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4101
Structural insights into antibody-based immunotherapy for hepatocellular carcinoma
Published 2025-01-01“…Several therapeutic antibodies that counter the immunosuppressive tumor microenvironment have demonstrated efficacy in clinical trials, leading to FDA approvals for advanced HCC treatment. …”
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4102
Huge Cystic Lymphangioma of the Pancreas Mimicking Pancreatic Cystic Neoplasm
Published 2012-01-01“…Lymphangiomas of the pancreas are very rare benign tumors of lymphatic origin, accounting for less than 1% of these neoplasms. …”
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4103
Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature
Published 2024-01-01“…Advances in this novel field of science have been closely linked to a deeper knowledge of tumor biology, particularly the intricate interplay between tumor cells, the immune system, and the tumor microenvironment (TME), which are central to cancer progression and immune evasion. …”
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4104
The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis.
Published 2021-10-01“…These in vivo and in vitro studies implicate MLX and other members of the proximal MYC network, such as MNT, in regulation of metabolism and differentiation, as well as in suppression of intrinsic and extrinsic death signaling pathways in both spermatogenesis and male germ cell tumors (MGCTs).…”
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4105
A rare giant renal angiomyolipoma in a 17-year-old male: A case report
Published 2025-01-01“…Renal angiomyolipoma is an uncommon benign tumor that mostly affects adults and is highly associated with tuberous sclerosis. …”
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4106
Dorsalis Pedis Free Flap: The Salvage Option following Failure of the Radial Forearm Flap in Total Lower Lip Reconstruction
Published 2014-01-01“…Reconstruction after resection of large tumors of the lower lip requires the use of free flaps in order to restore the shape and the function of the lip, with the free radial forearm flap being the most popular. …”
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4107
A Rare Case of Uterine Leiomyosarcoma with Metastasis to the Thyroid Gland
Published 2020-01-01“…Uterine leiomyosarcomas are aggressive tumors associated with a poor prognosis. These neoplasms have high metastatic potential, more frequently affecting the lungs, liver, and peritoneum. …”
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4108
Glioblastoma Multiforme Stem Cells
Published 2011-01-01“…Glioblastoma multiforme (GBM) is an aggressive, malignant, and lethal brain tumor, resistant to all current forms of treatment. …”
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4109
Orbital Cavernous Hemangioma Presenting with a Dome-Shaped Maculopathy-Like Appearance on Swept-Source Optical Tomography Imaging
Published 2020-01-01“…SS-OCT and SS-OCTA are important noninvasive tools for evaluating the retinal and choroidal effects in orbital tumors.…”
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4110
NK Cell Subtypes as Regulators of Autoimmune Liver Disease
Published 2016-01-01“…As major components of innate immunity, NK cells not only exert cell-mediated cytotoxicity to destroy tumors or infected cells, but also act to regulate the functions of other cells in the immune system by secreting cytokines and chemokines. …”
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4111
Biological Properties and the Role of IL-25 in Disease Pathogenesis
Published 2018-01-01“…By contrast, IL-17B is reported to be closely related to certain diseases, particularly tumors such as breast cancer, gastric cancer, and pancreatic cancer. …”
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4112
Primary Bone Lymphoma: A Case Series and Review of Literature
Published 2020-01-01“…The prevalence of PBL is estimated to be 3–7% amongst primary bone tumors and less than 2% amongst all lymphomas in adults. …”
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4113
Prognostic Parameters for the Primary Care of Melanoma Patients: What Is Really Risky in Melanoma?
Published 2011-01-01“…The identification of morphological surrogates and prognostic parameters in tumors with such genetic alteration seems therefore crucial when differentiating and classifying this heterogeneous tumor entity in more detail and thus facilitates the stratification of prognosis as well as therapy. …”
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4114
The application of series multi-pooling convolutional neural networks for medical image segmentation
Published 2017-12-01“…It is crucial to precisely classify the pixels in brain tumor tissues in the brain tumor image segmentation. …”
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4115
Radioresistance in rectal cancer: can nanoparticles turn the tide?
Published 2025-01-01“…Here, we revise the main molecular differences between rectal and colon tumors, exploring the complex orchestration beyond rectal cancer radioresistance and the most promising nanomedicines reported in the literature to improve neoadjuvant therapy response rates. …”
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4116
Profile of STING agonist and inhibitor research: a bibliometric analysis
Published 2025-02-01“…BackgroundSTING is a core signaling hub molecule in the innate immune system, involved in various diseases, including infectious diseases, autoimmune diseases, tumors, aging, organ fibrosis, and neurodegenerative diseases. …”
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4117
Pigmented Nodular Basal Cell Carcinomas in Differential Diagnosis with Nodular Melanomas: Confocal Microscopy as a Reliable Tool for In Vivo Histologic Diagnosis
Published 2011-01-01“…Reflectance confocal microscopy is a relatively new imaging technique that permits to evaluate in vivo skin tumors with a nearly histological resolution. Here, we present four cases of challenging nodular lesions where confocal microscopy was able to clarify the diagnosis.…”
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4118
Diagnostic Accuracy of NICE Classification System for Optical Recognition of Predictive Morphology of Colorectal Polyps
Published 2018-01-01“…The NICE classification is an international endoscopic classification of colorectal neoplasia through a narrowband spectrum that on the basis of lesion colors, vascular pattern, and structure of the surface of the mucous membrane classifies colorectal neoplasms in three categories: type 1 as hyperplastic lesions, type 2 as adenomas, and type 3 as invasive tumors. The aim of this study was to verify diagnostic accuracy of the NICE classification system compared to the reference standard: histopathological analysis. …”
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4119
Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
Published 2015-01-01“…Its clinical behavior is similar to serous borderline tumors with relatively favorable prognosis. We report herein a case of a 60-year-old postmenopausal woman who presented with abdominal distension. …”
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4120
Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines
Published 2016-01-01“…Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium. …”
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