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4621
A study of the histopathological spectrum of thyroid neoplasms in a tertiary health care center
Published 2024-12-01“…Background: Thyroid gland lesions are common and can result from systemic conditions such as Graves’ disease or localized abnormalities like nodular enlargement or tumors. Thyroid malignancies are the most prevalent endocrine cancers, accounting for approximately 92% of all endocrine malignancies. …”
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4622
Multifunctional Nanoparticles as Radiosensitizers to Overcome Hypoxia-Associated Resistance in Cancer Radiotherapy
Published 2024-12-01“…PFH-based oxygen carriers can augment oxygenation within tumor tissues, thereby mitigating radioresistance. …”
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4623
Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma
Published 2022-07-01“…All data were randomly allocated into a training set and a testing set to develop and validate the nomogram model.Results The findings showed that age, sex, grade, tumor size, multiple primary malignant tumors, stage, primary site surgery (PSS), radiotherapy (RT), and chemotherapy (CT) were correlated with prognosis (p < .05). …”
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4624
Global Research Landscape and Intellectual Structure of Boron Neutron Capture Therapy Research: A Review Based on Scientometric Tools
Published 2025-01-01“…Boron Neutron Capture Therapy (BNCT) is a non-invasive therapeutic technique for treating invasive malignant tumors. A tremendous amount of research is published in this area every year, and it needs to be analyzed and evaluated to measure the growth and trends of the research. …”
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4625
The Legal System of Gene Therapy Contracts
Published 2024-12-01“…This has enabled the treatment of many diseases, such as heart and vascular diseases, cancerous tumors, neurological diseases, viral hepatitis, diabetes, and congenital birth defects, among others. …”
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4626
Dihydroartemisinin inhibits EphA2/PI3K/Akt pathway-mediated malignant behaviors and vasculogenic mimicry in glioma stem cells
Published 2025-02-01“…Gliomas, the most prevalent primary brain tumors, exhibit a poor five-year survival rate despite advances in various treatments, necessitating further studies to understand tumor progression and develop new therapies, particularly targeting EphA2, which is implicated in vasculogenic mimicry and glioma progression. …”
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4627
Insight of microRNA role in Colorectal Cancer
Published 2020-05-01“…Differential miRNAs expression among tumors and non-tumor controls are highly valuable in recognizing miRNAs that could have vital role in carcinogenesis. …”
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4628
Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations
Published 2018-01-01“…Traditional treatment methods for patients with hepatocellular carcinoma have shown poor efficacy in killing residual cancer cells for a long time. In recent years, tumor immunotherapy has emerged as a promising method owing to its safety and efficacy with respect to delaying the progression of advanced tumors and protecting postoperative patients against tumor relapse and metastasis. …”
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4629
Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages
Published 2022-01-01“…HUC-MSCs were unable to form any tumor in immunodeficiency or normal mice with or without inflammatory stimulation. …”
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4630
Does Melanoma Begin in a Melanocyte Stem Cell?
Published 2012-01-01“…These techniques can be used to design experiments to help answer many questions regarding the role of MSCs or melanocyte precursors in the formation of melanoma stem cells and tumors following exposure to UVA/UVB radiation.…”
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4631
FIRST RUSSIAN EXPERIENCE OF USING THE INTEGRATED SYSTEM OF LASER THERMOABLATION THERAPY IN THE TREATMENT OF METASTATIC LIVER CANCER
Published 2017-09-01“…One of the most modern and promising ways to overcome this obstacle is the use of minimally invasive methods of tumor destruction. This article presents two observations of the clinical application of the laser ablator “Echolaser X4”: open laser ablation of the metastatic focus with subsequent atypical liver resection and percutaneous laser ablation of the metastasis of the neuroendocrine tumor into the liver. …”
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4632
Metastatic Infiltrating Ductal Carcinoma of the Breast to the Colon: A Case Report and Literature Review
Published 2013-01-01“…Colonic metastatic disease mimics primary colonic tumors in its presentation. Colonic metastatic involvement is a poor prognostic sign, and the pathologist should be informed about the history of the primary breast cancer when examining the pathologic specimens. …”
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4633
Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma
Published 2025-01-01“…In this study, we show that fibroblast growth factor 5 (FGF5) signaling is integral for many infantile MBSHH cases and that FGF5 expression is uniquely upregulated in infantile MBSHH tumors. Similarly, mice lacking SUFU (Sufu-cKO) ectopically express Fgf5 specifically along the secondary fissure where GNPs harbor preneoplastic lesions and show that FGFR signaling is also ectopically activated in this region. …”
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4634
Biomarker‐induced gold aggregates enable activatable near‐infrared‐II photoacoustic image‐guided radiosensitization
Published 2025-01-01“…Abstract Current radiotherapy (RT) lacks the ability to accurately discriminate between tumor and healthy tissues, resulting in significant radiation‐induced damage for patients. …”
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4635
Unveiling the role of SYNGR4 in breast cancer development: a novel target for immunotherapy
Published 2025-01-01“…SYNGR4 overexpression affects breast cancer proliferation, migration, and tumor immune infiltration, and promotes breast cancer tumor-associated macrophage polarization toward M2.DiscussionSYNGR4 overexpression can affect the prognosis of breast cancer patients by promoting M2 polarization of tumor-associated macrophages in breast cancer, and this molecule may be a novel target for breast cancer immunotherapy.…”
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4636
Endoscopic Resection of a Pedunculated Brunner’s Gland Hamartoma of the Duodenum
Published 2016-01-01“…This case underscores the usefulness of endoscopic ultrasonography for the diagnosis of duodenal subepithelial tumors.…”
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4637
Malignant Transformation of Temporal Bone Schneiderian Papilloma Associated with HPV-6
Published 2021-01-01“…Temporal bone Schneiderian papillomas (TBSPs) rarely present as a primary tumors arising from the middle ear and mastoid process. …”
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4638
Exosomal lncRNAs as diagnostic and therapeutic targets in multiple myeloma
Published 2025-01-01“…Existing research indicates that exosomal long non-coding RNAs (lncRNAs) play a crucial regulatory role in the initiation and progression of tumors, involving various interactions such as lncRNA-miRNA, lncRNA-mRNA, and lncRNA-RNA binding proteins (RBP). …”
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4639
A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology
Published 2025-02-01“…Numerous studies have demonstrated that Schisandrin B exhibits significant antitumor activity against various malignant tumors in preclinical studies, which is achieved by inhibiting cell proliferation and metastasis and promoting apoptosis. …”
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4640
Retrospective Analysis of the Efficacy and Safety of Ultrasound-Guided Radiofrequency Ablation in the Treatment of Papillary Thyroid Microcarcinoma: A Follow-Up Study of Continuous...
Published 2024-01-01“…The efficacy of ultrasound-guided RFA was evaluated by measuring the tumor volume reduction rate (VRR), tumor disappearance rate, and disease progression in 358 patients with low-risk unifocal PTMC who underwent ultrasound-guided RFA at Hangzhou Weja Hospital, while the safety was evaluated by measuring their complications. …”
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