Antitumor Activity of Intratumoral Ethanol Injection in an Orthotopic Pancreatic Cancer Cell Mouse Xenograft Model by Wen-Ying Zhang, Zhen-Dong Jin, Feng Liu, Hai-Hua Yuan, Bin Jiang

“…Tumor volume, relative tumor volume (RTV), and histopathology were evaluated. …”
Get full text

Enhancing signal-to-noise ratio in real-time LED-based photoacoustic imaging: A comparative study of CNN-based deep learning architectures by Avijit Paul, Srivalleesha Mallidi

“…Through experimentation with in vitro phantoms, ex vivo mouse organs, and in vivo tumors, we compare basic convolutional autoencoder and U-Net architectures, explore hierarchical depth variations within U-Net, and evaluate advanced variants of U-Net. …”
Get full text

Occult metastases and survival of lung cancer by clinical diagnosis and CT screening: A simulation study. by Xing Chen, Ghulam Muhammad Kanhar, Songli Hu, Chaomin Wu, Guanqun Chao, Mengqi Jing, Fengjiang Zhang, Millennia Young, Marek Kimmel, Liying Chen, Olga Y Gorlova

“…Among clinically detected Stage I lung cancers with tumor diameter 1-2 cm, 78% were true stage N0M0 (no occult metastases) while it was only 37% for patients with tumor diameters of 2-3 cm. …”
Get full text

Comparative evaluation of calretinin immunohistochemical expression in calcifying odontogenic cyst and ameloblastoma by Maryam Mahdizadeh, Nazanin Mahdavi, Ali Bijani, Fatima Bijani

“…Abstract Background Calretinin is a 29 kilodalton (KDa) calcium-binding protein that is expressed in normal and tumoral tissues. The expression of calretinin has been shown in the dental epithelium during odontogenesis and in different odontogenic cysts and tumors such as ameloblastoma. …”
Get full text

Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway by Jiale Tian, Weiwei Wang, Jichao Zhu, Yun Zhuang, Chunrun Qi, Zhengxin Cai, Wenhui Yan, Wenying Lu, Anquan Shang

“…Tumors may develop a variety of immune evasion mechanisms during the progression of colorectal cancer (CRC). …”
Get full text

Plexiform Schwannoma of the Penis: A Rare Subtype of Genital Schwannoma by Chrysovalantis Gkekas, Vasileios Kalyvas, Evangelos N. Symeonidis, Apostolos Malioris, Michail Papathanasiou, Nikolaos Kalinderis, Kyriakos Moisidis, Konstantinos Hatzimouratidis

“…Schwannomas are benign, encapsulated neurogenic tumors which present in diverse histological subtypes despite the limited variety of their cellular constituents. …”
Get full text

PHOTODYNAMIC THERAPY OF CONDYLOMATA ACUMINATE by V. N. Galkin, A. V. Molochkov, V. A. Molochkov, S. V. Korenev, T. E. Sukhova, Zh. S. Kuntcevich, Yu. S. Romanko

“…In 10% of people with the human papilloma virus develops condylomata acuminate, which can be transformed into malignant tumors. The most common treatment of condylomata acuminate is a conservative treatment, namely, the local chemical or physical destruction of the lesions and immunotherapy. …”
Get full text

Potential and development of cellular vesicle vaccines in cancer immunotherapy by Wenxi Zhao, Xianjun Li, Jialu Guan, Shuai Yan, Lizhi Teng, Xitong Sun, Yuhan Dong, Hongyue Wang, Weiyang Tao

“…Abstract Cancer vaccines are promising as an effective means of stimulating the immune system to clear tumors as well as to establish immune surveillance. …”
Get full text

AEBP1 Promotes Glioblastoma Progression and Activates the Classical NF-κB Pathway by Kai Guo, Lei Song, Jianyong Chang, Peicheng Cao, Qi Liu

“…The expression of AEBP1 in GBM was assessed by bioinformatics analysis and qRT-PCR; the effects of AEBP1 on GBM cell proliferation, migration, invasion, and tumor growth in vitro and in vivo were detected by a CCK-8 assay, colony formation assay, scratch assay, Transwell assay, and subcutaneous tumor formation, respectively. …”
Get full text

Giant Bilateral Adrenal Myelolipoma with Congenital Adrenal Hyperplasia by S. Al-Bahri, A. Tariq, B. Lowentritt, D. V. Nasrallah

“…Massive growth of these tumors, as in our case, can produce compression and hemorrhagic symptoms. …”
Get full text

