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4661
Cancer Vaccine by Fusions of Dendritic and Cancer Cells
Published 2009-01-01“…DCs/tumor fusion vaccine stimulates potent antitumor immunity in the animal tumor models. …”
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4662
A Rapid Biochemical and Radiological Response to the Concomitant Therapy with Temozolomide and Radiotherapy in an Aggressive ACTH Pituitary Adenoma
Published 2017-01-01“…After two months of concurrent temozolomide and radiotherapy, cortisol normalization and significant tumor shrinkage were observed. After 22 months of follow-up, there is still no evidence of tumor recurrence. …”
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4663
Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics
Published 2015-03-01“…We found that the model closely matches previously published data, and while viral oncolysis is fundamental in reducing tumor burden, increased stimulation of cytotoxic T cells leads to a short-term reduction in tumor size, but a faster relapse. …”
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4664
Diplopia, Convergent Strabismus, and Eye Abduction Palsy in a 12-Year-Old Boy with Autoimmune Thyroiditis
Published 2016-01-01“…Pseudotumor cerebri (PTC) is defined by clinical criteria of increased intracranial pressure, elevated intracranial pressure with normal cerebrospinal fluid (CSF) composition, and exclusion of other causes such tumors, vascular abnormalities, or infections. The association of PTC with levothyroxine (LT4) has been reported. …”
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4665
Arthroscopic Management of Juxta‐Articular Proximal Tibial Chondroblastoma: A Case Report and Literature Review
Published 2025-01-01“…ABSTRACT Background Chondroblastoma is a rare bone tumor that originates from the epiphysis, constitutes around 1% of all primary bone tumors and is recognized for its tendency to exhibit local invasiveness, as well as the possibility of metastasis and recurrence in nearby areas. …”
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4666
Immunotherapy of Brain Cancers: The Past, the Present, and Future Directions
Published 2010-01-01“…Immunotherapy's strength is that it efficiently treats relatively small tumors in experimental animal models. For some patients, immunotherapy has worked for them while not showing long-term toxicity. …”
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4667
Pathological Characteristics, Prognostic Determinants and the Outcome of Patients Diagnosed with Colorectal Adenocarcinoma at the University Teaching Hospital of Kigali
Published 2022-01-01“…Mean age of the participants was 54.26 years, the main symptom was rectal bleeding (46.5%), rectal adenocarcinoma NOS represented 40.6%, conventional adenocarcinoma was 60.4%, most tumors were of Grade II (54.5%), most common stage was pT3N0 (20.8%), resection margins were free at 71.3%, lympho-vascular invasion was 49.5% of cases, a high immune response was in 71.3% of cases and of 101cases, and 55.4% were still alive at the end of the data collection, with 29.3% of patients have overall survival of 5 years. …”
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4668
FOTELP-VOX 2024: Comprehensive overview of its capabilities and applications
Published 2024-01-01“…This study presents the application of FOTELP-VOX in simulating absorbed dose distributions in various clinical scenarios, including radiotherapy treatment planning for salivary gland tumors, eye melanoma and breast cancer. The results demonstrate the program's capability to replicate complex dose distributions with high accuracy, in comparison with clinical techniques like volumetric modulated arc therapy and 3-D conformal radiotherapy. …”
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4669
Small Cell Neuroendocrine Carcinoma of the Urinary Tract Successfully Managed with Neoadjuvant Chemotherapy
Published 2013-01-01“…Following a diagnosis of small cell neuroendocrine carcinomas of the ureter and the bladder, thoracoabdominal-pelvic CT was done, and the staging of the tumor was done in the bladder (T2N0M0) and (T1N0M0) in the ureter. …”
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4670
46, XY Complete Gonadal Dysgenesis (Swyer Syndrome) Presenting as Primary Amenorrhea in a Normomorphic Adult Female From Kakamega, Kenya
Published 2025-01-01“…Management includes hormone replacement therapy and gonadectomy because of the increased risk of gonadal tumors. The patient was educated about her condition, initiated on combined contraceptive pills, and counseled on exploratory laparoscopic gonadectomy. …”
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4671
Retroperitoneal Extraovarian Fibrothecoma Mimicking a Malignant Epithelial Ovarian Carcinoma
Published 2012-01-01“…Fibrothecomas are benign sex cord-stromal tumors which rarely originate outside of the ovary. …”
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4672
Nano-technological advancements in multimodal diagnosis and treatment
Published 2024-11-01“…Unlike traditional treatments, which muddle the distinction between diseased and healthy tissue, gold nanoparticles (AuNPs) directly target tumors, using increased permeability and retention (EPR) effects for crystal-clear, early-stage detection. …”
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4673
Bioinformatics approaches to multi-omics analysis of the potential of CDKN2A as a biomarker and therapeutic target for uterine corpus endometrial carcinoma
Published 2025-01-01“…Prior research has demonstrated an association between cyclin-dependent kinase inhibitor 2 A (CDKN2A) and various tumors. As a member of the INK4 family, CDKN2A is involved in cell cycle regulation by controlling CDKs. …”
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4674
Rare Presentation of Cardiotoxicity Related to 5-Fluorouracil
Published 2020-01-01“…5-Fluorouracil (5-FU) is a chemotherapeutic agent frequently used for the treatment of solid tumors. In a few cases, 5-FU can be associated with coronary vasospasm, cardiac ischemia, or life-threatening arrhythmias. …”
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4675
Expression of Cyclin D1 in Oral Squamous Cell Carcinoma
Published 2021-12-01“…In this study, we aimed to study the expression of cyclin D1 in oral squamous cell carcinoma (OSCC) and find its association with the different grades of oral tumors, if any. Methods: This cross-sectional study included 40 formalin-fixed paraffin-embedded tissue blocks specimens of OSCC with variable grades. …”
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4676
Delayed Cerebral Radiation Necrosis after Neutron Beam Radiation of a Parotid Adenocarcinoma: A Case Report and Review of the Literature
Published 2014-01-01“…Neutron beam radiation is a highly potent form of radiotherapy that may be used to treat malignant tumors of the salivary glands. This report describes a patient who underwent neutron beam radiation for a parotid adenocarcinoma and who developed biopsy-confirmed temporal lobe radiation necrosis thirty months later. …”
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4677
Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literat...
Published 2018-01-01“…The diagnosis of PIOSCC is difficult and based on exclusion of other carcinomas, including metastatic tumors from other primary sites. Here, we report an extremely rare case of initial-stage PIOSCC derived from the OKC with unusual keratoameloblastomatous change of the maxilla.…”
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4678
Age-related immunosenescence and Epstein–Barr virus-positive mucocutaneous ulcer presenting as oral cancer: a case report
Published 2025-01-01“…It represents a benign lymphoproliferative disorder that clinically may mimic malignant tumors. However, EBVMCU typically progresses slowly and often resolves spontaneously without specific treatment, emphasizing the critical need for differential diagnosis from malignancies. …”
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4679
Elucidating Clinical Queries for Tailored Therapy in Patients with Prolactinoma
Published 2024-12-01“…Unlike other pituitary tumors, the first-line management has traditionally been pharmacological rather than surgical. …”
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4680
Construction of oncolytic reporter influenza viral vectors and assessment of their safety following intracranial administration in rats
Published 2024-11-01“…INTRODUCTION: Oncolytic viruses are a promising approach for treating malignant brain tumors as part a of combination therapy. OBJECTIVE: To develop reporter influenza A viruses expressing NanoLuc luciferase and evaluate their safety following intracranial administration in rats. …”
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