Evaluation of the Potential Prognostic Value of Tumor Budding in Laryngeal Carcinoma by Conventional and Immunohistochemical Staining by Nermine M. Abd Raboh, Ossama M. Mady, Sarah A. Hakim

“…Background. Tumor budding is a promising prognostic indicator in several cancers especially in colorectal cancer. …”
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G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz

“…Finally, our results provide the first demonstration that pharmacological inhibition of GPER activity in vivo prevents estrogen-mediated tumor growth.…”
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Revolutionizing ESCC prognosis: the efficiency of tumor-infiltrating immune cells (TIIC) signature score by Haixia Wang, Shaowei Ma, Zixin Yang, Ren Niu, Haiyong Zhu, Shujun Li, Shaolin Gao, Zhirong Li, Yanhua Tian

Subjects: “…Tumor-infiltrating immune cells (TIIC)…”
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Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report by Zamin Adigozalli, Rasim Khalilov, Steffen Seyfried

Subjects: “…gastrointestinal stromal tumor…”
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Gastric Carcinoma with Osteoclast-Like Giant Cells Coexisting with Gastrointestinal Spindle Cell Tumor by Christos Poulios, Triantafyllia Koletsa, Antonis Goulas, Georgia Karayannopoulou, Eleni Vrettou, Ioannis Kostopoulos

“…Sections from the tumor showed gastric adenocarcinoma, stage pT1bpN0. …”
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The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity by Mustafa Sibai, Sergi Cervilla, Daniela Grases, Eva Musulen, Rossana Lazcano, Chia-Kuei Mo, Veronica Davalos, Arola Fortian, Adrià Bernat, Margarita Romeo, Collin Tokheim, Jordi Barretina, Alexander J. Lazar, Li Ding, Enrique Grande, Francisco X. Real, Manel Esteller, Matthew H. Bailey, Eduard Porta-Pardo, Enrique Grande, Teresa Alonso-Gordoa, Mario Álvarez-Maestro, Elena Andrada, Ainara Azueta, Raquel Benítez Javier Burgos, Daniel Castellano, M. Angel Climent, Mario Domínguez, Ignacio Durán Albert Font, Isabel Galante, Patricia Galván, Juan F. García, Xavier García del Muro, Félix Guerrero-Ramos, Núria Malats, Miriam Marqués, Pablo Maroto, Jaime Martínez de Villarreal, Ane Moreno-Oya, Jesús M. Paramio, Alvaro Pinto, Aleix Prat, Javier Puente, Oscar Reig, Francisco X. Real

“…Summary: Tumors are complex ecosystems of interacting cell types. …”
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Tracking Tumor Cells in Lymphatics in a Mice Xenograft Model by Magnetic Resonance Imaging by Ting Liu, Haijun Zhou, Rui Xia, Jichun Liao, Changqiang Wu, Hui Wang, Hua Ai, Feng Bi, Fabao Gao

“…To enrich our understanding of the mechanism of tumor lymphatic metastasis, we developed a model system for tracking metastatic tumor cells in the lymphatic system with cellular magnetic resonance imaging (MRI) in live mice to observe the interaction between tumor cells and the lymphatic system. …”
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Supra-Acetabular Brown Tumor due to Primary Hyperparathyroidism Associated with Chronic Renal Failure by Rosaria M. Ruggeri, Emanuele Calamoneri, Antonia Russo, Alessandro Sindoni, Baldassarre Mondello, Maurizio Monaco, Michele A. Rosa, Sergio Baldari, Salvatore Benvenga, Alfredo Campennì, Francesco Trimarchi

“…This case is noteworthy because (1) primary hyperparathyroidism was not suspected due to the normocalcemia, likely attributable to the coexistence of chronic renal failure; and (2) it was associated with a brown tumor of unusual location (right supra-acetabular region).…”
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A Patient with Advanced Gastric Cancer Presenting with Extremely Large Uterine Fibroid Tumor by Kwang-Kuk Park, Song-I Yang

“…Introduction. Uterine fibroid tumors (uterine leiomyomas) are the most common benign uterine tumors. …”
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Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy by Amelia C. McCue, Stephen J. Demarest, Karen J. Froning, Michael J. Hickey, Stephen Antonysamy, Brian Kuhlman

