-Tyrosine Confers Residualizing Properties to a -Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies by Fook T. Lee PhD, Ingrid J. G. Burvenich PhD, Nancy Guo MBBS, MSc, Pece Kocovski BSc (Honors), Henri Tochon-Danguy PhD, Uwe Ackermann PhD, Graeme J. O’Keefe PhD, Sylvia Gong PhD, Angela Rigopoulos BSc, MSc, Zhanqi Liu MBBS, PhD, Hui K. Gan MBBS, FRACP, PhD, Andrew M. Scott MBBS, FRACP, MD

“…Tumor uptake for 124 I-PEG 4 -tptddYddtpt-ch806 was similar to 111 In-CHX-A″-DTPA-ch806. …”
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ALDH1L2 drives HCC progression through TAM polarization by Jiajun Li, Chi Zhang, Qingqing Zhou, Qinqin Long, Jiayi Chen, Lili Meng, Wei Tian, Yue Yang, Chao Ge, Yuting Su, Xi-Dai Long, Jun Wu, Hua Tian

“…The interaction between tumor-associated macrophages and ALDH1L2-overexpressing HCC cells further promotes HCC progression. …”
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Individually moulded silicone dressing in full thickness skin grafts by Michael Götting, Rahel Zibell, Markus Jungehülsing

“…Charts of 24 patients who had undergone reconstruction with full thickness skin graft from the neck after surgery for skin tumors in the head from November 2017 to October 2020, were reviewed retrospectively to quantify the degree of post-operative graft loss and durability of the dressing. …”
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Strategies for preventing and managing osteoporosis in elderly breast cancer patients undergoing aromatase inhibitor therapy by Andi Tian, Chunyu Zhang

“…While AI effectively lower tumor recurrence rates, they are associated with adverse effects such as bone loss, osteoporosis, and increased risk of osteoporotic fractures. …”
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Stably Integrated for Assessment of Invasion Kinetics by Kelly N. Flentie, Min Qi, Seth T. Gammon, Yasmin Razia, Felix Lui, Luciano Marpegan, Aashish Manglik, David Piwnica-Worms, Jeffrey S. McKinney

“…Salmonella Typhimurium is a common cause of gastroenteritis in humans and also localizes to neoplastic tumors in animals. Invasion of specific eukaryotic cells is a key mechanism of Salmonella interactions with host tissues. …”
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Bile Duct Adenoma with Oncocytic Features by E. J. Johannesen, Zihao Wu, Jason-Scott Holly

“…The morphology, immunophenotype, presence of mucin, and normal appearing bile ducts, as well as the increased Ki67 proliferation rate, were consistent with a bile duct adenoma with oxyphilic (oncocytic) change. Oncocytic tumors in the liver are rare; the first described in 1992. …”
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Use of Autoantibodies to Detect the Onset of Breast Cancer by Jérôme Lacombe, Alain Mangé, Jérôme Solassol

“…Identification of tumor-specific markers capable of eliciting an immune response in the early stages of tumor development seems to provide an effective approach for early diagnosis. …”
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Recent Advances in Our Understanding of HLA-G Biology: Lessons from a Wide Spectrum of Human Diseases by Fabio Morandi, Roberta Rizzo, Enrico Fainardi, Nathalie Rouas-Freiss, Vito Pistoia

“…However, HLA-G can be expressed de novo at high levels in several pathological conditions, including solid and hematological tumors and during microbial or viral infections, leading to the impairment of the immune response against tumor cells or pathogens, respectively. …”
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Focal hand dystonia due to hemorrhage of the cervical spinal mass: a case report by Pelin Analay, Hazal Sevinç, Hilmi Berkan Abacıoğlu, Rahşan Göçmen, Bayram Kaymak, Levent Özçakar

