Enhanced tumor self-targeting of lemon-derived extracellular vesicles by embedding homotypic cancer cell membranes for efficient drug delivery by Lu-Yao Yang, Guo-Wu Liang, Bing-Jie Cai, Ke-Min Xu, Yu-Jie Zhao, Xiao-Ting Xie, Yu-Lin Zhang, Chao-Qing Li, Guo-Jun Zhang

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RAS/BRAF Circulating Tumor DNA Mutations as a Predictor of Response to First-Line Chemotherapy in Metastatic Colorectal Cancer Patients by Jiannan Yao, Wanchun Zang, Yang Ge, Nathaniel Weygant, Pan Yu, Lei Li, Guanhua Rao, Zhi Jiang, Rui Yan, Linjia He, Yang Yu, Mulan Jin, Gang Cheng, Guangyu An

“…Background. Since circulating tumor DNA (ctDNA) offers clear advantages as a minimally invasive method for tumor monitoring compared with tumor tissue, we aimed to evaluate genotyping ctDNA using a next-generation sequencing- (NGS-) based panel to identify the prognostic value of mutation status in metastatic colorectal cancer (mCRC) patients with primary tumor resected and with subsequent lines of treatment in this study. …”
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Abdominal Tumor in a 14-Year-Old Adolescent: Imperforate Hymen, Resulting in Hematocolpos—A Case Report and Review of the Literature by George Marios Makris, Doris Macchiella, Dennis Vaidakis, Charalampos Chrelias, Marco Johannes Battista, Charalampos Siristatidis

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Ddx21 mutant peptide is an effective neoantigen in prophylactic lung cancer vaccines and activates long-term anti-tumor immunity by Zhe Zhang, Yimeng Xia, Yimeng Xia, Zhihong Wang, Yaxing Sun, Dan Pu, Yijia He, Ruixian Liu, Yanru Zhang, Yan Liu, Junzhi Yu, Shiyang Ning, Baisui Feng, Yaohe Wang, Na Wang

“…Our previous studies indicated that mice immunized with a prophylactic vaccine based on lung cancer cell lines KPL 160302S, derived from early-stage murine lung cancer tissues, exhibited a significantly extended survival period, with a strong anti-tumor immune response. While the vaccine based on KPL 160424S, derived from advanced-stage murine lung cancer tissues, failed to extend survival time and demonstrated limited capacity to stimulate anti-tumor immunity. …”
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MCT1 lactate transporter blockade re-invigorates anti-tumor immunity through metabolic rewiring of dendritic cells in melanoma by Camille Niveau, Mélanie Cettour-Cave, Stéphane Mouret, Eleonora Sosa Cuevas, Mylene Pezet, Benoît Roubinet, Hugo Gil, Florence De Fraipont, Ludovic Landemarre, Julie Charles, Philippe Saas, Caroline Aspord

“…Strikingly, modulation of the mTOR/AMPK-dependent metabolic pathways and/or the MCT1 lactate transporter rescue cDC2s and cDC1s from skewing by tumor-derived glycans, Sialyl-Tn antigen and Fucose, and restore anti-tumor T-cell fitness. …”
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Metastatic Cerebellar Gastrointestinal Stromal Tumor with Obstructive Hydrocephalus Arising from the Small Intestine: A Case Report and Review of the Literature by Kunitomo Sato, Toshihide Tanaka, Naoki Kato, Takuya Ishii, Toru Terao, Yuichi Murayama

“…Gastrointestinal stromal tumor (GIST) is defined as a c-kit-positive gastrointestinal, mesenteric, or omental mesenchymal tumor that very rarely metastasizes to the brain. …”
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Antianemic Treatment of Cancer Patients in German Routine Practice: Data from a Prospective Cohort Study—The Tumor Anemia Registry by Tilman Steinmetz, Jan Schröder, Margarete Plath, Hartmut Link, Michèle Vogt, Melanie Frank, Norbert Marschner

“…Patients were followed up for 12 weeks. 63% of the patients had inoperable solid tumors, 22% operable solid tumors, and 15% hematological malignancies. …”
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Hybrid deep learning approach for brain tumor classification using EfficientNetB0 and novel quantum genetic algorithm by Kerem Gencer, Gülcan Gencer

Subjects: “…Brain tumor…”
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Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors by Constantin Jotzu, Eckhard Alt, Gabriel Welte, Jie Li, Bryan T. Hennessy, Eswaran Devarajan, Srinivasalu Krishnappa, Severin Pinilla, Lilly Droll, Yao-Hua Song

