Neoadjuvant programmed death ligand-1 with chemotherapy versus chemotherapy alone for limited-stage small-cell lung cancer: a retrospective study by Zhi Yang, Yan-qing Wang, Xiujun Chang

Subjects: Get full text

Fast Hadamard-Encoded 7T Spectroscopic Imaging of Human Brain by Chan Hong Moon, Frank S. Lieberman, Hoby P. Hetherington, Jullie W. Pan

Subjects: Get full text

A 4-year-old Boy with a Red Nodule on His Hand: A Quiz by Riku Ishii, Noriyuki Otsuka, Takashi Anan, Yuhei Yamamoto, Taku Maeda

Subjects: “…Atypical Spitz tumor…”
Get full text

Identification of a novel immunogenic cell death-related classifier to predict prognosis and optimize precision treatment in hepatocellular carcinoma by Dongjing Zhang, Bingyun Lu, Qianqian Ma, Wen Xu, Qi Zhang, Zhiqi Xiao, Yuanheng Li, Ren Chen, An-jiang Wang

Subjects: Get full text

Identification of fatty acid anabolism patterns to predict prognosis and immunotherapy response in gastric cancer by Weijie Sun, Yanhong Xia, Feifan Jin, Jinghao Cao, Gaoping Wu, Keyi Li, Yanhua Yu, Yunyi Wu, Gaoqi Ye, Ke Xu, Dengpan Liu, Weidong Jin

Subjects: Get full text

A novel necroptosis-related gene signature predicts the prognosis and immunotherapeutic response in breast cancer through immune infiltration by Dezhi Lu, Sifang Qiu, Zhiqiang Zeng

Subjects: Get full text

Targeting Inhibition of Accumulation and Function of Myeloid-Derived Suppressor Cells by Artemisinin via PI3K/AKT, mTOR, and MAPK Pathways Enhances Anti-PD-L1 Immunotherapy in Melanoma and Liver Tumors by Mengqi Zhang, Lulu Wang, Wan Liu, Tian Wang, Francesco De Sanctis, Lifang Zhu, Guizhong Zhang, Jian Cheng, Qin Cao, Jingying Zhou, Aldo Tagliabue, Vincenzo Bronte, Dehong Yan, Xianchun Wan, Guang Yu

“…Targeting MDSCs by ART could significantly reduce tumor growth in various mouse models. More importantly, the ART therapy remarkably enhanced the efficacy of anti-PD-L1 immunotherapy in tumor-bearing mice through promoting antitumor T cell infiltration and proliferation. …”
Get full text

Application of diversified health education in patients with brain tumor-related epilepsy and their family members (多元化健康教育在脑肿瘤相关性癫痫患者及其家属中的应用研究) by LIU Qiaojun (刘巧俊), YANG Fan (杨帆)

“…Objective To explore the application effect of diversified health education inpatients with brain tumor-related epilepsy and their family members . …”
Get full text

Click Synthesis and Biologic Evaluation of ()- and ()-2-Amino-3-[1-(2-[F]Fluoroethyl)-1-[1,2,3]Triazol-4-yl]Propanoic Acid for Brain Tumor Imaging with Positron Emission Tomography by Jonathan McConathy, Dong Zhou, Stephany E. Shockley, Lynne A. Jones, Elizabeth A. Griffin, Hsiaoju Lee, Susan J. Adams, Robert H. Mach

“…In vivo biodistribution studies demonstrated that ( S )-[ 18 F]4 provided higher tumor uptake and higher tumor to brain ratios (15:1 at the 30- and 60-minute time points) compared to the ( R )-enantiomer (7:1 at the 30- and 60-minute time points). …”
Get full text

Technologically-Treated Polyclonal Affinity-Purified Antibodies to the Tumor Necrosis Factor-α, Brain Specific S-100 Protein and Histamine in Treatment of Functional Dyspepsia: Results of the Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial by Yu. O. Shulpekova, I. V. Maev, V. B. Grinevich, I. B. Khlynov, Yu. G. Shvarts, V. T. Ivashkin

Subjects: “…technologically-treated polyclonal affinity-purified antibodies to the tumor necrosis factor-α…”
Get full text

Multimodal Imaging of Integrin Receptor-Positive Tumors by Bioluminescence, Fluorescence, Gamma Scintigraphy, and Single-Photon Emission Computed Tomography Using a Cyclic RGD Peptide Labeled with a Near-Infrared Fluorescent Dye and a Radionuclide by W. Barry Edwards, Walter J. Akers, Yunpeng Ye, Philip P. Cheney, Sharon Bloch, Baogang Xu, Richard Laforest, Samuel Achilefu

