Periostin-mediated NOTCH1 activation between tumor cells and HSCs crosstalk promotes liver metastasis of small cell lung cancer by Linlin Lou, Keren Peng, Shumin Ouyang, Wen Ding, Jianshan Mo, Jiayu Yan, Xiaoxiao Gong, Guopin Liu, Jinjian Lu, Peibin Yue, Kai Zhang, Jian Zhang, Yan-dong Wang, Xiao-lei Zhang

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VACCIMEL, an allogeneic melanoma vaccine, efficiently triggers T cell immune responses against neoantigens and alloantigens, as well as against tumor-associated antigens by Ibel Carri, Ibel Carri, Erika Schwab, Juan Carlos Trivino, Erika M. von Euw, Morten Nielsen, Morten Nielsen, José Mordoh, María Marcela Barrio

“…Between 0,05 and 0,2% of these variants were also found in the tumors of three vaccinated patients; however, one patient with a high tumor mutational burden (TMB) shared 19,5% somatic variants. …”
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Developed in a Patient with Progressive Muscular Dystrophy: A Case Report and Review of the Literature by Ryo Miyagi, Toshihiko Nishisho, Shinjiro Takata, Yoshimitsu Shimatani, Shunichi Toki, Koichi Sairyo

“…Background. Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLS) is an intermediate or locally aggressive form of adipocytic soft tissue sarcoma. …”
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Enrichment of Cancer‐Associated Fibroblasts, Macrophages, and Up‐Regulated TNF‐α Signaling in the Tumor Microenvironment of CMS4 Colorectal Peritoneal Metastasis by Eirik Høye, Chakravarthi Kanduri, Annette Torgunrud, Susanne Lorenz, Bjørn Edwin, Stein G. Larsen, Åsmund A. Fretland, Vegar J. Dagenborg, Kjersti Flatmark, Christin Lund‐Andersen

“…This study aimed to explore the metastatic tumor microenvironment (TME) by comparing cell populations in colorectal liver (CLM), lung (mLu), and peritoneal (PM) metastases. …”
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DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells by Ignacio Melero, Ruth Conde-Garrosa, David Sancho, Santos Mañes, Alfonso R Sanchez-Paulete, Francisco J Cueto, Carlos del Fresno, Paola Brandi, Alexis J. Combes, Elena Hernández-García, Michel Enamorado, Christian P Bromley, Manuel J Gomez, Santiago Zelenay, Salvador Iborra, Matthew F. Krummel

“…To characterize the immune response, we performed flow cytometry and RNA-Seq of tumor-infiltrating cDC1s.Results Here, we found that cross-presentation of tumor antigens in the steady state was DNGR-1-independent. …”
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Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target by Guang-zhao Huang, Ze-qun Chen, Juan Wu, Ting-ru Shao, Chen Zou, Yi-long Ai, Xiao-zhi Lv

“…Increasing evidence indicated that the tumor microenvironment (TME) played a crucial role in cancer initiation and progression. …”
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Implications of the Incidental Finding of a MYCN Amplified Adrenal Tumor: A Case Report and Update of a Pediatric Disease Diagnosed in Adults by Anna Koumarianou, Panagiota Oikonomopoulou, Margarita Baka, Dimitrios Vlachodimitropoulos, Stylianos Argentos, Theodoros Piperos, Maria-Ioanna Christodoulou, Kakoulis Theodoulou, Theodoros Mariolis-Sapsakos

“…MYCN is a well-known oncogene overexpressed in different human malignancies including neuroblastoma, rhabdomyosarcoma, medulloblastoma, astrocytoma, Wilms’ tumor, and small cell lung cancer. While neuroblastoma is one of the most common childhood malignancies, in adults it is extremely rare and its treatment is based on pediatric protocols that take into consideration stage and genotypic features, such as MYCN amplification. …”
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Rare Double Primary Malignancies: A Pancreatic Gastrointestinal Stromal Tumor Mimicking as a Metastatic Lesion of Myoepithelial Carcinoma of Parotid Gland by Vania Myralda Giamour Marbun, Indah Jamtani, Ening Krisnuhoni, Sonar Soni Panigoro

“…Pancreatic gastrointestinal stromal tumors (PGISTs) are exceptionally rare, accounting for <5% of extra-gastrointestinal stromal tumors (EGISTs) and <1% of malignant pancreatic neoplasms. …”
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Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis by Abdel Mansouri, Lon D. Ridgway, Qingxiu Zhang, Francois X. Claret

