Impact of Anterior Commissure Involvement and Frozen Guided Resections on Oncological Outcomes after Laser Cordectomy in Early Glottic Cancers – A 10-year Retrospective Analysis fr... by Elizabeth Mathew Iype, Ankit Vishwani, Bipin T Varghese, Shaji Thomas, Sahya S Lal

“…Conclusion: TLM is a safe and effective treatment of early glottic carcinoma. Apart from tumor (T) staging, ACI and frozen positivity were negative predictive factors. …”
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Ectopic Pancreas in the Stomach Successfully Resected by Endoscopic Submucosal Dissection by Masaya Iwamuro, Takao Tsuzuki, Shogen Ohya, Hiroyuki Okada, Takehiro Tanaka, Keisuke Hori, Masahide Kita, Seiji Kawano, Yoshiro Kawahara, Kazuhide Yamamoto

“…A 32-year-old Japanese man presented with a gastric submucosal tumor. Esophagogastroduodenoscopy showed a sessile submucosal tumor measuring approximately 10 mm in diameter on the greater curvature of the gastric antrum. …”
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Triple-drug antibiotic therapy for disseminated nocardial abscess in the mediastinum and brain of an immunocompetent patient: a case report by Yue Zhang, Zhongchun Qi, Hua Li, Hui Gao

“…After twice discussions with multidisciplinary team (MDT) to rule out the possibility of mediastinal and intracranial metastatic tumors, we promptly initiated treatment with a triple-drug antibiotic regimen consisting of imipenem/cilastatin sodium, linezolid dextrose, and Trimethoprim-sulfamethoxazole (TMP-SMX). …”
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Case Study of a Parotid Gland Adenocarcinoma Dedifferentiated from Epithelial-Myoepithelial Carcinoma by Salih Aydın, Umit Taskin, Kadir Ozdamar, Kadir Yücebas, Mehmet Sar, Mehmet Faruk Oktay, Ümit Seza Tetikkurt

“…Dedifferentiation is defined as high-grade malignant tumor development out of a low-grade malignant tumor. …”
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Temporal integration of ResNet features with LSTM for enhanced skin lesion classification by Sasmita Padhy, Sachikanta Dash, Naween Kumar, Shailendra Pratap Singh, Gyanendra Kumar, Poonam Moral

“…The approach tackles issues including class imbalance and the necessity for enhanced sensitivity in identifying malignant tumors. The ISIC2020 and HAM10000 benchmark datasets were employed for evaluation, utilizing sophisticated data augmentation methods and weighted loss functions to improve performance. …”
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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

“…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). …”
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Spastic Paraparesis in Young Men With Spinal Meningioma and Spinal Arteriovenous Malformation: A Case Report by Leonard Christianto Singjie, Ivan Jeremia, Esdras Ardi Pramudita

“…This case report presents spinal cord tumors together with arteriovenous malformation (AVM) in young men, where there are no previous case reports that the authors can find. …”
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Epithelioid Hemangioma of the Carpus Presenting as Aneurysmal Bone Cyst by Juston Fan, DO, William H. Fang, DO, MS, Evelyn Thomas, DO, Ali Nael, MD, Mark N. Halikis, MD, Amirhossein Misaghi, MD

“…Its varied presentation poses diagnostic challenges because of its ability to mimic other tumors. An 18-year-old boy presented with a painful dorsal mass on the right wrist, exhibiting features on preoperative imaging consistent with an expansile, radiolucent lesion. …”
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Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature by David G. Deckey, Andrea Fernandez, Nina J. Lara, Steve Taylor, Jamal McClendon, David M. Bennett

“…Complete resection of the tumor, including a three-level neurotomy, was achieved by posterior decompression/laminectomy. …”
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Procalcitonin and C-reactive protein - early predictors of low colorectal anastomotic leakage by Yu. A. Shelygin, M. A. Tarasov, M. A. Sukhina, I. V. Zarodnyuk, Ye. G. Rybakov

“…Overall 100 patients underwent surgery for epithelial tumors of rectum in the period 2013-2016 yy in the volume of LAR with the formation of anastomosis and preventive stoma. …”
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Optogenetic screening of MCT1 activity implicates a cluster of non-steroidal anti-inflammatory drugs (NSAIDs) as inhibitors of lactate transport. by Scott A Wegner, Hahn Kim, José L Avalos

