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  1. 4921

    Research progress of Traditional Chinese Medicine nursing for patients with diabetes (糖尿病中医护理研究进展) by ZHENG Xiaoyan (郑晓艳), LI Jiayue (李佳玥), ZHANG Ying (张莹), GUO Peng (郭鹏)

    Published 2023-12-01
    “…Diabetes has become a member of the epidemic that seriously threatens human health through concentric cerebrovascular disease, tumors, etc. With the great achievements in the clinical practice of Traditional Chinese Medicine nursing in China, Traditional Chinese Medicine nursing intervention for diabetes is based on the basic theory and practical guidance of Traditional Chinese Medicine, exploring the research of appropriate techniques of Traditional Chinese Medicine nursing to prevent and treat diabetes, and providing better help for the treatment of complications of diabetes patients. …”
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  2. 4922

    The Nrf-2/HO-1 Signaling Axis: A Ray of Hope in Cardiovascular Diseases by Xueyan Zhang, Yihan Yu, Hanyu Lei, Yufeng Cai, Jie Shen, Ping Zhu, Qingnan He, Mingyi Zhao

    Published 2020-01-01
    “…Rheumatic heart disease, cardiac tumors, arteriosclerosis, arrhythmia, hypertensive heart disease, and myocardial infarction have also been treated during experiments. …”
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  3. 4923

    Sperm Cryopreservation before Testicular Cancer Treatment and Its Subsequent Utilization for the Treatment of Infertility by Jana Žáková, Eva Lousová, Pavel Ventruba, Igor Crha, Hana Pochopová, Jaroslava Vinklárková, Eva Tesařová, Mohamed Nussir

    Published 2014-01-01
    “…Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. …”
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  4. 4924

    Novel Chlorin with a HYNIC: Synthesis, <sup>99m</sup>Tc-Radiolabeling, and Initial Preclinical Evaluation by Alexander Popov, Nikita Suvorov, Mariia Larkina, Evgenii Plotnikov, Ruslan Varvashenya, Vitalina Bodenko, Gleb Yanovich, Petr Ostroverkhov, Maxim Usachev, Elena Filonenko, Mikhail Belousov, Mikhail Grin

    Published 2024-12-01
    “…One of the most effective <sup>99m</sup>Tc chelators is 6-hydrazinylnicotinic acid (HYNIC), which, when combined with various vector molecules, can be used for targeted delivery of radionuclides to tumor tissues. At the same time, it is known that tetrapyrrole macrocycles are capable of selective accumulation in tumors, and thus can be used to target radiopharmaceuticals with <sup>99m</sup>Tc. …”
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  5. 4925

    Role of tertiary lymphoid structures and B cells in clinical immunotherapy of gastric cancer by Weiyi Chen, Lingli Zhang, Man Gao, Ning Zhang, Rumeng Wang, Yang Liu, Yan Niu, Lizhou Jia, Lizhou Jia

    Published 2025-01-01
    “…Gastric cancer is a common malignant tumor of the digestive tract, and its treatment remains a significant challenge. …”
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  6. 4926

    Augmented immunogenicity of the HPV16 DNA vaccine via dual adjuvant approach: integration of CpG ODN into plasmid backbone and co-administration with IL-28B gene adjuvant by Yan Zhou, Ting Zhang, Zhirong Wang, Xuemei Xu

    Published 2025-01-01
    “…Furthermore, vaccination with CpG-modified mE7/HSP70 and mE6/HSP70 plasmids, alongside the Interleukin-28B (IL-28B) gene adjuvant, generated substantial preventive and therapeutic antitumor effects against HPV E6- and E7-expressing tumors in C57BL/6 mice. These results suggested that integrating these multiple strategies into an HPV DNA vaccine holds promise for effectively controlling HPV infection and related diseases.…”
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  7. 4927

    Prognosis of invasive encapsulated follicular variant and classical papillary thyroid carcinoma: a propensity score-matched study using the SEER database by Shuai Jin, Lang Xie, Gongyou Zhang, Lei Liu, Kaide Xia, Hongzhou Liu, Haiwang Zhang, Peng Li

    Published 2025-01-01
    “…Abstract The latest World Health Organization Classification of Tumors, Fifth Edition, recognizes the invasive encapsulated follicular variant of papillary thyroid carcinoma (IEFVPTC) as a distinct malignant entity rather than a subtype of papillary thyroid carcinoma (PTC). …”
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  8. 4928

    Bioadhesive Chitosan Films Loading Curcumin for Safe and Effective Skin Cancer Topical Treatment by Seila Tolentino, Mylene M. Monteiro, Felipe Saldanha-Araújo, Marcilio Cunha-Filho, Tais Gratieri, Eliete N. Silva Guerra, Guilherme M. Gelfuso

    Published 2024-12-01
    “…<b>Conclusion</b>: The developed chitosan-based bioadhesive films represent a promising alternative for the topical treatment of skin tumors using curcumin.…”
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  9. 4929

    Novel submucosal injection material comprising fully synthetic and self-assembling peptide solution in endoscopic submucosal dissection: A pilot study by Kengo Kasuga, Keigo Sato, Ko Nakata, Hirohito Tanaka, Hiroko Hosaka, Shiko Kuribayashi, Yoji Takeuchi, Toshio Uraoka

    Published 2025-01-01
    “…This study evaluated the safety and feasibility of a new injection solution (PuraLift) in ESD for early-stage gastrointestinal tumors. This prospective, single-arm, single-center pilot study included 11 patients with gastrointestinal neoplasms of the stomach (n = 5) or colorectum (n = 6) who underwent ESD. …”
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  10. 4930

