The effect of ileostomy closure timing on low anterior resection syndrome in patient who underwent low anterior resection for rectal cancer by Hemn Hussain Kaka Ali, Qalandar Hussein Abdulkarim, Karzan Seerwan, Barham M. M .Salih, Omar H Ghalib Hawramy, Dara Ahmed Mohammed, Syamand Orhaman Ahmed

“…Majority of patients were overweight (21, 42%). The distance of tumors from the anal verge were less than 10 cm in (31,62%). …”
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Mendelian randomization analysis of the causal relationship between trimethylamine N-oxide and its precursors and Parkinson’s disease by Bei Zhang, Ruijie Zhang, Huiming Ren, Qiongfeng Guan, Weinv Fan, Liyuan Han

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CLINICAL EXAMPLE OF THE USE OF LIPOFILLING WITH DELAYED RECONSTRUCTION by A. D. Zikiryakhodzhayev, A. A. Masri, A. S. Sukhotko, F. N. Usov, M. V. Starkova, V. V. Ratushnaya, N. V. Evtyagina

“…Malignant breast tumors are one of the causes of disability due to lack of breast or having operational defects. …”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Abstract Gastric cancer (GC) is one of the most common malignant tumors worldwide, and its treatment has been a focus of medical research. …”
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KaRhab: an international online registry for cardiac rhabdomyomas by Vera-Maria Herrmann, Maria Arelin, Caroline G. Bergner, Julia Herrmann, Paula Janz, Henriette Kiep, Annika Mueller, Steffen Syrbe, Robert Wagner, Bardo Wannenmacher, Nadine Wolf, Michael Weidenbach, Vincent Strehlow

“…Abstract Background Cardiac rhabdomyoma (RHM) is considered one of the most frequent benign heart tumors in children. However, encounters with cardiac RHM in clinical practice remain rare. …”
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Immunohistochemical Profile of p62/SQSTM1/Sequestosome-1 in Human Low- and High-Grade Intracranial Meningiomas by Antonio Ieni, Cristina Pizzimenti, Vincenzo Fiorentino, Mariausilia Franchina, Antonino Germanò, Giovanni Raffa, Maurizio Martini, Guido Fadda, Giovanni Tuccari

“…Although, recently, p62 expression has been analyzed in different neurodegenerative and glial neoplastic diseases, no available information have been reported in meningiomas, which have an high epidemiological relevance being the second most common category of intracranial tumors after gliomas. Generally meningiomas have a benign behavior, but their recurrence is not uncommon mainly when atypical or anaplastic varieties occur. …”
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CircWDR78 inhibits the development of colorectal cancer by regulating the miR-653-3p/RGS4 axis by Chu Hao, Yunju Pu, Jiunian Li, Zhi Zhong, Zhaohui Huang, Xue Wang

“…These noncoding RNA molecules, characterized by their unique closed loop structure, displayed close associations with the progression of tumors. Methods Actinomycin D experiment and RNA digestion experiment were used to verify the circular structure characteristics of circWDR78. …”
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Mandible reconstruction after head and neck management for oral cancer: A case report and literature review by Sylvio Luiz Costa De-Moraes, Raissa Dias Fares, Alexandre Maurity de Paula Afonso, Roberto Gomes dos Santos, Ricardo Pereira Mattos

“…The use of mandibular osteotomies to allow access to tumors of the oral cavity and oropharynx is common for head and neck surgeons. …”
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Magnetic hybrid Pd/Fe-oxide nanoparticles meet the demands for ablative thermo-brachytherapy by Rogier van Oossanen, Alexandra Maier, Jérémy Godart, Jean-Philippe Pignol, Antonia G. Denkova, Gerard C. van Rhoon, Kristina Djanashvili

“…The heating ability of the best performing Pd/Fe-oxide-21 was calculated to be sufficient to ablate tumors with a radius ±4 and 12 mm using 10 and 1 mg/mL nanoparticle concentration, respectively.Conclusions Nanoparticles consisting of non-magnetic palladium-core and magnetic iron oxide shell are suitable for magnetic hyperthermia/thermal ablation under clinically safe conditions of 346 kHz and 19.1 mT, with minimal eddy current effects in combination with maximum SLP.…”
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Characterizing tertiary lymphoid structures associated single-cell atlas in breast cancer patients by Xiaokai Fan, Daqin Feng, Donggui Wei, Anqi Li, Fangyi Wei, Shufang Deng, Muling Shen, Congzhi Qin, Yongjia Yu, Lun Liang

