Prognostic Value of STMN1 Expression in Non-small Cell Lung Cancer: 
A Meta-analysis by Mengjie LI, Qinghua ZHOU

“…Background and objective Lung cancer is one of the malignant tumors with the highest morbidity and mortality rates worldwide, seriously threatening human health. …”
Get full text

GPR176 Is a Biomarker for Predicting Prognosis and Immune Infiltration in Stomach Adenocarcinoma by Lin Ni, Shuming Chen, Jianyong Liu, He Li, Hu Zhao, Chunhua Zheng, Yawei Zhang, Hancong Huang, Junjie Huang, Bing Wang, Chengzhi Lin

“…It is believed that the poor therapeutic efficacy is attributed to the complex tumor immune microenvironment (TIM) of STAD. Therefore, elucidating the specific regulatory mechanism of TIM in STAD is critical. …”
Get full text

Development of a Ten-lncRNA Signature Prognostic Model for Breast Cancer Survival: A Study with the TCGA Database by Wenqing Zhou, Yongkui Pang, Yunmin Yao, Huiying Qiao

“…Long noncoding RNA (lncRNA) plays a critical role in the development of tumors. The aim of our study was construction of a lncRNA signature model to predict breast cancer (BRCA) patient survival. …”
Get full text

The Principal of Dynamic Contrast Enhanced MRI, the Method of Pharmacokinetic Analysis, and Its Application in the Head and Neck Region by Toru Chikui, Makoto Obara, Arjan W. Simonetti, Masahiro Ohga, Shoichi Koga, Shintaro Kawano, Yoshio Matsuo, Takeshi Kamintani, Tomoko Shiraishi, Erina Kitamoto, Katsumasa Nakamura, Kazunori Yoshiura

“…Many researchers have established the utility of the dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) in the differential diagnosis in the head and neck region, especially in the salivary gland tumors. The subjective assessment of the pattern of the time-intensity curve (TIC) or the simple quantification of the TIC, such as the time to peak enhancement () and the wash-out ratio (WR), is commonly used. …”
Get full text

Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy by Margrete Haram, Rune Hansen, Ola Finneng Myhre, Stian Solberg, Naseh Amini, Bjørn Atle Angelsen, Catharina de Lange Davies, Eva Hofsli

“…Objective: Preclinical trials have demonstrated promising results for increased tumor uptake and therapeutic effect of drugs combined with focused ultrasound (FUS) and microbubbles (MBs). …”
Get full text

An Electrosurgical Endoknife with a Water-Jet Function (Flushknife) Proves Its Merits in Colorectal Endoscopic Submucosal Dissection Especially for the Cases Which Should Be Remove... by Yoji Takeuchi, Toshio Shimokawa, Ryu Ishihara, Hiroyasu Iishi, Noboru Hanaoka, Koji Higashino, Noriya Uedo

“…The differences of operation time between the Flexknife and the Flushknife groups in each subgroup (tumor size, location, and macroscopic type) were analyzed. …”
Get full text

Salidroside enhances 5-fluorouracil sensitivity against hepatocellular carcinoma via YIPF5-induced mitophagy by Sumin Sun, Haili Hu, Feiyu Li, Feiyu Li, Sheng Huan, Long Chen, Jiahui Chen, Peihua Sun, Xiaoqing Dong, Xiaoqing Dong

“…Hepatocellular carcinoma (HCC) is a major medical challenge due to its high incidence and poor prognosis. 5-Fluorouracil (5-FU), although extensively studied in the treatment of HCC and other solid tumors, has limited application as a first-line therapy for HCC due to its resistance and significant inter-patient variability. …”
Get full text

Endoscopic Analysis of Microstructures of the Colon Mucosa on the Edge of the Post-Resection Defect as a Measure of Preventing Recurrence of Polyps after a Cold Polypectomy by N. V. Ageykina, N. A. Oleynikova, P. G. Malkov, N. V. Danilova, O. A. Kharlova, Yu. M. Korolev, E. D. Fedorov

“…Тhis research helps to ensure reliable diagnosis of the completeness of performed endoscopic intervention and the possibility of removal of residual tumor tissue (if present) immediately after its completion, it’s allow a reduction in the number of recurrences of tumors.…”
Get full text

Pilot Trial on Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer: Feasibility and Impact on Anastomotic Leakage (TIGOAL-I) by María-Carmen Fernández-Moreno, MD, PhD, María Eugenia Barrios Carvajal, MD, Fernando López Mozos, MD, PhD, Roberto Martí Obiol, MD, PhD, Jorge Guijarro Rozalén, MD, PhD, Elisabetta Casula, MD, PhD, Joaquín Ortega, MD, PhD

“…Eligible patients with resectable malignant esophageal tumors, suitable for cervical esophagogastrostomy, were randomized into 2 groups: one receiving PAE and the other standard treatment. …”
Get full text

N6-methyladenosine-modification of USP15 regulates chemotherapy resistance by inhibiting LGALS3 ubiquitin-mediated degradation via AKT/mTOR signaling activation pathway in hepatoce... by Ronghuan Fang, Zhigang Jia, Yuhang Xin, Kai Zhao, Wei Qin, Haoran Lu, Yi Zhou, Yongsheng Yang, He Fang

