Outcomes of oncologic arthroplasty in children and adolescents with malignant limb tumors: a systematic review by Vyacheslav I. Zorin, Sergei V. Vissarionov, Alexandr Y. Makarov, Timofey S. Rybinskikh, Kristina N. Rodionova

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P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors by Marjory Alana Marcello, Elaine Cristina Morari, Lucas Leite Cunha, Aline Carolina De Nadai Silva, Dirce Maria Carraro, André Lopes Carvalho, Fernando Augusto Soares, José Vassallo, Laura Sterian Ward

“…ACIS-III system was used to evaluate p53 and immune cell markers including tumor-associated macrophages (TAM); CD68 and tumor-infiltrating lymphocytes (TIL) subsets such as CD3, CD4, CD8, and CD20 in 206 thyroid carcinomas, 105 benign nodules, and 18 normal tissues. …”
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Fully automated segmentation and classification of renal tumors on CT scans via machine learning by Jang Hee Han, Byung Woo Kim, Taek Min Kim, Ji Yeon Ko, Seung Jae Choi, Minho Kang, Sang Youn Kim, Jeong Yeon Cho, Ja Hyeon Ku, Cheol Kwak, Young-Gon Kim, Chang Wook Jeong

“…Renal tumor masks manually drawn on contrast-enhanced CT images were used to develop a 3D U-Net-based deep learning model for fully automated tumor segmentation. …”
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PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors by Francesco Dituri, Antonio Mazzocca, Gianluigi Giannelli, Salvatore Antonaci

“…The immunological surveillance of tumors relies on a specific recognition of cancer cells and their associate antigens by leucocytes of innate and adaptive immune responses. …”
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Super-enhancers in tumors: unraveling recent advances in their role in Oncogenesis and the emergence of targeted therapies by Yumeng Ji, Baixue Li, Rongjin Lin, Jing Yuan, Yang Han, Yuping Du, Yang Zhao

“…Abstract Super enhancers are a unique class of enhancers that possess a distinct structure and mechanism, which enable them to exhibit stronger gene transcription regulatory function than classical enhancers, thereby regulating cellular activities. In tumor samples, super enhancers have been identified as crucial players in the development and progression of tumor cells, opening up new avenues for cancer research and treatment. …”
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The Role of HLA-Class Ib Molecules in Immune-Related Diseases, Tumors, and Infections 2016 by Roberta Rizzo, Enrico Fainardi, Nathalie Rouas-Freiss, Fabio Morandi

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Radiological and Clinical Features and Outcomes of Patients with Primary Pulmonary Salivary Gland-Type Tumors by Xiaoyu Han, Jianchu Zhang, Jun Fan, Yukun Cao, Jin Gu, Heshui Shi

“…To analyze the radiological, clinical, and prognostic features of primary pulmonary salivary gland-type tumors (SGTs) and improve their diagnosis. Materials and Methods. …”
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Lipid metabolic remodeling delays senescence of T cells to potentiate their immunity against solid tumors by Lu Wang, Li Ding, Gang Chen, Zhou Xu, Yanqing Zhang, Bin Deng, Xiya Wang, Yemin Xu, Mengyue Wu, Yinhe Xia, Zhennan Cao, Ruilong Song

“…Background Tumor cells can drive the senescence of effector T cells by unbalancing their lipid metabolism, thereby limiting adoptive T cell therapy and contributing to tumor immune evasion. …”
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Short-term results of treatment of non-epithelial gastro-intestinal tumors complicated by bleeding by S. G. Shapovalyants, A. I. Mikhalev, Ye. D. Fedorov, R. V. Plakhov, L. M. Mikhaleva, Z. V. Galkova, Ye. V. Ivanova, A. E. Sergeyenko

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Reporting and representation of participant race and ethnicity in phase III clinical trials for solid tumors by Tianyi Wang, Dinorah J Villanueva, Ambily Banerjee, Dina Gifkins

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Reevaluating the Concept of Treating Experimental Tumors with a Mixed Bacterial Vaccine: Coley’s Toxin by C. Maletzki, U. Klier, W. Obst, B. Kreikemeyer, M. Linnebacher

