Differentiating low- and high-proliferative soft tissue sarcomas using conventional imaging features and radiomics on MRI by Fabian Schmitz, Hendrik Voigtländer, Dimitrios Strauss, Heinz-Peter Schlemmer, Hans-Ulrich Kauczor, Hyungseok Jang, Sam Sedaghat

“…Abstract Background Soft-tissue sarcomas are rare tumors of the soft tissue. Recent diagnostic studies mainly dealt with conventional image analysis and included only a few cases. …”
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Essential Oils from Citrus Peels Promote Calcium Overload-Induced Calcicoptosis in U251 Cells by Yurong Li, Juanjuan Wei, Zimao Ye, Chen Ji, Wenji Li, Li Xu, Zhiqin Zhou

“…Additionally, the activation of calcicoptosis-related indicators induced by the CPEOs could be reversed by inhibitor treatment, confirming that both of the selected CPEOs inhibit tumors by activating calcicoptosis-related pathways. …”
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Treatment of metastatic brain lesion by A. M. Zaytsev, M. I. Kurzhupov, E. A. Potapova, O. N. Kirsanova

“…To control the radical removal of the tumor in 93 (34,7%) patients we used the method of fluorescence navigation (FN) with the drug Alasens. …”
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Long-Term Clinical Outcomes of Invasive Giant Prolactinomas after a Mean Ten-Year Followup by Ze Rui Wu, Yong Zhang, Lin Cai, Shao Jian Lin, Zhi Peng Su, Yong Xu Wei, Han Bing Shang, Wen Lei Yang, Wei Guo Zhao, Zhe Bao Wu

“…After a mean follow-up period of 135.5±4.7 months, the clinical symptoms in all patients improved by different degrees. Tumor volume was decreased by a mean of 98.6%, and the tumors of 19 patients had almost completely disappeared. …”
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A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights by Ridwan S, Harsono AB, Suardi D, Kurniadi A, Mantilidewi KI, Hidayat YM

“…Distant metastasis often occurs decades after the primary tumor, with the most common metastatic sites being the lungs and bones. …”
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Impact of postoperative morbidity on the prognosis of patients with hepatocellular carcinoma after laparoscopic liver resection: a multicenter observational study by Shiye Yang, Haishun Ni, Aixian Zhang, Jixiang Zhang, Hong Zang, Zhibing Ming

“…Diabetes mellitus, cirrhosis, portal hypertension, Child-Pugh grade B, multiple tumors, poor tumor differentiation and intraoperative blood transfusion were risk factors of postoperative morbidity. …”
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Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels by Nathalie Idlin, Sivakumar Krishnamoorthy, Magdalena Wolczyk, Mouad Fakhri, Michal Lechowski, Natalia Stec, Jacek Milek, Pratik Kumar Mandal, Jaroslaw Cendrowski, Christos Spanos, Magdalena Dziembowska, Katarzyna Mleczko-Sanecka, Juri Rappsilber, Gracjan Michlewski

“…Additionally, HuR inhibition reduces the levels of glycoprotein hormones, alpha polypeptide (CGA), a marker associated with hormone-induced tumors, suggesting a potential use of Eltrombopag in treatment of cancers overexpressing CGA. …”
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Analysis of diagnostic genes and molecular mechanisms of Crohn’s disease and colon cancer based on machine learning algorithms by Jie Xiao, Junyao Liang, Tao Zhou, Man Zhou, Dexu Zhang, Hui Feng, Chusen Tang, Qian Zhou, Weiqing Yang, Xiaoqin Tan, Wanjia Zhang, Yin Xu

“…Abstract Crohn’s disease (CD) is a chronic inflammatory bowel condition, and colon adenocarcinoma (COAD), as one of the most prevalent malignant tumors of the digestive tract, has been indicated by research to have a close association with CD. …”
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Evaluation of the Expression of the Human Epithelial Receptor 2 (HER2) in Gastric Carcinoma by Roberto de Moraes Cordts Filho, Paulo Kassab, Laura Carolina Lopez Claro, Mabel Tatty de Medeiros Fracassi, Patrícia Colombo-Souza, Daniel Kenji Fukuhara, Fábio Rodrigues Thuler, Wilson Rodrigues de Freitas Junior, Elias Jirjoss Ilias, Carlos Alberto Malheiros

“…A retrospective analysis was conducted from January of 2008 to July of 2012, considering only gastrectomies with curative intent. Tumors were tested for HER2 status using immunohistochemistry. …”
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Effect of diabetes mellitus on levels of insulin-like growth factors and their carrier proteins in Guerin’s carcinoma and it’s perifocal tissue in rats by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, N. D. Cheryarina, P. S. Kachesova, L. A. Nemashkalova

“…DM in females upregulated levels of glucose both in the tumor and in perifocal tissues by 1.8 (p < 0.05) and 8.1 times, respectively, but caused opposite changes in IGF-I - it's increase by 6.3 times in the tumor and decrease by 3.2 times in the perifocal area; as a result, such tumors with small primary nodes were more "aggressive" and actively metastasized. …”
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The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma by Wu Y, Zhu J, Zhang H, Xia N

“…As per the Revised Evaluation Criteria for Clinical Efficacy in Solid Tumors (mRECIST) criteria, the objective remission rate in Group A was significantly higher than that in Group B (86.6% vs 33.4%). …”
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Toward Robust Lung Cancer Diagnosis: Integrating Multiple CT Datasets, Curriculum Learning, and Explainable AI by Amira Bouamrane, Makhlouf Derdour, Akram Bennour, Taiseer Abdalla Elfadil Eisa, Abdel-Hamid M. Emara, Mohammed Al-Sarem, Neesrin Ali Kurdi

