Malignant Pleural Mesothelioma. Case Report and Literature Review by Samuel Sánchez Sánchez, Liz María Calvo Díaz, Ana Laura Navarro Baldellot

“…Pleural mesotheliomas are primary mesothelial cell tumors. Lining the pleural cavity, they are closely related to asbestos exposure. …”
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Controversies in the Management of Endometrial Cancer by V. Masciullo, G. Amadio, D. Lo Russo, I. Raimondo, A. Giordano, G. Scambia

“…This review summarizes the management of EC and discusses current controversies regarding the role of lymphadenectomy and radiotherapy in patients with intermediate-risk tumors confined to the uterus.…”
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Regulatory role of PPAR in colorectal cancer by Cong Wang, Tingcong Lv, Binghui Jin, Yang Li, Zhe Fan

“…Abstract Colorectal cancer (CRC) is one of the most common tumors in the digestive system, and the majority of patients are found to be in advanced stages, which is a burden to human health all over the world. …”
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Case Report of Synchronous Prostate, Hepatocellular, and Rectal Carcinomas and Review of the Literature by Viktoria Lamprou, Daniel Paramythiotis, Dimitrios Giakoustidis, Anestis Karakatsanis, Athanasios Astreinidis, Moysis Moysidis, Antonios Mihalopoulos, Stefanos Finitsis

“…Synchronous occurrence of three histopathologically distinct malignant tumors is a rare event, and there are no definitive guidelines about the optimal treatment of these patients. …”
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Diffuse Pancreatic Carcinoma with Hepatic Metastases by Hoang Quan Nguyen, Ngoc Trinh Thi Pham, Van Trung Hoang, Hoang Anh Thi Van, Chinh Huynh, Duc Thanh Hoang

“…The purpose of this article is to present a case of a 54-year-old male with pancreatic cancer and to review the epidemiology, diagnosis, management, and prevention of pancreatic tumors in general as well as pancreatic carcinoma in particular.…”
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Meningiomatosis Restricted to the Left Cerebral Hemisphere Presenting with Frontal Lobe Seizure: A Short Communication by Biniyam A. Ayele, Hilina Dagnachew, Meskerem Nimani, Jarsso Tadesse Hirbu

“… Seizures are a common clinical feature of benign intracranial brain tumors such as meningioma. Although seizures are cortical phenomena that typically originate from lesions affecting cortical neurons, meningiomas, which arise from the meningeal lining, can still induce seizures due to their proximity to the cerebral cortex. …”
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A Fibromatosis Case Mimicking Abdominal Aorta Aneurysm by Arzu Tasdemir, Cemal Kahraman, Kutay Tasdemir, Ertugrul Mavili

“…Diagnosis can be established with arteriography, tomography, or magnetic resonance imaging associated with clinical findings. Tumors and cysts should be considered in differential diagnosis. …”
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Synchronous Diagnosis of Multiple Myeloma, Breast Cancer, and Monoclonal B-Cell Lymphocytosis on Initial Presentation by A. Vennepureddy, V. Motilal Nehru, Y. Liu, F. Mohammad, J. P. Atallah

“…Successful management of the patient and increased life expectancy can be achieved by multidisciplinary management and patient-oriented approach in multiple primary malignant synchronous tumors.…”
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Five Cases of Non-Hodgkin B-Cell Lymphoma of the Ovary by Taylan Senol, Emek Doger, Ilker Kahramanoglu, Ayfer Geduk, Emre Kole, Izzet Yucesoy, Eray Caliskan

“…Ovarian lymphoma can mimic more frequently occurring tumors including advanced epithelial carcinoma and radical surgery may be performed instead of a biopsy. …”
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Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures by Shengjie Cui, Jing Han, Binny Khandakar, Barak Friedman, Domingo Nunez, Gabriel A. Sara, Gabriel S. Levi

“…Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. …”
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New Antibody Conjugates in Cancer Therapy by Serengulam V. Govindan, David M. Goldenberg

“…The advantage of pretargeted RAIT over directly labeled MAbs is continuing to be validated in preclinical models of lymphoma and solid tumors. Importantly, the advantages of combining RAIT with radiation sensitizers, with immunotherapy, or a drug conjugate targeting a different antigen are being studied clinically and preclinically. …”
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The Ultrasound-Based Diagnosis of Sudden Scrotal Enlargement in an Infant: A Case Report by Bartosz Rutka, Martyna Rutka, Adam Niedziela, Dominik Domoń

“… Scrotal enlargement in infants has a variety of causes, ranging from benign conditions like hydrocele to more serious issues such as scrotal hernias or testicular tumors. We present the case of a 3-month-old infant with progressive right-sided scrotal swelling, diagnosed with a scrotal hernia through an urgent ultrasound examination. …”
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A pivotal decade for bispecific antibodies? by Marlena Surowka, Christian Klein

