Primary multiple cancer in practice of urological oncologist by M. D. Ter-Ovanesov, D. M. Yagudaev, A. A. Gritskevich, E. V. Anikanova, K. I. Medvedev

“…Primary multiple malignancies (PMMs) are defined as two or more malignant tumors of various pathogenic origin detected simultaneously or sequentially in one patient. …”
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Immunohistochemical Coexpression of Epithelial Cell Adhesion Molecule and Alpha-Fetoprotein in Hepatocellular Carcinoma by Leonardo do Prado Lima, Carla Jorge Machado, João Bernardo Sancio Rocha Rodrigues, Leonardo de Souza Vasconcellos, Eduardo Paulino Junior, Paula Vieira Teixeira Vidigal, Vivian Resende

“…A significant difference was observed in the ratio between the different phenotypes (p = 0.002), identifying 12 (29.3%) EPCAM positive tumors and 29 (70.7%) negative tumors. EpCAM+ expression was associated with AFP + (OR = 12.5, 95% CI, 1.9-84.1, p<0.001). …”
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Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1 by Baocheng Xie, Peishan Wu, Hongyu Liu, XiangDi Yang, Linxuan Huang

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ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis by Guro E. Lind, Kristine Kleivi, Gunn I. Meling, Manuel R. Teixeira, Espen Thiis-Evensen, Torleiv O. Rognum, Ragnhild A. Lothe

“…These genes were unmethylated in tumors (n=82) from three other organs, prostate, testis, and kidney. …”
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A Rare Presentation of Stage IV Large Cell Neuroendocrine Carcinoma of the Cervix with Metastasis to the Cranium by Neema Hooker, Sveta Mohanan, R. Tucker Burks

“…Neuroendocrine tumors (NETs) are aggressive diseases developing from neuroendocrine cells that most frequently involve the gastro-entero-pancreatic tract and the lung, but more rarely are found in almost all body tissues. …”
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Malignant Transformation of a Mature Cystic Ovarian Teratoma into Thyroid Carcinoma, Mucinous Adenocarcinoma, and Strumal Carcinoid: A Case Report and Literature Review by Hilary D. Hinshaw, Ashlee L. Smith, Mohamed Mokhtar Desouki, Alexander B. Olawaiye

“…Additionally, extrapolating from data for mucinous adenocarcinomas, consideration could be given to adjuvant chemotherapy after appropriate staging (b). Strumal carcinoid tumors should be treated as tumors of low malignant potential. …”
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Advancing pancreatic cancer research and therapeutics: the transformative role of organoid technology by Jihao Xu, Minh Duc Pham, Vincenzo Corbo, Mariano Ponz-Sarvise, Tobiloba Oni, Daniel Öhlund, Chang-Il Hwang

“…We explore the applications of pancreatic organoids in dissecting the tumor microenvironment (TME); elucidating cancer progression, metastasis, and drug resistance mechanisms; and personalizing therapeutic strategies. …”
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Emerging Prospects for Nanoparticle-Enabled Cancer Immunotherapy by Manal Ali Buabeid, El-Shaimaa A. Arafa, Ghulam Murtaza

“…Conversely, in solid tumors, tumor microenvironment suppresses the immune system leading to the evasion of anticancer immunity. …”
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Acute Tracheal Obstruction Secondary to Cervical Liposarcoma Metastasis by Haoyu Chen, Song Zhang, Haining Zhou

“…Although CT scans are helpful in identifying intrabronchial tumors, bronchoscopy remains the gold standard for diagnosis and treatment, with several options available for urgent cases.…”
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In Vivo Imaging of Retinoic Acid Receptor Activity using a Sodium/Iodide Symporter and Luciferase Dual Imaging Reporter Gene by Min Kyung So, Joo Hyun Kang, June-Key Chung, Yong Jin Lee, Jae Hoon Shin, Kwang Il Kim, Jae Min Jeong, Dong Soo Lee, Myung Chul Lee