“…The toxicity of TCEs may be ameliorated through the use of pro-drug forms of the TCE, which are not fully functional until recruited to the tumor microenvironment. This can be accomplished by masking the anti-CD3 arm of the TCE with an autoinhibitory motif that is released by tumor-enriched proteases. …”
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Evaluation of Tumor Heterogeneity of Prostate Carcinoma by Flow- and Image DNA Cytometry and Histopathological Grading by Naining Wang, Claudia Wilkin, Alfred Böcking, Bernhard Tribukait

“…Heterogeneity of prostate carcinoma is one of the reasons for pretreatment underestimation of tumor aggressiveness. We studied tumor heterogeneity and the probability of finding the highest tumor grade and DNA aneuploidy with relation to the number of biopsies. …”
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Occupational Neurobrucellosis Mimicking a Brain Tumor: A Case Report and Review of the Literature by Hussein Algahtani, Bader Shirah, Dina Abdulghani, Roiya Farhan, Raghad Algahtani

“…Neurobrucellosis should be included in the differential diagnosis in patients presenting with solitary mass lesion mimicking brain tumor especially in endemic areas or high occupational risk group.…”
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Expression of CD68+ Tumor associated macrophages in relation to β-catenin in carcinoma stomach by Nikhil Sharma, Ranjita Panigrahi, Prita Pradhan, Sabyasachi Parida, Saroj R. Sahoo

“…TAM density was qualitatively compared in “tumor” versus “stroma” and “tumor” versus “non-tumor” regions. …”
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Circulating tumor DNA as a therapeutic approach for HPV (+) oropharyngeal squamous cell carcinoma by Raghul Murugan

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Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations by Alireza Shadab, Simin Farokhi, Arshia Fakouri, Neda Mohagheghzadeh, Ali Noroozi, Zahra Sadat Razavi, Arian Karimi Rouzbahani, Hamidreza Zalpoor, Mohamad Mahjoor

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Non-cirrhotic Splenic-portal Thrombosis, non-tumoral Polycitemia Vera: an Infrequent Association by Samuel Sánchez Sánchez, Karina Rivero García, Osvaldo Rodríguez Morales, René Rivero Rodríguez

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APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage by Xiaojing Wang, Keisuke Ishimatsu, Junjie Li, Xiaodong Wen, Weijun Ou, Arnida Anwar, Jaideep Chaudhary, Masaya Takahashi, A Dean Sherry, Ian R Corbin

“…Intra-arterial administration of low-density lipoprotein docosahexaenoic acid (LDL-DHA) nanoparticles to N1S1 xenografts rapidly lowered the tumor APTw signal within 72 h. Direct injections of LDL-DHA nanoparticles into HepG2 xenografts also showed similar therapeutic responses.Conclusion: We have demonstrated the utility of APTw imaging in the diagnostic/therapeutic management of HCC.…”
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The Application of Convolutional Neural Network Combined with Fuzzy Algorithm in Colorectal Endoscopy for Tumor Assessment by Te-Jen Su, Feng-Chun Lee, Cheuk-Kwan Sun, Fu-Xiang Ke, Shih-Ming Wang, Ming-Chih Huang

“…In this study, the convolutional neural network was used to assess the risk of tumor in the colon by colonoscopy. The endoscopic images of the colon, which were classified into three categories of healthy (normal), benign tumor, and malignant tumor, were adopted as training data. …”
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KRAS Mutation in Serous Borderline Tumor of the Testis: Report of a Case and Review of the Literature by Sarah Bouri, Jean-Christophe Noël, Xavier Catteau, Walid Al Hajj Obeid, Ilyas Svistakov, Thierry Roumeguère, Nicky D’Haene, Sandrine Rorive

“…Ovarian-like epithelial tumors of the testis, including serous borderline tumors, are rare entities. …”
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Quality of Pancreatic Neuroendocrine Tumor Videos Available on TikTok and Bilibili: Content Analysis by Zheyu Niu, Yijie Hao, Faji Yang, Qirong Jiang, Yupeng Jiang, Shizhe Zhang, Xie Song, Hong Chang, Xu Zhou, Huaqiang Zhu, Hengjun Gao, Jun Lu

“…However, it remains uncertain whether pancreatic neuroendocrine tumor (pNET)-related videos available on current short video platforms can effectively convey accurate and impactful information to the general public. …”
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