“…In the 2020s, the approval of additional bsAbs can be expected in hematological malignancies, solid tumors and non-oncology indications, establishing bsAbs as essential part of the therapeutic armamentarium.…”
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Ectopic Tooth in Mandibular Canal, Maxillary Sinus, and Mandibular Condyle by Mert Akbas, Zülfikar Karabıyık, Altan Varol

“…It was reported that odontogenic tumors and cysts can develop around the ectopic tooth. …”
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Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins by Maria Angelica Freitas-Cortez, Fatemeh Masrorpour, Hong Jiang, Iqbal Mahmud, Yue Lu, Ailing Huang, Lisa K. Duong, Qi Wang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Bo Wei, Wai-Kin Chan, Kevin Lin, Jie Zhang, Efrosini Tsouko, Shonik Ganjoo, Hampartsoum B. Barsoumian, Thomas S. Riad, Yun Hu, Carola Leuschner, Nahum Puebla-Osorio, Jing Wang, Jian Hu, Michael A. Davies, Vinay K. Puduvalli, Cyrielle Billon, Thomas P. Burris, Philip L. Lorenzi, Boyi Gan, James W. Welsh

“…Abstract Background Cancer creates an immunosuppressive environment that hampers immune responses, allowing tumors to grow and resist therapy. One way the immune system fights back is by inducing ferroptosis, a type of cell death, in tumor cells through CD8 + T cells. …”
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Kinomic profiling to predict sunitinib response of patients with metastasized clear cell Renal Cell Carcinoma by Jeannette C. Oosterwijk-Wakka, Liesbeth Houkes, Loes F.M. van der Zanden, Lambertus A.L.M. Kiemeney, Kerstin Junker, Anne Y Warren, Tim Eisen, Ulrich Jaehde, Marius T Radu, Rob Ruijtenbeek, Egbert Oosterwijk

“…Discussion/Conclusion: Based on kinase levels ccRCC tumors can be subdivided into 3 clusters which may reflect the aggressiveness of these tumors. …”
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MOF-derived intelligent arenobufagin nanocomposites with glucose metabolism inhibition for enhanced bioenergetic therapy and integrated photothermal-chemodynamic-chemotherapy by Lihua Chen, Jiaying Yang, Lingyu Jia, Xiaolu Wei, Huijun Wang, Zhuo Liu, Shan Jiang, Pengyue Li, Yanyan Zhou, Hongjie Wang, Nan Si, Baolin Bian, Qinghe Zhao, Haiyu Zhao

“…Abstract Bioenergetic therapy based on tumor glucose metabolism is emerging as a promising therapeutic modality. …”
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Serum NLR combined with CA125 and HE4 improves the diagnostic and prognostic efficiency in patients with ovarian cancer by Yun Tian, Yun Tian, Xiabing Li, Xiabing Li, Hongjian Zhang, Hongjian Zhang, Yaping Wang, Yaping Wang, Hongyu Li, Hongyu Li, Qiaohong Qin, Qiaohong Qin

“…This study seeks to identify combination diagnostic and prognostic markers for OC, aiming to improve diagnostic and prognostic efficacy, especially in the early stages.MethodsWe analyzed the targeted biomarkers in a cohort of 104 OC patients and 100 controls, which comprised 50 patients with benign ovarian tumors and 50 healthy women, using enzyme-linked immunosorbent assay (ELISA) and complete blood counting (CBC). …”
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Novel combination strategy of high intensity focused ultrasound (HIFU) and checkpoint blockade boosted by bioinspired and oxygen-supplied nanoprobe for multimodal imaging-guided ca... by Ying Zhou, Chen Cheng, Qi Wang, Min Zheng, Pan Li, Yang Zhou, Yuting Cao, Li Wan, Xun Guo, Xiaohong Lin, Rui Tang, Hongye He, Nianhong Wu, Qiaoqi Chen, Yaqin Hu, Xialin Xiong, Faqi Li

“…Moreover, HIFU ablation alone may inevitably lead to the presence of residual tumors, which may cause tumor recurrence and metastasis. …”
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Durvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II study by Pernelle Lavaud, Esma Saada-Bouzid, Renaud Sabatier, Olivia Le Saux, Thibault de la Motte Rouge, Anthony Gonçalves, Elodie Coquan, Jean-Sébastien Frenel, Marta Jiménez, Alice Hervieu, Laurent Mathiot, François Legrand, Claire Cropet, Edith Borcoman, Emmanuelle Charafe

“…The primary efficacy endpoint was the clinical benefit rate (CBR) based on the Response Evaluation Criteria in Solid Tumors V.1.1, which was analyzed using a Bayesian approachResults A total of 31 patients were enrolled and treated in the cervical cancer cohort. …”
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