Tumor cells escape immunosurveillance by hampering LFA-1 by Shishir Upadhyay, Lewis Murugu, Lena Svensson, Lena Svensson

“…During tumor immunosurveillance, leukocytes play a crucial role in the cellular defense system, working collaboratively with other immune components to recognize and eliminate aberrant cells. …”
Get full text

Pancreatic Neuroendocrine Tumor in the Setting of Dorsal Agenesis of the Pancreas by Samih Nassif, Cecilia Ponchiardi, Teviah Sachs

“…We present the case of a pancreatic neuroendocrine tumor in a patient with dorsal agenesis of the pancreas, with a review of the related literature.…”
Get full text

Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura by Charalampos Mavridis, George Georgiadis, Eleni D. Lagoudaki, Iordanis Skamagkas, Ioannis Heretis, Anastasios V. Koutsopoulos, Charalampos Mamoulakis

“…Bladder leiomyomas (BLs) are extremely rare benign tumors of mesenchymal origin. The exact pathophysiological mechanisms that lead to their appearance remain unclear including hormonal disorders, chromosomal abnormalities, and fetal remnants in the bladder. …”
Get full text

Jejunal Intussusception: A Rare Presentation of Carcinoid Tumor by Umashankkar Kannan, Amir A. Rahnemai-Azar, Ashish N. Patel, Vinaya Gaduputi, Ajay K. Shah

Get full text

Paratesticular Serous Borderline Tumor in a Pediatric Patient by Itzel Araceli Ortiz Meza, Marco Antonio Ponce Camacho, Rodolfo Franco Márquez, Mauricio Delgado Morquecho, Raquel Garza Guajardo, Oralia Barboza Quintana

“…Tumors of the paratesticular region are generally tumors of slow growth, with little symptomatology and, in most cases, benign in nature; in this area, a borderline serous tumor may arise hypothetically from Müllerian metaplasia of the tunica vaginalis, which is histologically identical to its ovarian counterpart. …”
Get full text

The Roles of Fibroblast Growth Factors in the Testicular Development and Tumor by Xin Jiang, Melissa Skibba, Chi Zhang, Yi Tan, Ying Xin, Yaqin Qu

“…This review summarizes the structure and fuctions of testis, the roles of FGFs on testicular development and potential involvement in testicular tumor and its regulatory mechanism. Among 23 members of FGFs, the FGF-1, FGF-2, FGF-4, FGF-8, FGF-9, and FGF-21 were involved and describe in details. …”
Get full text

Paratesticular Inflammatory Myofibroblastic Tumor in a Pediatric Patient by Miriam Harel, John H. Makari

“…Although rare, paratesticular inflammatory myofibroblastic tumor (IMT) represents the second most common paratesticular mass after adenomatoid tumor and comprises roughly 6% of such lesions. …”
Get full text

Adrenal Lymphangioma Masquerading as a Catecholamine Producing Tumor by Israel Hodish, Lindsay Schmidt, Andreas G. Moraitis

Get full text

Two Years of Gynecomastia Caused by Leydig Cell Tumor by Philip Zeuschner, Christian Veith, Johannes Linxweiler, Michael Stöckle, Julia Heinzelbecker

“…In rare cases, it results from Leydig cell tumors, a rare entity accounting for 3% of all testicular neoplasms. …”
Get full text

Behavioral phenotyping of mice deficient for tumor necrosis factor by D. V. Fursenko, N. V. Khotskin, V. A. Kulikov, A. V. Kulikov

Subjects: “…tumor necrosis factor…”
Get full text

Do Not Miss the Tumor: A Novel Presentation of Osteosarcoma by Michael DePalma, Sachin Gupta, Jie Nguyen, Divya Talwar, Alexandre Arkader, Lawrence Wells

Get full text

Cardiac Myxoid Spindle Cell Tumor in a Neonate by Reza Abbaszadeh, Fatemeh Naderi, Amir Hossein Jalali, Yaser Toloueitabar

“…Introduction: Different subtypes of cardiac tumors containing spindle cells have been described as cardiac sarcoma. …”
Get full text

Papillary Endolymphatic Sac Tumor: A Case Report by S. Arava, R. M. Soumya, S. Chitragar, R. Safaya, S. H. Chandrashekhar, Alok Thakar

“…The term “aggressive papillary middle ear tumor” has recently been proposed to describe this more invasive type of middle ear tumor. …”
Get full text

Evaluation of the significance of tumor stromal patterns and peri-tumoral inflammation in head and neck squamous cell carcinoma with special reference to the Yamamoto–Kohama classification by Geet Bhuyan, Prabir Hazarika, Anju M. Rabha

“…Cancer-associated fibroblasts (CAFs) are the predominant cell type in tumor stroma and are important promoters of tumor progression. …”
Get full text

MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

Subjects: Get full text

Leydig Cell Tumor Associated with Testicular Adrenal Rest Tumors in a Patient with Congenital Adrenal Hyperplasia due to 11β-Hydroxylase Deficiency by Nadia Charfi, Mahdi Kamoun, Mouna Feki Mnif, Neila Mseddi, Fatma Mnif, Nozha Kallel, Basma Ben Naceur, Nabila Rekik, Hela Fourati, Emna Daoud, Zainab Mnif, Mourad Hadj Sliman, Tahia Sellami-Boudawara, Mohamed Abid

“…Chronic excessive adrenocorticotropic hormone (ACTH) stimulation may result in hyperplasia of ACTH-sensitive tissues in adrenal glands and other sites such as the testes, causing testicular masses known as testicular adrenal rest tumors (TARTs). Leydig cell tumors (LCTs) are make up a very small number of all testicular tumors and can be difficult to distinguish from TARTs. …”
Get full text

Tumor-associated-fibrosis and active collagen-CD44 axis characterize a poor-prognosis subtype of gastric cancer and contribute to tumor immunosuppression by Yingqi Yang, Haohan Sun, Hongkai Yu, Luyao Wang, Chang Gao, Haokun Mei, Xiaomeng Jiang, Minghui Ji

“…Abstract Background Tumor-associated fibrosis modifies the tumor microenvironment (TME), hinders the infiltration and activity of cytotoxic immune cells, and is a critical pathological process leading to the ineffectiveness of tumor immunotherapy in gastric cancer (GC). …”
Get full text

Carbon Material Hybrid Construction on an Aptasensor for Monitoring Surgical Tumors by Renyuan Ma, Subash C. B. Gopinath, Thangavel Lakshmipriya, Yeng Chen

“…Carcinoembryonic antigen (CEA) is a glycoprotein, one of the common tumor biomarkers, found at low levels in body fluids. …”
Get full text

Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors by Callisia N. Clarke, Paul Cockrum, Thomas J.R. Beveridge, Michelle Jerry, Donna McMorrow, Anh Thu Tran, Alexandria T. Phan

“…**Background:** Long-acting somatostatin analog therapy (LA-SSA) is recommended as first-line therapy for treatment of unresectable or metastatic neuroendocrine tumors (NETs). Understanding treatment sequencing and dosing patterns of LA-SSA is essential for clinical decision-making to provide value-based management of NETs. …”
Get full text

Diagnostic and Therapeutic Advances of RNAs in Precision Medicine of Gastrointestinal Tumors by Runhan Liu, Jiaxin Zhou, Xiaochen Chen, Jie Zhang, Qunzhi Chen, Xiaoming Liu, Kunhou Yao

Subjects: “…gastrointestinal tumors…”
Get full text