopathy (DR) in patients with type 1 diabetes (T1D).Methods Baseline and prospective analyses were conducted over a period of 10.5 person-years. …”
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Impact of the initiation of isCGM soon after type 1 diabetes mellitus diagnosis in adults on glycemic indices and fear of hypoglycemia: a randomized controlled trial by Jerzy Hohendorff, Jerzy Hohendorff, Agata Grzelka-Wozniak, Marta Wrobel, Michal Kania, Michal Kania, Lidia Lapinska, Dominika Rokicka, Dorota Stoltny, Irina Kowalska, Krzysztof Strojek, Dorota Zozulinska-Ziolkiewicz, Maciej T. Malecki, Maciej T. Malecki

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HLA-A02 restricted T-cell cross-reactivity to a microbial antigen by Alar Aints, Marina Šunina, Raivo Uibo

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Improving glycemic control by transitioning from the MiniMedTM 640G to 770G in Japanese adults with type 1 diabetes mellitus: a prospective, single-center, observational study by Satoshi Kubota, Ai Sato, Manami Hosokawa, Yosuke Okubo, Shohei Takayama, Atsuko Kaneko, Yasuho Shimada, Yuki Asano, Yoshihiko Sato, Masanori Yamazaki, Mitsuhisa Komatsu

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The Use of MiniMed780G System Is Associated With Stable Glycemic Control in People With Type 1 Diabetes Before, During, and After Ramadan: An Observational Study by Abdullah M. Alguwaihes, Najla Alotaibi, Metib Alotaibi, Naglaa Masry, Saher Safarini

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Exploring the Needs and Preferences of Users and Parents to Design a Mobile App to Deliver Mental Health Peer Support to Adolescents With Type 1 Diabetes: Qualitative Study by Titilola I Yakubu, Poonamdeep Jhajj, Samantha Pawer, Nicholas C West, Shazhan Amed, Tricia S Tang, Matthias Görges

“… BackgroundBeyond physical health, managing type 1 diabetes (T1D) also encompasses a psychological component, including diabetes distress, that is, the worries, fears, and frustrations associated with meeting self-care demands over the lifetime. …”
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Stable Metabolic Control but Increased Demand for Professional Support in Children with Type 1 Diabetes in the Past Ten Years in Bern/Switzerland: A Quality Control Study by Michelle J. Dennig, Grit Sommer, Tanja Zingg, Christa E. Flück, Claudia Boettcher

“…Lower HbA1c targets and increasingly complex diabetes management with substantially increasing costs dominate today’s type 1 diabetes therapy in children and adolescents. Objective. …”
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Effectiveness of the User-Centered “Healthcare CEO” App for Patients With Type 1 Diabetes Transitioning From Adolescence to Early Adulthood: Protocol for a Randomized Controlled Trial by Yueh-Tao Chiang, Hsing-Yi Yu, Pei-Kwei Tsay, Chi-Wen Chen, Chi-Wen Chang, Chien-Lung Hsu, Fu-Sung Lo, Philip Moons

“… BackgroundYoung patients aged 16 to 25 years with type 1 diabetes (T1D) often encounter challenges related to deteriorating disease control and accelerated complications. …”
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Evaluating the Effect on Total Daily Insulin Dose in Adult Patients with Type 1 Diabetes Managed with Metformin and/or GLP-1 or GLP-1/GIP Receptor Agonists by Mayeesha Ahmed, Emily Pierson, Molly Webster

“… Purpose: There are few studies that have assessed the utility of metformin and glucagon-like peptide-1 receptor agonists (GLP-1 RA) in type 1 diabetes (T1D), specifically looking at glucose control indices. …”
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Persistent Suppression of Type 1 Diabetes by a Multicomponent Vaccine Containing a Cholera Toxin B Subunit-Autoantigen Fusion Protein and Complete Freund’s Adjuvant by Béla Dénes, István Fodor, William H. R. Langridge

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Impact of ELKa, the Electronic Device for Prandial Insulin Dose Calculation, on Metabolic Control in Children and Adolescents with Type 1 Diabetes Mellitus: A Randomized Controlled Trial by Agnieszka Kowalska, Katarzyna Piechowiak, Anna Ramotowska, Agnieszka Szypowska

“…To investigate the influence of the ELKa on metabolic control in children with type 1 diabetes mellitus (T1DM). Methods. A randomized, parallel, open-label clinical trial involved 106 patients aged <18 years with T1DM, HbA1C≤10%, undergoing intensive insulin therapy, allocated to the intervention group, who used the ELKa (n=53), or the control group (n=53), who used conventional calculation methods. …”
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Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes by Leslie P. Cousens, Yan Su, Elizabeth McClaine, Xin Li, Frances Terry, Robert Smith, Jinhee Lee, William Martin, David W. Scott, Anne S. De Groot

“…Here we evaluate their impact on human immune responses to islet cell antigens ex vivo and on the modulation of type 1 diabetes (T1D) in a murine model in vivo. Co-administration of Tregitopes and T1D antigens delayed development of hyperglycemia and reduced the incidence of diabetes in NOD mice. …”
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Ethnic disparities in HbA1c and hypoglycemia among youth with type 1 diabetes: beyond access to technology, social deprivation and mean blood glucose by Suma Uday, John Stuart Pemberton, Zhide Fang, Stuart A Chalew

“…Introduction The UK national pediatric diabetes audit reports higher HbA1c for children and young people (CYP) with type 1 diabetes (T1D) of Black ethnicity compared with White counterparts. …”
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