“…In vivo luciferase images showed higher intensity in retinoic acid treated SK-RARE/NL tumors, and scintigraphic images of SK-RARE/NL tumors showed increased Tc-99m uptake after retinoic acid treatment. …”
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Assessment of Molecular Imaging of Angiogenesis with Three-Dimensional Ultrasonography by Jason E. Streeter, Ryan C. Gessner, James Tsuruta, Steven Feingold, Paul A. Dayton

“…Molecular imaging (MI) with ultrasonography relies on microbubble contrast agents (MCAs) adhering to a ligand-specific target for applications such as characterizing tumor angiogenesis. It is projected that ultrasonic (US) MI can provide information about tumor therapeutic response before the detection of phenotypic changes. …”
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Pleomorphic adenoma of the parapharyngeal space by Anas Douami, Oussama Marsafi, Aicha Merzem, Hasnaa Belgadir, Omar Amriss, Nadia Moussali, Naima Elbenna

“…Pleomorphic adenoma of the parapharyngeal space is a rare benign tumor, representing less than 1% of tumors of the parapharyngeal space. …”
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Simultaneous Bilateral Spontaneous Pneumothorax Revealed Birt-Hogg-Dubè Syndrome by Alessandro Tamburrini, Francesco Sellitri, Federico Tacconi, Francesco Brancati, Tommaso Claudio Mineo

“…An underlying lung disease has been commonly described; in most istances primary or secondary tumors, interstitial diseases, and infectious diseases. …”
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A New Case of Spontaneous Regression of Inflammatory Hepatic Pseudotumor by Hichem Jerraya, Slim Jarboui, Hassen Daghmoura, Abdeljelil Zaouche

“…Introduction. Inflammatory pseudo-tumors (IPT) of the liver are rare and difficult to diagnose, because mimicking malignant tumors. …”
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Cellular Senescence as a Target in Cancer Control by Mar Vergel, Juan J. Marin, Purificacion Estevez, Amancio Carnero

“…Recent findings suggest that cellular senescence is a natural mechanism to prevent undesired oncogenic stress in somatic cells that has been lost in malignant tumors. Given that the ultimate goal of cancer research is to find the definitive cure for as many tumor types as possible, exploration of cellular senescence to drive towards antitumor therapies may decisively influence the outcome of new drugs. …”
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Exploring the Crosstalk between Inflammation and Epithelial-Mesenchymal Transition in Cancer by Indranil Chattopadhyay, Rangarao Ambati, Rohit Gundamaraju

“…T and B cells, dendritic cells (DCs), and tumor-associated macrophages (TAMs) which are present in the tumor microenvironment induce EMT. …”
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The Relationship Between the Modulation of Intestinal Microbiota and the Response to Immunotherapy in Patients with Cancer by Laura Radoš, Marin Golčić, Ivana Mikolašević

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Interactions between key genes and pathways in prostate cancer progression and therapy resistance by Fan Wu, Hengsen Zhang, Miaomiao Hao

“…Prostate cancer is one of the most prevalent malignant tumors in men, particularly in regions with a high Human Development Index. …”
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Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases by Omer Sefvan Janjua, Sana Mehmood Qureshi

“…Out of these records, tumors with a diagnosis of BCC in the head and neck region were retrieved and separated. …”
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Intraoperative Imaging of Positron Emission Tomographic Radiotracers Using Cerenkov Luminescence Emissions by Jason P. Holland, Guillaume Normand, Alessandro Ruggiero, Jason S. Lewis, Jan Grimm

“…Here we report the full characterization of CLI using the positron-emitting radiotracer 89 Zr-DFO-trastuzumab for target-specific, quantitative imaging of HER2/neu -positive tumors in vivo. We also provide the first demonstration of the feasibility of using CLI for true image-guided, intraoperative surgical resection of tumors. …”
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