“…This limitation partly arises from the existence of both isoforms in certain tumors, however existing high-affinity MCT1/4 inhibitors are years away from human testing. …”
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MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis by Vishesh Khanna, Gohar Eslami, Rochelle Reyes, Robert Diep, Sebastian Fernandez-Pol, Henning Stehr, Carlos Jose Suarez, Harlan Pinto, James M. Ford, Tian Yi Zhang, Christopher T. Chen

“…Abstract Murine double minute 2 (MDM2) inhibitors have shown promising activity in TP53-wild type tumors and are under active investigation across a spectrum of malignancies. …”
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Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics by Haisong Li, Can Li, Cong Fu, Yizhuo Wang, Tingting Liang, Haitao Wu, Chenxi Wu, Chang Wang, Tianmeng Sun, Shuhan Liu

“…Abstract Neutrophil extracellular traps (NETs) participate in both host defense and the pathogenesis of various diseases, such as infections, thrombosis, and tumors. While they help capture and eliminate pathogens, NETs’ excessive or dysregulated formation can lead to tissue damage and disease progression. …”
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Clinical Use of Dostarlimab in Advanced Stage and Recurrent Endometrial Cancer: Patient Selection and Perspectives by Bujnak AC, File B, Tewari KS

“…Advances in molecular tumor profiling have highlighted that a portion of EC tumors release high levels of neoantigens, indicating an opportunity to harness the immune system in therapeutic strategies. …”
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Identification and Validation of a Potential Stemness-Associated Biomarker in Hepatocellular Carcinoma by Yangyang Zhang, Ruike Zhang, Lingxiu Zeng, Haizhou Wang, Ruyi Peng, Meng Zhang, Hailin Zhang, Zhenwei Yang, Liping Gao, Meng Wang, Jing Liu

“…Cancer stem cells (CSCs) are typically related to metastasis, recurrence, and drug resistance in malignant tumors. However, the biomarker and mechanism of CSCs need further exploration. …”
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Germinoma with Involvement of Midline and Off-Midline Intracranial Structures by Monica Graciela Loto, Karina Danilowicz, Santiago González Abbati, Rafael Torino, Alejandro Misiunas

“…Germinomas are malignant intracranial germ tumors, usually found in suprasellar regions. Less than 10% are localized in off-middle structures, and synchronous involvement of both structures has only exceptionally been published. …”
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Diagnostic Value of Cytokeratin 17 during Oral Carcinogenesis: An Immunohistochemical Study by Sirima Sanguansin, Theerachai Kosanwat, Rachai Juengsomjit, Sopee Poomsawat

“…A significant association between CK17 expression and histopathologic differentiation of OSCC was found. Tumors with well differentiation had high CK17 expression compared with those of moderate and poor differentiation. …”
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Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia by Peiman Habibollahi, Todd Waldron, Pedram Heidari, Hoon Sung Cho, David Alcantara, Lee Josephson, Timothy C. Wang, Anil K. Rustgi, Umar Mahmood

“…Esophageal tumors provide unique challenges and opportunities for developing and testing surveillance imaging technology for different tumor microenvironment components, including assessment of immune cell modulation, with the ultimate goal of promoting early detection and response evaluation. …”
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Integrated bioinformatics analysis identifies ALDH18A1 as a prognostic hub gene in glutamine metabolism in lung adenocarcinoma by Hao Ren, Deng-Feng Ge, Zi-Chen Yang, Zhen-Ting Cheng, Shou-Xiang Zhao, Bin Zhang

“…Abstract Glutamine metabolism is pivotal in cancer biology, profoundly influencing tumor growth, proliferation, and resistance to therapies. …”
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Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case by Luca Apicella, Gianfranco Vallone, Sossio Vitale, Gianluca Garofalo, Luigi Russo, Riccardo Gallo, Stefano Federico, Massimo Sabbatini

“…The rarity of this affection, the need of a differential diagnosis with fat-containing tumors, and the possibility of parenchymal inflammation associated with RSL, potentially responsive to steroids, are also discussed.…”
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