“…Inducing TLS neogenesis can enhance the immunogenicity of tumors and improve the efficacy of immunotherapy. …”
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An Explainable Artificial Intelligence Model for the Classification of Breast Cancer by Tarek Khater, Abir Hussain, Riyad Bendardaf, Iman M. Talaat, Hissam Tawfik, Sam Ansari, Soliman Mahmoud

“…This could improve the understanding of the diagnosis and treatment of breast cancer by identifying the most important features of breast cancer tumors and the way they affect the classification task. …”
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Cost-effectiveness analysis of gumarontinib versus savolitinib for the treatment of advanced or metastatic NSCLC with MET exon 14 skipping mutations in China using partitioned surv... by Gang Fang, Zhipeng Pi, Yiping An, Xinxin Cao, Wei Li, Wei Li, Xiangjun Zhu, Jinxi Ding, Jinxi Ding

“…Background and objectivesBoth gumarontinib and savolitinib have demonstrated efficacy in treating non-small-cell lung cancer (NSCLC) with tumors harboring mesenchymal–epithelial transition factor gene exon 14 (METex14) skipping. …”
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Computer Based Correlation of the Texture of P63 Expressed Nuclei with Histological Tumour Grade, in Laryngeal Carcinomas by Konstantinos Ninos, Spiros Kostopoulos, Ioannis Kalatzis, Panagiota Ravazoula, George Sakelaropoulos, George Panayiotakis, George Economou, Dionisis Cavouras

“…Considering that P63 is mainly nuclear stain, a possible correlation between the texture of P63-stained nuclei and the tumor’s grade could be of value to diagnosis, since this may be related to biologic information imprinted as texture on P63 expressed nuclei. …”
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Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back by Hesham Abdelbary, Christopher W. Brown, Joel Werier, John Bell

“…Our hypothesis is that systemic delivery of VSVΔM51 can demonstrate tumor-specific killing of resistant EWS cells, as well as a significant decrease of tumor burden in EWS bearing mice. …”
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Pulmonary Nuclear protein in Testis (NUT) carcinoma: clinical, molecular characteristics, and treatment strategies by Jingjing Qu, Zhen Chen, Yanping Zhu, JinYan Huang, Qian Shen

“…Surgical resection with adjuvant therapy offers better outcomes for early-stage patients, while chemotherapy and immunotherapy show limited efficacy in metastatic cases due to the tumor’s aggressive behavior. Early detection and innovative therapies are essential for improving outcomes.…”
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Pan-cancer analysis of CLDN1 and its functional study in gastric cancer by Zhu Weijing, Zhang Jiaxing, Wei Yucai, Yang Shengrui, Wang Wenxuan, Li Yumin

“…Results CLDN1 was significantly upregulated in 13 types of tumors and downregulated in 7, with a strong correlation to tumor stage and grade. …”
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NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula by Yingbin Luo, Jianchun Wu, Xiaowen Zhu, Chenyuan Gong, Chao Yao, Zhongya Ni, Lixin Wang, Lulu Ni, Yan Li, Shiguo Zhu

“…Here, we found that YPF significantly inhibited the growth of Lewis lung cancer, prolonged the survival of tumor-bearing mice, promoted NK cell tumor infiltration, increased the population of NK cells in spleen, and enhanced NK cell-mediated killing activity. …”
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Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis by Qiong Zhang, Jia Duan, Yuanmei Zhang, Lei Yang, Duo Li

“…Neoadjuvant chemotherapy may shrink tumors and improve surgical outcomes, while adjuvant chemotherapy targets residual disease post-surgery. …”
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HPV16E6-Dependent c-Fos Expression Contributes to AP-1 Complex Formation in SiHa Cells by Feixin Liang, Shinichiro Kina, Hiroyuki Takemoto, Akira Matayoshi, Thongsavanh Phonaphonh, Nao Sunagawa, Keiichi Arakaki, Akira Arasaki, Hai Kuang, Hajime Sunakawa

“…To date, the major role of HPV16E6 in cancer has been considered to be its ability to inhibit the p53 tumor-suppressor protein, thereby thwarting p53-mediated cytotoxic responses to cellular stress signals. …”
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Intravenous Contrast Agent in Abdominal CT: Is It Really Needed to Identify the Cause of Bowel Obstruction? Proof of Concept by Federica Vernuccio, Dario Picone, Gregorio Scerrino, Massimo Midiri, Giuseppe Lo Re, Roberto Lagalla, Giuseppe Salvaggio

“…Adhesions were identified on unenhanced CT as the etiology of small bowel obstruction in 80% (4/5) of patients. Tumors were identified on unenhanced CT as the etiology of large bowel obstruction in 67% (4/6) of patients. …”
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