“…Abstract Hepatocellular carcinoma (HCC) is among the most malignant tumors and seriously threatens human health worldwide, and its incidence rate is increasing annually. …”
Get full text

Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

“…SC was similarly beneficial for patients across nodal status groups and appeared especially beneficial for patients with resectable squamous-cell tumors. Conclusion: Stage IIIA NSCLC treatment is highly variable. …”
Get full text

Machine Learning and Intelligent Diagnostics in Dental and Orofacial Pain Management: A Systematic Review by Taseef Hasan Farook, Nafij Bin Jamayet, Johari Yap Abdullah, Mohammad Khursheed Alam

“…The study explored the clinical influence, effectiveness, limitations, and human comparison outcomes of machine learning in diagnosing (1) dental diseases, (2) periodontal diseases, (3) trauma and neuralgias, (4) cysts and tumors, (5) glandular disorders, and (6) bone and temporomandibular joint as possible causes of dental and orofacial pain. …”
Get full text

18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns by Sanjay Chandrasekaran, Andrew Hollander, Xiangsheng Xu, Joseph L. Benci, James J. Davis, Jay F. Dorsey, Gary Kao

“…We confirmed that 18F-FLT-PET uptake is limited in healthy mice but enhanced in the intracranial tumors. Our data further demonstrate that 18F-FLT-PET imaging usefully reflects the inhibition of tumor by RT and correlates with changes in biomarker expression. …”
Get full text

IL-17 Affects the Progression, Metastasis, and Recurrence of Laryngeal Cancer via the Inhibition of Apoptosis through Activation of the PI3K/AKT/FAS/FASL Pathways by Yang Song, Ming Yang, Hongjian Zhang, Yan Sun, Ye Tao, Huihui Li, Jing Zhang, Yuncheng Li, Jianming Yang

“…Interleukin-17 (IL-17) from a distinct subset of CD4+ T cells may significantly induce cancer-elicited inflammation to prevent tumor immune surveillance. Methods. The expression levels of IL-17 were examined among 60 patients with LC. …”
Get full text

Targeting Interleukin-4 Receptor Alpha by Hybrid Peptide for Novel Biliary Tract Cancer Therapy by Kahori Seto, Junichi Shoda, Tomohisa Horibe, Eiji Warabi, Masayuki Kohno, Toru Yanagawa, Hiroki Bukawa, Yasuni Nakanuma, Koji Kawakami

“…In addition, intravenous administration of IL-4Rα-lytic hybrid peptide significantly inhibited tumor growth in a xenograft model of human BTC in vivo. …”
Get full text

Mucin-producing urothelial-type adenocarcinoma of the prostate with a gene mutation characteristic of intestinal adenocarcinoma: case report and literature review by Ao Yu, Ao Yu, Hongbo Su, Peiling Yu, Siqi Cai, Shuaixian Mu, Jinhui Yu, Qianting Lu, Yuan Miao, Ailin Li

“…After ruling out gastrointestinal and bladder tumors, MPUAP was confirmed. Ablation therapy was performed for the lung metastasis, followed by radical prostate chemoradiotherapy. …”
Get full text

Influence of SARS-CoV2 Pandemic on Colorectal Cancer Diagnosis, Presentation, and Surgical Management in a Tertiary Center: A Retrospective Study by Roman Taulean, Roxana Zaharie, Dan Valean, Lia Usatiuc, Mohammad Dib, Emil Moiș, Calin Popa, Andra Ciocan, Alin Fetti, Nadim Al-Hajjar, Florin Zaharie

“…There were no significant differences regarding the tumor location, postoperative 30-day mortality, or hospitalization duration. …”
Get full text

A Randomized, Double-Blind, Placebo-Controlled Trial Protocol Using the Fuzhengxiaoliu Patch for the Management of Primary Liver Cancer Pain by Li S, Wang B, Deng J, Li H, Wu Y, Fang Y, Yan B, Chen Y

“…The secondary objectives include response evaluation criteria in solid tumors (RECIST), tumor markers, TCM syndrome scores, weight, functional assessment of cancer therapy-hepatobiliary (FACT-Hep) questionnaire scores, and self-rating anxiety scale scores. …”
Get full text

Indications, contributing factors, and short-term outcomes of pneumonectomy: an 8-year retrospective study in a resource-limited setting by Mekonnen Feyissa Senbu, Dereje Gulilat, Hiwot Tadesse Habtamu

“…The primary indication for pneumonectomy was inflammatory conditions, accounting for 62.5% (70 patients), followed by carcinoid tumors at 32.1% (36 patients). Lung cancer was the diagnosis in 5.4% (6 patients) of cases. …”
Get full text

Evolution of drug therapy in patients with resectable gastric and esophageal‑gastric junction cancer by M. V. Sedova, M. A. Batov, V. S. Tretyak, A. A. Kolomeytseva, V. M. Khomyakov, N. N. Volchenko, A. A. Fedenko, A. D. Kaprin

“…Gastric cancer (GC) is the fifth most common malignant neoplasm in the world among all malignant tumors. Currently, the “gold” standard of treatment for patients with non‑metastatic cancer of the stomach and esophageal–gastric junction is surgical treatment, which is complemented by perioperative chemotherapy according to the FLOT scheme, which includes four courses of therapy before surgery and four after. …”
Get full text