“…Integrins, particularly the α v β 3 heterodimers, play important roles in tumor-induced angiogenesis and invasiveness. To image the expression pattern of the α v β 3 integrin in tumors through a multimodality imaging paradigm, we prepared a cyclic RGDyK peptide analogue (LS308) bearing a tetraazamacrocycle 1,4,7,10-tetraazacyclododecane- N, N′, N″, N‴ -tetraacetic acid (DOTA) and a lipophilic near-infrared (NIR) fluorescent dye cypate. …”
Get full text

PD-L1 monoclonal antibody alleviated MI injury of left ventricular function via modulating CD47/SHP2/SIRPα/SYK/FcγR signalings in tumor associated macrophages by Deyou Kong, Yongzhen Chen, Yajuan Yin, Zhikun Liu, Fang Yang, Xiaohong Li, Dongxing Shen, Jun Zhang

“…Heart tissue and breast cancer tumor samples were isolated, and the content of cGAMP was measured using LC-MS/MS. …”
Get full text

Relationship Between Short‐Term Outcomes and PD‐L1 Expression Based on Combined Positive Score and Tumor Proportion Score in Recurrent or Metastatic Head and Neck Cancers Treated With Anti‐PD‐1 Antibody Monotherapy by Akihiro Ohara, Taisuke Mori, Mai Itoyama, Kazuki Yokoyama, Shun Yamamoto, Ken Kato, Yoshitaka Honma

“…ABSTRACT Background PD‐L1 expression in tumors and immune cells is a biomarker for the efficacy of anti‐PD‐1 antibody (APA) therapy across diverse cancers. …”
Get full text

Role of 18F-PSMA-1007 PET/CT-derived quantitative volumetric tumor parameters in cytoreductive radical prostatectomy selection for patients with low-volume metastatic hormone-sensitive prostate cancer: a retrospective study by Junjie Fan, Ke Xu, Zhangdong Jiang, Chaosheng Gan, Hao Song, Guoqiang Gao, Guojing Wang, Qiyuan Kang, Liang Luo, Zhuonan Wang, Dalin He, XiaoYi Duan, Kaijie Wu

“…The whole-body PSMA-derived tumor volume (PSMA-TV) was defined as the total volume of whole-body PSMA-avid tumor lesions, and prostate PSMA-TV was defined as the volume of prostate PSMA-avid tumor lesions. …”
Get full text

Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway by Yanfang Liang, Qianqian Chen, Wenjing Du, Can Chen, Feifei Li, Jingying Yang, Jianyu Peng, Dongping Kang, Bihua Lin, Xingxing Chai, Keyuan Zhou, Jincheng Zeng

“…To date, little is known about the role of EBI3 in tumor microenvironment. In this study, firstly we assessed EBI3, IL-27p28, IL-12p35, gp130, and p-STAT3 expression with clinicopathological parameters of colorectal cancer (CRC) tissues; then we evaluated the antitumor T cell responses and tumor growth with a EBI3 blocking peptide. …”
Get full text

A high-valence bismuth(V) nanoplatform triggers cancer cell death and anti-tumor immune responses with exogenous excitation-free endogenous H2O2- and O2-independent ROS generation by Yizhang Tang, Xujiang Yu, Liangrui He, Meng Tang, Wenji Yue, Ruitong Chen, Jie Zhao, Qi Pan, Wanwan Li

“…NaBiVO3-PEG intratumorally administered initiates robust therapeutic efficacies against both primary and distant tumors and activates systemic immune responses to combat tumor metastasis. …”
Get full text

Immune‐dysregulation harnessing in myeloid neoplasms by Mohammad Jafar Sharifi, Ling Xu, Nahid Nasiri, Mehnoosh Ashja‐Arvan, Hadis Soleimanzadeh, Mazdak Ganjalikhani‐Hakemi

Subjects: Get full text

mRNA vaccines in the context of cancer treatment: from concept to application by Qiang Fu, Xiaoming Zhao, Jinxia Hu, Yang Jiao, Yunfei Yan, Xuchen Pan, Xin Wang, Fei Jiao

Subjects: Get full text

The Efficacy of Adalimumab Treatment in Pediatric Non-Infectious Uveitis: A Retrospective Cohort Study by Kübra Özdemir Yalçınsoy, Osman Özen, Yasemin Özdamar Erol, Pınar Çakar Özdal

Subjects: Get full text

Integrative prognostic modeling of ovarian cancer: incorporating genetic, clinical, and immunological markers by Aidi Lin, Feifei Xue, Chenxiang Pan, Lijiao Li

Subjects: Get full text