Synthesis and Experimental Validation of New Designed Heterocyclic Compounds with Antiproliferative Activity versus Breast Cancer Cell Lines MCF-7 and MDA-MB-231 by Vincenza Barresi, Carmela Bonaccorso, Domenico A. Cristaldi, Maria N. Modica, Nicolò Musso, Valeria Pittalà, Loredana Salerno, Cosimo G. Fortuna

“…With this aim, we recently designed and synthesized novel compounds with high efficacy and specificity for the treatment of breast tumors. Based on the obtained results, we constructed a Volsurf+ (VS+) model using a dataset of 59 compounds able to predict the in vitro antitumor activity against MCF-7 cancer cell line for new derivatives. …”
Get full text

From Images to Genes: Radiogenomics Based on Artificial Intelligence to Achieve Non‐Invasive Precision Medicine in Cancer Patients by Yusheng Guo, Tianxiang Li, Bingxin Gong, Yan Hu, Sichen Wang, Lian Yang, Chuansheng Zheng

“…In this review, the history of radiogenomics is enumerated, related omics technologies, the five basic workflows and their applications across tumors, the role of AI in radiogenomics, the opportunities and challenges from tumor heterogeneity, and the applications of radiogenomics in tumor immune microenvironment. …”
Get full text

Asymptotic analysis of mathematical model describing a new treatment of breast cancer using AZD9496 and palbociclib by Ophir Nave, Ophir Nave

“…Breast cancer is a malignant tumor that originates in the breast tissue. It is the most common malignant tumor in women. …”
Get full text

Endogenous Cushing’s Syndrome with Precocious Puberty in an 8-Year-Old Boy due to a Large Unilateral Adrenal Adenoma by Muhammad Rajib Hossain, Md. Mashiul Alam, Junaid Nabi, Mahzabin Kibria

“…Adrenocortical tumors (ACTs) causing Cushing’s syndrome are extremely rare in children and adolescents. …”
Get full text

Fluorescence Diagnostics of Colon Malignant and Premalignant Lesions Using 5-Aminolevulinic Acid by Elena V. Filonenko, Andrey D. Kaprin, Antonina A. Raszhivina, Antonina N. Urlova, Andrey M. Nechipai

“…The application of the method during colonoscopy allows specifying diagnosis, identifying areas of colon tumors transformation, and also showing a place for targeted biopsy. …”
Get full text

Dual Roles of IL-27 in Cancer Biology and Immunotherapy by Marina Fabbi, Grazia Carbotti, Silvano Ferrini

“…Several pieces of evidence, obtained in preclinical tumor models, indicated that IL-27 has a potent antitumor activity, related not only to the induction of tumor-specific Th1 and cytotoxic T lymphocyte (CTL) responses but also to direct inhibitory effects on tumor cell proliferation, survival, invasiveness, and angiogenic potential. …”
Get full text

A sterilization method for human decellularized vaginal matrices by Jayson Sueters, Leonie de Boer, Freek Groenman, Judith A. F. Huirne, Theo H. Smit, Sebastian A. J. Zaat

“…Abstract Vaginal reconstruction is necessary for various congenital and acquired conditions, including vaginal aplasia, trauma, tumors, and gender incongruency. Current surgical and non-surgical treatments often result in significant complications. …”
Get full text

Impact of Surgeon Experience in the Resection of Basal Cell Carcinoma of the Head and Neck Region by Carlos Gonzalo Acosta Mayorga, Piedad Elizabeth Acurio Padilla, Guido Nino Guida Acevedo

“…Tumor size was up to 20 mm in 354 cases. Positive surgical margins were observed in 92 cases. …”
Get full text

Epithelial-Mesenchymal Transition Phenotype, Metformin, and Survival for Colorectal Cancer Patients with Diabetes Mellitus II by Yaodu Wang, Zhiyang Wu, Likuan Hu

“…Expression of E-cadherin and vimentin in tumors was detected by immunohistochemistry (IHC), and statistical analysis was performed using SPSS 19.0. …”
Get full text

Laparoscopic Resection of a Left Upper Quadrant Mass Leading to a Surprise Diagnosis by Hugo J. R. Bonatti, Reinhardt O. Sahmel, Rodrigo B. Erlich

“…The gastric fundus showed multiple nodules, and therefore, a modified sleeve gastrectomy was done; also, a 2 cm nodule in segment 5 of the liver and an omental nodule were removed. The tumors and gastrectomy specimen were placed in an endobag and removed through a periumbilical mini-incision. …”
Get full text