“…In vivo, repetitive, local CT application was well tolerated by animals and induced considerable delay of Panc02 tumors. However, systemic treatment failed to affect tumor growth. …”
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Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors by G. Lamberti, C. Ceccarelli, N. Brighi, I. Maggio, D. Santini, C. Mosconi, C. Ricci, G. Biasco, D. Campana

“…To evaluate the role of the activation of mTOR (phosphorylated mTOR, p-mTOR) and the expression SSTR2A and IGF-1R as prognostic factor in well-differentiated neuroendocrine tumors. Methods. A retrospective study was conducted on data from patients with diagnosis of neuroendocrine tumor originated from pancreas (pNET) or gastrointestinal tract (stomach, appendix, and ileus; GI-NET) made between January 2003 and December 2004 and followed up at our institution. …”
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Accurate identification of primary site in tumors of unknown origin (TUO) using DNA methylation by Drew Duckett, Erica R. Vormittag-Nocito, Pouya Jamshidi, Madina Sukhanova, Stephanie Parker, Daniel J. Brat, Lawrence J. Jennings, Lucas Santana-Santos

“…Abstract Tumors of unknown origin (TUO) generally result in poor patient survival and are clinically difficult to address. …”
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Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors by Song Li, Yunheng Liu, Xiaokang Zhang, Yurong Liu, Longqing Si, Shaojing Jiang, Aoya Wang, Xukai Che, Jing Chen, Jinghui Hu

“…Furthermore, the myeloid-derived suppressor cells in the tumor decreases significantly after treatment. In summary, this multi-pathway oxidative stress-amplified targeted nanosystem effectively inhibits tumors, reverses the immunosuppressive tumor microenvironment, and provides new insights into tumor immunotherapy combined with phototherapy.…”
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Canine Mammary Tumors as a Potential Model for Human Breast Cancer in Comparative Oncology by Amirhossein Razavirad, Sanaz Rismanchi, Pejman Mortazavi, Ahad Muhammadnejad

“…Clinical and molecular similarities between canine mammary tumors (CMTs) and human breast cancer (HBC) propel scientists to further study their application in comparative oncology as a model for human breast cancer. …”
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Divergent Crosstalk Between Microglia and T Cells in Brain Cancers: Implications for Novel Therapeutic Strategies by Min-Hee Yi, Jinkyung Lee, Subin Moon, EunA So, Geonhyeok Bang, Kyung-Sub Moon, Kyung-Hwa Lee

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Management of thyroid tumors diagnosed cytologically as follicular neoplasms in a high-volume center: utility of a scoring system using serum thyroglobulin level, tumor size, ultrasound testing, and cytological diagnosis by Yasuhiro Ito, Makoto Kawakami, Mitsuyoshi Hirokawa, Masashi Yamamoto, Minoru Kihara, Naoyoshi Onoda, Akihiro Miya, Akira Miyauchi, Takashi Akamizu

Subjects: “…follicular thyroid tumor…”
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Human Umbilical Cord Perivascular Cells Prevent Tumor Growth in a Melanoma Tumor-Bearing Mouse Model and Modulate Breast Cancer and Melanoma Cells in a Cell Line-Dependent Manner In Vitro by Lianet Lopez, Hannah Shuster-Hyman, Eden Marco, Hasna Khan, Avishai Gasner, Aleksandra Uzelac, Brandon Wyse, Poonam Mander, Mugundhine Sangaralingam, Joseph Fish, Ariel Gorodensky, Samar Mouazz, Amanda Kauffman, Denis Gallagher, Andrée Gauthier-Fisher, Clifford L. Librach

“…This study was designed to determine if human umbilical cord perivascular cells modulate tumor growth when injected systemically in a tumor-bearing mouse model. …”
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Insulinomas: Comprehensive Review of Epidemiology, Pathophysiology, Clinical Manifestations, Diagnostic Approaches, and Treatment Options by Joanna Rychlewska-Duda, Justyna Lisiecka, Mateusz Janik, Barbara Ufnalska, Anna Konarska, Artur Fabijański, Anna Machowiak, Michał Nowak, Wojciech Firlej, Adriana Daria Dukacz

Subjects: “…pancreatic neuroendocrine tumors (PNETs)…”
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Unveiling the Enigma of Cutaneous Adnexal Tumors: A 2-year Clinicopathological Study in a Tertiary Care Center of the Sub-Himalayan Region by Anchana Gulati, Mudita Gupta, Digvijay Dattal

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