“…<b>Background and Objectives:</b> Computer-aided diagnostic systems have achieved remarkable success in the medical field, particularly in diagnosing malignant tumors, and have done so at a rapid pace. However, the generalizability of the results remains a challenge for researchers and decreases the credibility of these models, which represents a point of criticism by physicians and specialists, especially given the sensitivity of the field. …”
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Application of Dynamic 18F-FDG PET/CT for Distinguishing Intrapulmonary Metastases from Synchronous Multiple Primary Lung Cancer by Weize Lv, Min Yang, Hongcheng Zhong, Xiaojin Wang, Shuai Yang, Lei Bi, Jianzhong Xian, Xiaofeng Pei, Xinghua He, Ying Wang, Zhong Lin, Qingdong Cao, Hongjun Jin, Hong Shan

“…The SUVmax, fitted Ki value based on dynamic scanning, and corresponding maximum diameter (Dmax) from the two largest tumors were determined in each patient. We determined the absolute between-tumor difference of SUVmax/Dmax and Ki/Dmax (ΔSUVmax/Dmax; ΔKi/Dmax) and assessed the between-group differences. …”
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The safety and efficacy of immune checkpoint blockade in children, adolescents, and young adults: A systematic review and meta-analysis by Pedro C.A. Reis, João Evangelista Ponte Conrado, Mariana Macambira Noronha, Luís Felipe Leite da Silva, Erick Figueiredo Saldanha, Jonathan Metts

“…All-grade TRAE rate of 66 % was found (95 % CI 60–71), while the proportion of grade 3/4 TRAEs was 19 % (95 % CI 14–27). For tumor type subgroup analysis of all-grade TRAEs and grade 3/4 TRAEs, solid tumors had the highest rates, 92 % (95 % CI 41–99) and 32 % (95 % CI 11–63), respectively. …”
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Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review by Francesco M Marincola, Alessandra Cesano, Yana G Najjar, Davide Bedognetti, Marco Ruella, Sarah Warren, Christine Spencer, Elad Ziv, Tomas Kirchhoff, Jennifer McQuade, Tullia C Bruno, Jakob Nikolas Kather, Allison Betof Warner, Christian Hammer, Alberto Carturan, Ryan Augustin, Rhine Shen, Winson S Ho, Rongze O Lu, Luigi Barrea, Violena Pietrobon, Laura Soldati

“…Cancer immunotherapy—including immune checkpoint inhibition (ICI) and adoptive cell therapy (ACT)—has become a standard, potentially curative treatment for a subset of advanced solid and liquid tumors. However, most patients with cancer do not benefit from the rapidly evolving improvements in the understanding of principal mechanisms determining cancer immune responsiveness (CIR); including patient-specific genetically determined and acquired factors, as well as intrinsic cancer cell biology. …”
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Development and assessment of a mortality risk prediction nomogram model for pneumocystis disease in ICU within 28 days by Yiru Weng, Tingting Zhou, Honghua Ye

“…Five variables—the history of malignant tumors, Lods scores, Oasis scores, and complications of shock and severe renal injury—were eventually included in the entire sample after screening. …”
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Investigating the Role of Osteopontin (OPN) in the Progression of Breast, Prostate, Renal and Skin Cancers by Gautam Kundu, Selvakumar Elangovan

“…<b>Background/Objectives</b>: Cancer is caused by disruptions in the homeostatic state of normal cells, which results in dysregulation of the cell cycle, and uncontrolled growth and proliferation in affected cells to form tumors. Successful development of tumorous cells proceeds through the activation of pathways promoting cell development and functionality, as well as the suppression of immune signaling pathways; thereby providing these cells with proliferative advantages, which subsequently metastasize into surrounding tissues. …”
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Adipose-Derived Mesenchymal Stem Cell Exosomes Suppress Hepatocellular Carcinoma Growth in a Rat Model: Apparent Diffusion Coefficient, Natural Killer T-Cell Responses, and Histopa... by Sheung-Fat Ko, Hon-Kan Yip, Yen-Yi Zhen, Chen-Chang Lee, Chia-Chang Lee, Chung-Cheng Huang, Shu-Hang Ng, Jui-Wei Lin

“…The exosome-treated rats showed partial but nonsignificant tumor reduction, and significant ADC and ADC ratio increases on day 10. …”
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Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p by Lu Wang, ShuangQing Li, Lin Qi, Lin Ling

“…Western blot was performed to detect the mitotic markers and apoptosis-related proteins. A nude mouse tumor formation experiment was used to evaluate osteosarcoma progression in vivo. …”
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Diagnostic efficacy and necessity of 18F-FDG PET/CT in fever of unknown origin: insights from a retrospective cohort study by Xiaoman Yu, Shuang Wang, Na Du, Hongguang Zhao, Haiying Chen

“…The diagnostic performance for different etiologies of FUO was assessed by calculating the area under the receiver operating characteristic curve.ResultsOf the 284 enrolled patients, infectious diseases were diagnosed in 53 (18.7%), non-infectious inflammatory diseases in 76 (26.8%), malignant tumors in 66 (23.2%), and 89 (31.3%) remained undiagnosed. …”
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