Two Cases of Allergic Fungal Sinusitis with Differing Postoperative Course by Yuma Matsumoto, Hidenori Yokoi, Michitsugu Kawada, Masachika Fujiwara, Koichiro Saito

“…Allergic fungal sinusitis (AFS) often develops in unilateral paranasal sinuses, which must be differentiated from tumors. When AFS develops on both sides, however, it must be differentiated from eosinophilic chronic sinusitis with evident eosinophilic infiltration at nasal/paranasal sinus mucosa; both conditions are highly recurrent and commonly considered intractable paranasal sinusitis. …”
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The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models by Adam B. Glick

“…TGFβ signaling is tightly regulated in normal tissues and becomes deregulated during cancer development in cutaneous SCC and many other solid tumors. Because of these diverse biological processes regulated by TGFβ1, this cytokine and its signaling pathway appear to function at multiple points during carcinogenesis with distinct effects. …”
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Pulmonary Blastoma: A Rare Primary Lung Malignancy by Mahmoud S. Alahwal, Iqbal H. Maniyar, Faiza Saleem, Mariam Alshiekh

“…Pulmonary blastoma, a rare primary lung malignancy, is considered to be distinct from other lung tumors based on pathological features, clinical course, and prognosis. …”
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Hyaluronic Acid-Based Drug Delivery Systems for Cancer Therapy by Ekaterina Pashkina, Maria Bykova, Maria Berishvili, Yaroslav Lazarev, Vladimir Kozlov

“…This review examines the role of HA and its receptors in health and tumors and analyzes existing HA-based delivery systems and their use in various types of cancer. …”
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A Primer on the Role of TP53 Mutation and Targeted Therapy in Endometrial Cancer by Bohao Zhang, Haozhe Zhang, Yanru Qin

“…TP53 mutation, in particular, can lead to the dysfunction of numerous regulatory factors and alteration of the tumor microenvironment (TME). The changes in the TME subsequently promote the development of tumors and assist in immune escape by tumor cells, making it more challenging to treat EC and resulting in a poor prognosis. …”
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Combined Cerebellar and Spinal Cord Deficits Caused by an Underlying Gynecologic Malignancy by Tamer Othman, Moshe-Samuel Hendizadeh, Ritika Vankina, Susan Park, Phyllis Kim

“…Neurologic symptoms frequently precede the cancer diagnosis, which is most often seen in women with breast or gynecologic tumors. Anti-Yo-related PCD is the most common PCD syndrome, and one of the best understood. …”
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MELANOMAS, SARCOMAS, AND RENAL METASTASES IN THE LIVER: HOW TO TREAT? by Angelica Maria LUCCHESE, Antonio Nocchi KALIL, Alessandro L. DINIZ, Karl J. OLDHAFER, Timothy M. PAWLIK, René ADAM, Olivier SOUBRANE, Maria Ignez BRAGHIROLI, Ricardo Lemos COTTA-PEREIRA

“…ABSTRACT Liver metastases from melanomas, sarcomas, and renal tumors are less frequent. Treatment and prognosis will depend on whether they are isolated or multiple, size and location, the presence or absence of extrahepatic neoplastic disease, age, stage of the initial disease, initial treatments instituted, time of evolution, and clinical condition of the patient. …”
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Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation by Theresa Placke, Hans-Georg Kopp, Helmut Rainer Salih

“…The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. …”
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P53 and PIK3CA Mutations in KRAS/HER2 Negative Ovarian Intestinal-Type Mucinous Carcinoma Associated with Mature Teratoma by Sarah Bouri, Philippe Simon, Nicky D’Haene, Xavier Catteau, Jean-Christophe Noël

“…The molecular profile of these tumors is still controversial. We report here the first case of mucinous ovarian tumor in which mutation of the PIK3CA and P53 genes could be demonstrated by the next generation sequencing technique without KRAS mutation or HER2 amplification. …”
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Surgical Treatment of Jacob’s Disease: A Case Report Involving an Osteochondroma of the Coronoid Process by Dale E. Stringer, Kourt B. Chatelain, Rahul Tandon

“…Although it is one of the most common benign tumors of bone in the axial skeleton, the osteochondroma is relatively rare in the maxillofacial region. …”
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Research progress of artificial intelligence in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer by Wei Wei, Menghang Ma, Zhenyu Liu

“…In clinical diagnostics, medical imaging has emerged as a critical tool for delineating the structural transformations within breast cancer tumors resulting from pharmacological interventions. …”
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A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment by Emanuele Grasso, Fabio Marino, Michele Bottalico, Michele Simone

“…Retroperitoneal sarcomas are rare neoplasms that account for only 1%-2% of all solid tumors and liposarcomas represent the most frequent histological type. …”
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Intraosseous Hemangioma of the Middle Turbinate Misdiagnosed As a Nasal Polyp by Tae Hoon Kim, Eun Jung Lim, Jun-Ki Lee, Jin Gul Lee, Man-Hoon Han

“…Intraosseous hemangiomas account for 1% of all bone tumors and primarily originate from the vertebral column and skull bones. …”
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Research Advances in Antitumor Mechanism of Evodiamine by Luning Li, Cunxin Zhang, Chen Huang, Xinchen Tian, Wenxue Sun, Shulong Jiang

“…In recent years, it has been found that evodiamine has tumor-suppressive effects on a variety of tumors. …”
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Thyroid Carcinoma. Case Report and Literature Review by José Alberto Puerto Lorenzo, Lidia Torres Aja, Eslinda Cabanes Rojas

“…Mucinous thyroid carcinomas are very rare and in some cases may appear in association with other tumors, but it does not represent a true primary thyroid carcinoma. …”
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Leiomyoma of the Round Ligament of the Uterus Mimicking Inguinal Hernia by Ioulia Maria Christodoulou, Argiris Angelopoulos, Petros Siaperas, Argyrios Ioannidis, Andreas Skarpas, Antreas Tellos, Georgios Velimezis, Ioannis Karanikas

“…Leiomyomas are benign tumors, which can present as hernias, lymph nodes, or other inguinal masses. …”
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Burkitt Lymphoma of the Duodenum: An Uncommon Phenomenon by Fahad Malik, Manuel Gonzalez, Wahib Zafar

“…Burkitt lymphoma is an aggressively growing tumor commonly found in African children, involving the jaw and facial bones. …”
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Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature by Mehmet Fatih Haskaraca, Mustafa Ozsoy, İsmail Özsan, Kamile Kurt

“…Histopathologic evaluation of the surgical specimen after laparoscopic cholecystectomy revealed malign epithelial tumor consisting of atypical cells with large eosinophilic cytoplasm and dense melanin pigment within the cytoplasm of the tumor cells. …”
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Patient-Tailored, Imaging-Guided, Long-Term Temozolomide Chemotherapy in Patients with Glioblastoma by Norbert Galldiks, Lutz W. Kracht, Lothar Burghaus, Roland T. Ullrich, Heiko Backes, Anna Brunn, Wolf-Dieter Heiss, Andreas H. Jacobs

“…In these patients, repeated MET-and FLT-PET imaging documented complete response to the initial treatment regimen, including resection, radiation, and TMZ, and during the course of the disease, recurrent, uncontrollable tumor activity. Continuation or dose escalation of TMZ in both patients was shown to be ineffective to overcome the metabolic activity of the tumor. …”
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Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review by Raghunandan Venkat, Marlon A. Guerrero

“…While surgery has remained the cornerstone of management of these tumors, the surgical approach has seen numerous innovations over the past few decades. …”
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