“…Although dystonia is traditionally considered a disorder of the basal ganglia, it has been observed in association with lesions at various sites of the motor and sensory pathways, including spinal cord pathologies such as syringomyelia, tumors, and demyelinating lesions. However, there has been an increasing number of focal dystonia cases due to peripheral injuries, such as soft tissue trauma, mononeuropathy, plexopathy, and radiculopathy. …”
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PCSK9 in T-cell function and the immune response by Yuying Wang, Xiaosheng Fang, Jiarui Liu, Xiao Lv, Kang Lu, Yingxue Lu, Yujie Jiang

“…In recent years, increasing evidence has indicated other important roles for PCSK9 in inflammation, tumors, and even immune regulation. PCSK9 might be an attractive regulator of T-cell activation and expansion. …”
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PPARγ as a Novel Therapeutic Target in Lung Cancer by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…Its involvement in adipocyte differentiation and glucose and lipid homeostasis is well-recognized, but accumulating evidence now suggests that PPARγ may also function as a tumor suppressor, inhibiting development of primary tumors and metastases in lung cancer and other malignancies. …”
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Iodine-131 Metaiodobenzylguanidine Therapy for Neuroblastoma: Reports So Far and Future Perspective by Daiki Kayano, Seigo Kinuya

“…Neuroblastoma, which derives from neural crest, is the most common extracranial solid cancer in childhood. The tumors express the norepinephrine (NE) transporters on their cell membrane and take in metaiodobenzylguanidine (MIBG) via a NE transporter. …”
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Spatial stochastic models of cancer: Fitness, migration, invasion by Natalia L. Komarova

“…Cancer progression is driven by genetic and epigenetic events giving rise to heterogeneity of cellphenotypes, and by selection forces that shape the changingcomposition of tumors. The selection forces are dynamic and depend onmany factors. …”
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Atypical Presentation of Giant Mandibular Aneurysmal Bone Cyst with Cemento-Ossifying Fibroma Mimicking Sarcoma by Haneen Al-Maghrabi, Serge Verne, Bassam Al-Maghrabi, Osamah Almutawa, Jaudah Al-Maghrabi

“…We also discuss the most important pathologic differential diagnosis of tumors with malignant behavior and review the literature.…”
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Retrorectal Schwannomas: Atypical Presentation and Controversial Surgical Management by Wided Trimech, Farouk Ennaceur, Hiba Ben Hassine, Hanen Zneti, Faouzi Noomen, Khadija Zouari

“…Schwannomas also known as neurilemomas are benign tumors. Retrorectal schwannomas are extremely rare, accounting for 1 to 5% of all schwannomas. …”
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Primary Angiosarcoma of the Spleen: An Oncological Enigma by Myoteri Despoina, Dellaportas Dionysios, Ayiomamitis Georgios, Strigklis Konstantinos, Kouroumpas Efstratios, Zizi-Sermpetzoglou Adamantia

“…An 82-year-old woman was admitted with left pleural effusion and a palpable left upper quadrant abdominal mass, secondary to splenomegaly by two large splenic tumors. Classic open splenectomy was performed and angiosarcoma of the spleen was the final histopathological diagnosis, which was primary since no other disease site was revealed. …”
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Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway by Chao Chen, Qiwu Wang, Jiwen Liu

“…In addition, curcumin inhibited the tumor-related PI3K/Akt signaling pathway in CRPC cells. …”
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Skeletal Muscle Haemangioma: A Cause for Chronic Pain about the Knee: A Case Report by Kopuri Ravi Kiran, T. V. Suresh Babu, S. Suresh Babu, K. Deepti

“…Skeletal muscle haemangiomas are uncommon soft tissue tumors; more than 90% are misdiagnosed initially. …”
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Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy by Joseph Allencherril, Sebastian Bruera, Ronan Allencherril, Richard J. Hamill

“…HCC should be considered in cases of isolated tumors with unclear primaries as ectopic carcinogenesis and occult primary malignancy are possibilities.…”
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Premalignant Lesions in the Kidney by Ziva Kirkali, Kutsal Yorukoglu

“…Progression to invasive carcinoma is described in experimental cancer models, and in some human renal tumors. Similar molecular alterations are found in some putative premalignant changes. …”
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