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3721
FN1 shapes the behavior of papillary thyroid carcinoma through alternative splicing of EDB region
Published 2025-01-01“…Abstract Papillary thyroid cancer (PTC) is often characterized by indolent behavior, small tumors with slow cell proliferation and a tendency to metastasize to cervical lymph node simultaneously, and the molecular mechanisms underlying that remain poorly understood. …”
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3722
In vivo MRS study of long-term effects of traumatic intracranial injection of a culture medium in mice
Published 2023-11-01“…Orthotopic transplantation of glioblastoma cells in the brain of laboratory mice is a common animal model for studying brain tumors. It was shown that 1H magnetic resonance spectroscopy (MRS) enables monitoring of the tumor’s occurrence and its development during therapy based on the ratio of several metabolites. …”
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3723
Anterior skull base reconstruction using nasoseptal flap: cadaveric feasibility study and clinical implication [SevEN-001]
Published 2020-09-01“…Based on these findings, defects resulting from an endoscopic resection of ASB tumors were reconstructed using PNSF without total sphenoidotomy in 3 patients. …”
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3724
Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin
Published 2025-01-01“…CCG-257081 reduced proliferation and activated caspase-3 in YUMMER_R melanoma tumors. Both CCG-257081 enantiomers robustly suppressed development of Vem-resistant colonies with the S isomer being more potent (1 μM IC50).ConclusionCCG-257081 appears to target pre-resistant cells and Vem-induced resistant cells through enhanced apoptosis. …”
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3725
ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data
Published 2024-11-01“…Metastases are the leading cause of death from malignant tumors. The metastatic process involves the exit of cancer cells from the primary tumor into the blood or other transport system, colonization and proliferation in a distant organ. …”
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3726
Progress in the Study of Intratumoral Microorganisms in Hepatocellular Carcinoma
Published 2025-01-01“…This comprehensive review aims to address this gap by summarizing research progress related to in the field of hepatocellular carcinoma intratumoral bacteria, including their sources, types, distribution characteristics within tumors, impact on tumor development, underlying mechanisms, and application prospects. …”
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3727
Preoperative CT-based radiomics nomogram to predict the micropapillary pattern in lung adenocarcinoma of size 2 cm or less
Published 2025-01-01“…The region of interest of the tumor was delineated on the computed tomography (CT) images, and radiomics features were extracted. …”
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3728
Preoperative Quality of Life in Patients with Small Vestibular Schwannomas
Published 2024-11-01“…Background: Vestibular schwannomas (VS) are benign tumors arising from the eighth cranial nerve. They often cause no symptoms for a long period of time. …”
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3729
Extrapolating Prognostic Factors of Primary Curative Resection to Postresection Recurrences Hepatocellular Carcinoma Treatable by Radiofrequency Ablation
Published 2021-01-01“…In this retrospective study, we assessed 235 patients who underwent limited RFA of HCC recurrences (tumors≤5 cm; nodules≤3) after primary curative resection. …”
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3730
Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review
Published 2025-02-01“…In clinical use, bevacizumab has improved the overall survival (OS) and progression-free survival (PFS) of malignant solid tumors, and the safe use of bevacizumab has gradually become the mainstream direction of clinical, nursing and pharmaceutical research. …”
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3731
MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma
Published 2022-01-01“…Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. …”
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3732
Outcomes of Surgical Treatment of Multiple Primary Colorectal and Prostate Cancer
Published 2025-02-01“…The history of surgical treatment of one of the tumors is not a contraindication for the use of minimally invasive techniques, however, the choice of surgical approach should be individualized. …”
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3733
Needle tracking and segmentation in breast ultrasound imaging based on spatio-temporal memory network
Published 2025-01-01“…IntroductionUltrasound-guided needle biopsy is a commonly employed technique in modern medicine for obtaining tissue samples, such as those from breast tumors, for pathological analysis. However, it is limited by the low signal-to-noise ratio and the complex background of breast ultrasound imaging. …”
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3734
Transcriptomic-Based Identification of miR-125a Novel Targets in Human Hepatocarcinoma Cells
Published 2025-01-01“…Hepatocellular carcinoma (HCC) is among the most aggressive and lethal human tumors. Many functional studies have demonstrated the role of non-coding RNAs (ncRNA), particularly microRNAs (miRNA), in the regulation of hepatocarcinogenesis driving pathways. …”
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3735
Multifocality and Detectability of Prostate Cancer with 3-Tesla Multiparametric Magnetic Resonance Imaging: Correlation with Radical Prostatectomy Mapping Histopathology
Published 2024-01-01“…According to the multivariate analysis, only tumor size and Gleason Score (GS) were independent predictors regarding the ability of mpMRI to detect tumor foci within the prostate (p<0.0001). …”
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3736
Assessment of targets of antibody drug conjugates in SCLC
Published 2025-01-01“…Abstract Antibody-drug conjugate (ADC) therapy has transformed treatment for several solid tumors, including small cell lung cancer (SCLC). However, significant challenges remain, including systemic toxicity, acquired resistance, and the lack of reliable biomarkers for patient selection. …”
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3737
Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment
Published 2025-01-01“…In a murine melanoma model, we demonstrated that ICFESs indeed targeted homologous tumors with prolonged intratumoral retention compared with free ICG in vivo. …”
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3738
Synovial sarcoma. Evaluation of Prognosis with Emphasis on the Study of DNA Ploidy and Proliferation (PCNA and Ki-67) Markers
Published 1998-01-01“…Forty-nine cases of previously untreated primary SS (23 females and 26 males, ranging in age from 7 to 81, with 31 tumors located in the lower extremity, 8 at the upper extremity and 10 at the trunchus), without regional lymph-node or distant metastases were studied. …”
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3739
Synovial sarcoma: A radiologic case report
Published 2025-03-01“…Synovial sarcoma is a common but aggressive subset of sarcomatous tumors that often arises adjacent to the large joints of extremities. …”
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3740
Paracolpium Leiomyoma Misdiagnosed as Endometriosis: Case Report and Surgical Technique of a Laparoscopic Approach
Published 2022-01-01“…This case report describes the technique for laparoscopic approach to paracolpium tumors.…”
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