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Use of the Google translate mobile application (audio mode) for perioperative management in a patient with language barrier undergoing intracranial tumor resection by Priya Thappa, Garima Choudhary, Hemant Bhagat, Prateek Arora

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Retraction: Long Noncoding RNA-EBIC Promotes Tumor Cell Invasion by Binding to EZH2 and Repressing E-Cadherin in Cervical Cancer. by PLOS One Editors

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Desmoplastic Small Round Cell Tumor, a “Floating Island” Pattern in Pleural Fluid Cytology: A Case Report and Review of the Literature by Hui Zhu, Emily Marie McMeekin, Charles D. Sturgis

“…Desmoplastic small round cell tumor (DSRCT) is a rare aggressive sarcoma with characteristic clinical and pathologic features. …”
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Vascularized fibular grafting following tumor resection demonstrates acceptable long-term outcomes in Denmark: a national retrospective cohort study by Christian Lind Nielsen, Daniel Thor Halberg Dybdal, Peter Vester-Glowinski, Lisa Lyngsie Hjalgrim, Pernille Edslev Wendtland, Birgitte Jul Kiil, Michael Melchior Bendtsen, Michael Mørk Petersen, Thomas Baad-Hansen

“… Background and purpose: Vascularized fibular grafting following tumor resection is an essential treatment option in limb salvage surgery. …”
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Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment by Tangyi Wang, Yadian Lei, Jingwei Sun, Li Wang, Yuxin Lin, Zhijing Wu, Shoude Zhang, Chengzhu Cao, Chengzhu Cao, Chengzhu Cao, Haiyan Wang, Haiyan Wang, Haiyan Wang

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Recurrent Renal Cell Carcinoma with Synchronous Tumor Growth in Azygoesophageal Recess and Duodenum: A Rare Cause of Anemia and Upper Gastrointestinal Bleeding by Vamshidhar R. Vootla, Muhammad Kashif, Masooma Niazi, Suresh K. Nayudu

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Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence by Pavithra Ayyanar, Suvradeep Mitra, Mohammed Imaduddin, Dillip K. Muduly

Subjects: “…brenner tumor…”
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Role of Colchicine Treatment in Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS): Real-Life Data from the AIDA Network by Antonio Vitale, Jurgen Sota, Laura Obici, Nicola Ricco, Maria Cristina Maggio, Marco Cattalini, Piero Ruscitti, Francesco Caso, Raffaele Manna, Ombretta Viapiana, Valeria Caggiano, Giacomo Emmi, Antonella Insalaco, Davide Montin, Francesco Licciardi, Alessandra Soriano, Lorenzo Dagna, Carlo Salvarani, Vittoria Lamacchia, José Hernández-Rodríguez, Roberto Giacomelli, Bruno Frediani, Alessandra Renieri, Luca Cantarini

“…To analyze the potential role of colchicine monotherapy in patients with tumor necrosis factor receptor associated periodic syndrome (TRAPS) in terms of control of clinical and laboratory manifestations. …”
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Author Correction: Predicting the tumor microenvironment composition and immunotherapy response in non-small cell lung cancer from digital histopathology images by Sushant Patkar, Alex Chen, Alina Basnet, Amber Bixby, Rahul Rajendran, Rachel Chernet, Susan Faso, Prashanth Ashok Kumar, Devashish Desai, Ola El-Zammar, Christopher Curtiss, Saverio J. Carello, Michel R. Nasr, Peter Choyke, Stephanie Harmon, Baris Turkbey, Tamara Jamaspishvili

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The Progression of Mycosis Fungoides During Treatment with Mogamulizumab: A BIO-MUSE Case Study of the Tumor and Immune Response in Peripheral Blood and Tissue by Angelica Johansson, Eirini Kalliara, Emma Belfrage, Teodor Alling, Paul Theodor Pyl, Anna Sandström Gerdtsson, Urban Gullberg, Anna Porwit, Kristina Drott, Sara Ek

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Maternal Circulating Concentrations of Tumor Necrosis Factor-Alpha, Leptin, and Adiponectin in Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis by Jie Xu, Yan Hong Zhao, Yun Ping Chen, Xiao Lei Yuan, Jiao Wang, Hui Zhu, Chun Mei Lu

“…We performed a systematic review and meta-analysis to determine whether maternal serum concentration of tumor necrosis factor-alpha (TNF-α), leptin, and adiponectin were associated with GDM. …”
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