    Snail Expression is Positively Correlated with Depth of Invasion in Colorectal Carcinoma by Upik Anderiani Miskad, Fardah Akil, Muhammad Husni Cangara, Haslindah Dahlan, Gina Andyka Hutasoit, Muhammad Riza Ilyasa

    Published 2024-12-01
    “…BACKGROUND: Colorectal carcinoma ranks as the second deadliest and third most prevalent cancer globally. The depth of tumor invasion and the presence of tumor-infiltrating lymphocytes (TILs) are linked to survival rates in this disease. …”
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  11. 4931

    NTRK amplification occurs frequently in pan-TRK immunopositive dedifferentiated liposarcomas by Zoltán Lippai, Gergő Papp, Károly Szuhai, Johanna Sápi, Katalin Dezső, Zoltán Sápi

    Published 2025-01-01
    “…Pan-TRK antibody, which shows the overexpression of the NTRK1-2-3 genes, is a useful tool to detect tumors with or without NTRK gene alterations, due to high negative predictive value. …”
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  12. 4932

    Urinary Exosomal Long Noncoding RNA TERC as a Noninvasive Diagnostic and Prognostic Biomarker for Bladder Urothelial Carcinoma by Chen Chen, Anquan Shang, Zujun Sun, Yuting Gao, Jingjuan Huang, Yili Ping, Wenjing Chang, Chenzheng Gu, Junjun Sun, Ping Ji, Yi Yuan, Renquan Lu, Dong Li

    Published 2022-01-01
    “…Furthermore, this noninvasive assay could distinguish low-grade and high-grade tumors (P=0.0153). Conclusions. TERC is enriched in urinary exosomes from BLCA patients. …”
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  13. 4933

    Upregulated Expression of Indoleamine 2, 3-Dioxygenase in Primary Breast Cancer Correlates with Increase of Infiltrated Regulatory T Cells In Situ and Lymph Node Metastasis by Jinpu Yu, Jingyan Sun, Shizhen Emily Wang, Hui Li, Shui Cao, Yizi Cong, Juntian Liu, Xiubao Ren

    Published 2011-01-01
    “…The IDO expression was significantly upregulated in tumors of more advanced stages and with more extensive lymph node metastasis, and displayed positive linear correlation with the density of Foxp3+ Tregs. …”
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  14. 4934

    Utility and clinical significance of endoscopic ultrasound-guided tissue acquisition for diagnosing lymphadenopathies in biliary tract cancer by Katsuhiko Sato, Minoru Shigekawa, Syuhei Yamamoto, Takayuki Matsumae, Yu Sato, Teppei Yoshioka, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara

    Published 2025-01-01
    “…In 35 patients with difficulty in obtaining pathological proof from primary tumors, obtaining a pathological diagnosis was successful in 24 patients. …”
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  15. 4935
  16. 4936

    Successful thoracoscopic-assisted resection of a functional paraganglioma in the mediastinum with extracorporeal circulation: a case report by Zhihui Yang, Xiaojie Huang, Danting Zhou, Tao Tang, Hengxing Liang, Wenliang Liu, Fenglei Yu, Chen Chen

    Published 2025-01-01
    “…The surgery was successfully completed, and follow-up assessments showed no signs of tumor recurrence or metastasis. Conclusions Functional mediastinal paraganglioma is a rare neuroendocrine tumor, with complete surgical resection being the gold standard treatment. …”
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  17. 4937

    Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues by Ioannis Alexandros Charitos, Andrea Ballini, Stefania Cantore, Mariarosaria Boccellino, Marina Di Domenico, Elisa Borsani, Riccardo Nocini, Michele Di Cosola, Luigi Santacroce, Lucrezia Bottalico

    Published 2021-01-01
    “…These problems are related not only to the growth of tumors in animal models and their rejection in transplant cases but also to ethical and social issues about the use of embryonic cells. …”
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  18. 4938

    MAC30 Knockdown Inhibits Proliferation and Enhance Apoptosis of Gastric Cancer by Suppressing Wnt/β-Cateninsignaling Pathway by Xiaohong Wu, Yong Zhang, Junping Guo, Xun Yan, Li Shen, Jianping Zhou, Jun Zhao, Min Zhuang, Zhihong Cao

    Published 2020-01-01
    “…Upregulation of meningioma-associated protein (MAC30) has been found in many solid tumors and can regulate the proliferation, differentiation, and apoptosis of different tumor cells. …”
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  19. 4939

    Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies by Thaiene Avila Reis, Ana Elise Jaculi, Rubens da Costa Alves, Tais Gratieri, Ricardo Bentes Azevedo, Graziella Anselmo Joanitti, Guilherme Martins Gelfuso, Marcilio Cunha-Filho

    Published 2018-01-01
    “…Considering the feasibility of the aluminum phthalocyanine chloride (AlPcCl) application in the topical photodynamic therapy of cutaneous tumors and the lack of HPLC methods capable of supporting skin permeation experiments using this compound, the aim of this study was to obtain a simple and selective chromatographic method for AlPcCl determination in skin matrices. …”
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  20. 4940

    The prognostic and immunomodulatory role of the MMR system in patients with stomach adenocarcinoma by Zhihui Tian, Lili Yang, Rong Yang, Wenhui Yang

    Published 2025-01-01
    “…The clinical value of the MMR molecular marker as an immunotherapy for advanced solid tumors has been documented. However, this therapy is not effective in some patients. …”
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