“…Carcinoma-associated fibroblasts (CAF) are considered to contribute to tumor growth, invasion and metastasis. However, the cell type of origin remains unknown. …”
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Tumor-derived colorectal cancer organoids induce a unique Treg cell population by directing CD4+ T cell differentiation by Sonia Aristin Revilla, Cynthia L. Frederiks, Stefan Prekovic, Enric Mocholi, Onno Kranenburg, Paul J. Coffer

“…Summary: In colorectal cancer (CRC), increased numbers of tumor-infiltrating CD4+ regulatory T (Treg) cells correlate with tumor development, immunotherapy failure, and poor prognosis. …”
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Serum levels of tumor necrosis factor-alpha and vascular endothelial growth factor as markers of disease activity in patients with axial spondyloarthritis by Mahendran Bhuvanesh, Chilkuri Balaji, Chinnadurai Saranya, Ramamoorthy Ramesh, Trichangode Natesan Tamilselvam, Sankaralingam Rajeswari

“…This study aims to investigate the role of vascular endothelial growth factor (VEGF) and tumor necrosis factor-alpha (TNF-α) as markers of disease activity in patients with axSpA. …”
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Letter to the Editor Regarding Our Case Report on 'Solitary Submandibular Schwannoma Mimicking a Salivary Gland Tumor in a Child' by Wong Kim Yew RICHARD, Nur Kamilia Mohd MOHSIN

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EUS-FNA for a Pancreatic Neuroendocrine Tumor in a Four-Year-Old Daughter of a Woman Exposed to Radiation at Chernobyl by Jesse Lachter, Marc S. Arkovitz, Sergey Postovski, Julian M. Waldner, Ron Shaoul, Offir Ben Ishay, Yoram Kluger

“…The diagnosis, management, and followup of children with this rare tumor are discussed.…”
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ncRNA-Mediated High Expression of LPCAT1 Correlates with Poor Prognosis and Tumor Immune Infiltration of Liver Hepatocellular Carcinoma by Qiu Sun, Xudong Liu, Qunlong Peng, Lei Hu, Xiaochun Jiang

“…Immune cell infiltration of LPCAT1 in LIHC was finally investigated via Tumor Immune Estimation Resource (TIMER). Result. …”
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Oncogene OSTM1 Promotes Gastric-Cancer Metastasis by Modulating the Metastatic Microenvironment Through Altered Tumor-Cell Autocrine Signaling by Yucheng Tang, Yi Guo, Jiangyi Feng, Ziwei Wang

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Preliminary Study the Effect of Galbanic Acid on the Efficacy of Radiation Therapy on O26 Tumor Cells Implanted In Balb-C Mice by Morteza Rezaei kahkha, Shokouhozaman Soleymanifard, mehrdad iranshahi, samaneh soudmand salarabadi, elham tavakkoli, amir fotovati, Najme rezaei dovom

“…The purpose of this study is to investigate the effect of Galbanic acid on C26 tumor radiation sensitivity and The main challenge of this study is to deliver the drug to the tumor cells due to the hydrophobicity of Galbanic acid.Material and Methods: 28 inbred male Balb/C mice were injected subcutaneously with 500,000 C26 cells into the right flank. …”
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Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks by Deependra Rastogi, Prashant Johri, Massimo Donelli, Seifedine Kadry, Arfat Ahmad Khan, Giuseppe Espa, Paola Feraco, Jungeun Kim

Subjects: “…Brain tumor…”
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CHI-KAT8i5 suppresses ESCC tumor growth by inhibiting KAT8-mediated c-Myc stability by Dandan Zhang, Ming Jiang, Pan Li, Kyle Vaughn Laster, Dengyun Zhao, Yafei Zhi, Huifang Wei, Wenna Nie, Yunfeng Gao, Qiong Wu, Pu Xiang, Xinyu He, Kangdong Liu, Zigang Dong

“…Summary: The integrated analysis of histone modifier enzymes in solid tumors, especially in esophageal squamous cell carcinoma (ESCC), is still inadequate. …”
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Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation by Lin Cheng, Sheng Xu, Yu‐feng Wang, Sheng‐wei Li, Bin Li, Xiao‐Guang Li

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Plant-derived Pembrolizumab in conjugation with IL-15Rα-IL-15 complex shows effective anti-tumor activity by Kaewta Rattanapisit, Pipob Suwanchaikasem, Christine Joy I. Bulaon, Shiying Guo, Waranyoo Phoolcharoen

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